• Title/Summary/Keyword: material medica

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Studies on the Ginseng Polypeptide-Decreasing Blood Sugar and Hapatic Glycogen. (인삼 폴리펩티드 연구-혈당 및 간 글리코겐 저하작용)

  • Jin Zhang;Hongying Zhang;Wenyun Du;Dawei Wang;Benxiang Wang;Ming Yang;Yulian Jin;Zhiyong Cui;Yan Wang
    • Journal of Ginseng Research
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    • v.14 no.2
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    • pp.285-290
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    • 1990
  • Ando et al found the root of Ginseng contained an active peptide which had anti-lipolysis funrtion when they studied effective components of Ginseng to cure diabetes mellitus in 1980. In recent years we were making lots of the researches on the Ginseng polypeptide. We obtained a 14 peptide which could decrease levels of blood sugar and hepatic glycogen. However, amino acid composition of the peptide differs from one reported by Ando et al. The results of its purification, structure and functure and function were reported in this paper.

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A Study on Symbols of the Book of Changes Described in the Compendium of Materia Medica (『본초강목(本草綱目)』을 통해 본 『주역(周易)』의 물상(物象)에 대한 고찰)

  • Kim, Minjeong;Kang, Yeonseok
    • The Journal of Korean Medical History
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    • v.31 no.1
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    • pp.135-147
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    • 2018
  • Analyzing the Book of Changes, researchers noted that animals and plants utilized as symbols in the Book of Changes were later used as medicinals in East Asian medicine. They found 24 animals and plants utilized as symbols in the Book of Changes; specifically in six statements on the hexagrams and 53 statements on the lines. The animal and plant symbols in 59 statements are more clearly interpreted with the descriptions in the Compendium of Materia Medica. Eleven plants referenced in the Book of Changes were written with their nicknames, causing confusion to the researchers of later times. Using the Compendium of Materia Medica however, these plants can be identified. Livestock were mentioned 34 times among the 59 statements, with horse and cattle being the most often at eight times, each. They are subdivided according to their sex and color. The writers of the Book of Changes constructed an elaborate symbol system with the animals that are familiar to people, and which, through this research, has been decoded through cross references to the Compendium of Material Medica.

Comparative Study of Qi-sensational Movement of 'Hanalmomjit' and the Properties of Materia Medica ('한알몸짓'의 기감동작(氣感動作)과 한약의 약성(藥性)에 대한 비교 연구)

  • Lee, Jeong-Won;Shin, Soon-Shik;Kim, Gyeong-Cheol
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.19 no.2
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    • pp.358-362
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    • 2005
  • Directional words like 'ascending(升, sheng)', 'descending(降, jiang)', 'floating(浮, fu)', 'sinking(沈, chen) are technical terminologies of Oriental Medicine to express the directions of material medica functioning-at the phase of Qi-superiorly, inferiorly, exteriorly, and interiorly in human body, and are constituting one of the major principles in prescribing medicines. Lacking the objective methodology to measure or, at least determine Qi, However, we can not expect to secure meaningful data to verify those directional terms. This problematic situation caused chaotic discrepancy between theory and practice of Oriental Medicine. Thus, adopting the method of dynamic meditation 'Hanalmomjit' of Lux Vitae meditation society, by which various state of Qi-sensational movements can be expressed, we compared its moves with the directional terms of traditional canons in Oriental Medicine. In this thesis, the experiment of expressing materia medica via 'Hanalmomjit' is resulted out and compared with the terms, confirmed to have a certain meaningfulness. The new method showed these results below: Herba Menthae, described to have the disposition of ascending and floating, showed 60% of ascending movements in 'Hanalmomjit' experiment. Radix Rehmanniae Praeparata, described to have the disposition of descending and sinking, showed 50% of descending movements. Radix Glycyrrhizae, described to have plain disposition, showed 60% of central movements. Rhizoma Atractylodis and Pericarpium Citri Reticulatae, described to have the disposition of ascending and floating, showed also ascending movements. Cortex Magnoliae Officinalis, described to have the disposition of descending and sinking, showed also descending movements. In conclusion, qi-sensational movement of 'Hanalmomjit' for materia medica showed sufficient relations described in classics, proving itself to be useful method for objective demonstration of material medica.

Interleukin-5 Inhibition Assay of the Oriental Materia Medica Treatment by High Through Screening on the Splenocyte of Mouse (High through screening(HTS)를 이용한 백서(白鼠)의 비장세포(脾臟細胞)에서의 IL-5 분비 조절 한약물(韓藥物) Screening)

  • Park, Dong-Hee;Rhee, Hyung-Koo;Jung, Sung-Ki;Jung, Hee-Jae
    • The Journal of Internal Korean Medicine
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    • v.27 no.2
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    • pp.394-406
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    • 2006
  • Backgrounds and Objectives: Asthma is considered to be an inflammatory disease characterized by airway hyperresponsiveness and Pulmonary eosinophilia. And it is known the structure and function of IL-5, its receptor and the mechnism IL-5 triggered eosinophil accumulation and inflammaion of the airways. At this point of view, we assume which oriental materia medics can the splenocyte inhibit from secreting the IL-S in vitro. Material and Methosds: We used the splenocyte of mouse 8 weeks after its birth, and then cnltivated those into the 2 experimental groups and control group for 48 hours. The culture medium of experimental groups were made of $1{\mu}g/ml,\;10{\mu}g/ml$, oriental materia medics, representative. And the culture media of control group was given no oriental materia medica. Then, we assayed the quantity of cytokine-expression by the Sandwich ELISA. The quantifies of cytokine-expression of the experimental groups were compared with that of the control group which was standardized These method were used for the all of oriental materia medica treated. Results: In this study, we demonstrated that 12 oriental materia medica that inhibit the splenocyte from secreting the IL-5 in both $1{\mu}g/ml,\;and\;10{\mu}g/ml$ culture media. Those were Equiseti Herbs, Sophorae Subprostratae Radix, Moutan Radicis Cortex. Trichosanthis Radix, Buddleiae Flos. Cyperi Rhizoma. Benincasae Semen, Armeniacae Semen. Zedoariae Rhizoma, Astragali Semen, Dolichoris Semen. Lilii Bulbus, Asparagi Radix, Atractylodes Rhizoma White, Polygonati Officinallis Rhizoma. Conculusions: These findinga indicate that some oriental materia medica, specially Antipyretics, Herbs for Resolving Phlegm, Relieving Cough and Calming Wheezing and Herbs for Tonifring and Invigorating effects inhibit the splenocyte from secreting the IL-5. And further study experimented in vivo is needed for treating IL-5-driven inflammatory disease including asthma.

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Comparative Study of Terminology for Identification of the Chinese Herbal Materia Medica (초본류 한약재 감별을 위한 용어의 비교연구)

  • Shin, Yong-Wook
    • The Korea Journal of Herbology
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    • v.29 no.3
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    • pp.43-50
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    • 2014
  • Objectives : To investigate terminology of Herbal drug discrimination commonly used in China, and it was translated into Korean. It also has been modified to fit the circumstances of the Korean for easier understand for Korean student. Methods : First,Terminology for Identification of the Chinese Herbal Materia Medica (TICHMM) was classified by the appearance, cut surface, material, processing and storage of Herb. Chinese commentary of TICHMM was translated into Korean. Comparative Study was performed based on the Pharmacopoeia of Korea and China. Depending on the meaning of the word, TICHMM was modified to revised Korean expression or remain chinese expression or suggest new Korean expression Result : In the 28 TICHMM terms that describes the shape properties of herbal medicine, 5 was remained in Chinese expression, 22 was modified to revised Korean expression and 1 was suggested in new Korean expression. 8 terms that describes the Section properties of herbal medicine, 6 was modified to revised Korean expression and 2 was suggested in new Korean expression. 3 terms that describes the Material properties of herbal medicine, 1 was remained in Chinese expression, 2 was modified to revised Korean expression. 3 terms that describes the processing and storage properties of herbal medicine, 2 was modified to revised Korean expression and 1 was suggested in new Korean expression. Conclusion : By comparative Study of TICHMM, commonly used in China, it will contribute new guideline on the Visual Examination of Herbal Medicine for Korean student.

Knowledge on Fish in the Imwon-Gyeongje-Ji from a Korean Medical Perspective - A Comparative Study with the Dongui-bogam - (『림원경제지(林園經濟志)』 어류지식의 한의학적 고찰 - 『동의보감(東醫寶鑑)』과의 비교를 중심으로 -)

  • JEON, Jongwook
    • Journal of Korean Medical classics
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    • v.35 no.3
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    • pp.71-90
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    • 2022
  • Objectives : This paper summarizes contents on fish in the Injeji and Jeoneo-Ji parts in the Imwon-Gyeongje-Ji and compares them with those in the Dong-uibogam from a Korean Medical perspective. Methods : Most of the knowledge of fish in the Imwon-Gyeongje-Ji is based on preceding material medica studies such as the Dongui-bogam in Joseon, the Bencao-gangmu in China, and the Hwahan Samjaedohoe in Japan. The influential relationships and the process of change among these knowledge information were examined within the context of each literature's development or through identifiable changes in knowledge on each particular kind of fish. Results & Conclusions : In the Imwon-Gyeongje-Ji, the consisting 16 parts are organically connected, sometimes functioning as cross-references. In particular, the medical contents on the efficacy of fish for treating disease is closely linked to contents on fish ecology and environment as written in the Jeoneo-Ji, which deals with the field of living things. On the more detailed knowledge on about 30 kinds of fish, one could grasp the formation process and changes of East Asian traditional knowledge on fishkind among historical study of influential Chinese texts, new stimulation and methodology through Japanese literature on natural history, and dynamic processes of inheriting and selectively accepting traditional knowledge of Joseon.

Evaluation of some indigenous plant extracts for antiimplantation activity in albino rats

  • Pateel, Mallikarjun;Sharanabasappa, Sharanabasappa;Malashetty, Viajykumar B;Patil, Saraswati B;A, Veeranagoud
    • Advances in Traditional Medicine
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    • v.5 no.4
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    • pp.347-351
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    • 2005
  • In the present investigation twelve indigenous medicinal plants have been screened for their antiimplantation activity in albino rats. The plant material was subjected for soxhlation successively and separately from non-polar solvents to polar solvents i.e., petroleum ether benzene and ethanol. Out of these three extracts the petroleum ether extract of seeds of Citrus medica, aerial part of Oxalis corniculata and Tinospora cardifolia have showed maximum antiimplantation activity. Ethanol extract of leaves of Cardiospermum helicacabum, roots of Echinops echinatus, leaves of Melia azedarach, seeds of Momordica charantia and bark of Terminalia bellirica have shown maximum antiimplantation activity amongst the three extracts of each plant material screened. Though all the three extracts of seeds of Annona squamosa and leaves of Zizyphus jujube screened for antiimplantation activity, no extract has showed any loss in implantation. The details of the results obtained are discussed.

A Bibliographical Study on "Bonchogyeongjipju(本草經集注)" ("본초경집주(本草經集注)"에 대한 서지학적(書誌學的) 연구)

  • Kim, Yong-Joo;Baik, You-Sang;Jang, Wu-Chang;Jeong, Chang-Hyeon
    • Journal of Korean Medical classics
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    • v.23 no.2
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    • pp.191-203
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    • 2010
  • "Bonchogyeongjipju(本草經集注)" is a pharmacological classic published in the Southern and Northern Dynasties(南北朝時代, 420-589 A.D.) in China by Dohonggyeong(陶弘景, 456-536 A.D.). In "Bonchogyeongjipju(本草經集注)", Dohonggyeong(陶弘景) edited "Sinnongbonchogyeong(神農本草經)", the earliest classical text about material medica containing notes for 365 drugs, by adding another 365 drugs and further information from "Myeong-uibyeollok(名醫別錄)" and writing extended commentaries on them. His commentaries include changes in the geographical distribution, identification of varieties and other various special characteristics. The original text had gradually disappeared after other pharmacological classics were published such as "Sinsuboncho(新修本草)", in Dang Dynasty(唐代), "Gyeongsajeungryubigeupboncho(經史證類備急本草)" in Song Dynasty(宋代). All of these books were based on "Bonchogyeongjipju(本草經集注)", so the original text can be seen indirectly through these later sources. In the early 1900's, a transcribed manuscript of the preface "Bonchogyeongjipju(本草經集注)" was found almost wholly preserved except the first three lines, in the Makgo(莫高) cave of Donhwang(敦煌). Broken strips of transcribed "Bonchogyeongjipju(本草經集注)" have also been excavated in Turfan[吐魯番], which shows its original form written in red and black ink. Mayanagi Makoto[眞柳誠] researched on Donhwang(敦煌) and Turfan[吐魯番] editions, ascertained their existence and explained their bibliographical and historical facts. Sangjigyun(尙志鈞) restored "Bonchogyeongjipju(本草經集注)" based on other related sources such as Donhwang(敦煌) and Turfan[吐魯番] editions. " Bonchogyeongjipju(本草經集注)" can be said as the locus classicus(典範) of herbal medicine, that is most of the following materia medica was based on it. It makes it possible to pass down "Sinnongbonchogyeong(神農本草經)" to posterity and provide a foundation for herbal medical development.

Quality Control and Evaluation of Platycodon grandiflorum: Implications for Future Management

  • Xu, Bao-Jun;Zheng, Yi-Nan;Sung, Chang-Keun
    • Natural Product Sciences
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    • v.10 no.4
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    • pp.141-151
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    • 2004
  • Platycodi Radix, as one of the most important traditional oriental materia medica, is utilized frequently in clinical practice and dietary in China, Korea, and Japan. To evaluate definitely the quality of Platycodi Radix, and provide scientific data for commodity circulation, new product development and clinical application of Platycodi Radix, we summarized its medical history, application status, chemical compositions, bioactivities, cultivation, international circulation, quality evaluation, dosage and safety, and brought forward some constructive suggestions on further establishment of international criteria for quality control of Platycodon grandiflorum.