• Title/Summary/Keyword: low involvement

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Recent Update of Advanced Imaging for Diagnosis of Cardiac Sarcoidosis: Based on the Findings of Cardiac Magnetic Resonance Imaging and Positron Emission Tomography

  • Chang, Suyon;Lee, Won Woo;Chun, Eun Ju
    • Investigative Magnetic Resonance Imaging
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    • v.23 no.2
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    • pp.100-113
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    • 2019
  • Sarcoidosis is a multisystem disease characterized by noncaseating granulomas. Cardiac involvement is known to have poor prognosis because it can manifest as a serious condition such as the conduction abnormality, heart failure, ventricular arrhythmia, or sudden cardiac death. Although early diagnosis and early treatment is critical to improve patient prognosis, the diagnosis of CS is challenging in most cases. Diagnosis usually relies on endomyocardial biopsy (EMB), but its diagnostic yield is low due to the incidence of patchy myocardial involvement. Guidelines for the diagnosis of CS recommend a combination of clinical, electrocardiographic, and imaging findings from various modalities, if EMB cannot confirm the diagnosis. Especially, the role of advanced imaging such as cardiac magnetic resonance (CMR) imaging and positron emission tomography (PET), has shown to be important not only for the diagnosis, but also for monitoring treatment response and prognostication. CMR can evaluate cardiac function and fibrotic scar with good specificity. Late gadolinium enhancement (LGE) in CMR shows a distinctive enhancement pattern for each disease, which may be useful for differential diagnosis of CS from other similar diseases. Effectively, T1 or T2 mapping techniques can be also used for early recognition of CS. In the meantime, PET can detect and quantify metabolic activity and can be used to monitor treatment response. Recently, the use of a hybrid CMR-PET has introduced to allow identify patients with active CS with excellent co-localization and better diagnostic accuracy than CMR or PET alone. However, CS may show various findings with a wide spectrum, therefore, radiologists should consider the possible differential diagnosis of CS including myocarditis, dilated cardiomyopathy (DCM), hypertrophic cardiomyopathy, amyloidosis, and arrhythmogenic right ventricular cardiomyopathy. Radiologists should recognize the differences in various diseases that show the characteristics of mimicking CS, and try to get an accurate diagnosis of CS.

Upper Cervical Subluxation and Cervicomedullary Junction Compression in Patients with Rheumatoid Arthritis

  • Chung, Jaewoo;Bak, Koang Hum;Yi, Hyeong-Joong;Chun, Hyoung Joon;Ryu, Je Il;Han, Myung-Hoon
    • Journal of Korean Neurosurgical Society
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    • v.62 no.6
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    • pp.661-670
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    • 2019
  • Objective : Rheumatoid arthritis (RA) is known to involve the cervical spine up to 86%. It often causes cervical instability like atlantoaxial subluxation (AAS), subaxial subluxation, and vertical subluxation (VS). In order to find the relation between RA and cord compression, we will evaluate the characteristics and risk factors of basilar invagination (BI) and cervicomedullary junction (CMJ) compression. Methods : From January 2007 to May 2015, 12667 patients administrated to Hanyang University Medical Center. Four thousand three hundred eighty-six patients took cervical X-ray and 250 patients took cervical computed tomography or magnetic resonance imaging. Radiologic parameters, medication records were obtained from 242 patients. Multivariate logistic regression analysis was performed with correlation of CMJ compression, basin-dental interval (BDI), basin-posterior axial line interval (BAI), pannus formation, BI, and AAS. Results : In the point of CMJ compression, atlantodental interval (ADI), posterior-atlantodental interval, BAI, AAS, and BI are relatively highly correlated. Patients with BI have 82 times strong possibility of radiologic confirmed CMJ compression, while AAS has 6-fold and pannus formation has the 3-fold possibility. Compared to the low incidence of BI, AAS and pannus formation have more proportion in CMJ compression. Furthermore, wrist joint erosion was correlated with VS and AAS. Conclusion : BI has a very strong possibility of CMJ compression, while AAS and pannus formation have a high proportion in CMJ compression. Hence bilateral wrist joint erosion can be used as an indicator for the timing of screening test for cervical involvement. We suggest the early recommendation of cervical spine examination for the diagnosis of cervical involvement in order to prevent morbidity and mortality.

Cempedak Durian (Artocarpus sp.) Peel as a Biosorbent for the Removal of Toxic Methyl Violet 2B from Aqueous Solution

  • Dahri, Muhammad Khairud;Chieng, Hei Ing;Lim, Linda B.L.;Priyantha, Namal;Mei, Chan Chin
    • Korean Chemical Engineering Research
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    • v.53 no.5
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    • pp.576-583
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    • 2015
  • This paper aims to investigate the potential use of cempedak durian peel (CDP) from Negara Brunei Darussalam, which is low-cost, locally available, eco-friendly and highly efficient to remove methyl violet (MV) dye from aqueous solutions. The time required for equilibrium to be reached is 2.0 h with no adjustment of pH necessary. FTIR analysis was indicative of the involvement of -COOH and C=O functional groups in adsorption process. The Langmuir model provided the best fit with maximum adsorption capacity of $0.606mmol\;g^{-1}$. Thermodynamics data indicate that the adsorption is spontaneous, feasible and endothermic in nature. Best regeneration of CDP's adsorption ability is achieved by base solution, showing about 95% removal efficiency of MV even after 5 cycles, indicating that CDP can be regenerated and reused. This, together with its high adsorption capacity, makes CDP a potential adsorbent for the removal of MV in wastewater.

The Comparison of Verbal Behaviors in Cooperative Problem Solving Processes by Students' Previous Achievement Level (협동적인 문제 해결 과정에서 학생들의 사전 성취 수준에 따른 언어적 행동 비교)

  • Jeon, Kyung Moon;Yeo, Kyeong Hee;Noh, Tae Hee
    • Journal of the Korean Chemical Society
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    • v.44 no.4
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    • pp.356-362
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    • 2000
  • Students' protocols obtained from audio/video taping of small cooperative group problem solving processes were analyzed in the aspectsof verbal behaviors. The frequencies of the behaviors were com-pared by students' previous achievement level. Students' involvement in the verbal interaction for each level of students in each small group were also investigated. High-ability students ebility students and medium-or low-ability students.No significant differences were found in the subcategories of 'receiving information' or 'asking'. 0nly 3 small groups among 12 groups studied were found tobe bal-anced in students' involvelment. lnvolvement of medium-ability studentstended to be lower than that of high-and low-abilit students.

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Purification and characterization of a xylanase from alkalophilic cephalosporium sp. RYM-202

  • Kyu, Kang-Myoung;Kwon, Tae-Ik;Rhee, Yuung-Ha;Rhee, Young-Ha
    • Journal of Microbiology
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    • v.33 no.2
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    • pp.109-114
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    • 1995
  • Alkalophilic Cephalosporium sp. RYM-202 produced multiple xylanases extracellularly. One of these xylanases was purified to electrophoretical homogeneity by chromatography with DEAE-Sephadex A-50, Sephacryl S-200 HR and Superose 12 HR. The purified xylanase differed from most other microbial xylanases in that it had low-molecular weight and acidic isoelectric point. The molecular weight of the xylanase in that it had low-molecular weight and acidic isoelectric point. The molecular weight of the xylanase was 23 kDa by SDS-polyacrylamide electrophoresis and 24 kDa by gel permeation chromatography, and the isoelectric point was 4.3. The xylanase had the highest activity permentation chromatography, and the isoelectric point was 4.3. The xylanase had the highest activity permeation chromatography, and the isoelectric point was 4.3. The xylanase had the highest activity at pH 8.0 and 50 .deg.C. It was stable over a wide range of pH and retained more than 80% of its original activity after 24 h of incubation even at pH 12. The Km values of this enzyme on birchwood xylan and oat spelts xylan were 2.33 and 3.45 mg/ml, respectively. The complete inhibition of the enzyme of n-bromosuccinimide suggests the involvement of tryptophan in the active site. The sylanase lacked activity towards crystalline cellulose and carboxymethyl cellulose.

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Development of Health Behavior Assessment Tool of the Korean Elders (한국 노인의 건강행위 사정 도구 개발)

  • 최영희;김순이
    • Journal of Korean Academy of Nursing
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    • v.27 no.3
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    • pp.601-613
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    • 1997
  • This project was conducted using a survey method and through interviewing with four persons aged 60 years and over. An interview with an open-ended questionnaire was also used for elderly persons, families, oriental medicine doctor and nurses. topic-related literature review was also done. In total, 382 statements were derived. For content validity, nursing professionals were involved in this study, From that 48 items are developed. The subjects were 340 elderly persons over 60 years old. Data were collected duicing February and March 1997 and analyzed using the SPSS package The result are as follows. 1. Items with low Cronbach Coefficient alpha which means low correlation with total items were removed. 2. Factor analysis was done in order to confirm construct validity and eight factors were obtained from the results. The first factor, 'positive cognition of the aging process', the second factor, 'relationship network' the third factor, 'maintanence of physical functioning, the fourth factor', 'maintanence of peaceful mind' the fifth factor, 'keeping up with daily tasks' the sixth factor, 'continuous adequate body movement' the seventh factor,'involvement of religion in the elderly person's life and the eight factor', 'appropriate resting'. Cronbach Coefficient alpha for the 33 items was .9127 Based on the result, the following is suggested 1. It is anrticipated that the fundamental health of elderly person could be promoted by assessing healthy behaviors of elderly person with this assessment tool. 2. Further studies could be derived from this research. 3. Validity of this assessment tool should be further tested with and a larger sample of elderly person including in-patient elderly persons as well as nursing home residents.

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Chordoid Glioma Originating in the Intrasellar and Suprasellar Regions: Case Report

  • Hwang, Jisun;Lee, Aleum;Chang, Kee-Hyun;Moon, Ah Rim;Hwang, Sun-Chul;Hong, Hyun Sook
    • Investigative Magnetic Resonance Imaging
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    • v.19 no.2
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    • pp.117-121
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    • 2015
  • Chordoid glioma is a rare, low-grade brain neoplasm typically located in the third ventricle. Herein, we report an unusual case of histologically confirmed chordoid glioma located in the pituitary fossa and suprasellar region, not attached to the third ventricle. A 57-year-old woman presented with a 2-month history of headache and visual disturbance. Magnetic resonance imaging revealed an ovoid mass in the pituitary fossa and suprasellar region, compressing the optic chiasm without involvement of the third ventricle. The tumor showed low signal intensity on T1-weighted images and iso- to high signal intensity on T2-weighted images, with strong and homogenous contrast enhancement. Subtotal resection was performed via the transcranial approach, and the patient subsequently received adjuvant gamma knife radiosurgery. However, the residual mass showed disease progression 5 months after the initial surgery.

Involvement of NMDA Receptor and L-type Calcium Channel in the Excitatory Action of Morphine

  • Koo, Bon-Seop;Shin, Hong-Kee;Kang, Suk-Han;Jun, Jong-Hun
    • The Korean Journal of Physiology and Pharmacology
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    • v.6 no.5
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    • pp.241-246
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    • 2002
  • We studied the excitatory action of morphine on the responses of dorsal horn neuron to iontophoretic application of excitatory amino acid and C-fiber stimulation by using the in vivo electrophysiological technique in the rat. In 137 of the 232 wide dynamic range (WDR) neurons tested, iontophoretic application of morphine enhanced the WDR neuron responses to N-methyl-D-aspartate (NMDA), kainate, and graded electrical stimulation of C-fibers. Morphine did not have any excitatory effects on the responses of low threshold cells. Morphine-induced excitatory effect at low ejection current was naloxone-reversible and reversed to an inhibitory action at high ejection current. NMDA receptor, calcium channel and intracellular $Ca^{2+}$ antagonists strongly antagonized the morphine-induced excitatory effect. These results suggest that changes in intracellular ionic concentration, especially $Ca^{2+},$ play an important role in the induction of excitatory effect of morphine in the rat dorsal horn neurons.

Chemical Characteristics of Surface Soil and Mineral Content of Lawn in Some Golf Course in Kyonggi Province (경기도 수개 골프장의 표토 토양화학성과 잔디의 무기성분함량)

  • Choi, Byung-Ju;Shim, Jai-Sung;Ju, Yeong-Hee;Park, Hoon
    • Asian Journal of Turfgrass Science
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    • v.7 no.2_3
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    • pp.129-135
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    • 1993
  • Surface soils and aerial parts of Korean lawn(Zoysia koreana) at normal fair way of 4 golf courses and yellow discolored fairway of one golf course in Kyonggi province were taken at and analyzed for mineral contents in soil Mg and Ca were most deficient while EC was too high and phosphorus was exess. There were significant positive correlation between pH and Ca and between EC and total N. There was no consistent simple correlation between single component in soil and plant, indicating the involvement of multi-minerals in one mineral absorption. m mineral contents of aerial part Mg was severely low. potassium moderately but Ca was normal, Mg and Ca showed significant correlation in aerial part, yellow-discolored lawn showed the lowest content of Mg in aerial part and surface soil. Very high N and high phosphorus in aerial part inspite of low P in soil. The above facts indicates Mg deficiency in fair way soils in most golf courses resulting in yellow-discoloration in lawn.

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Status of Czech Low and Intermediate Radioactive Waste Management in the Context of European Development

  • Trtilek, Radek;Havlova, Vaclava;Podlaha, Josef;Svoboda, Karel;Otcovsky, Tomas
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.19 no.1
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    • pp.29-38
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    • 2021
  • The article summarises the status and competence of UJV Rez, a. s. (up to 2012, the Nuclear Research Institute Rez, Czech Republic) in the field of radioactive waste (RAW) management as a company managing of 95% of institutional radioactive wastes in Czech Republic. UJV Rez a. s. has been one of the Czech Republic's key research and engineering institutions in the field of nuclear energy production since 1955. The company processes and conditions prior to storage 95% of so-called institutional RAW and is the principal partner of the state with respect to the research support of the Czech deep geological repository development project. UJV Rez a. s. boasts its own accredited radiochemical analytical test laboratory, unique of its kind in the Czech Republic. Of equal importance is UJV Rez's active participation in a range of international organisations and associations and its involvement in wide range of international projects, and so as European projects. One of them is EU funded project PREDIS: Pre-disposal management of radioactive wastes, that has started at September 2020, focused on the field of low level radioactive waste (LLW) and intermediate level radioactive waste (ILW) pre-disposal.