• Title/Summary/Keyword: linear growth model

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Genome wide association study for growth in Pakistani dromedary camels using genotyping-by-sequencing

  • Sajida Sabahat;Asif Nadeem;Rudiger Brauning;Peter C. Thomson;Mehar S. Khatkar
    • Animal Bioscience
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    • v.36 no.7
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    • pp.1010-1021
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    • 2023
  • Objective: Growth performance and growth-related traits have a crucial role in livestock due to their influence on productivity. This genome-wide association study (GWAS) in Pakistani dromedary camels was conducted to identify single nucleotide polymorphisms (SNPs) associated with growth at specific camel ages, and for selected SNPs, to investigate in detail how their effects change with increasing camel age. This is the first GWAS conducted on dromedary camels in this region. Methods: Two Pakistani breeds, Marecha and Lassi, were selected for this study. A genotyping-by-sequencing method was used, and a total of 65,644 SNPs were identified. For GWAS, weight records data with several body weight traits, namely, birthweight, weaning weight, and weights of camels at 1, 2, 4, and 6 years of age were analysed by using model-based growth curve analysis. Age-specific weight data were analysed with a linear mixed model that included fixed effects of SNP genotype as well as sex. Results: Based on the q-value method for false discovery control, for Marecha camels, five SNPs at q<0.01 and 96 at q<0.05 were significantly associated with the weight traits considered, while three (q<0.01) and seven (q<0.05) SNP associations were identified for Lassi camels. Several candidate genes harbouring these SNP were discovered. Conclusion: These results will help to better understand the genetic architecture of growth including how these genes are expressed at different phases of their life. This will serve to lay the foundations for applied breeding programs of camels by allowing the genetic selection of superior animals.

Growth Model of Sowthistle (Ixeris dentata Nakai) Using Expolinear Function in a Closed-type Plant Production System (완전제어형 식물 생산 시스템에서 선형 지수 함수를 이용한 씀바귀의 생육 모델)

  • Cha, Mi-Kyung;Son, Jung-Eek;Cho, Young-Yeol
    • Horticultural Science & Technology
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    • v.32 no.2
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    • pp.165-170
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    • 2014
  • The objective of this study was to make growth and yield models of sowthistle (Ixeris dentata Nakai) by using an expolinear functional equation in a closed-type plant production system. The growth and yield of hydroponically-grown sowthistle were investigated under four different planting distances ($15{\times}10$, $15{\times}15$, $15{\times}20$, and $15{\times}25$ cm). Shoot dry weights per plant was the highest at $15{\times}25$ cm, but was the lowest at $15{\times}10$ cm. Shoot dry weights per area was the highest at $15{\times}15$ cm, but was the lowest at $15{\times}25$ cm. The optimum planting density and planting distance for yield of sowthistle were 44 plants/$m^2$ and $15{\times}15$ cm, respectively. Shoot dry weights per plant and per area were showed as an expolinear type functional equation. A linear relationship between shoot dry and fresh weights was observed to be linear regardless of the planting distance. Crop growth rate, relative growth rate and lost time in an expolinear functional equation showed quadratic function form. Radiation use efficiency of sowthistle was $4.3-6.1g{\cdot}MJ^{-1}$. The measured and estimated shoot dry weights showed a good agreement using days after transplanting as input data. It is concluded that the expolinear growth model can be a useful tool for quantifying the growth and yield of sowthistle in a closed-type plant production system.

Estimating Optimal Harvesting Production of Yellow Croaker Caught by Multiple Fisheries Using Hamiltonian Method (해밀토니안기법을 이용한 복수어업의 참조기 최적어획량 추정)

  • Nam, Jong-Oh;Sim, Seong-Hyun;Kwon, Oh-Min
    • The Journal of Fisheries Business Administration
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    • v.46 no.2
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    • pp.59-74
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    • 2015
  • This study aims to estimate optimal harvesting production, fishing efforts, and stock levels of yellow croaker caught by the offshore Stow Net and the offshore Gill Net fisheries using the current value Hamiltonian method and the surplus production model. As analyzing processes, firstly, this study uses the Gavaris general linear model to estimate standardized fishing efforts of yellow croaker caught by the above multiple fisheries. Secondly, this study applies the Clarke Yoshimoto Pooley(CY&P) model among the various exponential growth models to estimate intrinsic growth rate(r), environmental carrying capacity(K), and catchability coefficient(q) of yellow croaker which inhabits in offshore area of Korea. Thirdly, the study determines optimal harvesting production, fishing efforts, and stock levels of yellow croaker using the current value Hamiltonian method which is including average landing price of yellow croaker, average unit cost of fishing efforts, and social discount rate based on standard of the Korean Development Institute. Finally, this study tries sensitivity analysis to understand changes in optimal harvesting production, fishing efforts, and stock levels of yellow croaker caused by changes in economic and biological parameters. As results drawn by the current value Hamiltonian model, the optimal harvesting production, fishing efforts, and stock levels of yellow croaker caught by the multiple fisheries were estimated as 19,173 ton, 101,644 horse power, and 146,144 ton respectively. In addition, as results of sensitivity analysis, firstly, if the social discount rate and the average landing price of yellow croaker continuously increase, the optimal harvesting production of yellow croaker increases at decreasing rate and then finally slightly decreases due to decreases in stock levels of yellow croaker. Secondly, if the average unit cost of fishing efforts continuously increases, the optimal fishing efforts of the multiple fisheries decreases, but the optimal stock level of yellow croaker increases. The optimal harvest starts climbing and then continuously decreases due to increases in the average unit cost. Thirdly, when the intrinsic growth rate of yellow croaker increases, the optimal harvest, fishing efforts, and stock level all continuously increase. In conclusion, this study suggests that the optimal harvesting production and fishing efforts were much less than actual harvesting production(35,279 ton) and estimated standardized fishing efforts(175,512 horse power) in 2013. This result implies that yellow croaker has been overfished due to excessive fishing efforts. Efficient management and conservative policy on stock of yellow croaker need to be urgently implemented.

Application of single-step genomic evaluation using social genetic effect model for growth in pig

  • Hong, Joon Ki;Kim, Young Sin;Cho, Kyu Ho;Lee, Deuk Hwan;Min, Ye Jin;Cho, Eun Seok
    • Asian-Australasian Journal of Animal Sciences
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    • v.32 no.12
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    • pp.1836-1843
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    • 2019
  • Objective: Social genetic effects (SGE) are an important genetic component for growth, group productivity, and welfare in pigs. The present study was conducted to evaluate i) the feasibility of the single-step genomic best linear unbiased prediction (ssGBLUP) approach with the inclusion of SGE in the model in pigs, and ii) the changes in the contribution of heritable SGE to the phenotypic variance with different scaling ${\omega}$ constants for genomic relationships. Methods: The dataset included performance tested growth rate records (average daily gain) from 13,166 and 21,762 pigs Landrace (LR) and Yorkshire (YS), respectively. A total of 1,041 (LR) and 964 (YS) pigs were genotyped using the Illumina PorcineSNP60 v2 BeadChip panel. With the BLUPF90 software package, genetic parameters were estimated using a modified animal model for competitive traits. Giving a fixed weight to pedigree relationships (${\tau}:1$), several weights (${\omega}_{xx}$, 0.1 to 1.0; with a 0.1 interval) were scaled with the genomic relationship for best model fit with Akaike information criterion (AIC). Results: The genetic variances and total heritability estimates ($T^2$) were mostly higher with ssGBLUP than in the pedigree-based analysis. The model AIC value increased with any level of ${\omega}$ other than 0.6 and 0.5 in LR and YS, respectively, indicating the worse fit of those models. The theoretical accuracies of direct and social breeding value were increased by decreasing ${\omega}$ in both breeds, indicating the better accuracy of ${\omega}_{0.1}$ models. Therefore, the optimal values of ${\omega}$ to minimize AIC and to increase theoretical accuracy were 0.6 in LR and 0.5 in YS. Conclusion: In conclusion, single-step ssGBLUP model fitting SGE showed significant improvement in accuracy compared with the pedigree-based analysis method; therefore, it could be implemented in a pig population for genomic selection based on SGE, especially in South Korean populations, with appropriate further adjustment of tuning parameters for relationship matrices.

세라믹 필터를 장착한 생물반응기에서 Bacillus thuringiensis의 성장 특성 모델링

  • Gang, Byeong-Cheol;Jang, Ho-Nam
    • 한국생물공학회:학술대회논문집
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    • 2000.11a
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    • pp.233-236
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    • 2000
  • Bacillus thuringiensis (Bt) is the most widely used microbial insecticide in the biological control market. Cultivation of the microorganism to high cell densities offers potential for enhancing the rate of formation as well as the concentration of the desired products In the fermentation broths in bioreactor. With this objective, we developed the new bioreactor incorporating ceramic membrane module for the retention of cell mass. Cell yield and spore formation of Bacillus thuringiensis was improved markedly by adopting this new bioreactor based on glucose -limited feeding operation. It was possible to grow the cell and the heat-resistant spore to above $1.2\;{\times}\;10^{10}\;CFU/ml$ density. With glucose-limited operation, we studied the growth behavior of Bacillus thuringiensis during the cell retention culture. Linear growth of Bacillus thuringiensis was observed under glucose-limited culture, which matched well with simple mathematical model of cell retention culture.

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An Empirical Investigation on the Dynamic Relationships among the Critical Factors Influencing on the High-tech Cluster Formation and Its Sustainable Growth (첨단산업클러스터 형성요인들간의 인과관계분석)

  • Kwoun, Sung-Taeck;Kim, Sang-Wook
    • Korean System Dynamics Review
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    • v.7 no.2
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    • pp.133-148
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    • 2006
  • This study suggests a Causal Loop Diagram(CLD) of causality mechanism which are integrating matters of localization, networking, embeddedness & institutional thickness and collective learning. These five factors(localization, networking, embeddedness & institutional thickness, collective learning, innovative synergy) have been studied and proofed Also this study suggest a model of industry cluster based on holistic and global system thinking rather than local and linear thinking.

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Normal Mode Approach to the Stability Analysis of Rossby-Haurwitz Wave

  • Jeong, Hanbyeol;Cheong, Hyeong Bin
    • Journal of the Korean earth science society
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    • v.38 no.3
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    • pp.173-181
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    • 2017
  • The stability of the steady Rossby-Haurwitz wave (R-H wave) in the nondivergent barotropic model (NBM) on the sphere was investigated with the normal mode method. The linearized NBM equation with respect to the R-H wave was formulated into the eigenvalue-eigenvector problem consisting of the huge sparse matrix by expanding the variables with the spherical harmonic functions. It was shown that the definite threshold R-H wave amplitude for instability could be obtained by the normal mode method. It was revealed that some unstable modes were stationary, which tend to amplify without the time change of the spatial structure. The maximum growth rate of the most unstable mode turned out to be in almost linear proportion to the R-H wave amplitude. As a whole, the growth rate of the unstable mode was found to increase with the zonal- and total-wavenumber. The most unstable mode turned out to consist of more-than-one zonal wavenumber, and in some cases, the mode exhibited a discontinuity over the local domain of weak or vanishing flow. The normal mode method developed here could be readily extended to the basic state comprised of multiple zonalwavenumber components as far as the same total wavenumber is given.

The Impact of Foreign Direct Investment, Aid and Exports on Economic Growth in Vietnam

  • NGUYEN, Cung Huu
    • The Journal of Asian Finance, Economics and Business
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    • v.7 no.10
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    • pp.581-589
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    • 2020
  • Foreign factors play an important role in the socio-economic development of each country, in which foreign direct investment (FDI), foreign aid and exports of goods and services are always given top priority in undeveloped countries as well as developing countries. The purpose of this study is to examine the relationship between the various factors such as FDI, foreign aid, exports and economic growth in Vietnam. The empirical method employed secondary time-series data set during the period 1997-2018 to determine the impact of FDI, foreign aid and exports on economic growth in Vietnam by using a linear approach. For this study, data is collected from the World Bank and relevant agencies in Vietnam. An empirical model is built with a correlation and regression analysis between economic growth (GDP, current) and three independent variables (FDI, aid, exports of goods and services). The results show that the relationship between FDI (net inflows), aid, exports and GDP (current) has a positive effect at a 1% significance level. Based on these findings, the article recommends that Vietnam continues to seek effective solutions to maintain high economic growth rates by attracting FDI inflows, official development assistance (ODA), and increasing exports of goods and services.

Causal Links from Innovative Activities to Financial Performance in Korean Manufacturing Firms: Mediating Effects of Innovative and Operational Performance (한국 제조업에서 혁신활동과 재무적 성과 간의 인과경로: 혁신성과 및 운영성과의 매개효과를 중심으로)

  • Kim, KonShik
    • Journal of Korea Technology Innovation Society
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    • v.17 no.1
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    • pp.146-173
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    • 2014
  • Extant studies have explained that firm's innovations including technological product and process innovations contribute to its competitive advantage and growth, thereby supporting competitiveness and growth of industry. These studies, however, have focused mainly on the role and effect of technological change that is primarily measured by the patent numbers and R&D intensity. Aside from these traditional streams, there has been growing interest on the impact by various dimensions of innovation including non-technological innovations. Apart from the discussions on the dimensions and scope of innovation, stages or processes of innovation also have been studied. Extant studies on innovation process model, however, has limited its interests in the structure of the transformation of knowledge. This study have established a comprehensive model embracing operational and financial performance to investigate the causal paths between innovation and firm performance. Using multi-level generalized linear model with path analysis, this study have found results as follows: First, the processes from innovative activities to innovation output and outcomes including operational and financial performance at firm level were verified. Secondly, the influence of innovation decreases gradually as the distance away from the direct outputs of the innovation increase in the direction of financial outcomes. Third, the effect of innovation on the sales growth rate is higher for small businesses than for medium-sized businesses. The effect of innovation on the profit rate, however, is significant only for medium-sized businesses. For large businesses, innovation has no positive significant impact on any financial performance at all. Fourth, Fourth, the appropriability of innovation has positive impacts on innovative performance, patent applications, and operational performance.

The Contribution of Innovation on Productivity and Growth in Korea (기술혁신이 생산성과 경제성장에 미치는 영향)

  • Kim, Byung-Woo
    • Journal of Korea Technology Innovation Society
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    • v.11 no.1
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    • pp.72-90
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    • 2008
  • What has been the contribution of industrial innovation to economic growth? Typically, the issue has been approached with growth-accounting methods augmented to include a "stock of knowledge". An independent estimate of the rate of return to R&D is found in order to impute patents granted to the accumulation of knowledge. Griliches(1973) then uses a regression approach to assess the effect of an R&D variable on the computed TFP growth rate. The regression coefficient on the R&D variable would provide an estimate of the social rate of return to R&D. The related studies tend to show high social rates of return to R&D, typically in a range of 20 to 40 % per year. We need to provide multiple equation dynamic system for productivity and innovation in Korean economy in state space form. A wide range of time series models, including the classical linear regression model, can be written and estimated as special cases of a state space specification. State space models have been applied in the econometrics literature to model unobserved variables like productivity. Estimation produces the following results. Considering the goodness of fit, we can see that the evidence is strongly in favor of the range $0.120{\sim}0.135$ for the elasticity of TFP to R&D stock in the period between 1970's and the early 2000's.

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