The rice blast fungus, Magnaporthe oryzae, is an important pathogen of rice plants. It is well known that genes encoded in the genome have different evolutionary histories that are related to their functions. Phylostratigraphy is a method that correlates the evolutionary origin of genes with evolutionary transitions. Here we applied phylostratigraphy to partition total gene content of M. oryzae into distinct classes (phylostrata), which we designated PS1 to PS7, based on estimation of their emergence time. Genes in individual phylostrata did not show significant biases in their global distribution among seven chromosomes, but at the local level, clustering of genes belonging to the same phylostratum was observed. Our phylostrata-wide analysis of genes revealed that genes in the same phylostratum tend to be similar in many physical and functional characteristics such as gene length and structure, GC contents, codon adaptation index, and level of transcription, which correlates with biological functions in evolutionary context. We also found that a significant proportion of genes in the genome are orphans, for which no orthologs can be detected in the database. Among them, we narrowed down to seven orphan genes having transcriptional and translational evidences, and showed that one of them is implicated in asexual reproduction and virulence, suggesting ongoing evolution in this fungus through lineage-specific genes. Our results provide genomic basis for linking functions of pathogenicity factors and gene emergence time.
Recently, metal-composite hybrid structures became a very attractive material system for various applications such as automobile and air vehicles due to their design flexibility as well as superior mechanical properties. On the other hand, recycling is a hot issue to reduce material wastes and environmental pollution, so that many countries made recycling regulations. But the recycling of metal-composite hybrid structures is not fully considered since the development and application are very early stage. We developed and optimized the recycling process for metal-composite hybrid structures based on the easy adaptation of the local recycling companies.
Purpose: China's economy has changed considerably in recent decades. By delivering a comprehensive knowledge of the elements that support successful foreign direct investment (FDI) in China and practical insights for multinational firms operating in this dynamic environment, this research offers a new perspective and sets itself apart from previous studies. Research design, data and methodology: It is necessary to give a thorough overview of the body of information on successful FDI in China, which justifies the adoption of a systematic literature review. The study may use a wide range of studies because of this methodology, which guarantees that inferences have a solid and supported basis in data. Results: The findings in the present study have clarified how China's government policies and regulatory framework affect foreign direct investment (FDI). Previous studies have indicated that regulatory changes can significantly impact FDI. For instance, more foreign direct investment (FDI) has been drawn to liberalized industries such as technology and finance. Conclusions: In conclusion, for foreign direct investment (FDI) to be successful in China, it is essential to consider these four factors: local partnerships and cultural adaptation, market research and entry strategy, regulatory environment and policy support, and risk management and contingency planning.
Human activities greatly affect the environment causing its degradation. Urban development and road networks construction cause main impacts on ecosystems and particularly on vegetation cover: road constructions induce complete degradation of the vegetation cover and often leaves a hare land, sometimes without even a soil cover. Reconstitution of vegetation cover is necessary to limit superficial erosion and land slipping on the road, towards a reintegration of the site in the neighbouring landscape. Many approaches have been studied over the last 30 years aiming at this reconstitution of vegetation cover. At frost, the main purpose of land reclamation was to create a new ecosystem. At this time, the environment created was rather a "garden" with a new soil adapted to the plantation of "decorative" species. Then, in early 90′s many studies on the restoration ecology concept rather focused on adapting the vegetation to the existing conditions on the site, as in a side road embankment for example. Nowadays, we notice a large tendency towards the use of such adapted native species instead of industrially produced seeds. In southern France, our team have led research on the potentials of those local species for their use in revegetation processes with hydro-seeding. We therefore developed an approach combining the use of different types of species: Industrially produced, native and wild cultivated species. This method integrates the benefits of using available low costing seeds that are already used on large scale projects with better adapted species, issued form the cultivation of native species and seed production for their use on smaller scale and more costly but more effective results. The use of wild cultivated species seeds was developed in order to limit the cost and reduce harsh natural seed withdrawal in the natural environment In the case of the use of native species. Besides, the use of such seeds allowed a larger geographical scale of use than with local native seeds. In addition, our team began two years ago a research project in Lebanon aiming at the Introduction and development of the revegetation techniques in Lebanon. In fact, this country bared since 20 years the consequences of urban pressure on its environment especially by the development of quarries and road networks. Therefore, pioneer work is necessary to aim at the adaptation of these techniques to the local environment.
Kim, He-Jin;Ko, Sung-Back;Hong, Seong-Soo;Lee, Chang-Seop;Lee, Sang-Ho
Journal of the korean academy of Pediatric Dentistry
/
v.29
no.1
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pp.69-75
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2002
A number of techniques may be employed to reduce the discomfort of syringe or needle for dental care. The use of topical anesthesia is one such method. Topical anesthetics are applied to alleviate pain during many clinical procedures, such as injection of local infiltration anesthetics, primary tooth extraction, X-ray taking of sensitive patients, reducing gag reflex prior to impression taking. In children, placement of a rubber dam clamp, however, may cause significant discomfort for purpose of pit and fissure sealant and preventive resin restoration(PRR). A topical anesthetic would be beneficial to aid in rubber dam placement for this purpose. It has been suggested that all intra-oral topical anesthetics are equally effective on reflected mucosa, however EMLA(an acronym for eutectic mixture of local anesthetics), which was developed in the 1980s and produces surface anesthesia of skin, has been shown to be more effective than conventional topical anesthetics when used on attached gingivae. This report is topical anesthesized 4 case by EMLA cream, who showed better effect in reducing the pain of infiltration anesthesia, extraction of deciduous teeth, rubber dam clamp placement and reducing the pain of preformed crown adaptation.
To develop a new ginseng variety with good quality and high yielding, a lot of individual ginseng plant were selected in the farmers'fields in 1968. Among them, a promising line,680-83-4, has been developed through comparative cultivation of several lines selected with pure line separation from local races in KT&C Central Research Institute, preliminary and advanced yield trials were performed fir 8 years.680-83-4 was designated as KG103, which was then registered as a new variety “Gopoong” with the regional yield and adaptation trials for 10 years (1981-1990) on December 27,2000 in Korea. Gopoong has different phenotype of a dark violet stem and dark red fruit and inverted triangle shape of berries cluster as compared with other varieties. Taproot of Gopoong was longer than local race Jakyungjong, and root yield was 4.5% higher than local race Jakyungjong. In red ginseng quality, the rates of Chun-Jeesam grade(Chun and Jee means 1 st and 2nd grade, respectively) were 16.6% and 9.4% for Gopoong and Jakyungjong, respectively. In these results, it was that Gopoong was superior ginseng line with good quality far manufacture of red ginseng.
A possibility whether the appearance of adaptation to cold climate during winter could occur or not in Taegu area was evaluated by comparing the data obtained in winter with that obtained by the same method in summer. Circulatory response was induced by the immersion of one hand in the cold water. The systemic and local responses in the blood circulation from the immersed hand and the unimmersed opposite hand were observed simultaneously. In addition Galvanic skin resistance(GSR) that is influenced by the activity of autonomic nervous system and the vascular tonicity was recorded. The experiment was performed by examining sixty healthy college students in winter and fifty in summer, whose mean age was 21.0, mean weight $60.6{\pm}0.90\;kg(male)$ and $48.3{\pm}0.98\;kg(female)$. The cold stimulus was applied by immersing the left hand into the cold water of $5^{\circ}C$ for 3 minutes, and the response was observed on immersed left hand and unimmersed right hand simultaneously. The observation was made through determining mean blood pressure, heart rate, amplitude of photoelectric capillary pulse (APCP) and GSR. The results obtained are as follows: The mean blood pressure was elevated during the cold stimulation. The increase of blood pressure in summer was more remarkable than in winter. At the recovery period the blood pressure was decreased to the control level in winter but the decrease below the control level was observed in summer. The increase of heart rate in summer was more remarkable than in winter during the cold stimulation. At the recovery period heart rate in both winter and summer was decreased below the control level. During the cold stimulation the APCP was decreased on both hands in winter. However it was more prominent on left hand indicating additional direct cold effect on immersed hand. In summer, the decrease of APCP during immersion was less remarkable than that in winter, but the regain of APCP was faster than that in winter at the recovery period. And the prompt increase of APCP over the control level has been obtained at the 3 minutes of the recovery period. The GSR was remarkably increased on immersed hand but slightly decreased on unimmersed opposite hand during the cold stimulation. Thus the finding on immersed hand indicates that the local direct effect of cold water is more prominent than the systemic effect, where as the finding on unimmersed hand indicates that the circulatory response to painful stress elicited by the cold stimulation is more prominent than cold temperature itself. In summary, it seems that the systemic circulatory response to the local cold stimulation of the one hand is arised more from the secondary elicited pain sensation and less from the low water temperature. On the contrary to the report of Kim et $al^{39)}$, the adaptation phenomena in blood pressure to the relatively mild cold climate in winter was not observed in this study. The difference of circulatory response observed in this study between winter and summer may be due to the difference of the magnitude of subjective sensation of the cold water stimulation by the seasonal changes in air temperature.
This study has taken the Myeongjidong island, which has experienced spatial change due to various reasons ranging from the Japanese colonial era until today, as an instance in order to comprehend macroscopic spatial change of the Nakdonggang Delta and the adaptation process of the locals in a microscopic point of view. Spatial change of the Myeongjidong has been confirmed by collecting maps such as the atlas of late period of Chosun published in 1910, topographic map, regional geography, city records, and by applying coordinates with geographic reference function of GIS program, then checking for time sequential space change of individual regions. Space change driven by the Japanese government-general of Korea, Gimhae Irrigation Association, and by national policy or planning brought about environmental and humanistic changes unlike ever before, and land usage, housing and industry of the region and the locals experienced various adaptation processes. Such processes were compiled through collection and comparison of literature, and supplementation from interview of the locals during field study. As for the research region, it ranged from the construction of Nakdonggang bank and Myeongji seawall of 1935, agricultural rural landscape formed after the area expansion project by Gimhae Irrigation Association in 1940, to landscape that are becoming mercantile and urban due to the developmental plans of national and local governments.
Journal of the Korean Institute of Telematics and Electronics C
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v.35C
no.12
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pp.85-98
/
1998
This paper proposes a new design method of neuro-FLC by the Lamarckian co-adaptation scheme that incorporates the backpropagation learning into the GA evolution in an attempt to find optimal design parameters (fuzzy rule base and membership functions) of application-specific FLC. The design parameters are determined by evolution and learning in a way that the evolution performs the global search and makes inter-FLC parameter adjustments in order to obtain both the optimal rule base having high covering value and small number of useful fuzzy rules and the optimal membership functions having small approximation error and good control performance while the learning performs the local search and makes intra-FLC parameter adjustments by interacting each FLC with its environment. The proposed co-adaptive design method produces better approximation ability because it includes the backpropagation learning in every generation of GA evolution, shows better control performance because the used COG defuzzifier computes the crisp value accurately, and requires small workspace because the optimization procedure of fuzzy rule base and membership functions is performed concurrently by an integrated fitness function on the same fuzzy partition. Simulation results show that the Lamarckian co-adapted FLC produces the most superior one among the differently generated FLCs in all aspects such as the number of fuzzy rules, the approximation ability, and the control performance.
Journal of Korean Society of Coastal and Ocean Engineers
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v.27
no.5
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pp.304-314
/
2015
We have reviewed the current status of coastal vulnerability index(CVI) to be guided into an appropriate CVI development for Korean coast and applied a methodology into the east coast of Korea to quantify coastal vulnerability by future sea_level rise. The CVIs reviewed includes USGS CVI, sea_level rise CVI, compound CVI, and multi scale CVI. The USGS CVI, expressed into the external forcing of sea_level rise, wave and tide, and adaptive capacity of morphology, erosion and slope, is adopted here for CVI quantification. The range of CVI is 1.826~22.361 with a mean of 7.085 for present condition and increases into 2.887~30.619 with a mean of 12.361 for the year of 2100(1 m sea_level rise). The index "VERY HIGH" is currently 8.57% of the coast and occupies 35.56% in 2100. The pattern of CVI change by sea_level rise is different to different local areas, and Gangneung, Yangyang and Goseong show the highest increase. The land use pattern in the "VERY HIGH" index is dominated by both human system of housing complex, road, cropland, etc, and natural system of sand, wetland, forestry, etc., which suggests existing land utilization should be reframed in the era of climate change. Though CVI approach is highly efficient to deal with a large set of climate scenarios entailed in climate impact assessment due to uncertainties, we also propose three_level assessment for the application of CVI methodology in the site specific adaptation such as first screening assessment by CVI, second scoping assessment by impact model, and final risk quantification with the result of impact model.
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