• Asian Pacific Journal of Cancer Prevention
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• v.16 no.16
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• pp.6923-6928
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• 2015

Background: Early detection of various kinds of cancers nowadays is needed including colorectal cancer due to the highly significant effects in improving cancer treatment. The aim of this study was to evaluate the potential value of adiponectin, visfatin and resistin as early biomarkers for colorectal cancer patients. Materials and Methods: Serum levels of adiponectin, visfatin and resistin were measured by a sandwich-enzyme-linked (ELISA) assay technique in 114 serum samples comprising 34 patients with colorectal cancer (CRC), 27 with colonic polyps (CP), 24 with inflammatory bowel disease (IBD) and 29 healthy controls. The diagnostic accuracy of each serum marker was evaluated using receiver-operating characteristic (ROC) curve analysis. Results: The mean concentration of adiponectin was significantly higher in CRC and CP groups than IBD and control groups (P-value <0.05). Also the mean concentration of serum resistin was significantly elevated in the IBD and control groups compared to CRC and CP groups (P-value = 0.014). However, no significant difference was noted in patients of the CRC and CP groups. On the other hand, the mean concentration of visfatin was significantly elevated in CRC and control groups compared to CP and IBD groups (P-value = 0.03). ROC analysis curves for the studied markers revealed that between CRC and IBD groups serum level of adiponectin had a sensitivity of 76.7% and a specificity of 76% at a cut off value of 3940, +LR being 3.2 and -LR 0.31 with AUC 0.852, while serum level of adiponectin between CP and IBD had a sensitivity of 77.8% and a specificity of 75% at a cut off value of 3300, with +LR=3.11 and -LR = 0.3 with AUC 0.852. On the other hand the serum level of visfatin between CRC and CP groups had a sensitivity of 65.5% and a specificity of 66.7 at a cut off value of 2.4, +LR being 1.67 and -LR 0.52 with AUC 0.698. Also the serum level of resistin had a sensitivity of 62.5% and a specificity of 70.3% at a cut off value of 24500, with +LR=2.1 and -LR = 0.53 with AUC 0.685 between control and other groups. On the other hand by comparing control vs CP groups resistin had a sensitivity of 81.8% and a specificity of 70.8% at a cut off value of 17700, with +LR=2.8 and -LR = 0.26 with AUC 0.763 while visfatin had a sensitivity of 68.2% and a specificity of 70.8% at a cut off value of 2.7, with +LR=2.34 and -LR = 0.0.45 with AUC 0.812. Conclusions: These findings support potential roles of adiponectin, visfatin and resistin in early detection of CRC and discrimination of different groups of CRC, CP or IBD patients from normal healthy individuals.

• Journal of the Optical Society of Korea
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• v.14 no.2
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• pp.152-162
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• 2010

This study examined the effects of surround luminance on the shape of the spatial luminance contrast sensitivity function (CSF). The reduction in brightness of uniform neutral patches shown on a computer controlled display screen is also assessed to explain the change of CSF shape. Consequently, a large amount of reduction in contrast sensitivity at middle spatial frequencies can be observed; however, the reduction is relatively small for low spatial frequencies. In general, the effect of surround luminance on the CSF appears similar to that of mean luminance. Reduced CSF responses result in less power of the filtered image; therefore, the stimulus should appear dimmer with a higher surround luminance.

• 한국정보통신설비학회:학술대회논문집
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• 2006.08a
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• pp.235-240
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• 2006

In order to enhance receive sensitivity in noisy environment, the previous initial synchronization method of GPS receiver for reference stations adopts not only the coherent integration method but also the non-coherent integration method. However, the previous GPS initial synchronization method causes the non-coherent integration loss, which is a dominant factor among the signal acquisition losses in noisy environment. And the non-coherent integration loss increases with the strength of noise signal. In this pa-per, a GPS initial synchronization method is proposed to enhance receive sensitivity of GPS receiver for reference stations in noisy environment. This paper presents that the proposed GPS initial synchronization method suppresses the non-coherent integration loss. Furthermore, with regard to the mean acquisition time, it is shown that the number of the search cells of the proposed GPS initial synchronization method is much fewer than that of the previous GPS initial synchronization method.

• Asia-Pacific Journal of Atmospheric Sciences
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• v.54 no.4
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• pp.639-648
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• 2018

The pyranometer for observing the solar radiation reaching the surface of the earth is manufactured by various companies around the world. The sensitivity of the pyranometer at the observatory is required to be properly controlled based on the reference value of the World Radiometric Center (WRC) and the observatory environment; otherwise, the observational data may be subject to a large error. Since the sensitivity of the pyranometer can be calibrated in an indoor or outdoor calibration, this study used a CSTMUSS-4000C Integrating Sphere by Labsphere Inc. (USA) to calibrate the sensitivity of CMP22 pyranometer by Kipp&Zonen Inc. (Netherlands). Consequently, the factory sensitivity of CMP22 was corrected from $8.68{\mu}V{\cdot}(Wm^{-2})^{-1}$ to $8.98{\mu}V{\cdot}(Wm^{-2})^{-1}$, and the result from the outdoor calibration according to the observatory environment was $8.90{\mu}V{\cdot}(Wm^{-2})^{-1}$. After the indoor calibration of the pyranometer sensitivity, the root mean square error (RMSE) of the observational data at the observatory on a clear day without clouds (July 13, 2017) was $7.11Wm^{-2}$ in comparison to the reference pyranometer. After the outdoor calibration of the pyranometer sensitivity based on these results, the RMSE of the observational data was $1.74Wm^{-2}$ on the same day. Periodic inspections are required because the decrease of sensitivity over time is inevitable in the pyranometer data produced at the observatory. The initial sensitivity after indoor calibration ($8.98{\mu}V{\cdot}(Wm^{-2})^{-1}$) is important, and the sensitivity after outdoor calibration ($8.90{\mu}V{\cdot}(Wm^{-2})^{-1})$ can be compared to the data at the Baseline Surface Radiation Network (BSRN) or can be used for various studies and daily applications.

• The Journal of Korean Society for School & Community Health Education
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• v.22 no.3
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• pp.41-54
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• 2021

Objectives: This study aimed to confirm the degree of gender sensitivity, gender role conflict, nursing professionalism of nursing students and the factors that affect nursing professionalism. Methods: During Jan. 19 to Feb. 5 in 2021, the structured questionnaire was used for 187 nursing students by on-line research methods. Data were analyzed by descriptive analysis, mean comparison(t-test, ANOVA), correlation analysis(Pearson's correlation coefficient) and multiple regression using SPSS/WIN 25.0. Results: The gender sensitivity had positive relationship with nursing professionalism, and gender role conflict had negative relationship with nursing professionalism. And the prediction factors influencing nursing professionalism were major satisfaction, gender sensitivity and gender role conflict. The total variance was 8.2% by predictors. Conclusions: In order to improve the nursing professionalism of nursing students, various ways to increase the satisfaction level of major should be sought, and program should be prepared to improve gender sensitivity and reduce gender role conflict.

• The Korean Journal of Pain
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• v.23 no.2
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• pp.147-150
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• 2010

Background: Chronic low back pain can be a manifestation of lumbar degenerative disease, herniation of intervertebral discs, arthritis, or lumbar stenosis. When nerve roots are compromised, low back pain, with or without lower extremity involvement, may occur. Local inflammatory processes play an important role in patients with acute lumbosciatic pain. The purpose of this study was to assess the value of erythrocyte sedimentation rate (ESR) and high sensitivity C-reactive protein (hsCRP) measurements in patients with chronic low back pain or radiculopathy. Methods: ESR and hsCRP were measured in 273 blood samples from male and female subjects with low back pain and/or radiculopathy due to herniated lumbar disc, spinal stenosis, facet syndrome, and other diseases. The hsCRP and ESR were measured prior to lumbar epidural steroid injection. Results: The mean ESR was 18.8 mm/h and mean hsCRP was 1.1 mg/L. ESR had a correlation with age. Conclusions: A significant systemic inflammatory reaction did not appear to arise in patients with chronic low back pain.

• Journal of the Korean Society of Safety
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• v.23 no.4
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• pp.30-35
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• 2008

The present study has been conducted to examine the effect of grid resolution on the predicted results for electric cable fire using pyrolysis model in FDS(Fire Dynamics Simulator, version 5). The grid independent test for different grid resolutions has been performed for a PE coating cable and the grid resolution is defined by the non-dimensional characteristic length of fire and mean grid size. The calculated maximum heat release rate and mean flame spread rate were almost constant for higher grid resolution of 20${\sim}$25 and the computing time for the grid resolution takes approximately 20hours to solve flame propagation with pyrolysis model. The geometrical simplification of a electric cable dose not greatly affect on the maximum heat release rate and flame spread rate and the rectangular approximation of cable shape gives acceptable result comparing with the round cable with stepwise grid.

• International Journal of Reliability and Applications
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• v.16 no.2
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• pp.99-111
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• 2015

In this paper, we study the reliability analysis of a repairable system with two types of failure in which switching failures and reboot delay are considered. Let units in this system be cold standby, and failure rate and repair rate of [type1, type2] components be exponentially distributed. The expressions of reliability characteristics - such as the system reliability and the mean time to system failure MTTF - are derived. We use several cases to graphically analyze the effect of various system parameters on the system reliability and MTTF. We also perform a sensitivity analysis of the reliability characteristics with changes in specific values of the system's parameters.

• Communications for Statistical Applications and Methods
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• v.19 no.1
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• pp.169-175
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• 2012

The sensitivity of the performance measures such as the mean and the standard deviation of the queue length and the blocking probability with respect to the moments of the service time are numerically investigated. The service time distribution is fitted with phase type(PH) distribution by matching the first three moments of service time and the M/G/c retrial queue is approximated by the M/PH/c retrial queue. Approximations are compared with the simulation results.

• Journal of the Korean Operations Research and Management Science Society
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• v.17 no.1
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• pp.67-75
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• 1992

In this paper, by using perturbation analysis method, We find the sensitivity of the mean busy cycle with respect to means interrival time in M/M/1 Queue. We show that the Perturbation analysis estimate can be expressed as a sum of the infinitesimal perturbation analysis (IPA) estimate and the effect caused by changes in transition probabilities, thus explaining why IPA estimates are not consistent in general.