• Title/Summary/Keyword: market stability

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Development and validation of an LC-MS/MS method for the simultaneous analysis of 26 anti-diabetic drugs in adulterated dietary supplements and its application to a forensic sample

  • Kim, Nam Sook;Yoo, Geum Joo;Kim, Kyu Yeon;Lee, Ji Hyun;Park, Sung-Kwan;Baek, Sun Young;Kang, Hoil
    • Analytical Science and Technology
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    • v.32 no.2
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    • pp.35-47
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    • 2019
  • In this study, high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) was employed to detect 26 antidiabetic compounds in adulterated dietary supplements using a simple, selective method. The work presented herein may help prevent incidents related to food adulteration and restrict the illegal food market. The best separation was obtained on a Shiseido Capcell Pak(R) C18 MG-II ($2.0mm{\times}100mm$, $3{\mu}m$), which improved the peak shape and MS detection sensitivity of the target compounds. A gradient elution system composed of 0.1 % (v/v) formic acid in distilled water and methanol at a flow rate of 0.3 mL/min for 18 min was utilized. A triple quadrupole mass spectrometer with an electrospray ionization source operated in the positive or negative mode was employed as the detector. The developed method was validated as follows: specificity was confirmed in the multiple reaction monitoring mode using the precursor and product ion pairs. For solid samples, LOD ranged from 0.16 to 20.00 ng/mL and LOQ ranged from 0.50 to 60.00 ng/mL, and for liquid samples, LOD ranged from 0.16 to 20.00 ng/mL and LOQ ranged from 0.50 to 60.00 ng/mL. Satisfactory linearity was obtained from calibration curves, with $R^2$ > 0.99. Both intra and inter-day precision were less than 13.19 %. Accuracies ranged from 80.69 to 118.81 % (intra/inter-day), with a stability of less than 14.88 %. Mean recovery was found to be 80.6-119.0 % and less than 13.4 % RSD. Using the validated method, glibenclamide and pioglitazone were simultaneously determined in one capsule at concentrations of 1.52 and 0.53 mg (per capsule), respectively.

Analysis of the Behavior Characteristics of Pile Foundations Responding to Ground Deformation (지반 변형 대응형 말뚝 기초의 거동 특성 분석)

  • Lee, Junwon;Shin, Sehee;Lee, Haklin;Kim, Dongwook;Lee, Kicheol
    • Journal of the Korean Geosynthetics Society
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    • v.19 no.4
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    • pp.21-32
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    • 2020
  • As the global large-scale infrastructure construction market expands, the construction of civil engineering structures in extreme environments such as cold or hot regions is being planned or constructed. Accordingly, the construction of the pile foundation is essential to secure the bearing capacity of the upper structure, but there is a concern about loss of stability and function of the pile foundation due to the possibility of ground deformation in extreme cold and hot regions. Therefore, in this study, a new type of pile foundation is developed to respond with the deformation of the ground, and the ground deformation that can occur in extreme cold and hot region is largely divided into heaving and settlement. The new type of pile foundation is a form in which a cylinder capable of shrinkage and expansion is inserted inside the steel pipe pile, and the effect of the cylinder during the heaving and settlement process was analyzed numerically. As a result of the numerical analysis, the ground heaving caused excessive tensile stress of the pile, and the expansion condition of the cylinder shared the tensile stress acting on the pile and reduced the axial stress acting on the pile. Ground settlement increased the compressive stress of the pile due to the occurrence of negative skin friction. The cylinder must be positioned below the neutral point and behave in shrinkage for optimum efficiency. However, the amount and location of shrinkage and expansion of cylinder must comply with the allowable displacement range of the upper structure. It is judged that the design needs to be considered.

Housing Choice Determinants of the Youth and Newlyweds Households: A Case Study of Incheon (청년·신혼부부의 주거선택요인에 관한 연구: 인천시를 중심으로)

  • Key, Yunhwan
    • Land and Housing Review
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    • v.13 no.4
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    • pp.13-26
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    • 2022
  • This study analyzes housing choice determinants of the youth and newlyweds households by using housing survey data in Incheon. A multinomial logit model is employed for analysis with the following variables: housing characteristics, housing market characteristics, and residential and neighborhood environment characteristics. The findings from the analysis are as follows. First, for the continued residence of the youth, the important factors were the relief assistance of housing maintenance costs. For the newlyweds, the important factors were the quality improvement of residential environments to ensure residential stability. Second, the housing choice factors to attract the youth were residential support for rent, maintenance costs, and relocation, and the improvements of residential environments such as security, noise levels, and medical facilities. For the newlyweds, the important factors were housing loan assistance for a home purchase or a cheonsei deposit and residential quality improvements for air pollution and parking facilities. Third, the youth were likely to move out due to high rental costs, and the newlyweds were likely to move out for the purchase of a new apartment or higher-quality housing.

Development of Ship Valuation Model by Neural Network (신경망기법을 활용한 선박 가치평가 모델 개발)

  • Kim, Donggyun;Choi, Jung-Suk
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.27 no.1
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    • pp.13-21
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    • 2021
  • The purpose of this study is to develop the ship valuation model by utilizing the neural network model. The target of the valuation was secondhand VLCC. The variables were set as major factors inducing changes in the value of ship through prior research, and the corresponding data were collected on a monthly basis from January 2000 to August 2020. To determine the stability of subsequent variables, a multi-collinearity test was carried out and finally the research structure was designed by selecting six independent variables and one dependent variable. Based on this structure, a total of nine simulation models were designed using linear regression, neural network regression, and random forest algorithm. In addition, the accuracy of the evaluation results are improved through comparative verification between each model. As a result of the evaluation, it was found that the most accurate when the neural network regression model, which consist of a hidden layer composed of two layers, was simulated through comparison with actual VLCC values. The possible implications of this study first, creative research in terms of applying neural network model to ship valuation; this deviates from the existing formalized evaluation techniques. Second, the objectivity of research results was enhanced from a dynamic perspective by analyzing and predicting the factors of changes in the shipping. market.

Breeding a new variety of white Hypsizygus marmoreus 'Baekmaru' with excellent cultivation stability and storability (재배적 안정성과 저장성이 우수한 백색 느티만가닥버섯 신품종 '백마루' 육성)

  • Oh, Youn-Lee;Kim, Minseek;Jang, Kab-Yeul;Oh, Min Ji;Im, Ji-Hoon;Lee, Jong-Won
    • Journal of Mushroom
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    • v.20 no.3
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    • pp.153-162
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    • 2022
  • The purpose of this study was to breed a variety of stable productivity and high storage characteristics of white Hypsizygus marmoreus, which has high demand at domestic and global market due to a low bitter taste and the preference for white species. Accordingly, 'Baekmaru' was bred by hybridizing brown and white cap color species and backcrossing with white species. The 'Baekmaru' variety was bred by crossbreeding the brown and white species and backcrossing the white species. Through repeated cultivation of 'Baekmaru', a variety with a low contamination rate was selected when culturing the spawn for stable cultivation. As a results of demonstration test, the yield of 'Baekmaru' was 14% higher than that of the commercial variety. In addition, among the fruiting body characteristics of 'Baekmaru', diameter and thickness of the pileus were 16.43±15.27mm and 6.46±0.58mm, which were slightly higher than the commercial variety, and the hardness was 2.69±0.89N for the pileus and 3.09±0.89N for the stipe. The shelf life showed less change in thickness and color of pileus compared to commercial variety. The hardness of pileus of 'Baekmaru' was maintained in the range of 3.5 to 4.0N in the 4℃ and 4℃ and 20℃ mixed treatment until 30 days of storage, and was higher than that of the commercial variety. Therefore, it was suggested to be excellent in storability.

May 24 Measures and Future North Korea Policy (5.24 대북조치와 향후 대북정책 과제)

  • Kim, Tae-Woo
    • Strategy21
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    • s.34
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    • pp.128-148
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    • 2014
  • In south Korea, the so-called 'conservative-liberal' rivalry over the assessment of the government's North Korean policies is seen to be impeding the road to right policy choices. For example, the liberals accused former President Lee Myung-bak's hardline policy of provoking Pyongyang and leading to a deterioration of inter-Korean relations, while the conservatives appreciated it for helping nurture mutually beneficial inter-Korean relations in the longer term by compelling North Korea to observe international norms. However, such debate over the vices and virtues of Seoul's North Korea policies is hardly meaningful as the measuring sticks used by the liberals and the conservatives are entirely different matters. The two major goals South Korea must pursue with its North Korean policies should be 'peaceful management of division' and 'change in North Korea'. The former is related to maintaining stability within South Korea and promoting co-prosperity with North Korea. For this, the nation needs to engage, encompass and assist the Pyongyang regime. The second goal is also necessary since South Korea, as a divided nation, must seek a unified Korea under the system of democracy and market economies by bringing change in North Korea. For this, South Korea needs powerful leverages with which it can persuade and coerce the North. This means that the nation is destined to simultaneously chase the above-mentioned two goals, while also both recognizing and negating the legitimacy of the North Korean regime. This situation necessitates Seoul to apply flexibility in reconciling with Pyongyang while applying firm principles to sever the vicious circle involving the North's military provocations. The May 25 Measures, which banned trade and economic cooperation with the North except those related to humanitarian assistance, were taken as sanctions against Pyongyang for sinking the South Korean corvette Chonan in March 2010. The Measures were taken by the Seoul government immediately after a multinational investigation team discovered evidence confirming that the South Korean naval ship had been torpedoed by a midget North Korean submarine. Naturally, the May 24 Measures have since then become a major stumbling block in inter-Korean exchange, prompting opposition politicians and concerned entrepreneurs to demand Seoul to unilaterally lift the Measures. Given the significant damages the Measures have inflicted on inter-Korean economic relations, removing them remains as homework for both Koreas. However, the Measures pertains to the 'principles on national security' the Seoul government must adhere to under all circumstances. This is why North Korea's apology and promises not to repeat similar provocations must come first. For now, South Korea has no alternative but to let North Korea solve the problems it has created. South Korea's role is to help the North do so.

Design of Ship-type Floating LiDAR Buoy System for Wind Resource Measurement inthe Korean West Sea and Numerical Analysis of Stability Assessment of Mooring System (서해안 해상풍력단지 풍황관측용 부유식 라이다 운영을 위한 선박형 부표식 설계 및 계류 시스템의 수치 해석적 안정성 평가)

  • Yong-Soo, Gang;Jong-Kyu, Kim;Baek-Bum, Lee;Su-In, Yang;Jong-Wook, Kim
    • Journal of Navigation and Port Research
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    • v.46 no.6
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    • pp.483-490
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    • 2022
  • Floating LiDAR is a system that provides a new paradigm for wind condition observation, which is essential when creating an offshore wind farm. As it can save time and money, minimize environmental impact, and even reduce backlash from local communities, it is emerging as the industry standard. However, the design and verification of a stable platform is very important, as disturbance factors caused by fluctuations of the buoy affect the reliability of observation data. In Korea, due to the nation's late entry into the technology, a number of foreign equipment manufacturers are dominating the domestic market. The west coast of Korea is a shallow sea environment with a very large tidal difference, so strong currents repeatedly appear depending on the region, and waves of strong energy that differ by season are formed. This paper conducted a study examining buoys suitable for LiDAR operation in the waters of Korea, which have such complex environmental characteristics. In this paper, we will introduce examples of optimized design and verification of ship-type buoys, which were applied first, and derive important concepts that will serve as the basis for the development of various platforms in the future.

Deep Learning-based UWB Distance Measurement for Wireless Power Transfer of Autonomous Vehicles in Indoor Environment (실내환경에서의 자율주행차 무선 전력 전송을 위한 딥러닝 기반 UWB 거리 측정)

  • Hye-Jung Kim;Yong-ju Park;Seung-Jae Han
    • KIPS Transactions on Computer and Communication Systems
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    • v.13 no.1
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    • pp.21-30
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    • 2024
  • As the self-driving car market continues to grow, the need for charging infrastructure is growing. However, in the case of a wireless charging system, stability issues are being raised because it requires a large amount of power compared with conventional wired charging. SAE J2954 is a standard for building autonomous vehicle wireless charging infrastructure, and the standard defines a communication method between a vehicle and a power transmission system. SAE J2954 recommends using physical media such as Wi-Fi, Bluetooth, and UWB as a wireless charging communication method for autonomous vehicles to enable communication between the vehicle and the charging pad. In particular, UWB is a suitable solution for indoor and outdoor charging environments because it exhibits robust communication capabilities in indoor environments and is not sensitive to interference. In this standard, the process for building a wireless power transmission system is divided into several stages from the start to the completion of charging. In this study, UWB technology is used as a means of fine alignment, a process in the wireless power transmission system. To determine the applicability to an actual autonomous vehicle wireless power transmission system, experiments were conducted based on distance, and the distance information was collected from UWB. To improve the accuracy of the distance data obtained from UWB, we propose a Single Model and Multi Model that apply machine learning and deep learning techniques to the collected data through a three-step preprocessing process.

A study of Predicting International Gasoline Prices based on Multiple Linear Regression with Economic Indicators (경제지표를 활용한 다중선형회귀 모델 기반 국제 휘발유 가격 예측)

  • Myeongeun Han;Jiyeon Kim;Hyunhee Lee;Sein Kim;Minseo Park
    • The Journal of the Convergence on Culture Technology
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    • v.10 no.1
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    • pp.159-164
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    • 2024
  • The domestic petroleum market is highly sensitive to changes in international oil prices. So, it is important to identify and respond to those changes. In particular, it is necessary to clearly understand the factors causing the price fluctuations of gasoline, which exhibits high consumption. International gasoline prices are influenced by global factors such as gasoline supplies, geopolitical events, and fluctuations in the U.S. dollar. However, previous studies have only focused on gasoline supplies. In this study, we explore the causal relationship between economic indicators and international gasoline prices using various machine learning-based regression models. First, we collect data on various global economic indicators. Second, we perform data preprocessing. Third, we model using Multiple linear regression, Ridge regression, and Lasso(Least Absolute Shrinkage and Selection Operator) regression. The multiple linear regression model showed the highest accuracy at 96.73% in test sets. As a result, Our Multiple linear regression model showed the highest accuracy at 96.73% in test sets. We will expect that our proposed model will be helpful for domestic economic stability and energy policy decisions.

Overview of the Korean Marine Industry and VPP Analysis of a 28ft Sailing Yacht (대한민국의 해양 레저 시장 및 28ft급 세일요트의 VPP 성능해석 연구)

  • Yeongmin Park;Hoyun Jang;Minsu Kang
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.30 no.4
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    • pp.365-372
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    • 2024
  • The South Korean marine industry is emerging as a significant market, driven by the growing popularity of various water leisure activities, including sailing. This trend suggests a rising demand for sailing yachts. Consequently, since 2022, the design and development of a 28ft sailing yacht have been ongoing, supported by the government and the Ministry of Oceans and Fisheries, to promote yachting culture in South Korea. The Velocity Prediction Program (VPP) analysis was conducted using WinDesign during the preliminary design stage to evaluate performance and determine design parameters. The hydrodynamic model used for this vessel is based on regression methods developed from years of experience in naval architecture and yacht research at the Wolfson Unit, providing reliable estimates for most modern yachts. However, owing to the lack of specific hydrodynamic data from towing tank tests or CFD numerical analysis, verification of the hydrodynamic model has faced some challenges. Additionally, an incomplete weight estimate resulted in variable VCG values, potentially affecting stability and overall performance. The optimal boat speed for this vessel was determined at true wind speeds (TWS) of 4, 8, 12, 16, and 20 knots, using both the jib (up to 120° TWA) and the spinnaker (from 80° TWA). The optimized speed of the yacht was found to be comparable to that of international similar-class yachts.