• 대한수학회보
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• 제54권3호
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• pp.1081-1094
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• 2017

For a poset $P=(X,{\leq}_P)$, the linear discrepancy of P is the minimum value of maximal differences of all incomparable elements for all possible labelings. In this paper, we find a lower bound and an upper bound of the linear discrepancy of a product of two posets. In order to give a lower bound, we use the known result, $ld({\mathbf{m}}{\times}{\mathbf{n}})={\lceil}{\frac{mn}{2}}{\rceil}-2$. Next, we use Dilworth's chain decomposition to obtain an upper bound of the linear discrepancy of a product of a poset and a chain. Finally, we give an example touching this upper bound.

• 대한수학회지
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• 제59권5호
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• pp.927-944
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• 2022

Let $\vec{p}{\in}(0,\;1]^n$ be an n-dimensional vector and A a dilation. Let $H^{\vec{p}}_A(\mathbb{R}^n)$ denote the anisotropic mixed-norm Hardy space defined via the radial maximal function. Using the known atomic characterization of $H^{\vec{p}}_A(\mathbb{R}^n)$ and establishing a uniform estimate for corresponding atoms, the authors prove that the Fourier transform of $f{\in}H^{\vec{p}}_A(\mathbb{R}^n)$ coincides with a continuous function F on ℝⁿ in the sense of tempered distributions. Moreover, the function F can be controlled pointwisely by the product of the Hardy space norm of f and a step function with respect to the transpose matrix of A. As applications, the authors obtain a higher order of convergence for the function F at the origin, and an analogue of Hardy-Littlewood inequalities in the present setting of $H^{\vec{p}}_A(\mathbb{R}^n)$.

• 대한물리의학회지
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• 제6권2호
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• pp.215-223
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• 2011

Purpose: The purpose of this study was to determine the effect of leg muscle activation by applying proprioceptive neuromuscular facilitation (PNF) arm patterns to unilateral upper extremities under the condition of both open and closed kinetic chains in a seated position. Methods: Twenty-two healthy subjects participated in this study. Four PNF patterns were applied to each subject's unilateral upper extremity. EMG data were collected from the vastus medialis, biceps femoris, tibialis anterior and gastrocnemius. The measured EMG data were digitized and processed to root mean square (RMS) and expressed as percentage maximal voluntary isometric contraction (%MVIC). The data were analyzed using two-way analysis of variance (ANOVA) with repeated measures to determine the statistical significance. Results: The results of this study were summarized as follows: Firstly, in comparison to muscle activation of the biceps femoris, there was a significant increase in the D2 flexion pattern when it was compared with D2 extension pattern and when it was compared with D1 flexion pattern (p<.05). Secondly, there was a significant increase in the muscle activation of the vastus medialis and tibialis anterior with a closed kinetic chain rather than an open kinetic chain (p<.05). Conclusion: In conclusion, in order to increase muscle activation of the biceps femoris, the D2 flexion pattern can be applied, regardless of kinetic chain. In addition, in order to increase muscle activation of the vastus medialis and tibialis anterior, four arm patterns can be applied with a closed kinetic chain.

• 대한화학회지
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• 제40권9호
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• pp.630-634
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• 1996

양배추 포스포리파제 D의 기질특이성을 조사하기 위해 아실 사슬길이가 틀린 코린 인지질을 사용하여 그 반응성을 검토하였다. 선택한 아실 사슬은 포화지방산 $C_8:0,\;C_{12}:0,\;C_{16}:0,\;C_{20}:0$이었다. 이들 인지질들의 반응성은 계면활성제 Sodium dodecyl sulfate의 농도에 따라 큰 영향을 받았으며, 아실 사슬길이가 길어짐에 따라 최적 PC : SDS의 농도비는 1:1.4, 1:2.2, 1:2.5, 1:3.6으로 나타났다. 이와 함께, 효소의 최적활성을 나타내는 온도도 길이가 길어짐에 따라 20$^{\circ}C$, 30$^{\circ}C$, 35$^{\circ}C$, 45$^{\circ}C$로 크게 변화하였다. 이와는 달리 최적 pH와 $Ca^{2+}$농도는 사슬길이에 따라 큰 영향을 받지 않았다. $V_{max}$ 값은 아실 사슬의 기질이 가장 커 가수분해가 잘 일어남을 보여주었으며 사슬길이가 길어질수록 반응속도는 감소하였다.

• Journal of Microbiology
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• 제43권4호
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• pp.375-380
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• 2005

Autonomous ultradian metabolic oscillation (T$\simeq$50 min) was detected in an aerobic chemostat culture of Saccharomyces cerevisiae. A pulse injection of GSH (a reduced form of glutathione) into the culture induced a perturbation in metabolic oscillation, with respiratory inhibition caused by $H_2S$ burst pro-duction. As the production of $H_2S$ in the culture was controlled by different amino acids, we attempted to characterize the effects of GSH on amino acid metabolism, particularly with regard to branched chain and sulfur-containing amino acids. During stable metabolic oscillation, concentrations of intra-cellular glutamate, aspartate, threonine, valine, leucine, isoleucine, and cysteine were observed to oscil-late with the same periods of dissolved $O_2$ oscillation, although the oscillation amplitudes and maximal phases were shown to differ. The methionine concentration was stably maintained at 0.05 mM. When GSH (100 $\mu$M) was injected into the culture, cellular levels of branched chain amino acids increased dramatically with continuous $H_2S$production, whereas the cysteine and methionine concentrations were noticeably reduced. These results indicate that GSH-dependent perturbation occurs as the result of the promotion of branched chain amino acid synthesis and an attenuation of cysteine and methionine synthesis, both of which activate the generation of $H_2S$. In a low sulfate medium containing 2.5 mM sulfate, the GSH injections did not result in perturbations of dissolved $O_2$ NAD(P)H redox oscillations without burst $H_2S$ production. This suggests that GSH-dependent perturbation is intimately linked with the metabolism of branched-chain amino acids and $H_2S$ generation, rather than with direct GSH-GSSG redox control.

• 한국생물공학회:학술대회논문집
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• 한국생물공학회 2003년도 생물공학의 동향(XII)
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• pp.34-38
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• 2003

For the production of $B^{30}-homoserine$ insulin analog as a novel anti-diabetic drug, the fermentative study was attempted for the maximal gene expression of HTS-fused $B^{30}-homoserine$ insulin precursor in the recombinant Escherichia coli cells. In a batch fermentation, the maximal production of insulin precursor as much as 38.95 mg/L-h, which occupied more than 12.8% of total cell protein. was achieved when the gene expression was induced by 0.5 mM IPTG at the middle logarithmic growth phase. The HTS-fused $B^{30}-homoserine$ insulin precursor was recovered from a batch culture through the processes of cell harvest, collection of insoluble fraction after sonication and purification by nickel affinity column chromatography. The isolated insulin precursor was 14 mg/L with a recovery yield of 35.9% of expressed gene product. The insulin A and B chain mixture was recovered after the insulin precursor was subjected to CNBr cleavage and purified by nickel affinity column chromatography. The isolated insulin chains were then sulfitolyzed with sodium thiosulfat and sodium tetrathionate, and reconstituted to insulin analog with ${\beta}-mercaptoethanol$, followed by purification with CM-Sepharose C-25 column chromatography.

• 한국군사과학기술학회지
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• 제14권3호
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• pp.458-466
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• 2011

In war time, minimizing the logistics response time for supporting military operations is strongly needed. In this paper, i propose the mathematical formulation for minimizing the maximal acquisition completion time in wartime or during a state of emergency. The main structure of this formulation is based on the traveling purchaser problem (TPP), which is a generalized form of the well-known traveling salesman problem (TSP). In the case of the general TPP, an objective function is to minimize the sum of the traveling cost and the purchase cost. However, in this study, the objective function is to minimize the traveling cost only. That's why it's more important to minimize the traveling cost (time or distance) than the purchase cost in wartime or in a state of emergency. I generate a specific instance and find out the optimal solution of this instance by using ILOG OPL STUDIO (CPLEX version 11.1).

• 대한치과교정학회지
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• 제48권6호
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• pp.384-394
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• 2018

Objective: This study was performed to investigate an appropriate degree of prestretch for orthodontic synthetic elastomeric chains focusing on time-dependent viscoelastic properties. Methods: Orthodontic synthetic elastomeric chains of two brands were prestretched to 50, 100, 150, and 200% of the original length in one and three cycles, and the hysteresis areas of the obtained stress-strain curves were determined. Acrylic plates were employed to maintain constant strain during the experiment. A total of 180 samples were classified into nine groups according to brand, and their stresses and permanent deformations were measured immediately after prestretch (0 hour), after 1 hour and 24 hours, and after 1, 2, 3, 4, 5, 6, 7, and 8 weeks. The relationship between stress relaxation and permanent deformation was investigated for various degrees of prestretch, and the estimated stress resulting from tooth movement was calculated. Results: The degree of prestretch and the stress relaxation ratio exhibited a strong negative correlation, whereas no correlation was found between the degree of prestretch and the average normalized permanent strain. The maximal estimated stress was observed when prestretch was performed in three cycles to 200% of the original length. Conclusions: Although prestretch benefited residual stress, it did not exhibit negative effects such as permanent deformation. The maximal estimated stress was observed at the maximal prestretch, but the difference between prestretch and control groups decreased with time. In general, higher residual stresses were observed for product B than for product A, but this difference was not clinically significant.

• ETRI Journal
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• 제34권1호
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• pp.24-34
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• 2012

In this paper, the directional carrier sense multiple access/collision avoidance (CSMA/CA) protocol in the immediate acknowledgement mode for IEEE 802.15.3c is analyzed under saturation environments. For the analysis, a sensing region and an exclusive region with a directional antenna are computed probabilistically and a Markov chain model in which the features of IEEE 802.15.3c and the effects of using directional antennas are incorporated is analyzed. An algorithm to find the maximal number of concurrently transmittable frames is proposed. The system throughput and the average transmission delay are obtained in closed forms. The numerical results show the impact of directional antennas on the CSMA/CA media access control (MAC) protocol. For instance, the throughput with a small beamwidth of antenna is more than ten times larger than that for an omnidirectional antenna. The overall analysis is verified by a simulation. The obtained results will be helpful in developing an MAC protocol for enhancing the performance of mmWave wireless personal area networks.

• Journal of Information Processing Systems
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• 제10권4호
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• pp.602-617
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• 2014

The performance of a cognitive radio network (CRN) solely depends on how precisely the secondary users can sense the presence or absence of primary users. The incorporation of a spatial false alarm makes deriving the probability of a correct decision a cumbersome task. Previous literature performed this task for the case of a received signal under a Normal probability density function case. In this paper we enhance the previous work, including the impact of carrier frequency, the gain of antennas on both sides, and antenna heights so as to observe the robustness against noise and interference and to make the correct decision of detection. Three small scale fading channels: Rayleigh, Normal, and Weibull were considered to get the real scenario of a CRN in an urban area. The incorporation of a maximal-ratio combining and selection combing with a variation of the number of received antennas have also been studied in order to achieve the correct decision of spectral sensing, so as to serve the cognitive users. Finally, we applied the above concept to a traffic model of the CRN, which we based on a two-dimensional state transition chain.