• Title/Summary/Keyword: mean stress sensitivity

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What do patients with psoriasis think about the causes of their disease and use for psoriasis?

  • Gonul, Muzeyyen;Cakmak, Seray Kulcu;Gul, Ulker;Biyikli, Zeynep
    • CELLMED
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    • v.2 no.1
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    • pp.8.1-8.4
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    • 2012
  • There are few reports about the beliefs of psoriasis patients related to their disorder and therapy modalities except for the medical ones. We aimed to investigate the beliefs of psoriasis patients about their disorders, where they had attended therapies unrelated to dermatologists and what modality of unconventional therapies they used for psoriasis in Turkey. The study was performed on 141 psoriasis patients. The age, sex, education status and the number of visits to the dermatology clinics were recorded. How the patients decided to visit the dermatology clinic (themselves, directed by others), where they attended for treatment of psoriasis outside of the dermatologist, what they think about the causes of their disease and what they used for treatment of psoriasis were asked. The mean age of the patients was $33.44{\pm}15.13$ years. The patients whose ages were over 30 years significantly more went to dermatology clinics. 68.1% of the patients attended the dermatology clinic based on the individual decision, 18.4% were directed by family members and 5.7% by friends. 45.4% of the patients believed that stress was the cause of their disease. 54.6% of the patients had used at least one type of unconventional therapy for psoriasis. The most frequently used unconventional therapy forms were herbal (24.1%) and spiritual therapies (22%). One conclusion is psoriasis patients need education about their diseases. Dermatologists should have information about the tendencies of the patients and approach the patients with sensitivity and empathy and give objective knowledge about psoriasis.

Effect That Type Gets in Consumer Communication : Product Participation Level and Internet Word-of-mouth -Laying stress on purchase review of product and Internet shopping mall by FCB Model- (제품 관여수준과 인터넷 구전메시지 유형이 소비자 커뮤니케이션에 미치는 영향 -FCB 모델에 따른 제품과 인터넷 쇼핑몰의 구매 댓글을 중심으로-)

  • Chin, Hong-Kun;Lee, Eun-Joo
    • Management & Information Systems Review
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    • v.22
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    • pp.85-115
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    • 2007
  • Following is discovered in this study by some. First, attribute(product/non- product) of that truth that get through experiment of this study is WOM deduced result that have statistical meaning in dependent variable which is public trust only in this study. Specially, information by word of mouth type received High positive response more with non-product information by word of mouth attribute than the product attribute in all experiment products that is parted according to involvement. Consumer's response by involvement level of product can affect for site attitude, public trust, and intention to purchase by second. For example, consumer's site attitude has induced the most positive response, and can confirm positive response of High consumer most in that involvement sensitivity product in that participation reason type product and could confirm response that is the most positive in that involvement reason product even if there is for intention to purchase. Result of this study is grasped that have High mean value relatively in site attitude, product attitude, information by word of mouth effect, public trust, brand attitude, purchase intention etc. generally that product involvement and information by word of mouth attribute are interrelation by third. This can change fairly data processing process according to consumer's Involvement Level, behavior deterministic process, consumer's action with attitude formation process, and involvement for products. High occasion than is low incline more efforts in information retrieval and is discreet result such as study finding of produce.

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Performance Evaluation of Deep Neural Network (DNN) Based on HRV Parameters for Judgment of Risk Factors for Coronary Artery Disease (관상동맥질환 위험인자 유무 판단을 위한 심박변이도 매개변수 기반 심층 신경망의 성능 평가)

  • Park, Sung Jun;Choi, Seung Yeon;Kim, Young Mo
    • Journal of Biomedical Engineering Research
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    • v.40 no.2
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    • pp.62-67
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    • 2019
  • The purpose of this study was to evaluate the performance of deep neural network model in order to determine whether there is a risk factor for coronary artery disease based on the cardiac variation parameter. The study used unidentifiable 297 data to evaluate the performance of the model. Input data consists of heart rate parameters, which are SDNN (standard deviation of the N-N intervals), PSI (physical stress index), TP (total power), VLF (very low frequency), LF (low frequency), HF (high frequency), RMSSD (root mean square of successive difference) APEN (approximate entropy) and SRD (successive R-R interval difference), the age group and sex. Output data are divided into normal and patient groups, and the patient group consists of those diagnosed with diabetes, high blood pressure, and hyperlipidemia among the various risk factors that can cause coronary artery disease. Based on this, a binary classification model was applied using Deep Neural Network of deep learning techniques to classify normal and patient groups efficiently. To evaluate the effectiveness of the model used in this study, Kernel SVM (support vector machine), one of the classification models in machine learning, was compared and evaluated using same data. The results showed that the accuracy of the proposed deep neural network was train set 91.79% and test set 85.56% and the specificity was 87.04% and the sensitivity was 83.33% from the point of diagnosis. These results suggest that deep learning is more efficient when classifying these medical data because the train set accuracy in the deep neural network was 7.73% higher than the comparative model Kernel SVM.

Evaluation of NDVI Retrieved from Sentinel-2 and Landsat-8 Satellites Using Drone Imagery Under Rice Disease (드론 영상을 이용한 Sentinel-2, Landsat-8 위성 NDVI 평가: 벼 병해 발생 지역을 대상으로)

  • Ryu, Jae-Hyun;Ahn, Ho-yong;Na, Sang-Il;Lee, Byungmo;Lee, Kyung-do
    • Korean Journal of Remote Sensing
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    • v.38 no.6_1
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    • pp.1231-1244
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    • 2022
  • The frequency of exposure of field crops to stress situations is increasing due to abnormal weather conditions. In South Korea, large-scale diseases in representative paddy rice cultivation area were happened. There are limits to field investigation on the crop damage due to large-scale. Satellite-based remote sensing techniques are useful for monitoring crops in cities and counties, but the sensitivity of vegetation index measured from satellite under abnormal growth of crop should be evaluated. The goal is to evaluate satellite-based normalized difference vegetation index (NDVI) retrieved from different spatial scales using drone imagery. In this study, Sentinel-2 and Landsat-8 satellites were used and they have spatial resolution of 10 and 30 m. Drone-based NDVI, which was resampled to the scale of satellite data, had correlation of 0.867-0.940 with Sentinel-2 NDVI and of 0.813-0.934 with Landsat-8 NDVI. When the effects of bias were minimized, Sentinel-2 NDVI had a normalized root mean square error of 0.2 to 2.8% less than that of the drone NDVI compared to Landsat-8 NDVI. In addition, Sentinel-2 NDVI had the constant error values regardless of diseases damage. On the other hand, Landsat-8 NDVI had different error values depending on degree of diseases. Considering the large error at the boundary of agricultural field, high spatial resolution data is more effective in monitoring crops.

Changes in expression of monocarboxylate transporters, heat shock proteins and meat quality of Large White Yorkshire and Ghungroo pigs during hot summer period

  • Parkunan, Thulasiraman;Das, Arun K.;Banerjee, Dipak;Mohanty, Niharika;Paul, Avishek;Nanda, P.K.;Biswas, TK;Naskar, Syamal;Bag, Sadhan;Sarkar, Mihir;Mohan, Narayana H.;Das, Bikash Chandra
    • Asian-Australasian Journal of Animal Sciences
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    • v.30 no.2
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    • pp.246-253
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    • 2017
  • Objective: Present study explores the effect of hot summer period on the glycolytic rate of early post-mortem meat quality of Ghungroo and Large White Yorkshire (LWY) pig and comparative adaptability to high temperature between above breeds by shifting the expression of stress related genes like mono-carboxylate transporters (MCTs) and heat shock proteins (HSPs). Methods: Healthy pigs of two different breeds, viz., LYW and Ghungroo (20 from each) were maintained during hot summer period (May to June) with a mean temperature of about $38^{\circ}C$. The pigs were slaughtered and meat samples from the longissimus dorsi (LD) muscles were analyzed for pH, glycogen and lactate content and mRNA expression. Following 24 h of chilling, LD muscle was also taken from the carcasses to evaluate protein solubility and different meat quality measurements. Results: LWY exhibited significantly (p<0.01) higher plasma cortisol and lactate dehydrogenase concentration than Ghungroo indicating their higher sensitivity to high temperature. LD muscle from LWY pigs revealed lower initial and ultimate pH values and higher drip loss compared to Ghungroo, indicating a faster rate of pH fall. LD muscle of Ghungroo had significantly lower lactate content at 45 min postmortem indicating normal postmortem glycolysis and much slower glycolytic rate at early postmortem. LD muscle of LWY showed rapid postmortem glycolysis, higher drip loss and higher degrees of protein denaturation. Ghungroo exhibited slightly better water holding capacity, lower cooking loss and higher protein solubility. All HSPs (HSP27, HSP70, and HSP90) and MCTs (MCT1, MCT2, and MCT4) in the LD muscle of pigs inclined to increase more in Ghungroo than LWY when exposed to high temperature. Conclusion: Effect of high temperature on the variation of HSPs and MCTs may play a crucial role in thermal tolerance and adaptation to different climatic conditions, pH regulation, muscle acidification, drip loss, protein denaturation and also in postmortem meat quality development.

Dynamic Deformation Properties of Coarse Granular Materials with Respect to Gradation Characteristics (조립재료의 입도특성에 따른 동적 변형특성 평가)

  • Ha, Ik-Soo;Kim, Nam-Ryong
    • Journal of the Korean Geotechnical Society
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    • v.29 no.8
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    • pp.5-14
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    • 2013
  • Coarse granular geomaterials containing large gravels are broadly used for construction of large geotechnical systems such as dams, levees, railways and backfills. It is necessary to evaluate deformation characteristics of these materials for dynamic analysis, e.g. seismic design. This study presents evaluation of dynamic deformation characteristics of coarse materials using large scale resonant column testing apparatus, which uses specimens with 200 mm in diameter and 400 mm in height, and the effects of gradation characteristics on maximum shear modulus, shear modulus reduction curve and damping characteristics were investigated. From experimental study using rock-fill materials for a dam, we could see that the largest or mean particle size affects the shape of shear modulus reduction curve. When the specimens are prepared under the same conditions for maximum particle size, the coefficient of uniformity affects the confining stress exponent of maximum shear modulus. It could be concluded that the maximum particle size is an factor which affects shear modulus reduction curve, and that the coefficient of uniformity is for small strain shear modulus, especially for the sensitivity to confining stress.

Analysis of Influencing Factors Related to Health Promotion Behavior in Hospital Radiological Technologists (종합병원 방사선사의 건강증진행위 관련요인 분석)

  • Ko, Jong-Kyung;Kwon, Duk-Mun;Kang, Yeong-Han
    • Journal of radiological science and technology
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    • v.32 no.4
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    • pp.381-391
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    • 2009
  • Purposes : The purpose of this study was to analyze factors that could affect health of radiological technologists, which is useful for health care and development of programs for health promotion. Methods : Subjects were 234 of radiological technologists who work in general hospitals. Some questionnaires were made about perceptions of health condition and promotional behavior of health for this study. The questionnaires of health perception were 20 items that consist of the present condition of health, health concern and sensitivity. The reliability was sufficient(Cronbach's $\alpha=0.79$). The other questionnaires about health promotion behavior were 47 items that consist of self-realization, health responsibility, exercise, nutrition, personal relationships, and stress management. The results turned out to bewas sufficient (Cronbach's $\alpha=0.93$). Every data was treated statistically, comparison of average(t-test, ANOVA), correlation, and multiple regression. Results : Related factors to health promotion behavior were age, marriage, salary, class of one's position, career, employment, and religion, in general features. In health life habit, related factors were smoke and exercise. Results of health promotion behavior was 2.90 of mean score, 0.37 of standard deviation. Correlations between factors of health perception and health promotion behavior was positive(p<0.01). Health promotion behavior were affected by sensitivity, presents condition of health, exercise, smoke, career. Sensitivity was the most affectable variable, which means that promotional behavior score became higher and higher as the score of sensitivity and present condition were increased. In addition, persons who exercise regularly, had been smoked, and has higher career showed higher score of promotional behavior. Conclusion : Radiological technologists have to keep their health, trying not to infected by a disease. Most of all, no smoking and regular exercise are the most important thing to all of members.

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Prediction of Improvement of Hibernating Myocardium after Coronary Artery Bypass Grafting -The role of dobutamine stress echocardiography- (동면심근을 가진 관상동맥 환자의 수술 후 기능회복의 예측에 대한 임상적 고찰 - Dobutamine 심초음파의 역할 -)

  • 유경종;강면식;이교준;김대준;임세중;정남식
    • Journal of Chest Surgery
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    • v.31 no.8
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    • pp.776-780
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    • 1998
  • Background: In patients with coronary artery disease, dysfunctional hypoperfused myocardium at rest may represent either nonviable or viable hibernating myocardium. Two-dimensional echocardiography can detect regional wall motion abnormalities resulting from myocardial ischemia by dobutamine infusion. The purpose of the present study was to identify the prediction of improvement of regional left ventricular(LV) function after surgical revascularization. Materials and methods: Sixteen patients with chronic regional LV dysfunction underwent dobutamine stress echocardiography(DSE) (dobutamine: baseline, 5, 10, 20$\mu$g/kg/min) before coronary artery bypass grafting(CABG) and underwent echocardiography at least 2 months after CABG. Results: All patients were male with mean age of 58 years ranging from 42 to 73 years. The mean LV ejection fraction was 41.8% with a range from 19% to 55%. During DSE, there were no complications, also, there were no operative morbidities or mortalities. Improvement of wall motion within the dysfunctional myocardium was found in 8(50%) of 16 patients in DSE. Among them, 6 patients(75%) showed functional recovery after CABG. Another 8 patients did not show improvement of wall motion in DSE. But among them, 3 patients(38%) showed functional recovery after CABG. 84 dysfunctional segments were found in 256 segments of 16 patients. Improvement of wall motion was found in 34 of 84 segments in DSE. Among them, 23 segments(74%) showed functional recovery after CABG. Another 53 segments did not show improvement of wall motion in DSE. But among them, 12 segments(23%) showed functional recovery after CABG. The sensitivity and specificity of DSE for the prediction of postoperative improvement of segmental wall motion were 66% and 84%, respectively. The positive and negative predictive value of DSE were 74% and 77%, respectively. In patients with chronic regional LV dysfunction, think that DSE is a good predictor of the improvement of dysfunctional segments after CABG.

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Solving Probability Constraint in Robust Optimization by Minimizing Percent Defective (불량률 최소화를 통한 강건 최적화의 확률제한조건 처리)

  • Lee, Kwang Ki;Park, Chan Kyoung;Kim, Geun Yeon;Lee, Kwon Hee;Han, Sang Wook;Han, Seung Ho
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.37 no.8
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    • pp.975-981
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    • 2013
  • A robust optimization is only one of the ways to minimize the effects of variances in design variables on the objective functions at the preliminary design stage. To predict the variances and to formulate the probabilistic constraints are the most important procedures for the robust optimization formulation. Though several methods such as the process capability index and the six sigma technique were proposed for the prediction and formulation of the variances and probabilistic constraints, respectively, there are few attempts using a percent defective which has been widely applied in the quality control of the manufacturing process for probabilistic constraints. In this study, the robust optimization for a lower control arm of automobile vehicle was carried out, in which the design space showing the mean and variance sensitivity of weight and stress was explored before robust optimization for a lower control arm. The 2nd order Taylor expansion for calculating the standard deviation was used to improve the numerical accuracy for predicting the variances. Simplex algorithm which does not use the gradient information in optimization was used to convert constrained optimization into unconstrained one in robust optimization.

Effects of Central Interleukin-1 on the Cardiovascular Response in Hemorrhaged Rats

  • Kang, Joon-Ho;Jang, Jae-Hee;Ahn, Dong-Kuk;Park, Jae-Sik
    • The Korean Journal of Physiology and Pharmacology
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    • v.8 no.2
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    • pp.89-94
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    • 2004
  • The arterial pressure is regulated by the nervous and humoral mechanisms. The neuronal regulation is mostly carried out by the autonomic nervous system through the rostral ventrolateral medulla (RVLM), a key area for the cardiovascular regulation, and the humoral regulation is mediated by a number of substances, including the angiotensin (Ang) II and vasopressin. Recent studies suggest that central interleukin-1 (IL-1) activates the sympathetic nervous system and produces hypertension. The present study was undertaken to elucidate whether IL-1 and Ang II interact in the regulation of cardiovascular responses to the stress of hemorrhage. Thus, Sprague-Dawley rats were anesthetized and both femoral arteries were cannulated for direct measurement of arterial pressure and heart rate (HR) and for inducing hemorrhage. A guide cannula was placed into the lateral ventricle for injection of IL-1 $(0.1,\;1,\;10,\;20\;ng/2\;{\mu}l)$ or Ang II $(600\;ng/10\;{\mu}l)$. A glass microelectrode was inserted into the RVLM to record the single unit spike potential. Barosensitive neurons were identified by an increased number of single unit spikes in RVLM following intravenous injection of nitroprusside. I.c.v. $IL-1\;{\beta}$ increased mean arterial pressure (MAP) in a dose-dependent fashion, but HR in a dose-independent pattern. The baroreceptor reflex sensitivity was not affected by i.c.v. $IL-1\;{\beta}$. Both i.c.v. $IL-1\;{\alpha}\;and\;{\beta}$ produced similar increase in MAP and HR. When hemorrhage was induced after i.c.v. injection of $IL-1\;{\beta}$, the magnitude of MAP fall was not different from the control. The $IL-1\;{\beta}$ group showed a smaller decrease in HR and a lower spike potential count in RVLM than the control. MAP fall in response to hemorrhage after i.c.v. injection of Ang II was not different from the control. When both IL-1 and Ang II were simultaneously injected i.c.v., however, MAP fall was significantly smaller than the control, and HR was increased rather than decreased. These data suggest that IL-1, a defense immune mediator, manifests a hypertensive action in the central nervous system and attenuates the hypotensive response to hemorrhage by interaction with Ang II.