• Toxicological Research
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• v.9 no.2
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• pp.207-215
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• 1993

Lead is an environmental toxicant that causes a marked deficit in cognative development in infants and children. Damage to the hippocampus has been linked to the lead-induced deficit in the learning process. The present study examined the effects of lead on the development of hippocampal neurons in vitro. Hippocampal neurons were incubated with various concentrations in lead acetate (1nM to 30 nM) for 72 hrs from 4 h after plating, and the percentage of living neurons bearing neurites, neurite outgrowth and migration of multipolar neurons in culture were determined.

• Journal of Digital Contents Society
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• v.15 no.3
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• pp.357-363
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• 2014

In this paper, we propose a new audio forensic marking system for protecting the copyright of the Internet-based music streaming services. In the proposed method, in order to guarantee the QoS of the streaming service, high speed, and generates a forensic mark inserted MP3 file. We make pre-marking process and generate a new forensic marked MP3 file, a combination of the pre-marked MP3 frame, the inserted user information. Experimental results show that the proposed method satisfactory results robustness and imperceptibility, and real-time properties. In addition, we were confirmed that the real-time embedding and detection from the streaming-based audio forensic marking system that has been implemented on the server/client is possible.

• Clinical and Experimental Pediatrics
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• v.53 no.12
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• pp.979-984
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• 2010

Recent progress in neonatal medicine has enabled survival of many extremely low-birth-weight infants. Prenatal steroids, surfactants, and non-invasive ventilation have helped reduce the incidence of the classical form of bronchopulmonary dysplasia characterized by marked fibrosis and emphysema. However, a new form of bronchopulmonary dysplasia marked by arrest of alveolarization remains a complication in the postnatal course of extremely low-birth-weight infants. To better understand this challenging complication, detailed alveolarization mechanisms should be delineated. Proper alveolarization involves the temporal and spatial coordination of a number of cells, mediators, and genes. Cross-talk between the mesenchyme and the epithelium through soluble and diffusible factors are key processes of alveolarization. Lung interstitial cells derived from the mesenchyme play a crucial role in alveolarization. Peak alveolar formation coincides with intense lung interstitial cell proliferation. Myofibroblasts are essential for secondary septation, a critical process of alveolarization, and localize to the front lines of alveologenesis. The differentiation and migration of myofibroblasts are strictly controlled by various mediators and genes. Disruption of this finely controlled mechanism leads to abnormal alveolarization. Since arrest in alveolarization is a hallmark of a new form of bronchopulmonary dysplasia, knowledge regarding the role of lung interstitial cells during alveolarization and their control mechanism will enable us to find more specific therapeutic strategies for bronchopulmonary dysplasia. In this review, the role of lung interstitial cells during alveolarization and control mechanisms of their differentiation and migration will be discussed.

• Archives of Plastic Surgery
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• v.45 no.2
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• pp.152-157
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• 2018

Background Intraoperative indocyanine green (ICG) lymphography can effectively detect functioning lymph vessels in edematous limbs. However, it is sometimes difficult to clearly identify their course in later-stage edematous limbs. For this reason, many surgeons rely on experience when they decide where to make the skin incision to locate the lymphatic vessels. The purpose of this study was to elucidate lymphatic vessel flow patterns in healthy upper extremities in a Korean population and to use these findings as a reference for lymphedema treatment. Methods ICG fluorescence lymphography was performed by injecting 1 mL of ICG into the second web space of the hand. After 4 hours, fluorescence images of lymphatic vessels were obtained with a near-infrared camera, and the lymphatic vessels were marked. Three landmarks were designated: the radial styloid process, the mid-portion of the cubital fossa, and the lower border of the deltopectoral groove. A straight line connecting the points was drawn, and the distance between the connected lines and the marked lymphatic vessels was measured at 8 points. Results There were 30 healthy upper extremities (15 right and 15 left). The average course of the main lymph vessels passed $26.0{\pm}11.6mm$ dorsal to the styloid process, $5.7{\pm}40.7mm$ medial to the mid-cubital fossa, and $31.3{\pm}26.1mm$ medial to the three-quarters point of the upper landmark line. Conclusions The main functioning lymphatic vessel follows the course of the cephalic vein at the forearm level, crosses the mid-cubital point, and travels medially toward the mid-axilla.

• Korean Management Science Review
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• v.13 no.1
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• pp.135-156
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• 1996

The purpose of this paper is to study the links between manufacturing strategy and change programs of manufacturing firms in Korea. The nature of our analysis is more descriptive than normative or confirmative. First, we investigate the linkage between manufacturing strategy, manufacturing capability, change programs and performance measurement systems. Secondly, we intend to explore an empirical typology of manufacturing strategy and change programs. The initial findings of the study are as follows: Linkage between manufacturing strategy and change programs of manufacturing firms was not apparent. Flexibility as a strategic priority is positively related to the innovative change programs. There are two distinctive strategies of manufacturing firms in Korea, namely, quality strategy and balanced strategy. We identified three types of change programs, which are incremental change, administrative innovation, and process innovation. Incremental change group has represented low factor score in the change program dimensions. The firms in administrative innovation group mainly depend on information systems and business reengineering. Korean manufacturing firms seem to pursue process improvement by trying simultaneously incremental change in the process, managerial process improvement, and a little bit of innovative change. Performance variable utilization of the firms are not significantly different along with manufacturing strategies and change programs. We found, however, learning and improvement performance dimension is significantly related to flexibility variables. Process innovation group marked high score in usage of learning and improvement indices. The findings of this study seem to have various implications on realigning the manufacturing strategy, change programs, and performance systems in Korean firms.

• Medical Lasers
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• v.9 no.1
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• pp.71-75
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• 2020

Eagle syndrome is relatively uncommon with an incidence of abnormal stylohyoid length being 4% to 7.3%. A vast majority of individuals with elongation of the styloid process are asymptomatic. It is a syndrome marked by the clinical signs and symptoms of facial pain, ear pain, throat pain, dysphagia and a globus sensation in the throat. The cause of Eagle syndrome is believed to be a congenital or hormonal change and reactive osseus hyperplasia of the styloid process in response to pharyngeal trauma or surgical intervention, such as tonsillectomy. We present here a case of a 37-year-old female with a twelve-month history of both sided oropharyngeal pain and globus sensation which has no trauma or surgical intervention. The patient presented with a long, slender, bony intraoral projection that was found to be an elongated styloid process. We removed this elongated styloid process with a CO₂ laser, and her symptoms disappeared.

• Journal of Families and Better Life
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• v.18 no.3 s.47
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• pp.71-84
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• 2000

The purpose of this study is to analyze the structure of maternal experiences. This study applies ethnographic case study, interview data were collected through in-depth interviews of 10 key interviewees. Findings were as follows: (1) Experiences of the body were about creating a new being through the pain of giving a birth and differed according to woman's self-evaluation of identity. (2) Child-rearing experiences marked a shift of position from a child to a parent. Interviewees experienced the hardhsip of life as a mother, its meanings differed according to the social context of interviewees. Child-rearing experiences meant a process of personal maturity. (3) Mother-child relationship shaped by child-rearing experiences, is a process of building meanings. It led to empathy and reinterpretation of her mother's life.

• Proceedings of the Korean Society of Machine Tool Engineers Conference
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• 2001.04a
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• pp.115-118
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• 2001

An image processing method was applied to characterize a shape of the flexible grinding disk. A disk surface image was taken by CCD camera. Depth of cut was changed to be 2 and 4mm. Circles marked on the disk were captured to extract the key features of the deflection. Notable correlation has been observed between the intervals and the process conditions. Same methodology has been applied to check the symmetry of the human face. Tentative results revealed that symmetry could be checked using the filtered face image.

• Journal of Korean Neurosurgical Society
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• v.51 no.1
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• pp.54-58
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• 2012

We present the rare case of solitary xanthogranuloma in the upper cervical column mimicking a Brown-Sequard syndrome. A 29-year-old man complained with right hemiparesis and left hypoesthesia after a car accident. Computed tomography and magnetic resonance images revealed a lobulated homogenously well-enhancing mass in between posterior arch of the atlas (C1) and spinous process of the axis (C2) resulting in a marked spinal canal narrowing with cortical erosions. The patient was managed by complete resection of the tumor with partial laminectomy with lower half of C1 posterior arch and upper half of C2 spinous process. The authors advise complete removal of the xanthogranuloma and consideration as a differential diagnosis of lesions among upper cervical lesions.

• Proceedings of the Korean Society of Machine Tool Engineers Conference
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• 2000.10a
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• pp.314-319
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• 2000

The working surface of a flexible grinding disk was characterized by means of an image processing, in which a picture of a disk surface was taken by the CCD camera and analyzed with the personal computer. As process conditions, depth of cut was changed to be 2 and 4 mm. From the captured image circles marked on the disk was regenerated using the edges detected with scale space filtering. In order to correlate the level of deformation to the distortion of the circles, intervals between each circle have been analyzed. Notable correlation has been observed between the intervals and the process conditions.