• Title/Summary/Keyword: lipid serum

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A Clinical Proterties on Nutrients Intake and Serum Concentration of Diabetic Subjects by Duration in Ansung Kyunggi-do (경기도 안성지역 당뇨병 환자의 유병기간에 따른 영양소 섭취 실태와 혈액성상의 임상적 특징)

  • 노숙령
    • Journal of Nutrition and Health
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    • v.30 no.10
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    • pp.1203-1210
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    • 1997
  • This study was performed from March to June 1994 in ANsung Medical Center. We investigated serum components of 78 diabetics in the center, in addition to the nutrient intake status and anthrophometric status of 60 diabetics among them. We separated the latter into 2 groups(ⅰ) less tan 5 years of diabetic duration and ⅱ) more than 6 years of diabetic duration) and analyzed the clinical characteristics of each group. The results are as follows : \circled1 The average ages of male and female subjects were 57.1 and 58.9 years, respectively. The average diabetic duration of male subjects was 4.8 years and that of female subjects was 5.9 . The major occupational field of both male and female subjects was agriculture(33.3%, 36.1%). 50% of male and 75% of female subject's monthly incomes were less than 600, 000 won and 75% of male and 94.4% of female subjects had weekly food expense less than 40, 000 won. The nutrient intake status of the subjects was lower than RDA on the whole. There was no big differences between 2 the male groups of different diabetic duration , but calorie, protein , fat carbohydrate, phosphorus, iron and Vit B$_1$intakes of the above 6 year female group were appearently higher than those of the under 5 year female group (p<0.05). There were different intake tendencies between male and female subjects . For females. the longer the diabetic duration, the less intakes of calorie, protein , fat carbohydrate, phosphorus, iron Vit B$_1$, Vit B$_2$, and niacin were observed. Furthermore, the longer the diabetic duration in females , the more intakes of energy and nutrients, except Vit C were observed. Fasting blood glucose levels were 155mg/dl and 164mg/dl and Postprandial glucose levels were 242mg/dl and 247mg/dl for males and females respectively. Hb of both males and females , and Ht of males met the lower limit of normal status, The serum TG level was higher than normal , so that they seemed to suffer from hyperlipidemia ; their high HbAIC status indicated that the management of diabetes mellitus was poor. The total protein level of female subject was higher when compared with that of males(p<0.05). All subjects blood pressure were higher than normal , and the longer the diabetic duration, the higher was the blood pressure. The serum HDL-cholesterol levels of the above 6 year group male subjects were lower(p<0.05) than those of the under 5 year male group subjects, and the former group's systolic and diastolic blood pressures were higher than those of the latter(p<0.05). Levels of serum total protein, albumin and TG of the above 6 year female group were lower than those of the under 5 year female group(p<0.05). As the diabetic duration was extended, HDL-cholesterol and LDL-cholesterol levels showed a tendency to increase, while Hb, Ht, total protein, albumin, and A/G, which represent the nutrients state of iron and protein, were inclined to decrease. This result showed that serum lipid components went bad. To summarize the results, the longer the diabetic duration, the worse were the male subjects nutrient intake status, but those of the female subjects were good. With respect to serum components and serum lipid subjects Fe, protein, nutrition status and serum lipid component got worse as the diabetic duration was extended , implying the possibility of diabetes mellitus complication grows.

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Effect of Persimmon Vinegar on Serum Lipid Profile in Rats with High Cholesterol Diet (감식초가 고콜레스테롤 식이를 한 흰쥐의 혈중 지질 성분에 미치는 영향)

  • 정소형;김주현;정용진;최미자
    • Journal of the East Asian Society of Dietary Life
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    • v.9 no.4
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    • pp.421-426
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    • 1999
  • This study was performed to evaluate the effect of persimmon vinegar on serum lipid components in the hypercholesterolemic Sprague-Dawley male rats. Forty rats were divided into four groups and fed diets containing l% cholesterol for 4 weeks. Experimental diets added to distilled water, 1.5%, 3%, and 7% persimmon vinegar(PV) as drinking water. Concentration of total cholesterol, LDL and HDL cholesterol, triglyceride in serum and activity of AST, ALT in serum were assayed. Average food intake, weight gain and FER of experimental rats were not significantly different by contents of persimmon vinegar. Concentration of total cholesterol and LDL cholesterol in serum were lowest in 7% persimmon vinegar group. However concentration of HDL cholesterol in serum was highest in 3% persimmon vinegar group. Concentration of triglyceride in serum was significantly lower in persimmon vinegar group than control group. Activities of AST and ALT in serum were lowest in 7% persimmon vinegar group. The results in this study suggest that persimmon vinegar is effective in lowering serum triglyceride level.

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Effect of Vitamin E and Selenium on the Lipid Composition in Serum and Liver of Rats (비타민E와 셀렌이 흰쥐의 혈청(血淸) 및 간장(肝臟)중의 지질성분(脂質成分)에 미치는 영향(影禦))

  • Kim, Seun-Yeung;Cho, Soo-Yeul
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.14 no.1
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    • pp.33-38
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    • 1985
  • This experiment was undertaken to investigate ana to compare the effect of vitamin E and selenium on the lipid composition in serum and liver of rats. Net weight gain and food efficiency ratio were elevated by supplementation with selenium and/or vitamin E. The weight of kidney, heart and lung were not affected by the diets. However, liver weight was slightly decreased by supplementation with vitamin E and/or selenium and spleen weight was significantly decreased only by vitamin I supplementation. No differences in serum level of total lipid were found in all groups. Serum cholesterol level was significantly decreased, but the levels of triglyceride and free fatty acid in serum were increased by vitamin E supplementation. Contents of crude lipid, cholesterol, free fatty acid, and triglyceride in liver were significantly decreased by supplementation with vitamin E and/or selenium. In fatty aicd composition of liver, the percentage of linoleic acid(18:2) was the lowest in the selenium-Supplemented group and the significantly lower percentage of arachidonic acid(20:4) was found in the vitamin E and/or selenium-supplemented group in comparision to the deficient basal group.

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Effect of Calcium and Magnesium on the Lipid and Mineral Composition of Serum and Tissues in Cholesterol-fed Rats (칼슘과 마그네슘이 콜레스테롤 첨가식이로 사육한 흰쥐의 혈청과 조직중 지질 및 무기질에 미치는 영향)

  • Chang, Soon-Hee;Cho, Soo-Yeul;Park, Mi-Lee
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.17 no.2
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    • pp.176-183
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    • 1988
  • This experiment was undertaken to investigate the effect of caluium and magnesium on the lipid and mineral composition of serum and tissues in cholesterol-fed rats. GOT of serum was significantly decreased in normal Ca and high Mg supplemented group. Serum cholesterol level was significantly decreased in high Mg supplemented group, whereas that of low Mg supplemented group was significantly increased. Content of total lipid in liver were significantly decreased by supplementation with high calcium of magnesium. However, the content of cholesterol was not affected by supplementation with high calcim and that of low Mg supplemented group was significantly increased. In fatty acid composition of liver, he the order of fatty acid content is as following; oleic acid (18:1), stearic acid(18:0), and palmitic acid(16:0). Levels of Ca, Mg, K and Cu in liver were significantly affected by dietary calcium and magnesium levels. The Mg level of kidney was decreased but Cu level was elevated in cholesterol supplemented group. Levels of Ca, Mg, and Zn in serum were significantly elevated by supplementation with high calcium or magnesium.

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Supplementary Effect of the Giant Embryonic Rice on Serum and Heaptic Lipid Levels of Streptozotocin-induced Diabetic Rats (Streptozotocin 유발 당뇨 쥐의 거대배아미 식이에 의한 혈액 및 간조직의 지질조성)

  • Lee, Youn-Ri;Kim, Chae-Eun;Nam, Seok-Hyun;Kang, Mi-Young
    • Korean Journal of Food Science and Technology
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    • v.38 no.4
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    • pp.562-566
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    • 2006
  • This study was carried out to investigate the supplementary effects of giant embryonic rice, which has over two times of embryo size compared the normal rice, on lipid metabolism of insulin dependent diabetic rats. Streptozotocin induced diabetic rats were fed four kinds of experimental diets com starch diet as a control (C-D), a polished rice diet (R-D), a brown rice diet (BR-D) and a giant embryonic rice diet (GER-D) respectively, for 6 weeks. Diet intake body weight, organ weights and lipid levels of serum, liver and feces were measured. There was significant difference in diet intake and body weight among experimental groups. The concentrations of serum triglyceride and total serum cholesterol of BR-D and GER-D groups were lower than those of others. The total hepatic cholesterol level was the lowest in GER-D group. The contents of total lipid and total cholesterol excreted in feces of BR-D and GER-D groups were higher than those of C-D and R-D groups. These results suggested the giant embryonic rice diets can effectively reduce serum triglyceride level and total hepatic cholesterol level in insulin dependent diabetic rats, and hypolipidemic effects be due to increasing fecal lipid excretion.

Effect of Mycelium of Cordyceps militaris on Growth, Lipid Metabolism and Protein Levels in Male Rats (동충하초 균사체가 흰쥐의 성장률, 지질대사 및 단백질 농도에 미치는 영향)

  • Koh, Jin-Bog
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.31 no.4
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    • pp.685-690
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    • 2002
  • The effects of mycelium of Cordyceps militaris on the growth, the lipid metabolism, the serum protein levels and the enzyme activities in male rats were studied. Sprague-Dawley rats were given four different types of diets for a succeeding period of five weeks: either a control diet, a control diet supplemented with 2%, 3% or 4% mycelium of Cordyceps militaris (CM) powder. The body weight gain, hepatic weight, feed efficiency ratio and the feed intake of the rats given diets with 2%, 3% or 4% CM were similar to those in rats given the control diet. The concentrations of hepatic total lipid and triglyceride of rats fed the 3% or 4% CM diets were significantly lower than those of rats fed the control diet. But the concentrations of hepatic total cholesterol and phospholipid of rats fed the all CM diets were similar to those of rats fed the control diet. The concentrations of total lipid, total cholesterol, triglyceride phospholipid, and the atherogenic index, and the activities of glutamic oxaloacetic transaminase and lactic dehydrogenase in serum of rats fed the all CM diets were significantly lower than those of rats fed the control diet. No differences were noted in the concentrations of HDL-cholesterol, LDL-cholesterol, total protein, albumin and creatinine, and the activities of glutamic pyruvic transaminase, ${\gamma}$ -glutamyltranspeptidase and alkaline phosphatase in the serum among the rats with on all the experimental diets. These results showed that the all CM diets feeding decreased the total cholesterol, the triglyceride, the phopholipid, and the atherogenic index in serum of rats.

Relationship Among Serum Lipid levels, Obesity and Blood Pressure in Health Examined Adult Women (건강검진 수진 성인 여성의 혈청지질과 비만 및 혈압과의 관련성)

  • Park, Sung-Kyeong;Cho, Young-Chae
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.14 no.9
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    • pp.4342-4348
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    • 2013
  • The present study was intended to reveal the relationships between serum lipid levels and various factors of obesity and blood pressure. The study subjects were 1,838 adult women measured at a mass health screening during the period from January through December, 2011. TC, TG, HDL-C, LDL-C, SBP, DBP, degree of obesity, body fat rate were measured and the relation between these obesity and blood pressure measurements to serum lipid levels were studied. As a results, TC, TG, LDL-C, body fat rate and degree of obesity increased linearly with advancing age. TC, TG and LDL-C increased linearly with increasing blood pressure, and these values were higher in hypertension group than that of normal group. TC, TG and SBP increased linearly with increasing degree of obesity, and these values were higher in obesity group than that of normal group. HDL-C decreased linearly with increasing degree of obesity, and these values were lower in obesity group than that of normal group. TC, TG, HDL-C, degree of obesity, body fat rate was positive correlation with each others, but these values negatively correlated to HDL-C. Principal component analysis, showed that subjects could be divided into the group having the hypertensive group(1st principal component), the obesity group(2nd principal component), the hyperlipidemia group(3rd principal component), and HDL-C(4th principal component). In multiple regression analysis, age, TC, TG and body fat rate were affected to HDL-C. Above results suggest that higher the degree of obesity and blood pressure, the higher the serum lipid levels.

Effect of Recombinant Porcine Somatotropin(rPST) Administration on Pig Health (유전공학 Porcine Somatotropin의 투여가 돼지의 건강에 미치는 영향)

  • Lee Chang-Woo;Bak Ung-Bok;Chang Byoung-Sun;Kim Nam-Joong;Lee Byung-Gueon
    • Journal of Veterinary Clinics
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    • v.9 no.1
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    • pp.333-366
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    • 1992
  • Safety of recombinant porcine somatotropin administration on pig was studied using 32 Landrace x Yorkshire crossbred pigs. The starting body weight ranged from 55.5kg to 65.3kg. Eight pigs were allotted to each low dose group of sustained releasing rPST(SL), high dose group of sustained releasing rPST(SH), daily injection group of rPST(DI), and control group(C). Pigs in SL group and SH group were injected subcutaneously twice in 3 week-interval with 1000$\mu\textrm{g}$ and 2000$\mu\textrm{g}$ of sustained releasing rPST per kg body weight, respectively. Pigs in DI group were injected intramuscularly with 100$\mu\textrm{g}$ of rPST everyday for 6 weeks. Blood was collected from anterior vena cava just before the first treatment, and at four weeks and six weeks of experiment. Hematological parameters and blood chemical parameters indicating liver function, kidney function, electrolyte metabolism, mineral metabolism and lipid metabolism were determined. Necropsy and urinalysis were performed after final blood collection. The results were summarized as follows, and it is concluded that rPST administration does not affect pig health negatively. 1. rPST administration did not affect kidney function as manisfested by BUN, creatinine and urinalysis. 2. rPST administration did not affect liver function as manisfested by total protein, albumin, serum AST activity serum ALT activity serum ALP activity, serum LDH activity, serum GGT activity and serum SDH activity. 3. rPST administration did not affect skeletal muscle, cardiac muscle and brain as manifasted by serum AST activity and serum LDH activity. 4. rPST administration increased blood glucose level within normal range. 5. rPST administration did not affect lipid metabolism as manisfested by triglyceride, cholesterol, and phospholipid concentrati on. 6. rPst administration dia not affect mineral metabolism as manisfested by calcium, phosphorus, magnesium and iron concentration. 7. rPST administration did not affect electrolyte metabolism as manisfested by Na, K, chloride concentration. 8. rPST administration did not affect erythrocyte count, leukocyte count, thrombocyte count, and plasma fibrinogen level.

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