• 제목/요약/키워드: linkage analysis

검색결과 1,282건 처리시간 0.025초

연관분석을 위한 베이지안 모형 선택: 상호상관성 변수를 중심으로 (Bayesian Model Selection for Linkage Analyses: Considering Collinear Predictors)

  • 서영주
    • 응용통계연구
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    • 제18권3호
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    • pp.533-541
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    • 2005
  • 본 저자는 앞선 연구에서 제안한 SSVS 방법을 이용하여 한 양적형질에 대한 연관분석에 있어, QTL에 가까이 있는 관련된 표지유전자들의 위치를 정하고자 한다. 본 논문에서는 QTL에 연관되어 있고 동시에 서로 연관되어 있는 몇 가지 표지유전자들을 대상으로 하는데, 이 유전자 좌위들의 i.b.d. 값들을 상호 상관이 있는 예측변수로서 고려하여, SSVS 방법으로 분석한다. 두개의 QTL에 강하게 연관되어 있는 표지유전자들 만을 동시에 고려한 분석의 결과, QTL에 가장 가까이 위치한 표지 유전자가 다른 유전자들보다 더 분명하게 양적형질과의 관련성을 보여주었다. SSVS를 이용한 상호 상관이 있는 표지 유전자들의 분석의 결과는 전통적인 다중회귀분석을 이용한 결과와 거의 일치했다. 본 모의실험을 바탕으로, 복합 양적형질에 대하여 서로 연관된 다중의 표지유전자들을 동시에 연관분석을 수행하는 데에 SSVS 방법이 상당히 유용하다고 결론 내린다.

Power of Variance Component Linkage Analysis to Identify Quantitative Trait Locus in Chickens

  • Park, Hee-Bok;Heo, Kang-Nyeong;Kang, Bo-Seok;Jo, Cheorun;Lee, Jun Heon
    • Journal of Animal Science and Technology
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    • 제55권2호
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    • pp.103-107
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    • 2013
  • A crucial first step in the planning of any scientific experiment is to evaluate an appropriate sample size to permit sufficient statistical power to detect the desired effect. In this study, we investigated the optimal sample size of quantitative trait locus (QTL) linkage analysis for simple random sibship samples in pedigreed chicken populations, under the variance component framework implemented in the genetic power calculator program. Using the program, we could compute the statistical power required to achieve given sample sizes in variance component linkage analysis in random sibship data. For simplicity, an additive model was taken into account. Power calculations were performed to relate sample size to heritability attributable to a QTL. Under the various assumptions, comparative power curves indicated that the power to detect QTL with the variance component method is highly affected by a function of the effect size of QTL. Hence, more power can be achievable for QTL with a larger effect. In addition, a marked improvement in power could be obtained by increasing the sibship size. Thus, the use of chickens is advantageous regarding the sampling unit issue, since desirable sibship size can be easily obtained compared with other domestic species.

한국, 중국, 일본의 1차 산업의 생산유발효과 비교 연구 (A Competitive Study on the Linkage Effects of Primary Industry among Korea, China and Japan)

  • 임지원;이상근
    • 한국산업정보학회논문지
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    • 제23권5호
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    • pp.103-118
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    • 2018
  • 본 논문은 세계산업연관표의 전후방연쇄효과를 이용하여 2000년부터 2014년까지의 한국, 중국, 일본의 1차 산업의 생산유발효과를 비교 분석하였다. 1차 산업의 산업영향력에 관한 연구는 활발히 진행되어 왔으나, 본 논문은 1차 산업 분야에 대한 한국, 중국, 일본의 산업연쇄효과의 차이에 대한 연구라는 점에서 의미가 있다. Fisher(1939)와 Clark(1957)의 1차 산업 분류에 따라 1차 산업을 농림축산업, 임업, 수산업, 광업으로 분류하였다. 분석방법으로는 세계산업연관표를 이용하여 한국, 중국, 일본 3국간 산업연관모형을 만든 후 비교분석하는 것이다. 본 연구의 결과에 따르면, 농림축산업, 광업은 한국, 중국, 일본 각 국가별로 전 후방 연쇄효과에 유의한 차이가 있었고 임업과 수산업의 경우 한국, 중국, 일본의 전 후방 연쇄효과에 부분적으로 유의한 차이가 있었다. 1차 산업의 산업의존도 변화를 4차 산업혁명의 시대에 산업의 전방연쇄효과와 후방연쇄효과를 IO 분석을 통해 각 국가별로 비교함으로서 향후 1차 산업이 나아가야할 방향을 제시하였다.

국립민족학박물관의 전시·교육·운영·지역연계프로그램에 관한 조사 연구 (A Study on the Exhibition·Education·Operation Regional Linkage Program of the National Museum of Ethnology)

  • 박진아;정아영;공순구
    • 한국실내디자인학회논문집
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    • 제23권5호
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    • pp.146-156
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    • 2014
  • This study investigated and analyzed the exhibition, education, operation, and regional linkage program around a case of the National Museum of Ethnology in Netherlands, Germany, Mexico, England, and Japan to suggest necessary directions when constructing the national museum of ethnology of Korea. Interview by visiting the site and email interview were conducted for the investigation and suggestions according to the analysis are as follows. 1) It is necessary for the exhibition program to suggest a comparison exhibition by continent, and to be specific, occupation, style of living, representational culture, religion and view of the world, relation of power, and development culture are essential for the culture contents. 2) The education program needs to be constructed based on the age and level, and specific education program was suggested in this study. 3) Managing library, restaurant, cafe, and museum shop is essential for the operation program, additional service operation was suggested to cover additional financial areas, and professional research workers and professor manpower are necessary. 4) The regional linkage program needs to be composed by considering special qualities of the country and region, and needs to satisfy the expected effect of the local community and local residents.

소기업의 기업간 전자적 연결 도입 의도에 관한 연구: 기대 가치와 거래 관계 특성의 관점 (Small Firms' Adoption Intention of Inter-Firm Electronic Linkages)

  • 이원준;강윤정;김길선
    • Asia pacific journal of information systems
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    • 제15권2호
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    • pp.171-193
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    • 2005
  • Small firms are considered as the last mile in electronic networks of business enterprises. Since small firms lack in their resources and capabilities for IT deployment, it seems a challenging project to make them electronically linked to their trading partners. This study aims to investigate the factors that influence the intent of small firms to adopt electronic linkage to their trading partners. This study considers the context where small firms already have transaction relationships with partner firms and where their adoption of electronic linkage may influence the nature and performance of the transactional relationships. This study considers the expected value of electronic linkage and the joint actions of the trading firms as the major factors. Its research model also includes traditional factors such as influences from the industry and the trading partner, the support of CEO, and the readiness of the trading partner. Based on the survey data from more than 1000 small firms, the present study performs regression analysis and finds that all but one factor are significant in explaining the variations in the adoption intention of small firms. The exception is the joint action, which is shown to decrease the intention. Based on the results, this study offers business and policy implications that would be useful to business managers and policy makers.

Empirical Study on Stereotype for Burner-Control Relationship of Four-Stove Gas Range for Koreans

  • Kee, Do-Hyung
    • 대한인간공학회지
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    • 제31권3호
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    • pp.463-467
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    • 2012
  • This study aims to empirically investigate population stereotype of burner-control linkage of four-stove gas range for Koreans. Background: The previous studies' results for gas range stereotypes were different depending upon methods adopted, i.e., whether using questionnaires, computer simulation or physical models. It is known that the physical model experiment should not be methodologically replaced by the computer simulation or paper-and-pencil tests. Stereotype of gas range for Koreans was surveyed based on questionnaires, but has not been dealt with by using physical models. Method: An experiment was conducted to investigate stereotype of four-burner gas range, in which 32 subjects participated and a real gas range available in the market was bought and used. Four types of burner-control linkage were used as independent variable, and reaction time as dependent variable. Results: ANOVA revealed that four types of burner-control linkage and subjects' gender were not significant on reaction time. Duncan's multiple range test showed that reaction times for type III was significantly lower than those for the other three types of burner-control linkage(${\alpha}$=0.05). Conclusion: It is concluded based on the results of this study that stereotype of gas range for Koreans is type III. This is in agreement with results of existing studies using questionnaire survey, while different from those based on physical models. Application: The results of this study would be useful as an ergonomic guideline when designing gas ranges or similar equipments for minimizing operation errors.

Automatic Linkage Model of Classification Systems Based on a Pretraining Language Model for Interconnecting Science and Technology with Job Information

  • Jeong, Hyun Ji;Jang, Gwangseon;Shin, Donggu;Kim, Tae Hyun
    • Journal of Information Science Theory and Practice
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    • 제10권spc호
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    • pp.39-45
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    • 2022
  • For national industrial development in the Fourth Industrial Revolution, it is necessary to provide researchers with appropriate job information. This can be achieved by interconnecting the National Science and Technology Standard Classification System used for management of research activity with the Korean Employment Classification of Occupations used for job information management. In the present study, an automatic linkage model of classification systems is introduced based on a pre-trained language model for interconnecting science and technology information with job information. We propose for the first time an automatic model for linkage of classification systems. Our model effectively maps similar classes between the National Science & Technology Standard Classification System and Korean Employment Classification of Occupations. Moreover, the model increases interconnection performance by considering hierarchical features of classification systems. Experimental results show that precision and recall of the proposed model are about 0.82 and 0.84, respectively.

복부수술환자의 간호진단, 간호중재, 간호결과 연계 데이터베이스 구축 (Construction of Linkage Database on Nursing Diagnoses, Interventions, Outcomes in Abdominal Surgery Patients)

  • 유형숙;지성애
    • 간호행정학회지
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    • 제7권3호
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    • pp.425-437
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    • 2001
  • This reserch was to develop database software in order to handle a lot of clinical nursing data with nursing diagnoses, related factors, defining characteristics, nursing interventions, nursing activities and nursing outcomes. MS Access2000 and SQL was selected to use a general purpose database logic with an efficiency. MS Visual Basic 6.0 was used to construct the circumstance of Graphic User Interface. The Linkage Database of abdominal surgery patients was constructed from the clinical data and questionnaire. This database system could add related factors, defining characteristics, nursing activities in the database and analyze the statistical results through Access query. In the final stage, end-users satisfaction analysis using 5 points Likert scale was dong with the response of using the database system. The accuracy/trustworthiness of the database system was verified with the highest average scores as 4.42 and also, the efficiency as 4.21, user friendly function as 4.1.

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랙-피니언 조향기구의 조향오차 최적설계 (Optimum Design for Reducing Steering Error of Rack-and-Pinion Steering Linkage)

  • 홍경진;최동훈
    • 한국자동차공학회논문집
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    • 제6권2호
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    • pp.43-53
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    • 1998
  • This paper addresses an optimization for reducing a steering error of a rack-and-pinion steering linkage with a MacPherson strut independent front suspension system. The length, orientations and inner joint positions of a tie-rod are selected as design variables and Ackerman geonetry, understeer effect, minimum turn radius, wheel alignment and packaging are considered as design constraints. Nonlinear kinematic analysis of the steering system is performed for calculating the values of cost and constraints, and Augmented Lagrange Multiplier(ALM) method is used for solving the constrained optinization problem. The optimization results show that the steering error are considerably reduced while satisfying all the constraints.

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유치원(幼稚園)과 국민학교(國民學校) 저학년(低學年) 건축(建築)의 연계성(連繫性)에 관(關)한 연구(硏究) (A Study on the Linkage between the Kindergarten and The Lower Level Elementary School Buildings)

  • 윤천근
    • 교육시설
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    • 제2권2호
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    • pp.51-64
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    • 1995
  • This study investigates possible of linkage between kindergarten infants and the lower level elementary school students so aims to take a triangular position which direction of architectural space plan. The results of the study are as follows: 1) The results of analysis which infants and lower level elementary school students' behavior and activity showed similar play patterns in space attitude, rule of space use, similar to satisfaction and kinds of play, the time required, groups scale and place of play. 2) Architectures of kindergarten and lower level elementary school can classify style of selfhelp-singleness, establishment as an annex-singleness, establishment as an annex-attachment and divides space of education, management, service and analogized kinds of necessary space. 3) Infants of four, five years old and six, seven years old(first, second elementary school students) are similar to physical, intellectual, emotional development and have special characters of successions so kindergarten and lower level elementary school buildings must be necessary for organic linkage and intergration.

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