• Geomechanics and Engineering
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• v.31 no.1
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• pp.31-52
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• 2022

Investigating and evaluating the long-term creep behavior of historical buildings built on seismic zones is of great importance in terms of transferring these structures to future generations. Furthermore, assessing the earthquake behavior of historical structures such as masonry stone bridges is very important for the future and seismic safety of these structures. For this reason, in this study, earthquake analyses of a masonry stone bridge are carried out considering strong ground motions and various water levels. Tokatli masonry stone arch bridge that was built in the 10th century in Turkey-Karabük is selected for three-dimensional (3D) finite difference analyses and this bridge is modeled using FLAC3D software based on the three-dimensional finite difference method. Firstly, each stone element of the bridge is modeled separately and special stiffness parameters are defined between each stone element. Thanks to these parameters, the interaction conditions between each stone element are provided. Then, the Burger-Creep and Drucker-Prager material models are defined to arch material, rockfill material for evaluating the creep and seismic failure behaviors of the bridge. Besides, the boundaries of the 3D model of the bridge are modeled by considering the free-field and quiet boundary conditions, which were not considered in the past for the seismic behavior of masonry bridges. The bridge is analyzed for 6 different water levels and these water levels are 0 m, 30 m, 60 m, 70 m, 80 m, and 90 m, respectively. A total of 10 different seismic analyzes are performed and according to the seismic analysis results, it is concluded that historical stone bridges exhibit different seismic behaviors under different water levels. Moreover, it is openly seen that the water level is of great importance in terms of earthquake safety of historical stone bridges built in earthquake zones. For this reason, it is strongly recommended to consider the water levels while strengthening and analyzing the historical stone bridges.

• Journal of Radiation Protection and Research
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• v.26 no.3
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• pp.315-319
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• 2001

It is shown, that both cosmic radiation (external source) and natural radioactive gases (inner source) are sources of neutrons near the Earth crust. Correlation between the Earth crust dynamics and variations of thermal and slow neutron flux near the Earth surface is studied. It is shown, that variations of neutron flux near the Earth crust can be used for short-term predicting of natural hazards.

• International Journal of Stem Cells
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• v.16 no.1
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• pp.117-122
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• 2023

Background and Objectives: mRNA-based protein expression technology has been used to express functional proteins. We have previously generated dopamine neurons from rat-embryo derived neural precursor cells (NPCs) through repeated transfection of synthetic transcription factor mRNA encoding dopamine-inducible genes. However, NPCs began to die approximately 10 d post-transfection. In this study, we examined a long-term transfection protocol that did not affect cell viability. Methods and Results: Experiments were performed in eight groups sorted according to the start date of mRNA transfection. mRNA was transfected into NPCs daily for 21 d and live cell images of each group were recorded. NPCs which were differentiated for more than five days showed sustained gene expression and appreciable viability despite daily mRNA transfection for 21 d. Conclusions: Repeated mRNA transfection requires cells with a sufficient differentiation period.

• Journal of Korean society of Dental Hygiene
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• v.9 no.2
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• pp.57-71
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• 2009

This study aims to investigate the stress factors of students in Dental Hygiene Department who will soon take the national examination, corresponding countermeasures and relationship of internal and external personality. On the basis of the results from investigation, this study will identify the methods to effectively cope with stress and to take the national examination with more positive thinking for the students and faculty members in Dental Hygiene Department, who have to pass the difficult test, the national examination. The structured questionnaires were given to junior students in Dental Hygiene Department in three colleges, to identify the stress factors, methods to deal with stress and A/B personality types. For the stress factor by field, the M college showed significantly higher stress about curriculum and assignment than the C college. In the stress factor analysis by item, the lack of information on national examination in the test area, all items in learning environment, a quantity of assignment that doesn't help the preparation of national examination in the assignment area, and lack of information on employment in job area demonstrated the significant difference(p<0.05). For the methods of subjects to deal with stress, several subcategories of long-term and short-term adaptation had significance. In case of the methods to deal with stress by personality type, B type in the short-term adaptation method in M college and A type in the long-term adaptation method in C college were significantly higher(p<0.05). As for the correlation between the population sociological features and stress factors by personality type, health status had the high correlation with test in the test area. In other areas, the travel hours to school showed the significant correlation. The higher the records were, the longer the travel hours were and the better the health status was, the higher the long-term adaptation method scores were. Moreover, the personality of A type showed the higher scores in the long-term adaptation method than that of B type. The health status and personality type showed the significant correlation(p<0.05). In conclusion, it is required to prevent any situations b identify the personality type and stress reasons of the students in Dental Hygiene Department who will take the national examination soon. The additional requirement is the continuing interest and counseling of faculty members to help students to cope with stress with positive attitude.

• Journal of Korea Port Economic Association
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• v.28 no.1
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• pp.179-201
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• 2012

Since 1993, M&A activities have been frequent in Liner shipping market. This study examines the effect of M&A on stock price reaction for acquiring firms listed on the market. The study covers the period from 1993 to 2009 and uses 61 daily closing prices of the acquiring firms before and after the M&A announcement day and is analyzed through the market-adjusted model in an event study. After calculating short-term performance using abnormal returns(AR) and cumulative average abnormal returns(CAR) before and after 30 days from the day of event, the results on the test show that the firm's values slightly increased through the M&A, but it does not attest to the statistical significance. In addition, this study investigates the AR difference between estimating windows and post-event windows for the 3 cases of each period before and after 30 days, 15 days, and 7 days from the event day to analyse the impact of M&A on the addition of acquiring firm's value. Our findings suggest that the M&A between Liner shipping companies is targeted for the long-term business strategy instead of the instant rise in the value of the firm involved.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.6
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• pp.278-290
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• 2016

The purpose of this study is to investigate the association of total cholesterol levels (TC) and the incidence of hypercholesterolemia in response to changes in BMI. The subjects included a total of 28,249 industrial workers (25,548 male and 2,701 female) aged 30-69 years old who had received regular medical check-ups at least once per year from 2002 to 2012 (over 11 years). Data from this period were categorized into a first term (2002-2005), middle term (2006-2009), and last term (2010-2012). Then, the average TC was stratified by BMI, which was obtained from the initial examination results of each individual. In addition, average changes in TC were analyzed by stratifying with changes in BMI over 10 years (starting in 2002). The annual occurrence rates of hypercholesterolemia stratified by BMI were further assessed in patients with normal ranges of TC. In all three terms, the average TC was significantly elevated in the obese group ($25.0kg/m^2$) compared to the low weight group ($18.5kg/m^2$) and the normal weight group ($18.5-25.0kg/m^2$). Similarly, the group with higher BMI presented elevated rates of hypercholesterolemia compared to the groups with low BMI. In addition, increased BMI over the 10 year period significantly influenced TC. Consequently, it is suggested that evaluation and intervention for obesity control may be needed in order to manage the risk of high serum lipid levels.

• Korean Journal of Remote Sensing
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• v.34 no.3
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• pp.495-506
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• 2018

Global interest in climate change and sea level rise has led to active research on the velocities of glaciers. In studies about the velocity of glaciers, in-situ measurements can obtain the most accurate data but have limitations to acquire periodical or long-term data. Offset tracking using SAR is actively being used as an alternative of in-situ measurements. Offset tracking has a limitation in that the accuracy of observation is lower than that of other observational techniques, but it has been improved by recent studies. Recent studies in the $Uv{\hat{e}}rsbreen$ glacier area have shown that glacier altitudes decrease at a rate of 1.5 m/year. The glacier displacement velocities in this region are heavily influenced by climate change and can be important in monitoring and forecasting long-term climate change. However, there are few concrete examples of research in this area. In this study, we applied the improved offset tracking method to observe the two-dimensional velocity in the $Uv{\hat{e}}rsbreen$ glacier. As a result, it was confirmed that the glacier moved at a maximum rate of 133.7 m/year. The measruement precisions for azimuth and line-of-sight directions were 5.4 and 3.3 m/year respectively. These results will be utilized to study long-term changes in elevation of glaciers and to study environmental impacts due to climate change.

• Bulletin of the Korean Mathematical Society
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• v.46 no.1
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• pp.117-123
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• 2009

This paper is a study of some properties of a collection of bounded linear operators resulting from terraced matrices M acting through multiplication on ${\ell}^2$; the term terraced matrix refers to a lower triangular infinite matrix with constant row segments. Sufficient conditions are found for M to be posinormal, meaning that $MM^*=M^*PM$ for some positive operator P on ${\ell}^2$; these conditions lead to new sufficient conditions for the hyponormality of M. Sufficient conditions are also found for the adjoint $M^*$ to be posinormal, and it is observed that, unless M is essentially trivial, $M^*$ cannot be hyponormal. A few examples are considered that exhibit special behavior.

• Journal of Radiation Protection and Research
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• v.16 no.1
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• pp.1-13
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• 1991

Effective dose equivalents resulting from inhalation of indoor radon-222 daughters at 12 residential areas in Korea were assessed by a simple mathematical lung dosimetry model based on the measurements of long-term averaged radon concentrations at 340 dwellings. The long-term averaged indoor radon-222 concentrations and corresponding eqilibrium equivalent radon $concentration(EEC_{Rn})$ measured by passive time-integrating CR-39 radon cups are in the range of $33.82{\sim}61.42Bq/m^3(median\;:\;48.90Bq/m^3)$ and of $13.53{\sim}24.57Bq/m^3(median\;:\;19.55Bq/m^3)$, respectively. The effective dose equvalent conversion factor for the exposure to unit $EEC_{Rn}$ derived in this study was estimated $1.07{\times}10^{-5}mSv/Bq\;h\;m^{-3}$ for a reference adult and agreed well with those recommended by the ICRP and UNSCEAR. The annual average dose equivalent to the lung $(H_{LUNG})$ from inhalation exposure to measured $EEC_{Rn}$ was estimated to be 20.90 mSv and resulting effective dose $equivalent(H_E)$ was to be 1.25 mSv, which is about 50% of the natural radiation exposure of 2.40 mSv/y to the public reported by the UNSCEAR.

• Tuberculosis and Respiratory Diseases
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• v.62 no.2
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• pp.98-104
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• 2007

Background: Although there is an increasing incidence of Mycobacterium abscessus pulmonary disease in Korea, the optimal therapeutic regimen has not yet been established and there are no reports of the long-term treatment outcomes. This study examined the long-term treatment outcomes of M. abscessus pulmonary disease. Methods: Twenty-nine patients diagnosed with M. abscessus pulmonary according to the American Thoracic Society criteria and treated from January 1996 to December 2003 were enrolled in ghis study. The clinical characteristics, radiological findings, treatment outcome, and follow up data were analyzed retrospectively. Results: The mean age of the 29 patients was 56.1 (${\pm}13.6$) years and there was a female (22/29) dominance. The chest radiography revealed the nodular bronchiectatic type to be dominant (69%, 20/29). Twenty-seven (93.1%) were prescribed clarithromycin-containing regimens, and injectable drugs, mainly aminoglycosides, were included in the regimen of nineteen patients. The most predominant regimen (48.3%) consisted of clarithromycin and amikacin. The treatment success, failure, and default were achieved in 19(65.5%), 9(31.0%), and 1(3.4%), respectively. The median duration to culture conversion was 42 days (range 15-362) and the median duration of treatment in the success group was 543 days (range 176-1,160). An adjunctive surgical resection was performed in five patients, which resulted in treatment success in two patients. After the completion of treatment, nineteen patients were followed up for a median duration of 931 days (range 230-2,294). Only one (5.3%) patient relapsed 45 days after completing treatment. Conclusion: Treatment with clarithromycin-containing regimens resulted in a successful treatment in approximately two thirds of patients with M. abscessus pulmonary disease. The long-term relapse rate was also quite low.