Acknowledgement
This work was supported by the Individual Basic Science and Engineering Research Program (2019R1A2C2005681) of the National Research Foundation of the Ministry of Science and ICT in Korea.
References
- Sung YK, Kim SW. Recent advances in the development of gene delivery systems. Biomater Res 2019;23:8
- Sahin U, Kariko K, Tureci O. mRNA-based therapeutics--developing a new class of drugs. Nat Rev Drug Discov 2014;13:759-780 https://doi.org/10.1038/nrd4278
- McLenachan S, Zhang D, Palomo AB, Edel MJ, Chen FK. mRNA transfection of mouse and human neural stem cell cultures. PLoS One 2013;8:e83596
- Schlaeger TM, Daheron L, Brickler TR, Entwisle S, Chan K, Cianci A, DeVine A, Ettenger A, Fitzgerald K, Godfrey M, Gupta D, McPherson J, Malwadkar P, Gupta M, Bell B, Doi A, Jung N, Li X, Lynes MS, Brookes E, Cherry AB, Demirbas D, Tsankov AM, Zon LI, Rubin LL, Feinberg AP, Meissner A, Cowan CA, Daley GQ. A comparison of non-integrating reprogramming methods. Nat Biotechnol 2015;33:58-63 https://doi.org/10.1038/nbt.3070
- Yamamoto A, Kormann M, Rosenecker J, Rudolph C. Current prospects for mRNA gene delivery. Eur J Pharm Biopharm 2009;71:484-489 https://doi.org/10.1016/j.ejpb.2008.09.016
- Mandal PK, Rossi DJ. Reprogramming human fibroblasts to pluripotency using modified mRNA. Nat Protoc 2013;8:568-582 https://doi.org/10.1038/nprot.2013.019
- Kim SM, Lim MS, Lee EH, Jung SJ, Chung HY, Kim CH, Park CH. Efficient generation of dopamine neurons by synthetic transcription factor mRNAs. Mol Ther 2017;25:2028-2037 https://doi.org/10.1016/j.ymthe.2017.06.015
- Bulaklak K, Gersbach CA. The once and future gene therapy. Nat Commun 2020;11:5820
- Giamas G, Gagliano T. Cancer gene therapy 2020: highlights from a challenging year. Cancer Gene Ther 2022;29:1-3 https://doi.org/10.1038/s41417-021-00340-6
- Papanikolaou E, Bosio A. The promise and the hope of gene therapy. Front Genome Ed 2021;3:618346
- Bulcha JT, Wang Y, Ma H, Tai PWL, Gao G. Viral vector platforms within the gene therapy landscape. Signal Transduct Target Ther 2021;6:53
- Lundstrom K. Viral vectors in gene therapy. Diseases 2018;6:42
- Wang D, Tai PWL, Gao G. Adeno-associated virus vector as a platform for gene therapy delivery. Nat Rev Drug Discov 2019;18:358-378 https://doi.org/10.1038/s41573-019-0012-9
- Huang CL, Leblond AL, Turner EC, Kumar AH, Martin K, Whelan D, O'Sullivan DM, Caplice NM. Synthetic chemically modified mrna-based delivery of cytoprotective factor promotes early cardiomyocyte survival post-acute myocardial infarction. Mol Pharm 2015;12:991-996 https://doi.org/10.1021/mp5006239
- Zhou X, Hao R, Chen C, Su Z, Zhao L, Luo Z, Xie W. Rapid delivery of nanobodies/VHHs into living cells via expressing in vitro-transcribed mRNA. Mol Ther Methods Clin Dev 2020;17:401-408 https://doi.org/10.1016/j.omtm.2020.01.008
- Wang XF, Cynader MS. Effects of astrocytes on neuronal attachment and survival shown in a serum-free co-culture system. Brain Res Brain Res Protoc 1999;4:209-216 https://doi.org/10.1016/S1385-299X(99)00019-7
- Chang MY, Son H, Lee YS, Lee SH. Neurons and astrocytes secrete factors that cause stem cells to differentiate into neurons and astrocytes, respectively. Mol Cell Neurosci 2003;23:414-426 https://doi.org/10.1016/S1044-7431(03)00068-X
- Wang FW, Hao HB, Zhao SD, Zhang YM, Liu Q, Liu HJ, Liu SM, Yuan QH, Bing LJ, Ling EA, Hao AJ. Roles of activated astrocyte in neural stem cell proliferation and differentiation. Stem Cell Res 2011;7:41-53 https://doi.org/10.1016/j.scr.2011.03.004