• Journal of Haehwa Medicine
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• v.6 no.1
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• pp.555-566
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• 1997

This study was undertaken to identify the degree of burden and depression according to level of self-care activity and variables to which affect that in family caregivers of patients with stroke. The data were collected from October 23th to November 20th, 1995 The subjects in this study were 80 caregivers, that is, one family member and 80 patients with stroke who were hospitalized in one oriental medicine hospital in D city. The questionnaires consisted of questions regarding burden(13 items, 6 point scale), depression(20 items, 4 point scale), and self-care activity(15 items, 5 point sacle) Data were analyzed using percentages, means, t-test and ANOVA with the SAS program. The results of this study are as follows: 1) The mean score for client's self-care activity was 2.58. The highest score of the self-care activity item was 'returning'(M=3.604), and the lowest score of the self-care activity item was 'shower or tubbathing'(M=1.925). 2) the degrees of self-care activity according to the general characteristics of patients were tested. It was significantly different by sex(P<0.01), occupation(P<0.05), and relationships with patients(P<0.05). That is, the degree of self-care activity was higher in men than that of women, and caregiver with job than caregiver without that. In the case that caregiver was a patient's spouse, the degree of self-care activity was higher than other case. 3) The score for family caregiver's burden was higher than the mid level for the 13 items and caregiver's depression was relatively low. 4) According to the degree of self-care activity, the group was divided to 3, that is, A( 15-33), B(34-56), and C(57-75). The score of total burden was the highest in group A(M=55.257) and the lowest in group C(M=51.928), but there were no statistically significant differences between groups. The score of objective burden was the highest in group A(M=30.400), and the lowest in group C(M=25.214), and there were statistically significant differences between groups. The score of subjective burden was the highest in group B(M=26.000) and the lowest in group A(M=24.783), but there were no statistically significant differences between groups. The degree of depression was the highest in group A(M=44.750) and the lowest in group C(M=40.751), but there were no statistically significant differences between groups.

• Korean Journal of Child Studies
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• v.31 no.1
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• pp.19-33
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• 2010

This study examined the effects of family climate, peer support and self-esteem on children's self-regulation. The participants in this study were 369 children (M=11.78 year) who completed questionnaires regarding family climate, peer support, self-esteem and self-regulation. Data were analyzed means by of a Structural equation model using AMOS 7.0. Our results indicated that (1) family climate, peer support and self-esteem were directly linked with children's self-regulation (2) the associations between family climate or peer support and children's self-regulation were mediated by children's self-esteem. These results imply that family climate and peer support are important antecedent variables in predicting children's self-regulation as well as their relative levels of self-esteem.

• Journal of Family Relations
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• v.23 no.3
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• pp.3-29
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• 2018

Objectives: The purpose of this study was to investigate the acceptance of family diversity among college students and related variables. Method: Data were collected by a structured questionnaire with 280 students who attended in three universities located in J province. SPSS Statistics Program version 24.0 was used to analyze the collected data. To answer the research questions, descriptive statistics, t-test, F-test, Pearson's correlation analyses, and regression analyses were performed. Results: The major results of the survey were summarized as below. First, the acceptance of family diversity among college students was slightly higher than the middle level(M=12.11). Most students accepted nuclear family as a typical family. More than half of the students accepted single parent families, adaptive families, step families, unmarried mother families, childless couples, homosexual families, elderly women living alone, and families composed of siblings as a family. Second, there was a significant difference by religiosity. Students without religion were higher than their counterparts with religion in a level of family diversity acceptance. Among the individual factors, third, a level of traditional family value had a significant negative effect on a level of family diversity acceptance. And perspective taking had a positive effect on a level of family diversity acceptance. Fourth, among the family factors, parent-child open communication did not affect a level of family diversity acceptance. However, parents' gender egalitarian beliefs had a significant positive effect on a level of family diversity acceptance. Lastly, regarding the relative effects of the personal and family factors, the traditional family value had the largest effect on a level of family diversity acceptance among college students. Conclusions: Base on these results, the implications and limitations of the study were discussed.

• Proceeding of Spring/Autumn Annual Conference of KHA
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• 2008.11a
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• pp.379-384
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• 2008

The purpose of the study was to supply the demand prediction of housing market with useful information by identifying housing preferences as housing norms of family levels. The survey uses questionnaires which are delivered to the 329 households who live in more $66m^2$-less than $99m^2$(2 0pyoung) or more $99m^2$-less than $132m^2$(30 pyoung) multi-family dwellings in Ulsan. The frequency test, t-test, factor analysis and One-Way analysis were used for the analysis of the results. more than half of households have held house-moving plan within 3 years. most of them have desired to live at the high-rise apartment in Nam-Ku area and have wanted wide size through an average of $3.3m^2$(10 pyoung) than present house size. It was revealed that the characteristics of moving behaviors, residential areas and housing preferences were significant variables which affected to housing satisfaction.

• Journal of Family Resource Management and Policy Review
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• v.9 no.4
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• pp.81-93
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• 2005

The purpose of this study were to examine the time use of college students, and then to investigate the relationship between the satisfaction of the time use and the self identity. The subjects were 249 students in college. It was analyzed by using frequency, mean, ANOVA, Duncan's multiple range analysis. The results were as follows: 1. College students were used to employ many obligate time including studying. Their peak time was 10 a.m., 6 p.m. or 10 p.m., and their slump time was from 7 a.m. to 9, or from noon to 2 p.m.. They enjoyed on weekend, and then tired on Monday. 2. College students were satisfied with the future time use than the present. In survey of self-identity inventory, they lacked confidence in their future, but they oriented their goal and were familiar with the social network. 3. The more college students satisfied time use, the more the level of self-identity was high. This, it was suggested the program of time management for college students.

• Clinical and Experimental Reproductive Medicine
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• v.32 no.3
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• pp.269-277
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• 2005

Objectives: Previously, we sought to compile a list of genes expressed during early folliculogenesis by using cDNA microarray to investigate follicular gene expression and changes during primordialprimary follicle transition and development of secondary follicles (Yoon et al., 2005). Among those genes, a group of genes related to the cell size growth was characterized during the ovarian development in the present study. Methods: We determined ovarian expression pattern of six genes related to the cell size growth (cyr61, emp1, fhl1, socs2, wig1 and wisp1) and extended into CCN family (${\underline{c}}onnective$ tissue growth factor/${\underline{c}}ysteine$-rich 61/${\underline{n}}ephroblastoma$-overexpressed), ctgf, nov, wisp2, wisp3, including cyr61 and wisp1 genes. Expression of mRNA and protein according to the ovarian developmental stage was evaluated by in situ hybridization, and/or semiquantitative reverse transcriptase polymerase chain reaction (RT-PCR), and immunohistochemistry, respectively. Results: Among 6 genes related to the cell size growth, cyr61 and wisp1 mRNA was detected only in oocytes in the postnatal day5 mouse ovaries. cyr61 mRNA expression was limited to the nucleolus of oocytes, while wisp1 was expressed in the cytoplasm and nucleolus of oocytes, except nucleus. cyr61 mRNA expression, however, was found in granulosa cells from secondary follicles. The rest 4 genes in the cell size growth group were detected in oocytes, granulosa and theca cells. Cyr61 and Wisp1 proteins were expressed in the oocyte cytoplasm from primordial follicle stage. Especially, Cyr61 protein was detected in pre-granulosa cells, Wisp1 protein was not. By using RT-PCR, we evaluated and decided that Cyr61 protein is produced by their own mRNA in pre-granulosa cells that was not detected by in situ hybridization. cyr61 and wisp1 genes are happen to be the CCN family members. The other members of CCN family were also studied, but their expression was detected in oocytes, granulose and theca cells. Conclusions: We firstly characterized the ovarian expression of genes related to the cell size growth and CCN family according to the early folliculogenesis. Cyr61 protein expression in the pre-granulosa cells is profound in meaning. Further functional analysis for cyr61 in early folliculogenesis is under investigation.

• Journal of Preventive Medicine and Public Health
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• v.31 no.2 s.61
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• pp.310-322
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• 1998

In order to reinforce the role of primary care physician and o improve doctor-patient relationship, the Korean government tried to introduce 'Family Doctor Registration Program' into Seocho-Gu in Seoul, Ansung-Gun and Paju city in Kyunggi-Do in Oct. 1996. Community residents and doctors in those area did not show much interest in this project because of low incentives. We have done this study to see how much people know 'Family Doctor Registration Program' and what is people's real needs about 'Family Doctor Registration Program'. We selected 1,800 telephone numbers in Seoul, Chongju city, and Ansung-Gun by multi-stage stratified random sampling. Three trained survey personnels called them and got answers to the premade questionnaire until they completed the questionnaires of 200 persons in each community. The calling time was 7-9 p.m. from Monday to Friday, 3-9 p.m. on Saturday, and 9 a.m. to 9 p.m. on Sunday. We dropped out the persons who did not respond 3 times. The subjects consisted of 222 male and 367 female residents. Their ages ranged from 20 to 78: 24.8% in their 30s, 23.4% in their 20s, 22.5% in their 40s in male, and 35.2% in theirs, 22.5% in their 40s, 18.5% in their 20s in female. 9.9% of male and 13.2 % of female had their Family Doctors. The specialties of their Family Doctors were internists in 56.2%, general surgeons in 11.0%. The persons who did not have their family doctors were asked which doctors they would prefer if they had choices of family doctor. The results were internists in 50.3%, family physicians in 13.0%, pediatricians in 4.8%. Only 16.0% residents knew that government tried to introduce Family Doctor Registration Program. The 'Family Doctor Registration Program' was not well known to people. The results of our study showed that more effective incentives and public notifications are needed to activate this program.

• Journal of the Korean Home Economics Association
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• v.38 no.10
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• pp.1-14
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• 2000

This study was to identify the influence of family adaptability and cohesion on marriage satisfaction and distress of married couples. For the data 434 married couples Living in Pusan, Korea were chosen. The data were analyzed using M, SD, t-test, factor analysis, MANOVA, scheffe-test, Pearson's correlation, multiple regression, and path analysis. The findings of this study are as follows; First, marital satisfaction is higher for husbands than wives. Physical and psychological distress are higher for wives than husbands. Second, married couples who perceived family adaptability to be higher level are higher marital satisfaction. And husbands who perceived family adaptability to be higher bevel are higher physical distress than other levels of adaptability. Third, husbands who perceived family cohesion to be higher level are higher marital satisfaction, and are lower psychological and physical distress than other levels of adaptability. Wives who perceived family cohesion to be higher level are higher marital satisfaction, and are lower psychological distress than other levels of adaptability. Fourth, for husbands, family adaptability, cohesion and marital satisfaction have significant direct effect on psychological and physical distress. Besides, family cohesion are indirectly associated with psychological and physical distress For wives, family cohesion and marital satisfaction have significant direct effect on psychological distress. Besides, family cohesion are indirectly associated with psychological and physical distress.

• Natural Product Sciences
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• v.23 no.4
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• pp.227-234
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• 2017

Moringa oleifera Lam (M. oleifera, Moringaceae) is a tree of the Moringaceae family that can reach a height of between 5 and 10 m. The current paper presents cytotoxic effect of M. oleifera fruits and its flavonoids 1 and 2. The viability of HCT116 human colon cancer cells were 38.5% reduced by $150{\mu}g/mL$ of ethanolic extracts in a concentration-dependent manner; in addition, we observed the apoptotic features of cell shrinkage and decreased cell size. Bcl-2 family proteins were regulated as determined by Western blotting analysis, suggesting that M. oleifera fruits and their flavonoids 1 and 2 induced apoptosis through an intrinsic pathway. Based on our findings, 70% ethanolic extracts of M. oleifera fruits and flavonoids 1 and 2 might be useful as cytotoxic agents in colorectal cancer therapy.

• Journal of Integrative Natural Science
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• v.3 no.2
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• pp.72-77
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• 2010

Alginate lyases, also known as alginases or alginate depolymerases, catalyze the degradation of alginate by a ${\beta}$-elimination mechanism that has yet to be fully elucidated. Alginate is a copolymer of ${\alpha}$-L-guluronate (G) and its C5 epimer ${\beta}$-D-mannuronate (M), arranged as homopolymeric G blocks, M blocks, alternating GM or random heteropolymeric G/M stretches. Almost all alginate lyases depolymerize alginate in an endolytical fashion via a ${\beta}$-elimination reaction. The alginate lyase Atu3025 from Agrobacterium tumefaciens strain C58, consisting of 776 amino-acid residues, is a novel exotype alginate lyase classified into polysaccharide lyase family 15. Till now there is no crystal structure available for this class of proteins. Since there is no template with high sequence identity, three-dimensional coordinates for exotype alginate lyase (PL 15 family) were determined using modeling methods (Comparitive modeling and Fold recognition). The structures were modeled using the X-ray coordinates from Heparinase protein family (PDB code: 3E7J). This enzyme (Atu3025) displays enzymatic activity for both poly-M and poly-G alginate. Since poly-M is widespread; docking of a tri-mannuronate against the modeled structure was performed. We identified some of those residues which are crucial for lyase activity. The results from this study should guide future mutagenesis studies and also provides a starting point for further proceedings.