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On-line Image Guided Radiation Therapy using Cone-Beam CT (CBCT) (콘빔CT (CBCT)를 이용한 온라인 영상유도방사선치료 (On-line Image Guided Radiation Therapy))

  • Bak, Jin-O;Jeong, Kyoung-Keun;Keum, Ki-Chang;Park, Suk-Won
    • Radiation Oncology Journal
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    • v.24 no.4
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    • pp.294-299
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    • 2006
  • $\underline{Purpose}$: Using cone beam CT, we can compare the position of the patients at the simulation and the treatment. In on-line image guided radiation therapy, one can utilize this compared data and correct the patient position before treatments. Using cone beam CT, we investigated the errors induced by setting up the patients when use only the markings on the patients' skin. $\underline{Materials\;and\;Methods}$: We obtained the data of three patients that received radiation therapy at the Department of Radiation Oncology in Chung-Ang University during August 2006 and October 2006. Just as normal radiation therapy, patients were aligned on the treatment couch after the simulation and treatment planning. Patients were aligned with lasers according to the marking on the skin that were marked at the simulation time and then cone beam CTs were obtained. Cone beam CTs were fused and compared with simulation CTs and the displacement vectors were calculated. Treatment couches were adjusted according to the displacement vector before treatments. After the treatment, positions were verified with kV X-ray (OBI system). $\underline{Results}$: In the case of head and neck patients, the average sizes of the setup error vectors, given by the cone beam CT, were 0.19 cm for the patient A and 0.18 cm for the patient B. The standard deviations were 0.15 cm and 0.21 cm, each. On the other hand, in the case of the pelvis patient, the average and the standard deviation were 0.37 cm and 0.1 cm. $\underline{Conclusion}$: Through the on-line IGRT using cone beam CT, we could correct the setup errors that could occur in the conventional radiotherapy. The importance of the on-line IGRT should be emphasized in the case of 3D conformal therapy and intensity-modulated radiotherapy, which have complex target shapes and steep dose gradients.

Connecting the Inner and Outer Product of Vectors Based on the History of Mathematics (수학사에 기초한 벡터의 내적과 외적의 연결)

  • Oh, Taek-Keun
    • Journal of Educational Research in Mathematics
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    • v.25 no.2
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    • pp.177-188
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    • 2015
  • In this paper, I investigated the historical development process for the product of two vectors in the plane and space, and draw implications for educational guidance to internal and external product of vectors based on it. The results of the historical analysis show that efforts to define the product of the two line segments having different direction in the plane justified the rules of complex algebraic calculations with its length of the product of their lengths and its direction of the sum of their directions. Also, the efforts to define the product of the two line segments having different direction in three dimensional space led to the introduction of quaternion. In addition, It is founded that the inner product and outer product of vectors was derived from the real part and vector part of multiplication of two quaternions. Based on these results, I claimed that we should review the current deployment method of making inner product and outer product as multiplications that are not related to each other, and suggested one approach for connecting the inner and outer product.

A NEW TYPE 1 AGN POPULATION AND ITS IMPLICATION ON THE AGN UNIFIED MODEL

  • Yi, Sukyoung K.;Oh, Kyuseok;Schawinski, Kevin;Koss, Michael;Trakhtenbrot, Benny
    • The Bulletin of The Korean Astronomical Society
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    • v.40 no.1
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    • pp.43.1-43.1
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    • 2015
  • We have discovered an unexplored population of galaxies featuring weak broad-line regions (BLRs) at z < 0.2 from detailed analysis of galaxy spectra in the Sloan Digital Sky Survey Data Release 7. These objects predominantly show a stellar continuum but also a broad $H{\alpha}$ emission line, indicating the presence of a low-luminosity active galactic nucleus (AGN) oriented so that we are viewing the central engine directly without significant obscuration. These accreting black holes have previously eluded detection due to their weak nature. The new BLR AGNs we found increased the number of known type 1 AGNs by 49%. Some of these new BLR AGNs were detected at the Chandra X-ray Observatory, and their X-ray properties confirm that they are indeed type 1 AGN. Based on our new and more complete catalogue of type 1 AGNs, we derived the type 1 fraction of AGNs as a function of [OIII] ${\lambda}5007$ emission luminosity and explored the possible dilution effect on the obscured AGN due to star-formation. The new type 1 AGN fraction shows much more complex behavior with respect to black hole mass and bolometric luminosity than suggested by the existing receding torus model. The type 1 AGN fraction is sensitive to both of these factors, and there seems to be a sweet spot (ridge) in the diagram of black hole mass and bolometric luminosity. Furthermore, we present a hint that the Eddington ratio plays a role in determining the opening angles. This work is submitted to ApJS.

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A Design of Adaptive Impedance Tuning Circuit for UHF-Band Using λ/4 Transmission Line and π-Network (λ/4 전송 선로와 π-네트워크를 이용한 UHF-대역 적응형 임피던스 정합 회로 설계)

  • Hwang, Soo-Sul;Hong, Sung-Yong
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.23 no.3
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    • pp.367-376
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    • 2012
  • This paper describes a Adaptive Impedance Tuning Circuit which can be adaptively tuned between circuit's characteristic impedance and the arbitrary load impedance. The Adaptive Impedance Tuning Circuit is consisted of such parts as mismatch sensor, impedance tuner and tuning algorithm. Each parts's design methods proposed in other papers are compared with their advantages and disadvantages. And we propose simple design method for Adaptive Impedance Tuning Circuit using a ${\lambda}/4$ transmission line and ${\pi}$-network. Calculation formulas and selection algorithm from calculated values of a complex load impedance are proposed and simulation using induced calculation formulas and selection algorithm is performed. Simulation results show good agreement with theoretical predictions.

Synthesis, Characterization and Biological Activities of 4-(p-Chlorophenyl)-1-(pyridin-2-yl)thiosemicarbazide and Its Metal Complexes

  • Hassanien, Mohammad M.;Mortada, Wael I.;Hassan, Ali M.;El-Asmy, Ahmed A.
    • Journal of the Korean Chemical Society
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    • v.56 no.6
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    • pp.679-691
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    • 2012
  • New series of metal complexes of Co(II), Ni(II), Cu(II), Zn(II), Pd(II) and Pt(II) with 4-(p-chlorophenyl)-1-(pyridin-2-yl)thiosemicarbazide (HCPTS) have been synthesized and characterized by elemental analyses, magnetic moment, spectra (IR, UV-Vis, $^1H$ NMR, mass and ESR) and thermal studies. The IR data suggest different coordination modes for HCPTS which behaves as a monobasic bidentate with all metal ions except Cu(II) and Zn(II) which acts as a monobasic tridentate. Based on the electronic and magnetic studies, Co(II), Cu(II), Pd(II) and Pt(II) complexes have square - planner, Ni(II) has mixed stereochemistry (tetrahedral + square planar), while Zn(II) is tetrahedral. Molar conductance in DMF solution indicates the non-ionic nature of the complexes. The ESR spectra of solid copper(II) complex show $g_{\parallel}$ (2.2221) > $g_{\perp}$ (2.0899) > 2.0023 indicating square-planar structure and the presence of the unpaired electron in the $d_x2_{-y}2$ orbital with significant covalent bond character. The thermal stability and degradation kinetics of the ligand and its metal complexes were studied by TGA and DTA and the kinetic parameters were calculated using Coats-Redfern and Horowitz-Metzger methods. The complexes have more antibacterial activity against some bacteria than the free ligand. However, the ligand has high anticancer activities against HCT116 (human colon carcinoma cell line) and HEPG2 (human liver hepatocellular carcinoma cell line) compared with its complexes.

A Study on the Productivity Improvement of the Dicing Blade Production Process (다이싱 블레이드 제조공정의 생산성향상에 관한 연구)

  • Mun, Jung-Su;Park, Soo-Yong;Lee, Dong-Hyung
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.39 no.3
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    • pp.147-155
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    • 2016
  • Industry 4.0's goal is the 'Smart Factory' that integrates and controls production process, procurement, distribution and service based on the fundamental technology such as internet of the things, cyber physical system, sensor, etc. Basic requirement for successful promotion of this Industry 4.0 is the large supply of semiconductor. However, company I who produces dicing blades has difficulty to meet the increasing demand and has hard time to increase revenue because its raw material includes high price diamond, and requires very complex and sensitive process for production. Therefore, this study is focused on understanding the problems and presenting optimal plan to increase productivity of dicing blade manufacturing processes. We carried out a study as follows to accomplish the above purposes. First, previous researches were investigated. Second, the bottlenecks in manufacturing processes were identified using simulation tool (Arena 14.3). Third, we calculate investment amount according to added equipments purchase and perform economic analysis according to cost and sales increase. Finally, we derive optimum plan for productivity improvement and analyze its expected effect. To summarize these results as follows : First, daily average blade production volume can be increased two times from 60 ea. to 120 ea. by performing mixing job in the day before. Second, work flow can be smoother due to reduced waiting time if more machines are added to improve setting process. It was found that average waiting time of 23 minutes can be reduced to around 9 minutes from current process. Third, it was found through simulation that the whole processing line can compose smoother production line by performing mixing process in advance, and add setting and sintering machines. In the course of this study, it was found that adding more machines to reduce waiting time is not the best alternative.

A study on Check Pattern of Nail Art (네일 아트에 나타난 체크 패턴에 관한 연구)

  • Jeong, Seung-Eun;Kim, Jeong-Mee
    • Journal of the Korea Fashion and Costume Design Association
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    • v.17 no.1
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    • pp.53-68
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    • 2015
  • The purpose of this study is to analyze check pattern of nail art from 2011 to 2013. The results of this study are as follows; 1) Check pattern of nail art is total 257 patterns, and there are 84 argyle, 29 tartan, 24 harlequin, 24 over, 23 window-pane, 15 stitcheds, 13 hound tooth, 10 block, 10 madras, 8 gingham, 8 gradation, 7 shepherd, and 2 tattersall check patterns. Through this result, in nail art, the relatively simple patterns such as a vertical pattern, a horizontal pattern, and cross or overlap diagonal line are used more than elaborate and complex check patterns of a fibrous tissue from a weaving process. 2) In check pattern of nail art, N-affiliated color and R-affiliated color are remarkably well-used, because of the effects of argyle, tartan, window-pane, harlequin, stitched, over, and hound tooth check patterns used the most during the past three years. Especially, most tartan, harlequin, over, and hound tooth check patterns use their own special colors such as R-affiliated colors and N-affiliated colors as it is, and argyle, window-pane, stitched, and over check patterns use well by arranging N-affiliated colors and R-affiliated colors. 3) The most used expressive technique is hand painting to express check pattern in nail art, because new products related to UV gel are well launched. These materials can draw fine line that is hard to express by existing polish easily and simply, and not only have set quickly hard, so procedure time is very short, so it is compatible to draw check pattern personally, but also it is well covered, so check pattern is more clearly expressed.

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Effect of Conditioned Medium of Human Endothelial Cell Line(tHUE-2 cell) on In Vitro Development of Mouse 1-cell Embryos In Vitro Fertilized (체내 수정된 Mouse 1-세포배의 체외발생에 미치는 혈관내피세포주(tHUE-2세포) 배양액의 영향)

  • ;;;Y. Mitsui
    • Korean Journal of Animal Reproduction
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    • v.19 no.2
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    • pp.81-88
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    • 1995
  • Culture medium (ASF-301) of tHUE-2 cell, human endothelial cell line, and culture medium of these cells (conditioned medium : CM) which affect embryonic development of in vivo fertilized 1-cell embryos of mouse were examined. Two-cell stage block of mouse embryos was overicomed in ASF-301 and CM without EDTA, which usually added in basic medium (modified Whitten Medium: MWM, control) to overcome the 2-cell stage block. The developmental rates of embryos to the blastocyst stage were significantly increased in MWM containing 12.5% of growth factors added to ASF-301 (10mg/ $\ell$ transferrin, 1mg/$\ell$ insulin, 0.01mg/$\ell$ EGF) than those of 100% addition and control, 78.0% vs 20.8 and 52.3%, respectively (P<0.05), but the growth factors was not affected the hatching rate of blastocyst. Using ASF-301 or CM which was not treated, embryonic development into the blastocyst and hatched blastocyst stages were not affected. However, proportions of embryonic development into the blastocyst and hatched blastocyst stages were significantly higher in dilution (ASF-301 1:10; CM 1:3~1:6) than those in control (P,0.05). In ASF-301 dialyzed M.W.<10000 dialysis membrane, the developmental rate upto the hatched blastocyst stage was significantly increased, compared to ASF-301 which was not dialyzed (P<0.05), and hatching rate of blastocyst of these group was singnificantly increased than those in MWM (P<0.05). Compared to CM which was not dialyzed, however, in dialyzed CM was significantly decreased, compared to untreated CM (P<0.05), especially any hatched blastocyst was not appeared. As a result of these experiments indicated that a kind or porper treatment such as a dilution of complex synthetic cell culture medium and conditioned medium, and that a optimal concentration of growth factors are usuful for embryo cultrue in vitro.

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Revealing the complexity of ionized gas outflows in powerful Type 2 AGN in the local Universe

  • Karouzos, Marios;Woo, Jong-Hak;Bae, Hyun-Jin
    • The Bulletin of The Korean Astronomical Society
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    • v.40 no.2
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    • pp.32.3-33
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    • 2015
  • There exist scaling relations that link the mass of supermassive black holes with both the velocity dispersion and the mass of the central stellar cusp of their host galaxies. This implies that these two components grow in tandem. Feedback from actively accreting supermassive black holes (AGN), in the form of multi-phase gas outflows, has been argued to be the agent of this co-evolution. Here we employ the powerful GMOS integral field spectroscopy unit on the 8.2m Gemini-North telescope to investigate ionized gas outflows of luminous Type 2 AGN in the local Universe (z<0.1). Our sample of 6 galaxies is drawn from the Sloan Digital Sky Survey (SDSS) and was selected based on their [OIII] dust-corrected luminosity (>1042 erg/s) and signatures of outflows in the [OIII] line profile of their spatially integrated SDSS spectra. These are arguably the best candidates to explore AGN feedback in action since they are < 1% of a large local type 2 AGN SDSS sample selected based on their [OIII] kinematics. We combine a careful spectral decomposition of the [OIII] and $H{\alpha}$ line profiles with spatial information on ~0.5kpc scales to understand the outflow kinematics and energetics in these objects. We find clear evidence for strong outflows in [OIII] and occasionally $H{\alpha}$ that are clearly driven by the ionizing radiation of the AGN. We kinematically and spatially decompose outflowing and rotating ionized gas components. We find [OIII] to be a better tracer of AGN outflows, while $H{\alpha}$ appears to be strongly affected by both stellar rotation and outflows induced by ongoing star formation. The observed kinematics and spatial distribution of the ionized gas imply a large opening angle for the outflow. Finally, we find the projected outflow velocity to decrease as a function of distance, while its dispersion shows a more complex structure with a potentially initially increasing trend (out to 0.5-1kpc distances).

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Network Compression by Saying Idle Time of Resources and Spaces for Repetitive Activities (작업공간과 자원의 여유시간 최소화를 통한 반복작업 공정계획기법)

  • Yi Kyoo Jin
    • Korean Journal of Construction Engineering and Management
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    • v.1 no.3 s.3
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    • pp.75-80
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    • 2000
  • In scheduling multi-unit projects, several alternatives can exist in network construction due to repetitiveness of their activities. Project duration is affected not only by the duration of each activity but also by the arrangement of repeating activities in such projects. This paper provides a network compression method that assigns predecessors to each activity to minimize its float time. Different to the previous efforts that utilized line of balance as the base scheduling-model, this research adopts precedence diagram arranged in two coordinates, the space axis and the resource one. This method seeks the most appropriate predecessors for each activity in each direction of the two coordinates for the purpose of minimizing the idle resource and space. This activity arrangement method was applied to a multi-unit apartment-construction project, to prove its capability of network compression. The result shows that the method successfully sought room for saving construction duration by changing the activity arrangement. The network compression method presented in this research can be utilized in multi-unit construction projects such as apartment complex projects.

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