• Journal of The Korean Society of Integrative Medicine
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• v.10 no.4
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• pp.121-136
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• 2022

Purpose : Marine therapy is an activity that promotes public health such as constitution improvement, immunity improvement, and anti-aging by utilizing marine therapeutic resources such as seawater, mud, seaweed, salt and sea climate. In Europe developed countries, the marine therapy industry has been developing for centuries, with France, Germany, and Israel leading the way. Currently, it has achieved great industrial achievements and is of great help in improving the human health. The purpose of this study is to investigate how marine therapeutic resources benefit to human health, as well as how to study and utilize their efficacy. We analyzed previous research articles related to the effects of marine therapeutic resources. Methods : The study included a total of 830 published literatures in the last 20 years from the Republic of Korea and other contries. PubMed and Google Scholar were utilized to collect the foreign source while the local scientific publications were accessed through the Korean Education and research Information Service (KERIS) and Korean studies Information Service System (KISS). The keywords used to search foreign literature were "marine therapy", "Thalassotherapy", "seawater", "deep seawater", "saline groundwater", "sand therapy", "mud therapy", "hydrotherapy", "seaweed", "Sun light", "sea salt", "marine animal", and "marine microorganisms" were combined, and for the domestic literature, the keywords were "marine therapy", "marine therapeutic resources", "seawater", and "sand". Results : A total of 830 research papers were found as a result of searching for domestic and international papers related to marine therapeutic resources. The collected documents were classified into 175 seawater resources, 259 marine mineral resources, 41 marine environment, and 355 marine organisms. The efficacy of each marine therapeutic resources was analyzed. By resources type, there were about 213 papers on the efficacy of seaweed, followed by about 175 papers on seawater, 142 on microorganisms, 124 on mud/peat, and sand, salt, minerals and others are appeared in order (Table 1). Conclusion : Korea has the highest marine biodiversity index, excellent tidal flats, four distinct seasons, and various sea environments of the East sea, Yellow sea, South sea and Jeju sea. For this reason, Korea has a much more diverse marine therapeutic resources than other advanced countries in the marine therapy industry. prebiously, we thought that the sea was only valuable as a shipping port and fishery industry. But now, it been shown that the ocean can become a new industrial field which can contribute to human health and well-being by providing healing and therapy to people through the gift of marine resources.

• Proceedings of KOSOMES biannual meeting
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• 2018.06a
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• pp.64-64
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• 2018

• Journal of Fisheries and Marine Sciences Education
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• v.28 no.3
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• pp.808-817
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• 2016

This study aims at reviewing differences of awareness toward speech-language therapy according to background variables of child-care teachers, and establishing a basic data necessary for special education support programs afterwards based on child-care centers and its characteristics with the results. Researcher carried out a survey by objecting child-care teachers of Chungcheongbuk-do, Korea, and looked into existence of some differences through SPSS 20.0 for Window, independent sample t-Test, ANOVA, Scheffe post verification on background characteristics such as level of education, working career, license grade, whether or not to have objects of speech-language objects in the class. Research results are same as follows. First, significant differences in awareness of child-care teachers toward speech-language therapy appeared from license grade among characteristics like level of education, license grade, whether or not to have objects of speech-language therapy in the class. Second, significant differences were displayed from whether or not to have objects of speech-language therapy in the class among characteristics such as level of education, working career, license grade, and whether or not to have objects of speech-language therapy. When putting these results together, a conclusion could be made such like awareness of child-care teachers toward speech-language therapy and therapists is able to be different a little according to background variables of teachers.

• Journal of Fisheries and Marine Sciences Education
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• v.28 no.1
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• pp.266-278
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• 2016

The purpose of this research is to derived art therapy program according to the personality type of student with intellectual disabilities. In order to complete the purpose, Focus group interview method by eight experts in order to achieve the objet of the study were done. The interviews were first derived the information about the programs details process, secondary interviews, it obtained the information through primary and a second interview is as follows: First, the program detail interviews activity periods, action steps for activity goals, activity type and activity restrictions material set, the configuration and action programs, time, set a place, whereby the developed final art therapy program.

• Journal of Fisheries and Marine Sciences Education
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• v.24 no.6
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• pp.806-819
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• 2012

The objective of this study is to assess the effect of art activities of young children by utilizing the art therapy techniques on the daily stress and social competence of the young children. Out of children at the age of 5 in two classes of H kindergarten in P city, the study of 25 and controlling group of 25 are allocated to make a total number of 50 study objects. After pretests on the surveyed and controlling groups, 2-3times a week, totaling 12times of experimental treatments are made by selecting the art works of easy application on the education fields for the young children. The outcome of this study is as follow. First, the surveyed group participating in the art activities based on art therapy techniques gets lower points than the controlling group in criticism-attacking circumstance, anxious-frustrated circumstance, pride-deteriorated situation and the general daily stress. Second, the surveyed group participating in the art activities based on art therapy techniques gets higher points than the controlling group in positive-social activities, anxious-contracted activities, angry-aggressive activities and the general social competency.

• Journal of Fisheries and Marine Sciences Education
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• v.28 no.5
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• pp.1395-1406
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• 2016

The purpose of this study was to examine the effects of interaction based mother-child art therapy on the change of child and mother's interactions in a child who was in trouble due to attachment problems. The subject in this study was a six-year-old child who faced difficulties in peer relationship building and who were maladjusted to kindergarten because of unstable attachment and negative feedback from his parents. Also, he showed serious problem behaviors at home. The ABA design was adopted among single-subject research designs, and the Target child was observed in the sessions in terms of the subfactors of Marschak's Behavioral Rating Scale to gather data related to the changes of child and mother's interactions. As a result of analyzing the collected data, there were positive changes in all the subfactors that were the child's verbal/nonverbal interactions, the mother's verbal/nonverbal interactions and mother-child interactions. Therefore the interaction based mother-child art therapy that was designed to boost child and mother's interactions was effective at furthering the mother-child interactions of the child with attachment problems.

• Journal of The Korean Society of Integrative Medicine
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• v.10 no.4
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• pp.261-275
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• 2022

Purpose : According to the Korean Diabetes Association, the number of metabolic disease patients in Korea is approximately 14.97 million as of 2020;, the prevalence of diabetes among adults over 30 years old is 44.3 %, and the prevalence of diabetes in the elderly over 65 years old is 50.4%. These individuals exposed to the risk of complications. Therefore, the purpose of this study was to determine a distribution method for a customized fusion exercise marine healing program for metabolic disease patients. Methods : We have searched numerous papers concerning artificial intelligence (AI), virtual reality (VR), augmented reality (AR), and marine resources related to marine healing programs that can be introduced in marine healing centers for people with metabolic diseases Results : Through the production of various marine resources and evidence-based exercise programs, the provision of exercise programs using AI, and the development of exercise platforms using AR and VR, we were able to establish guidelines for how to operate marine healing programs at marine healing centers. Conclusion : Korea has much more diverse marine healing resources than other advanced countries in the marine healing industry. However, the development of these resources has only just begun. It is hoped that the studied marine healing program will be of great help to metabolic patients by creating contents that will be implemented in marine healing centers by using the cutting-edge technologies and various marine resources that Korea possesses.

• Fisheries and Aquatic Sciences
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• v.13 no.3
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• pp.216-223
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• 2010

Abalone (Haliotis discus hannai), mostly distributed and maricultured in southwestern coastal areas of South Korea, is recognized as an economically important species in the fishery industry. Abalone intestines are one of the by-products of abalone processing. To investigate abalone intestines as bioactive substances, abalone intestine gastrointestinal digests (AIGIDs) of various molecular weights (MWs) were prepared using in vitro gastrointestinal digestion and an ultrafiltration system, and tested for inhibitory effects against reactive oxygen species (ROS) and oxidative stress in macrophage cells treated with hydrogen peroxide ($H_2O_2$). In our results, among AIGIDs, AIGID-III (MW=5-10 kDa) showed potent inhibitory activities for lipid peroxidation and free radicals. Additionally, the results clearly indicated that AIGID-III treatment could prevent cytotoxic damage of macrophages by $H_2O_2$-induced oxidative stress due to its potent scavenging ability against cellular ROS. These results suggest that AIGIDs may have protective and therapeutic potential for oxidative stress syndromes and immune diseases through ROS inhibition in macrophage cells.

• Journal of the Korean Association of Geographic Information Studies
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• v.22 no.4
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• pp.146-157
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• 2019

This study, as a pilot study to implement and extend the marine healing which has been rapidly extending oversea areas into the domestic market, has collected seven major marine healing resources such as ocean water, sand, salt, mud, seaweeds, forest, and weather targeting selected four pilot municipalities and established a GIS DB. Furthermore, web GIS based marine healing portal has been established to support the easier utilization of the GIS DB and various marine healing related contents, thereby facilitating expansion of related industry. The portal includes marine thematic maps as well as research papers, related therapy manuals, and various activities and programs of the pilot municipalities. It is expected that the portal would contribute to the expansion of the domestic marine healing industry significantly through the pilot operation of the portal, not to mention of the needs of subsequent studies for expansion of the marine GIS DB and securing more various contents.

• The Korean Journal of Physiology and Pharmacology
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• v.26 no.1
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• pp.15-24
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• 2022

The development of selective targeting of drug molecules towards the mitochondria is an important issue related to therapy efficacy. In this study, we report that gallic acid (GA)-mitochondria targeting sequence (MTS)-H₃R₉ exhibits a dual role as a mitochondria-targeting vehicle with antioxidant activity for disease therapy. In viability assays, GA-MTS-H₃R₉ showed a better rescue action compared to that of MTS-H₃R₉. GA-MTS-H₃R₉ dramatically exhibited cell penetration and intercellular uptake compared to MTS and fit escape from lysosome release to the cytosol. We demonstrated the useful targeting of GA-MTS-H₃R₉ towards mitochondria in AC16 cells. Also, we observed that the antioxidant properties of mitochondrial-accrued GA-MTS-H₃R₉ alleviated cell damage by reactive oxygen species production and disrupted mitochondrial membrane potential. GA-MTS-H₃R₉ showed a very increased cytoprotective effect against anticancer activity compared to that of MTS-H₃R₉. We showed that GA-MTS-H₃R₉ can act as a vehicle for mitochondria-targeting and as a reagent for therapeutic applications intended for cardiovascular disease treatment.