• 동의생리병리학회지
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• 제20권6호
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• pp.1548-1555
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• 2006

Bujeonghangam-tang(BHT) has been used as an anticancer agent in oriental medicine, but the mechanism by which it induces cell death in cancer cells is still unclear. To investigate cell death mechanism by BHT in cancer cells, the activities of apoptosis signaling pathway were tested in human neuroblastoma cell line LAN5. Viability of LAN5 cells was markedly decreased by treatment of the water extract of BHT in a dose-dependent manner. BHT induced cell death was confirmed as apoptosis characterized by chromatin condensation. We tested whether the water extract of BHT affects the anti-apoptotic protein such as Bcl-2 and Bcl-XL, and the pro-apoptotic protein such as Bax. Both Bcl-2 and Bcl-XL were gradually decreased but Bas was increased in a time-dependent manner after the addition of the water extract of BHT. Cleavage of Bid by activation of caspase-8 protease was also observed in LAN-5 cells by the treatment of the water extract of BHT. Taken together, these results suggest that the water extract of BHT exerts anti-cancer effects on human neuroblastoma LAN-5 cells by inducing the apoptotic death via down-regulation of anti-apoptotic proteins such as Bcl-2 and Bcl-XL, up-regulation of pro-apoptotic protein such as Bax, and activation of intrinsic caspase cascades.

• 제어로봇시스템학회논문지
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• 제13권10호
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• pp.990-999
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• 2007

We deal with second order NMP(Non-Minimum Phase) systems which are difficult to control with conventional methods because of their inherent characteristics of undershoot. In such systems, reducing the undesirable undershoot phenomenon makes the response time of the systems much longer. Moreover, it is impossible to control the magnitude of undershoot in a direct way and to predict the response time. In this paper, we propose a novel two sliding mode control scheme which is capable of determining the magnitude of undershoot and thus the response time of NMP systems a priori. To do this, we introduce two sliding lines which are in charge of control in turn. One is used to stabilize the system and achieve asymptotic regulation eventually like the conventional sliding mode methods and the other to stably control the magnitude of undershoot from the beginning of control until the state meets the first sliding line. This control scheme will be proved to have an asymptotic regulation property. The computer simulation shows that the proposed control scheme is very effective and suitable for controlling the second order NMP system because it can decide the magnitude of undershoot in a direct and stable way and reduce the response time compared with the conventional ones.

• 전력전자학회논문지
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• 제4권1호
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• pp.91-98
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• 1999

본 논문에서는 역률개선용 단일 스위치 부스트 플라이백 결합형 ZCS quasi-resonant converter(QRC)를 제안한다. 제안된 컨버터는 입력전류를 불연속 모드로 동작시켜 역률을 개선하며 입력전류의 zero-crossing-point에서의 왜곡을 개선함으로써 고조파를 감소시켜 역률을 향상시켰으며 좋은 출력전압의 regulation 성능을 가지고 있다. 그리고 체계적인 설계를 위하여 설계식을 제안하였으며 제안된 설계식을 통하여 프로토타입 컨버터를 설계하였다. 실험결과 효율은 약 86%, 역률은 약 0.985이상을 얻었다. 따라서 본 컨버터는 스위칭 주파수가 수백 kHz이상이고 높은 regulation성능을 요구하는 낮은 전압의 소용량 컨버터에 적합하다.

• Journal of Electrical Engineering and Technology
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• 제11권2호
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• pp.300-308
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• 2016

Application of demand-side resources to automatic generation control (AGC) has a great significance for improving the dynamic control performance of power system frequency regulation. This paper investigates the possibility of providing regulation services by demand-side energy storage in electric vehicle battery swapping stations (BSS). An interaction framework, namely station-to-grid (S2G), is presented to integrate BSS energy storage into power grid for giving benefits to frequency regulation. The BSS can be regarded as a lumped battery energy storage station through S2G framework. A supplementary AGC method using demand-side BSS energy storage is developed considering the vehicle user demand of battery swapping. The effects to the AGC performance are evaluated through simulations by using a two-area interconnected power grid model with step and random load disturbance. The results show that the demand-side BSS can significantly suppress the frequency deviation and tie-line power fluctuations.

• 한국자동차공학회논문집
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• 제16권6호
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• pp.157-167
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• 2008

Through this study, the standard design guidelines for high speed train with power cars have been derived to meet the crashworthiness requirements of the Korean rollingstock safety regulation. The crashworthiness regulation requires some performance requirements for two heavy collision accident scenarios; a train-to-train collision at the relative speed of 36 kph, and a collision against a standard deformable obstacle of 15 ton at 110 kph. A standard high speed train composition was defined as 2PC-2ET-6T with 17ton axle load, similar to KTX-2 for the Honam express line. Using theoretical and numerical analyses, some crashworthy design guidelines were derived in terms of mean crush forces and energy absorptions for major crushable components. The derived design guidelines were evaluated and improved using one dimensional spring-mass dynamic simulation. It is shown from the simulation results that the suggested design guidelines can easily satisfy the domestic crashworthiness requirements.

• 환경영향평가
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• 제21권2호
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• pp.289-296
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• 2012

The shock vibration such as machine vibration, blasting vibration etc. has effect on nearby structure as well as human body. The purpose of this study is to predict allowable limit distance of vibration about human body. First of all, vibration velocity such as PPV, PVS was measured by shock vibration experiment, and vibration level was calculated by conversion formula of vibration velocity. And then, allowable limit distance was analyzed by converted vibration level. The results are as follows : Firstly, the correlation coefficient of converted vibration level was over R=0.94, and vibration level caused by PVS was usually represented to high curve line. Secondly, the cross point of vibration level between ground and concrete condition was represented to 66.68dB(V), and allowable limit distance was represented to difference over three times when vibration regulation was raised from 65dB(V) to 80dB(V).

• 한국CDE학회논문집
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• 제19권3호
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• pp.224-235
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• 2014

Recently, Productivity of the construction industry has been decreasing than other industries. Because of this, BIM is being spread in the construction industry. However, quality criteria for BIM data is insufficient. Regulation information is an important factor for initial architectural design evaluations. However, building code and related regulation are numerous. National building code structure in Korea is much more complex than other countries. The purpose of this study is to suggest the typology method of building code and apply to real regulations. To achieve this purpose, the authors have extracted required information to from original regulation for code checking and suggested mapping methods between extracted information and information of IFC scheme. In addition, the authors have represented EXPRESS-G diagram for extracting information from IFC scheme and suggested code checking method through stair case. Output of this study can be used as a base line data for automated code checking system based on open BIM. Automated code checking system will be utilized in architectural design evaluations and supported to increase design quality. It can be used to mount in SEUMTER that is the construction administration system of Ministry of Land, Infrastructure and Transport (MOLIT).

• Journal of Power Electronics
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• 제19권5호
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• pp.1203-1215
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• 2019

Sensorless brushless DC (BLDC) motor drive systems are often subjected to inaccurate commutation signals and can produce high current peaks and conduction consumption. To achieve accurate commutation, a fast commutation shift regulation method for sensorless BLDC motor drive systems considering the influence of the inductance freewheeling process is presented to compensate inaccurate commutation signals. The regulation method is effective in both steady speed and variable speed operations. In the proposed method, the commutation error is gained from the line-voltage difference integral in a 60 electrical-degree conduction period and the outgoing phase current before commutation. In addition, the detection precision of the commutation error is improved due to the consideration of the freewheeling period. The commutation error is directly obtained, which avoids successive optimization and accelerates the convergence rate of the proposed method. Moreover, the commutation error features a positive or negative sign, which can be utilized as an indicator of advanced or delayed commutation. Finally, experiments are conducted to validate the effectiveness and feasibility of the proposed method. The results obtained show that the proposed method can accurately regulate commutation signals.

• 항공우주정책ㆍ법학회지
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• 제30권2호
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• pp.249-277
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• 2015

유럽연합이 제정하여 시행하고 있는 Regulation (EC) No 261/2004 ("Regulation")는 비자발적 탑승거부, 운항취소, 운항지연 등의 사안에 대해 항공승객을 보호하는데 주목적을 두고 있다. 이와 관련하여 항공편 지연으로 불편을 겪은 승객들이 탑승거부, 운항취소에 대해 명시적으로 적용되는 제7조에 따른 금전 보상청구권을 청구한 사건들이 있었다. 이에 대해 유럽연합 사법법원(Court of Justice of the European Union, CJEU)은 승객들에게 시간적인 손실이 발생한다는 점에서 항공편이 운항취소된 경우와 운항지연된 경우는 동일하므로, 당초 항공사가 설정한 총 비행시간 보다 3시간이 초과되어 운항이 지연된 경우에는 해당 승객이 자발적 탑승거부나 운항취소와 마찬가지로 금전손실 보상청구권을 행사할 수 있다고 판단하였다. Regulation상에 운항지연의 경우 제7조의 보상청구권이 적용된다는 명시규정이 존재하지 않음에도 불구하고, 승객의 보호라는 Regulation의 입법취지를 고려하여 법원이 적극적으로 그러한 권리를 긍정한 것이다. 이러한 법원의 관점은 규정의 유추해석이라는 비판을 받을 가능성도 있지만, Regulation에 산재되어 있는 운항취소와 운항지연에 관한 일괄적 취급에 관한 근거 및 승객보호라는 Regulation의 입법취지를 고려할 때 설득력을 가진다. 더욱이 법원은 운항지연의 경우 Regulation과 몬트리올 협약이 동일한 내용을 규정하고 있지 않으므로 몬트리올 협약 제29조는 이 경우에 적용되지 않고 양자는 충돌되지 않는다고 보고 있다. 즉, Regulation은 항공편의 지연이라는 사실에 관한 승객의 불편과 손실을 보호하는 규범인 반면, 몬트리올 협약은 지연이라는 사실로 인하여 인과관계가 인정되는 범위에서 발생된 손해에 관한 배상을 규정하고 있다는 것이다. 위와 같은 유럽연합의 규정과 법원의 견해는 승객보호에 관한 진보적인 성향을 잘 보여주는 선구적인 내용이라고 할 수 있다. 구체적인 규정 없이 승객보호를 위한 절차와 계획의 수립의무만을 선언적으로 규정하고 있는 현재의 우리나라 항공법이 참고할 필요가 있을 것으로 본다.

• 한국실내디자인학회논문집
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• 제16호
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• pp.59-67
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• 1998

This study classifies distinctive peculiarities of cruise interior design which is different from that of structures on the land through the theoretical study on the cruise equipped with functions of hotel and ship. The distinguishing marks are : The first one of the main peculiarities is associated with the International agreement and the safety of passangers and the ship required by the specific regulation. The cruise interior design should be also selectively chosen. The third in comply with the peculiarity of the space plan the base of planning the cruise spaces are as follows : The course of bow and stern the pillar the center line of ship main vertical bulkhead watertight subdivision bulkhead and the deck. The last by special peculiarity of construction materials, materials and products applied for the cruise should meet the regulation of SOLAS and IMCO.