• The Korean Journal of Physiology and Pharmacology
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• v.21 no.1
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• pp.91-97
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• 2017

Hyperglycemia is associated with an increased risk of cardiovascular diseases. It has been demonstrated that chronic exposure to high glucose impaired endothelial functions. However, specific effects of short-term exposure to high glucose on vascular reactivity are controversial. Moreover, the combined effects of other metabolic substrates such as free fatty acids (FFA) on vascular reactivity remain poorly understood. Here we investigate the effects of short-term exposure to high glucose with or without other metabolic substrates including FFAs termed "nutrition full" (NF) solution, on mesenteric (MA) and deep femoral arteries (DFA) of rats. Arterial ring segments were mounted in a double-wire myograph. Contraction in response to phenylephrine (PhE) was determined in control (5 mM) and high glucose (23 mM, HG) environments over a 30 min period. In both arteries, PhE-inducedvasocontraction was enhanced by pre-incubation of HG solution. A combined incubation with HG and palmitic acid ($100{\mu}M$) induced similar sensitization of PhE-contractions in both arteries. In contrast, high $K^+$-induced contractions were not affected by HG. Interestingly, pre-incubation with NF solution decreased PhE-induced contraction in MA but increased the contraction in DFA. In NF solution, the HG-induced facilitation of PhE-contraction was not observed in MA. Furthermore, the PhE-induced contraction of DFA was attenuated by HG in NF solution. Our results demonstrate that the sensitization of PhE-induced arterial contraction by HG is differentially affected by other metabolic substrates. The conversation of skeletal arterial contractility by HG in NF solution requires careful interpretation of the previous in vitro studies where only glucose is included in physiological salt solutions. Further studies are required to elucidate the mechanism underlying the inconsistent effect of NF solution on MA and DFA.

• Journal of the Korean Home Economics Association
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• v.44 no.5 s.219
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• pp.99-107
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• 2006

The purposes of this study are to identify the types of teacher efficacy, to present a theoretical base for teacher efficacy among Home Economics teachers and subsequently, to improve the quality in the practices of home economics education. To achieve these purposes, 263 secondary school home economics teachers were surveyed by the prime investigator. The three research questions of this study were: 1. What are the individual characteristics, the environmental characteristics and the trends of teacher efficacy among secondary school home economics teachers? 2. What is the factor in teacher efficacy among secondary school home economics teachers? 3. What are the types of teacher efficacy among secondary school home economics teachers? For these research questions, factor analysis and cluster analysis were conducted. The factor analysis on teacher efficacy with a survey of secondary school home economics teachers produced 5 factors of efficacy: classroom management, needs assistance, instructional strategies, environmental assistance and teaming assistance. The teacher efficacy had a mean of 3.58 and the home economics teachers showed a slightly higher level in teacher efficacy. Of the 5 efficacy factors, classroom management showed the highest level (M=3.89), followed by learning assistance (M=3.81), instrumental strategies (M=3.57), environmental assistance (M=3.42) and needs assistance (M=3.19). Overall, the teachers had positive feeling in teacher efficacy. Three types of teachers were found in the types of teacher efficacy: the supreme, the average and the efforts-needy. Those types were identified based on the mean scores of the five sub-domains from the factor analysis. To enhance the teacher efficacy, the needs assessments for the students and behavioral adjustment issues should be reflected in the curriculum of teacher education and workshops. The primary investigator suggested that continuous and long-term plans for teacher education need to be developed because short-term plans may not be effective in changing attitudes such as teacher efficacy.

• Journal of the Korean Chemical Society
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• v.35 no.2
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• pp.111-118
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• 1991

The kinetic of the gas phase reactions of ozone(0.5 torr) with sulfur dioxide was studied. The SO2 reaction was conducted in the 7∼22 torr range at 90∼155$^{\circ}$C. The reaction rate was faster than the reaction rate of O$_3$ in the presence of CO$_2$ alone. The reaction of O$_3$ with SO$_2$ follows the rate law: -d(O$_3)/dt=k_0(SO_2)(M)(O_3)+2k _1(SO_2)(O_3$). The first term of this rate law arises from a third order molecular reaction predominating in the lower temperature range and gave a rate constant k$_0$ = (9.35 $\pm$ 8.6) ${\times}$ 10$^9$e$^{-(11.05{\pm}2.04)kcal/RT}(M^{-2}s^{-1}$). The second term of the above rate law derived from a second order thermal decomposition reaction which was the major part of the reaction and gave a rate constant k$_0 =(9.35{\pm}8.6){\times}10^9e^{-(11.05{\pm}2.04)kcal/RT}(M^{-2}s^{-1}$). The overall reaction proceeds with kinetics of complex order composed mainly of second order and third order components.

• Korean Journal of Construction Engineering and Management
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• v.5 no.2 s.18
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• pp.211-218
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• 2004

In a large owner organization, a program manager of multiple maintenance and remodeling projects has experienced increasing scale and complexity of coordinating the M/R projects with in-house technicians who belong to multiple trade shops. This paper proposes a dual-level hierarchical planning strategy that consists of a program master plan in the long-term horizon and a master construction schedule in an operational scheduling window. A rolling horizon approach to the program master plan is proposed to deal with the external uncertainty of unknown stream of project requests. A resource-constrained scheduling algorithm is developed to generate the master construction schedule in a scheduling window. During development of the algorithm, more emphasis is placed on long-term organizational resource continuity, especially flow management of program constraint resources, than ephemeral events of an individual activity and project. Monte Carlo simulation experiments of three scheduling windows are used to evaluate the relative performance of the proposed scheduling algorithm against three popular scheduling heuristics for resource-constrained multiple projects.

• International Journal of Highway Engineering
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• v.9 no.3
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• pp.101-110
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• 2007

Joint Spacing of Jointed Concrete Pavement has been uniformly designed and constructed as six-meter in Korea. However, engineering backgrounds to show the appropriateness of six-meter Joint Spacing has not been provided. In the on-going reseach of the development of Korea Pavement Reseach Program(KPRP), the optimum Joint Spacing is suggested as 6 to 8 meters according to the regional climatic conditions based on the mechanical-empirical analysis of short-term and long-term pavement distress. This study is a part of the investigation on the adequateness of Joint Spacing design specification suggested in KPRP. Joint Spacing was design and constructed as seven-meter Joint Spacing suggested as design specification in Korea Reseach Program(KPRP) and monitored the Load Transfer Efficiency(LTE), Random crack and compared with those of adjacent $6{\sim}7$ meter Joint Spacing concrete section.

• The Korean Journal of Nuclear Medicine
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• v.24 no.1
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• pp.108-118
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• 1990

It is well known that the glucocorticoid suppresses the osteoblast and the calcitonin suppresses the osteoclast. If the calcitonin prevents the osteoporosis with increased Tc-99m MDP uptake in the long-term use of glucocorticoid, then the calcitonin has some activating effect on the bone formation. The immobilization operation was done on the left hind-leg of 16 male Sprague-Dawley rats weighing about 300 g each. For 12 weeks after operation,8 rats were injected 0.5 mg/kg dexamethasone, and the other 8 rats were injected 0.5 mg/kg dexamethasone and $1\;\bar{u}/kg$ eel calcitonin. The bone mineral content was measured by the single photon absorptiometry and the Tc-99m MDP uptake was used as an index of the osteoblastic activity. 1) The Tc-99m MDP uptakes in the dexamethasone treated group were lower than those in the dexamethasone and calcitonin treated group, and there was no significant difference in Tc-99m MDP uptakes between the immobilized and normal femurs. 2) The bone mineral contents in the dexamethasone treated group were significantly lower than in the dexamethasone and calcitonin treated group, and the immobilized femurs had tower BMC than normal femurs. 3) The slope of regression between the BMC and Tc-99m MDP uptake was stiff in the dexamethasone treated group, and flat in the dexamethasone and calcitonin group, which shows discrepancy between the bone resorption and formation resulting prevention of net bone loss in the dexamethasone and calcitonin treated group. In conclusion, the calcitonin has some effect on the bone formation, and further studies with urinary hydroxyproline and cyclic AMP are expected.

• Electronics and Telecommunications Trends
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• v.27 no.2
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• pp.59-69
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• 2012

모든 사물들을 네트워크를 통해 연결하므로 언제 어디서나 다양한 서비스를 손쉽게 이용할 수 있게 하는 M2M(Machine to Machine)/IoT(Internet of Things)가 차세대 통신을 위한 주요 이슈로 고려되고 있으며, 여러 네트워크 중 이동통신 네트워크를 기반으로 하는 M2M에 대한 관심이 고조되고 있다. UMTS(Universal Mobile Telecom. System), LTE(Long Term Evolution) 등 대표적인 이동통신 시스템을 위한 표준화 단체인 3GPP(3rd Generation Partnership Project)에서는 2005년 M2M을 위한 타당성 연구를 시작으로, 2008년부터 Machine Type Communications(MTC)를 위한 본격적인 표준화 작업이 진행되었으며, 현재 Release 10을 위한 규격 작업을 마무리하고 Release 11 및 12를 위한 표준규격을 작성하고 있다. 본고에서는 3GPP에서 진행하고 있는 MTC의 표준화 현황을 간략히 기술한다.

• ETRI Journal
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• v.34 no.5
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• pp.759-762
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• 2012

Carrier aggregation is an essential feature in the Long Term Evolution-Advanced (LTE-A) system, which allows the scalable expansion of the effective bandwidth to be delivered to user equipment (UE) through the concurrent use of radio resources across multiple component carriers (CCs). This system's optimal radio-resource use has received much attention under simultaneous access (SA) scenarios for multiple CCs (m-CCs). This letter establishes how many CCs a UE should simultaneously connect to maintain maximum uplink capacity. Under the m-CC LTE-A system, the spectral efficiency of the m-CC SA scheme ($m{\geq}2$) is compared with that of CC selection (CCS). Numerical results reveal that the 2-CC SA scheme outperforms CCS and performs almost equally to the m-CC SA scheme ($m{\geq}3$).

• The Korean Journal of Malacology
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• v.1 no.1
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• pp.5-12
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• 1985

The maturity of gonads, early development of the fertilized egg, spawning period, and morphogenesis of larvae in Limnoperua fortunei were studied from October, 1981 to November, 1982 as on attempt to identify its life cycle. 1) Active motility of its sperm was observed at late May, and matured egg could be found at late June. 2) It was estimated that the spawning was occured from late August. This species was belong to the short-term breeder because it finished its spawning within 20 days. 3) It has free-living trochophore and D-shaped larva stage. The shell lengths of early, middle, and D-larval stage were $140.0{\mu}m$, $167.6{\mu}m$ and $210.0{\mu}m$, respectively. The shell heigths of each stage were $97.3{\mu}m$, $137.6{\mu}m$ and $178.2{\mu}m$, respectively.

• Molecules and Cells
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• v.39 no.12
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• pp.841-846
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• 2016

Local protein synthesis mediates precise spatio-temporal regulation of gene expression for neuronal functions such as long-term plasticity, axon guidance and regeneration. To reveal the underlying mechanisms of local translation, it is crucial to understand mRNA transport, localization and translation in live neurons. Among various techniques for mRNA analysis, fluorescence microscopy has been widely used as the most direct method to study localization of mRNA. Live-cell imaging of single RNA molecules is particularly advantageous to dissect the highly heterogeneous and dynamic nature of messenger ribonucleoprotein (mRNP) complexes in neurons. Here, we review recent advances in the study of mRNA localization and translation in live neurons using novel techniques for single-RNA imaging.