• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 2004년도 Annual Meeting of the Korean Society ofApplied Pharmacology
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• pp.18-34
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• 2004

This paper will review data obtained primarily from our preclinical investigations that show that exposure to stress has a significant impact on drug taking. Stress increases reward associated with psychomotor stimulants, possibly through a process similar to sensitization, and a growing clinical literature indicates that there is also a link between substance abuse and stress in human addicts. One explanation for the high concordance between stress-related disorders and drug addiction is the self-medication hypothesis, which suggests that a dually-diagnosed person often uses the abused substance to cope with tension associated with life stressors or to relieve symptoms of anxiety and depression resulting from a traumatic event. However, another characteristic of drug self-administration is that drug delivery and its subsequent effects on the HPA axis are under the direct control of the individual. This controlled activation of the HPA axis may result in the production of an internal state of arousal or stimulation that is actually sought by the individual (i.e., the sensation-seeking hypothesis). During abstinence, however, exposure to stressors or drug-associated cues can stimulate the HP A axis to remind the individual about the effects of the abused substance, thus producing craving and promoting relapse. Stress reduction, either alone or in combination with pharmacotherapies targeting the HPA axis may prove beneficial in reducing cravings and promoting abstinence in individuals seeking treatment for addiction. Of primary importance is to reduce the impact of cocaine-associated environmental stimuli on the HPA axis so that they no longer function as triggers for relapse.

• 동의신경정신과학회지
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• 제7권1호
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• pp.15-37
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• 1996

This thesis investigates 220 female students ranging from 19 to 26 years old attending universities in the Wonju area to determine the correlations between mental health and the density of serum iron . According to their serum iron levels, they were divided into three groups and analyzed with the GARS Scale Assessment and the THI Test Assessment. The results are as follows;1. On the comprehensive GARS Scale tests, for all groups, task, occupation and levels of university-related frustration(1) marked the highest scores.2. On the comparative assessment of each group's GARS Scale scores, Group A showed higher stress perception in terms of personal relationship(2,3) than any orther groups. 3. On the comprehensive THI test scores coverring all groups, Multiple subjective symptoms(I) marked the highest scores. 4. On the comparative assessment of each group's THI test scores, Group A showed higher Multiple subjective symptoms(I) and Irregularities of life(G) than any orther groups.5. Comparing and analyzing the GARS Scale Assessment and the THI Test, we found that Group A showed high stress perception, which may cause psychosomatic diseases such as 'yu zheng(鬱證;melancholia). With those results, we can see that the contant of serum iron is correlated to stress perception and the condition of mental health. In the future studies using the GARS Scale and the THI Test, it will be necessary to examine more subject groups in terms of multi-aspects and to investigate the standard group in more detail.

• 인간식물환경학회지
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• 제22권3호
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• pp.269-277
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• 2019

This study aims to see what changes flower arrangement programs bring to the stress index of elderly people with chronic diseases and its correlation with cognition. Furthermore, seniors from a day care center and a nursing home were compared for the purpose of identifying the effectiveness of flower arrangement activities as a supplementary remedy designed to relieve the symptoms and improve the quality of life of patients with chronic diseases. In this study, 24 seniors with chronic diseases were divided into two groups: Group A consists of 15 seniors from a day care center and Group B consists of nine seniors from a nursing home. Both groups participated in simple flower arrangement activities in 10 sessions. In each session, red and green cut flowers that were preferred by the elderly were provided to elicit and develop their thoughts and behaviors. The results showed that the overall average stress index was significantly reduced from 58.0±11.6 before the program to 50.6±17.1 after the program (p = .037). This study examined that the program was more effective for Group A (p = .021) than for Group B (p = .678). Results of the correlation analysis showed that there was no correlation between cognitive function and stress index (p = .569), but that the activity was more effective for Group A. This study shows that arranging flowers effectively lowers the stress index of elderly people with chronic diseases. Also, sharing the outcomes of such activities with others or continuously caring for the flowers even after the activity can maximize the effectiveness of the therapy and rehabilitation. Thus, the study concluded that the program needs to be applied continuously, not in the short-term, in order to relieve or treat the symptoms of elderly patients with chronic diseases.

• 한국멀티미디어학회논문지
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• 제23권1호
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• pp.111-125
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• 2020

In modern society, dementia patients are increasing due to busy daily life. Due to the nature of dementia, family members are having a hard time with their caring activities. Dementia diseases reduce the quality of life not only of the patient, but also of the family, and nursing activities lead to social problems such as unemployment or frequent turnover. This study aims to reduce the difficulty and stress of the nursing process by supporting daily life of dementia patients and nursing activities through smart care platform. Ultimately, we will reduce the cost of treatment for people with dementia and delay the worsening of symptoms through a systematic care program for people with dementia. The smart dementia care platform features smart technology to help the dementia patients' daily lives and support their caregivers.

• Child Health Nursing Research
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• 제26권4호
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• pp.402-410
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• 2020

Purpose: This study aimed to determine the level of health-related quality of life (HRQoL) of children and adolescents who received hematopoietic stem cell transplantation (HSCT) and to examine factors influencing HRQoL. Methods: This cross-sectional descriptive study involved 85 participants aged 10 to 19 years who received treatment from 3 months to 5 years after HSCT. Symptom experiences, stress and coping, self-esteem, social support, and HRQoL were measured. Descriptive analysis, the independent t-test, one-way analysis of variance, Pearson correlation analysis, and stepwise multiple regression were used for data analysis. Results: The mean HRQoL score was 72.26 points out of 100. HRQoL showed statistically significant correlations with symptom experiences, stress, self-esteem, social support, satisfaction with peer relationships, and perceived attentiveness of the medical team. The most influential predictors of HRQoL were symptom experiences (β=-.51, p<.001) and satisfaction with peer relationships (β=.32, p<.001). Conclusion: The experiences of different symptoms by children and adolescents who receive HSCT must be considered. In addition, nursing interventions, such as self-help meetings with peer groups, should be provided to improve their HRQoL.

• 정신신체의학
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• 제23권1호
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• pp.47-56
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• 2015

연구목적 일반대학생과 의과대학생이 경험하는 스트레스 정도와 유형, 삶의 만족도, 삶의 만족도에 영향을 미치는 관련요인 등을 비교해보고자 하였다. 방 법 2013년 11월과 2014년 3월부터 4월까지 광주광역시, 전라남도, 전라북도 소재 4개 대학교의 일반대학생 863명, 의과대학생 851명, 총 1,714명을 대상으로 일반적 정보와 스트레스, 삶의 만족도, 행복도, 음주, 니코틴 의존, 우울증상 등을 포함하는 건강 관련 요인들에 대해 자기보고 질문지를 이용하여 현장 조사하였다. 결 과 첫째, 일반대학생은 의과대학생보다 스트레스 총점이 유의하게 높았다. 일반대학생은 의과대학생에 비해 취업문제에서, 의과대학생은 일반대학생에 비해 학업성취도, 사교 활동의 변화, 친구의 죽음이나 질병에서 유의하게 스트레스를 많이 경험하고 있었다. 둘째, 일반대학생은 의과대학생에 비하여 삶의 만족도가 유의하게 낮았다. 셋째, 삶의 만족도에 영향을 미치는 요인 분석에서 일반대학생은 행복도가, 의과대학생은 우울증상이 가장 설명력이 높은 변인이었다. 결 론 본 연구에서, 일반대학생과 의과대학생이 경험하는 스트레스의 수준과 유형, 삶의 만족도 정도 그리고 삶의 만족도에 미치는 관련요인 등에서 차이가 있음을 확인하였다. 이와 같은 결과는 대학생들에게 스트레스를 해소하고 정신건강과 삶의 만족도를 향상 시킬 수 있는 정신건강 증진 프로그램이 필요함을 시사하고 있다.

• 한국치위생학회지
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• 제16권2호
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• pp.277-284
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• 2016

Objectives: The purpose of the study was to investigate the influencing factors of oral health-related quality of life in social workers. Methods: A self-reported questionnaire was completed by 240 social workers in Gwangju by convenience sampling method. The questionnaire consisted of general characteristics of the subjects(age, monthly salary, smoking, alcohol consumption) and systemic health condition(systemic diseases, medication, oral health status, and stress). The factors associated with oral health-related quality of life included skin dryness, eye dryness, lip dryness, and nasal dryness. The subjective dry mouth consisted of 6 questions measured by visual analogue scale(VAS). Cronbach's alpha was 0.868 in the study. The data were analyzed for t-test, one-way ANOVA and multiple regression analysis using SPSS 18.0 program. Results: The oral health-related quality of life in social workers varied by age, oral health status, stress status, and halitosis. The oral health-related quality of life had positive correlations with the subjective perception of dry mouth and whole body dry symptoms. The health status(${\beta}=-0.410$) had the influence on the oral health-related quality of life, nasal dryness(${\beta}=0.230$), age(${\beta}=0.189$), and halitosis (${\beta}=0.162) in order. Conclusions: The oral health-related quality of life was closely related to the health status and nasal dryness. It is necessary to develop the quality of life improvement programs including oral health prevention and care program in the social workers.

• 정신신체의학
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• 제24권1호
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• pp.66-73
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• 2016

연구목적 소방관에서 기능성 소화불량의 유병률이 높고 기능성 소화불량의 발현과 악화에 심리사회적 요인이 깊이 연관되어 있음에도 불구하고 이에 관한 연구는 매우 부족한 상황이다. 따라서 본 연구에서는 소방관들을 대상으로 기능성 소화불량에 관련되는 심리사회적 요인의 특징을 알아보고 삶의 질에 미치는 영향을 파악하고자 하였다. 방 법 소방관 1,217명을 대상으로 로마 III 진단기준에 따라 기능성 소화불량 집단을 선별하였다. 인구학적 요인을 조사하였으며 심리사회적 요인을 평가하기 위해 Patient Health Questionnaire-9(PHQ-9), Generalized Anxiety Disorder questionnaire-7(GAD-7), Korean Occupational Stress Scale(KOSS), Ways of Coping Checklist(WCCL), Rosenberg's Self-Esteem Scale(RSES) 그리고 World Health Organization Quality of Life Scale abbreviated version(WHOQOL-BREF)를 사용하였다. 기능성 소화불량에 따라 집단을 나누고 교차분석(chisquare test)과 독립표본 t-검정(independent t-test)을 사용하여 집단 간의 차이를 알아보았다. 또한 KOSS의 각 하위 영역별로 기능성 소화불량의 위험도를 평가하기 위해 로지스틱 회귀분석(logistic regres-sion analysis)을 시행하였다. 기능성 소화불량 집단의 삶의 질과 독립변인들의 상관관계를 파악하기 위해 Pearson 상관분석(Pearson's correlation test)을 시행하였으며, 위계적 회귀분석(hierarchical regression anal-ysis)을 통해 기능성 소화불량 집단의 삶의 질에 영향을 미치는 예측 요인을 알아보았다. 결 과 기능성 소화불량 집단은 남성(p=0.006)이 많았고, PHQ-9(p<0.001), GAD-7(p<0.001), KOSS(p<0.001) 점수가 유의미하게 높았으며, RSES(p=0.008), WHOQOL-BREF(p<0.001) 점수는 유의미하게 낮았다. KOSS 하위 영역 중 높은 직무요구도(OR 1.94, 95% CI : 1.29-2.93), 부적절한 보상(OR 2.47, 95% CI : 1.61-3.81), 그리고 불편한 직장 문화(OR 1.51, 95% CI : 1.01-2.24)에서 기능성 소화불량의 위험도가 높았다. 기능성 소화불량 집단의 삶의 질에 대한 최종 회귀모델에서 우울증상과 직무스트레스가 낮고, 자아존중감이 높은 것이 삶의 질의 42.0%를 설명했다. 결 론 본 연구 결과 기능성 소화불량 및 삶의 질에 대한 심리사회적 요인의 영향이 확인되었다. 따라서 향후 기능성 소화불량의 평가에 있어 내과적 접근 뿐만 아니라 정신건강의학과적인 접근이 동시에 이루어져야 할 것으로 판단된다.

• 한방안이비인후피부과학회지
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• 제16권3호
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• pp.185-199
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• 2003

Objectives : The purpose of this clinical report was to estimate the efficacy of Lizhongtang plus Baidusan(理中湯合敗毒散) on allergic rhinitis. Methods : We prescribed Lizhongtang plus Baidusan(理中湯合敗毒散) for 15 patients who visited Kabsan oriental clinic with allergic rhinitis. We inquired into distribution of age, case history period, improvement of symptoms, etc. We used the statistical methods of student t-test in order to analysis of the different of symptom before and after treatment(p 〈0.05). Results : 1. The distribution of sex & age was as follows; Total patient were women. 10-19 years 2 cases, , 30-39 years 5 cases, 40-49 years 6 cases and 50-59 years 2 cases. 2. The case of history period was as follows; under a year 1 case, 1-3 years 3 cases, 3-5 years 2 cases, 5-10 years 4 cases and over 10 years 5 cases. 3. The amount of herbal medicine they took as follows: 1 je(劑) 1 case, 2 je(劑) 7 cases, 3 je(劑) 5 cases and 4 je(劑) 2 cases. 4. The frequency of acupuncture and moxibustion was as follows; under 5 times 1 case, 6-10 times 10 cases, 11-15 times 3 cases, over 16 times 1 case. 5. The nasal symptoms except the nasal mucosa color(pale) were improved significantly after treatment(p 〈0.05). 6 The general symptoms except menstruation pain were improved significantly after treatment(p 〈0.05). 7. The curative influence of rhinitis by Lizhongtang plus Baidusan(理中湯合敗毒散) was as follows excellent 2 cases. good 11 cases, ineffectiveness 2 cases. Conclusion: If we administer Lizhongtang plus Baidusan(理中湯合敗毒散) to allergic rhinitis patients with cold in the Zhong Jiao of deficiency type (中焦虛寒), it improves not only allergic symptoms such as the watery rhinorrhea, turbinate swelling, sneeze, nasal obstruction, etc but also coldness of the limbs(手足冷症), dyspepsia, dysmenorrhea, etc. Therefore, we consider that administration of Lizhongtang plus Baidusan(理中湯合敗毒散) to allergic rhinitis patients with cold in the Zhong Jiao of deficiency type (中焦虛寒) improves in quality of life, as removes inconvenience of life and stress.

• 디지털융복합연구
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• 제17권12호
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• pp.413-425
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• 2019

본 연구는 저학년 간호대학생의 우울 영향 요인을 탐색하기 위한 서술적 조사연구이다. 본 연구를 위해 S와 G지역의 종합대학 저학년 간호대학생 144명에게 신체증상, 수면의 질, 스트레스, 대학생활 적응, 우울로 구성된 자가보고식 설문지로 자료를 수집하였다. 저학년 간호대학생의 우울은 평균 18.89점이며, 58.3%가 임상치료가 필요한 우울증상을 경험하고 있었다. 우울 영향 요인으로 대학생활 적응(β=-.503, p=.000), 신체증상(β=.263, p=.000)순으로 나타났고, 우울의 설명력은 58.9%로 나타났다. 이에 저학년 간호대학생의 우울을 조절하기 위해서 입학초기부터 기초학습 능력을 진단하고, 학습능력향상을 위한 수준별 맞춤형 프로그램 제공을 통해 학문적 적응을 돕는 지도관리 방안이 마련되어야 할 것이다. 또한 다빈도로 경험하는 피로감/기운없음과 같은 신체증상을 완화하기 위한 다양한 중재프로그램의 개발 및 적용이 필요하다.