• Asian Pacific Journal of Cancer Prevention
• /
• 제13권4호
• /
• pp.1519-1524
• /
• 2012

Background: Human papillomavirus (HPV) infection is the main cause of cervical cancer. Limited epidemiologic data of HPV prevalence are available for women attending hospitals in southern China. This study aimed to evaluate the profiles of HPV infection and cytology status in gynecological outpatients in Chaozhou City. Methods: A total of 2833 eligible women were enrolled. The HPV GenoArray test was used for HPV detection and genotyping. Nearly one half of the HPV positive women received liquid-based cytology test. Logistic regression analysis was performed to assess the predictable effects of age and genotype for categories of abnormal cytology. Results: The prevalence of overall, high-risk, and low-risk HPV infection were 24.5%, 19.5% and 8.4%, respectively. A U-shaped age-specific prevalence curve was observed in overall HPV and high-risk HPV, but not in low-risk HPV, which declined with age increasing. The 6 most common high-risk HPV type in descending order, were types 52, 16, 58, 18, 68, and 33. Age and HPV genotype were both important determinants of abnormal cytology incidence, the older women (>45 years) and those infected with HPV type 16 and/or 18 having the highest risk for abnormal cytology. Conclusion: Our findings support the hypothesis that second-generation HPV prophylactic vaccines including HPV-52 and -58 may offer higher protection for women residing in Chaozhou and neighboring cities in Guangdong.

• 대한임상검사과학회지
• /
• 제46권3호
• /
• pp.91-98
• /
• 2014

Primary gastric lymphoma (PGL) is derived from mucosa-associated lymphoid tissue (MALT) and it differs from nodal lymphoma in histologic features and biologic behavior. Recent studies have showed that Helicobacter pylori (H.pylori ) infection is closely related to the development of low grade gastric lymphoma, and eradication of the infection induces regression of the tumor. H. pylori infection is known to be important to the development of gastric MALT lymphoma. The aim of this study was to elucidate the histopathological behavior of PGL according to the concept of MALT and to compare the predictive value of tests frequently used for diagnosis of H. pylori. The histological features of gastric lymphoma arising from MALT are the replacement of glands by uniform dense infiltration of centrocyte-like cells in the lamina propria and lymphoidepithelial lesion. H. pylori-associated histologic changes of neutrophilic infiltration, lymphoid follicle or aggregates formation and intestinal metaplasia, and H. pylori immunoreactivity were analyzed. Detection of H. pylori in chronic active gastritis and peptic ulcer suggests a possible role of H. pylori in the pathogenesis. Giemsa, Toluidine blue and Long H&E stains were used in H. pylori detection. Histopathological examination of gastric biopsy specimens revealed lymphoepithelial lesions pathognomonic of MALT lymphoma, and immunohistochemical staining for CD20 was diffusely positive. CD3 was positive in reactive T cells. PAX-5 was negative except the follicle. Bcl-2, cytokeratin, Ki-67, and c-myc were positive. The findings may indicate a predictable transition of low grade to high grade, and c-myc may be used as a valuable marker before molecular pathology diagnosis.

• Journal of Audiology & Otology
• /
• 제24권2호
• /
• pp.85-90
• /
• 2020

Background and Objectives: The present study aimed to compare thresholds of direct bone-conduction (BC direct) with those of behaviorally measured BC pure-tone audiometry (PTA) and objectively measured BC auditory brainstem response (ABR) to confirm the clinical feasibility of their relationships. Subjects and Methods: Young adults with normal hearing participated in the study to determine the thresholds from three measurements at four testing frequencies. In the BC direct, the vibrator of a bone-anchored hearing aid softband was placed on the right mastoid of each subject. In both PTA and ABR, a B71 bone oscillator was placed on the subject's right mastoid. While the subject's thresholds of BC direct and BC PTA were determined with a clinically routine 5-dB step procedure, BC ABR was conducted to determine the individual's hearing sensitivity by a peak V of the waveform using tone-burst and click stimuli. Results: The BC direct showed a different pattern between low and high frequencies. Precisely, its thresholds were 13.25 and 12.25 dB HL at 0.5 and 1 kHz, respectively, but 19 and 19.75 dB HL at 2 and 4 kHz, respectively. A significant positive correlation existed between BC direct and PTA at 1 kHz, which was also correlated with ABR. Conclusions: Based on the current data, the thresholds of BC direct were similar to BC PTA at low frequencies and BC ABR at high frequencies. The thresholds of BC direct might be predictable at approximately 5 dB higher (or lower) than that in PTA, although a large data set is required for standardization.

• 대한청각학회지
• /
• 제24권2호
• /
• pp.85-90
• /
• 2020

Background and Objectives: The present study aimed to compare thresholds of direct bone-conduction (BC direct) with those of behaviorally measured BC pure-tone audiometry (PTA) and objectively measured BC auditory brainstem response (ABR) to confirm the clinical feasibility of their relationships. Subjects and Methods: Young adults with normal hearing participated in the study to determine the thresholds from three measurements at four testing frequencies. In the BC direct, the vibrator of a bone-anchored hearing aid softband was placed on the right mastoid of each subject. In both PTA and ABR, a B71 bone oscillator was placed on the subject's right mastoid. While the subject's thresholds of BC direct and BC PTA were determined with a clinically routine 5-dB step procedure, BC ABR was conducted to determine the individual's hearing sensitivity by a peak V of the waveform using tone-burst and click stimuli. Results: The BC direct showed a different pattern between low and high frequencies. Precisely, its thresholds were 13.25 and 12.25 dB HL at 0.5 and 1 kHz, respectively, but 19 and 19.75 dB HL at 2 and 4 kHz, respectively. A significant positive correlation existed between BC direct and PTA at 1 kHz, which was also correlated with ABR. Conclusions: Based on the current data, the thresholds of BC direct were similar to BC PTA at low frequencies and BC ABR at high frequencies. The thresholds of BC direct might be predictable at approximately 5 dB higher (or lower) than that in PTA, although a large data set is required for standardization.

• 대한토목학회논문집
• /
• 제42권2호
• /
• pp.257-261
• /
• 2022

건축물의 디자인 자유도 향상, 작업자 안전 향상, 비교적 쉬운 납기예측 등의 이점으로 건설 산업에 적용된 3D 프린팅 기술(Additive manufacturing, AM)은 각종 효과성의 검증과 산업적용이 진행되고 있다. 다만, 기존기술대비 낮은 성숙도로 인해, 건축AM기술의 전주기에 발생하는 새로운 문제들을 해소하기 위한 연구들이 진행 중이다. 본 논문에서는 이러한 문제점 중에서도 현장 환경에 건축물을 적층 시공하는 과정에서, 낮은 시공표면평탄이 적층 제조 형상물에 미치는 영향을 확인한다. 특히 레이저 스캐닝을 통한 3차원 재구성 및 정량 분석을 통해, 낮은 평탄도로 인한 불균일한 적층형상물을 분석하고, 이를 해소하기 위한 적층시공전략을 제안한다.

• 한국항행학회논문지
• /
• 제27권6호
• /
• pp.710-715
• /
• 2023

도시화가 가속화되면서 교통 혼잡, 주거 및 환경 문제 등의 사회적 이슈가 도출되고 있다. 이를 해결하기 위해 도심항공교통 (UAM; urban air mobility)과 같은 혁신적인 교통시스템 개발에 관한 연구가 활발하게 진행되고 있다. 초기 저밀도 운항 환경에서 기존의 항공교통시스템에 부담을 주지 않으면서도 안전하게 비행이 이루어져야 하고, 공역을 효율적으로 관리하고 운영하는 능력이 요구된다. 따라서 UAM은 회랑을 통한 경로의 운영으로 예측 가능성을 높여 초기 운영단계에서는 저밀도 상황에서의 운항에 대한 데이터를 축적해 나가는 것이 중요하다. 이를 위해서는 운영하기 전 각종 시뮬레이션을 활용한 시나리오를 생성하여 UAM 기체 간의 잠재적인 충돌 가능성을 예측하고 항공기 간격 즉 분리에 대한 손실 (LoS; loss of separation), 그리고 근접 공중충돌 (NMAC; near mid air collision) 위험에 대한 검토가 필요하다. 항적 난기류는 항공기 간의 안전한 분리를 보장하는 중요한 요소로, 기존 항공교통에서는 활주로와 항로의 분리에 필수적으로 사용되었다. UAM 비행체는 저고도에서 밀집된 공간에서 운영되기 때문에, 항적 난기류에 관한 추가적인 연구가 필요하며, 이를 위해 다양한 데이터를 활용하여 기체의 성능을 정밀하게 분석하고 있다. 본 논문에서는 국내외 연구 결과를 바탕으로 UAM의 분리 기준 설정에 필요한 요구사항과 고려해야 할 사항들을 확인하는 데 초점을 맞추고자 한다.

• Maxillofacial Plastic and Reconstructive Surgery
• /
• 제31권3호
• /
• pp.254-261
• /
• 2009

저자들은 상악골 구치부에서 잔존 치조골의 흡수 및 상악동의 함기화로 인하여 통상적인 임플란트 시술이 어려운 증례에서 하악골의 하악지에서 자가골을 채취하여 이를 분쇄한 후 이종골과 부피비로 약1:1로 혼합하여 상악동 골이식술을 시행하고 동시에 임플란트를 식립하여 비교적 만족할만한 결과를 얻었기에 이를 문헌고찰과 함께 보고하며, 향후 이러한 증례들과 다른 골이식재를 사용한 증례들에 대하여 보다 장기적인 추적조사와 골이식된 부위의 골조직의 재형성, 식립된 임프란트의 보철적인 기능과 장기적인 예후에 대한 보다 체계적인 연구가 필요하리라 사료된다.

• Maxillofacial Plastic and Reconstructive Surgery
• /
• 제33권3호
• /
• pp.281-285
• /
• 2011

Sinus floor elevation is a predictable and standard procedure for the treatment of the posterior maxilla before insertion of dental implants. Although overall complication rates are low, complications can occur including sinus membrane perforation, infection of sinus, swelling and hemorrhage. The most common complication is membrane perforation. Recently, various techniques and materials for repair of perforation to the sinus membrane have been proposed. The purpose of this article is to report on various techniques and materials that can be used for repair of perforations to the sinus membrane. The search protocol used was the following electronic database: Pubmed, with a time limit from 1998 to 2009. The key words such as 'sinus lift', 'sinus augmentation', 'sinus floor elevation', 'sinus graft', 'sinus perforation', 'repair of sinus perforation' and 'repair of sinus membrane' were used, alone and in combination, when searching the database. Various techniques have been proposed to manage of perforation of sinus membranes. These include that the use of collagen membranes, demineralized freeze-dried human lamellar bone sheets, processed human allografts, lamella bone, buccal fat pads and suturing. Implant success rate ranges from 69.9% to 98.9%.

• Maxillofacial Plastic and Reconstructive Surgery
• /
• 제34권3호
• /
• pp.186-199
• /
• 2012

Purpose: Single implants, of which screw loosening has been observed frequently, presents problems such as fixtures fractures, marginal bone loss, and inflammation of the soft tissue around the implant. However, the single implant is more conservative, cost effective, and predictable compared to the 3 unit bridge with respect to the long-term outcome. This study evaluated the survival rate as well as future methods aimed at increasing the survival rate in single implants in posterior teeth. Methods: Among the implants placed in the Dankook University Dental Hospital department of Oral & Maxillofacial surgery from January 2001 to June 2008, 599 implants placed in the maxillar and mandibular posterior were evaluated retrospectively. Survival rates were investigated according to implant location, cause of tooth loss, gender, age, general disease, fixture diameter and length, surface texture, implant type and shape, presence of bone graft, surgery stage, surgeons, bone quality and opposite teeth. Results: Out of 599 single implants in posterior teeth, 580 implants survived and the survival rate was 96.8%. The difference in survival rate was statistically significant according to the implant location. The survival rate was low (84.2%) in implants exhibiting a wide diameter (${\geq}5.1mm$) and the surface treated by the acid etching group demonstrated a significantly lower survival rate (91.1%). One stage surgical procedure, which implemented a relatively better bone quality survival rate (100%), was higher than the two stage surgical procedure (96.1%). The survival rate of type IV bone quality (75%) was significantly lower than the other bone quality. Conclusion: Single posterior teeth implant treatments should use an improved surface finishing fixture as well as careful and safe procedures when performing implant surgery in the maxilla premolar and molar regions since bone quality is poor.

• 한국가스학회지
• /
• 제14권2호
• /
• pp.27-33
• /
• 2010

본 논문에서는 국내 가스사고의 발생 환경을 분석하여 가스사고의 재발을 방지하고자 1998년부터 2009년 6월까지 11년 6개월간의 가스사고를 유형별로 분석하였다. 가스사고는 감소하지 않고 지속적으로 발생하고 있고, 사고의 내용에서도 시기별, 날씨 등에 따라 가스사용형태가 변하고 있어 가스의 사용 환경과 가스사고는 밀접할 수밖에 없다. 가스사고는 가스사용이 많은 수도권과 특정 지자체에서 많이 발생하였고, 맑은 날 풍속이 낮고 습도가 중간정도일 때 가장 발생가능성이 높은 것으로 나타났다. 또한, 가스사고 발생 형태의 모형을 관찰한 결과, 가스로 인한 누출, 화재나 폭발 사고의 경우도 날씨와 밀접한 관계가 있을 것으로 판단되는데 이를 날씨와도 연계하여 분석해보면 발생 가능한 전체 가스사고도 예측 가능할 것으로 판단된다.