• 한국초등수학교육학회지
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• 제14권3호
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• pp.745-768
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• 2010

본 연구는 수준이 다른 여러 영재 집단의 소속 학생들이 도형수와 관련된 과제를 해결하고 창의적 산출물을 도출하는 가운데 그들의 수학적 사고력과 창의적인 아이디어를 발휘할 수 있도록 수준별 수학 영재 교수 학습 자료를 개발하는 절차와 방법을 탐구해 보는 데 그 목적이 있다. 이를 위해 교수 학습 자료 개발의 준거와 절차 모형에 따라 도형수 과제의 교수 학습 자료의 원형과 실제적인 자료를 개발하고 그것을 현장 수업에 적용하면서 학생들의 다양한 해결과정을 분석하면서 그 자료의 문제점과 개선점을 제시하였다. 그리고 초등학교에서 집단의 수준별로 산출물 탐구가 가능한 도형수의 내용 범위를 설정해 보면서 차후 유사한 다른 수학 영재 교수 학습 자료 개발할 때 고려한 네 가지의 시사점을 제안하였다.

• Asian-Australasian Journal of Animal Sciences
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• 제15권10호
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• pp.1403-1411
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• 2002

The aims of this study were, firstly, to analyze the biochemical compositions of serum and follicular fluid (FF) from prepubertal gilts after PMSG (1,000 IU) treatment. The concentrations of total proteins, lipids, cholesterol, glucose and sex hormones (progesterone, $P_4$; estradiol-$17{\beta}$, $E_2$; testosterone, T) were measured. Secondary, the effects of porcine FF (pFF) addition (40% and 100%) in IVM media and different culture conditions [Exp. 1: mBMOC-2+20% porcine serum (PS), fresh IVM medium, filtered IVMconditioned medium, or rabbit oviducts; Exp. 2: mBMOC-2+20%PS or stepwise medium replacement procedures (SMRP) cocultured with or without cumulus cells] on the in vitro development (IVD) of porcine oocytes were also examined. Results showed that no significant differences were found in total protein levels between serum and pFF from different sizes (large, >7 mm; medium, ~5-7 mm; small, <3-5 mm) of follicles (75-85 and 49-90 mg/dl; p>0.05). Total lipid concentrations remained constant in serum (395-472 mg/dl), and reduced significantly in the pFF from large follicles (287 mg/dl) at 132 h after PMSG treatment when compared to those at other time points (441-480 mg/dl). Basal cholesterol levels in serum and pFF at 12 h were similar (153-161 mg/dl), but increased at 36 h (186-197 mg/dl). Basal P4 and E2 levels in serum (0.1 ng/ml and 5.5 pg/ml) were low, but increased from 0.34 ng/ml and 12.13 pg/ml at 24 h to 0.81 ng/ml and 61.70 pg/ml at 98 h, respectively, after PMSG treatment (p<0.05). P4 levels increased linearly in pFF from large follicles during 12 through 132 h (138-1,288 ng/ml). A similar increase was also observed in $E_2$ levels (22-730 pg/ml) before 60 h post PMSG treatment, and then dropped afterwards (730-121 pg/ml). The development of the oocytes fertilized in 40% pFF-medium was greater than that in 100% pFF-medium group without gonaodtropin addition (31% vs 10%, p<0.05). However, both were lower than those in mBMOC-2+20%PS and in rabbit oviducts (p<0.05). When cocultured with cumulus cell monolayers, a greater cleavage rate was observed in the group cultured in filtered IVM-conditioned medium than the SMRP group (36% vs 18%, p<0.05). A similar phenomenon was also observed in the culture without cumulus cell monolayers (33% vs 19%, p<0.05). It is concluded that neither the fresh IVM nor filtered IVM-conditioned medium has positive effect on the IVD of oocytes. Coculture with cumulus cell monolayers and the SMRP were not beneficial to the development of IVF pig oocytes.

• 농촌지도와개발
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• 제21권1호
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• pp.83-115
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• 2014

본 연구는 대형유통업체의 PB사과 상품에 대한 소비자들의 지각수준에서 브랜드신뢰와 구매의도에 영향을 미치는 요인을 밝혀서 대형유통업체의 PB사과 상품 확대에 대응하는 농업 경영체 및 산지 생산농가의 마케팅 전략의 시사점을 제시 하고자 하였다. 분석결과, PB사과 상품의 품질수준은 브랜드신뢰에 영향을 미치고, 품질수준과 지각가치, 브랜드신뢰가 구매의도에 영향을 주었다. 그러나 브랜드이미지는 브랜드신뢰와 구매의도에 영향을 미치지 않았다. 이에 따른 전략적 시사점은 첫째, NB 사과의 전통성을 강조하여 품질수준에 대한 인식형성이 이루어질 수 있도록 해야 한다. 둘째, 소비자들의 구매의욕을 일으킬 수 있는 감성적 포장디자인과 다양한 구성의 상품개발이 필요하다. 셋째, NB사과에 대한 소비자들의 지각가치 향상을 위해서 NB사과 상품구매의 편리성제공으로 지각가치를 향상 시켜야 한다. 넷째, 생산자 단체와 소비자단체의 지속적인 연계활동을 통하여 NB사과 상품에 대한 브랜드 신뢰도를 향상 시켜야 한다.

• 생약학회지
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• 제47권2호
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• pp.158-164
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• 2016

This study was conducted to verify the potential of Allium hookeri to control blood glucose metabolism in diabetes model. We fed the experimental diets(ALE, ARE) supplemented with the extract of Allium hookeri leaf or root at 1% of diet to the diabetic mice (C57BLKS/J, db/db) for 8 weeks. Hetero and control mice were fed the control diet without any extract of Allium hookeri leaf or root. At 8th week of feeding the diets, we measured body weight, blood glucose, HbA1c, and plasma insulin levels and conducted an oral glucose tolerance test (OGTT) and staining insulin immunoreactive cells in islets of pancreas. ARE group treated with the root of A. hookeri showed significantly lower blood glucose levels than the Cont group at 120 min in the OGTT. However, HbA1c level was significantly reduced in both ALE and ARE groups, and higher serum insulin levels and increased density of insulin immunoreactive cells compared with the Cont group were found in these 2 groups. Based on these results, A. hookeri is considered to be effective in improving glucose tolerance by partially affecting insulin secretion and it may be used to prevent and treat diabetic disease.

• 한국식품위생안전성학회지
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• 제35권1호
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• pp.13-22
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• 2020

잡곡의 Fusarium 곰팡이독소의 오염 조사를 위해, 총 244개 잡곡시료(귀리, 수수, 율무, 기장)를 수확기 포장에서 2017년과 2018년에 수집하였다. 데옥시니발레놀(DON), 니발레놀(NIV), 제랄레논(ZEA)은 면역친화컬럼법과 UPLC를 이용하여 분석하였으며, 푸모니신(FUM)은 QuEChERS 방법과 LC-MS를 이용하여 분석하였다. 잡곡 시료 중 귀리의 NIV 오염수준은 120.0-3277.0 mg/kg로 다른 잡곡에 비해 가장 높았다. 율무에서는 DON이 최대 730.0 ㎍/kg 검출되었다. 기장의 NIV과 ZEA의 오염빈도는 각각 61.5%와 57.9%로 높았으나 평균 오염량은 각각 75.6 ㎍/kg과 21.5 ㎍/kg로 안전한 수준이었다. 잡곡 시료 중 수수는 DON, ZEA, FUM의 오염빈도가 가장 높았으며, 2 종 이상의 Fusarium 독소 중복 오염률이 70.0%로 잡곡 평균 29.9%에 비해 높았다. 잡곡 재배포장에서 Fusarium 독소오염을 안전하게 관리하기 위하여 독소 발생 모니터링과 함께 오염예방기술 개발 연구가 수행되어야 할 필요가 있다.

• 한국가금학회지
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• 제40권4호
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• pp.337-349
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• 2013

본 총설은 논란이 되고 있는 계란 콜레스테롤이 심장질환과 관련성이 없다는 것을 증명하기 위하여 지난 50여 년간의 연구 결과를 조사하였다. 그 결과, 식이로 섭취된 콜레스테롤은 혈액 콜레스테롤 농도에 큰 영향을 미치지 않는 것이 밝혀졌다. 더욱이 고콜레스테롤혈증이 있는 중년 남녀에게 1일 2개의 계란을 더 섭취한 실험에서도 혈액 콜레스테롤이 증가되지 않는 것으로 나타났다. 식이 콜레스테롤 섭취가 증가하면 LDL-콜레스테롤 뿐 아니라, HDL-콜레스테롤도 같이 증가하여 심장질환 위험의 중요 지표인 LDL : HDL 비율은 거의 변화가 없었다. 특히 노인에게서 더 좋은 지표로 밝혀진 HDL-콜레스테롤이 증가하므로, 콜레스테롤 섭취는 심장질환 예방에 좋은 것으로 나타났다. 따라서 계란의 섭취는 건강에 나쁘다고 알려진 인식은 사실이 아니며, 오히려 심장질환 예방에 효과적인 것으로 밝혀졌다. 또한, 계란 섭취량에 관한 공식적인 기준도 없는 것으로 나타났다. 따라서 이와 같은 증거들은 더 이상 계란에 대한 오해와 불신이 없기를 제안한다.

• The Plant Pathology Journal
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• 제17권6호
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• pp.342-346
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• 2001

The physiological changes in sorghum (Sorghum vulgare Pers.) leaves infected with Drechslera sorghicola were investigated through five recognizable stages of disease development. Water-soaked yellowish brown spots developed two days after inoculation, turned brown with yellow halo, enlarged and coalesced at later stages of disease development. Healthy and infected leaves were analyzed for different biochemical constituents. The chlorophyll contents were decreased significantly with the progress of infection. The levels of reducing and total sugars increased while non-reducing sugars decreased to a significant extent with the progress of disease. The concentration of total phenolics, orthodihydroxy phenols, free and glycosidic phenols showed significant changes due to infection, whereas basic and acid phenols showed little or no change with disease development. Levels of phenolic compounds increased four days after inoculation and decrease thereafter, but the concentration was higher at every stage of disease development relative to healthy tissues. Polyphenol oxidase and peroxidase enzyme activities increased to varying degrees at different stages of infection. Analysis of protein fractions showed a significant increase with the progress of disease.

• Asian-Australasian Journal of Animal Sciences
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• 제7권2호
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• pp.289-294
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• 1994

This report deals with the effect of levels of concentrate supplementary feeding (Nil, 0.25% BW and 0.75% BW) on the productivity of different genotypes (Thai native (TN), 25% Anglo-Nubian (AN), 50% AN and 75% AN) of female goats grazing newly established pasture in a tropical area. The major species of grass was Brachiaria mutica (33%) and of legumes was Centrosema pubescens (34%). There was no significant (p>0.05) difference between nil and 0.25% BW supplementary feeding for growth rate ($g/kg^{0.75}/d$). However, goats fed 0.75% BW supplementary feeding had significantly (p<0.01) higher growth rates than did other treatments. There was no significant (p>0.05) difference among genotypes and between age for growth rate. There was no interaction between feeding and genotype for growth rate.

• The Journal of Asian Finance, Economics and Business
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• 제6권2호
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• pp.299-307
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• 2019

This study aims to explore the theoretical concepts of inclusive development in relation to the spatial context, assessment the disparities in the social and economic development of the regions of Kazakhstan and substantiate the main mechanisms for overcoming them. In this research, authors propose the methodological tools for presenting a standard form of evaluation of social and economic development in the regions of Kazakhstan. In this study used methods, which based on measuring disproportions between the levels of economic and social development of the regions, as well as disproportions between the republican and regional levels. According to the author's methodological approach, complex and integral indexes have calculated over the period 2012-2017 for a number of indicators adapted to the conditions of Kazakhstan. The calculated indexes proposed to use as instruments for measuring the level of the social and economic development. In addition, according the obtained indexes and the results of their ranking can be the basis for the development of regional programs and management decisions. This will improve the targeted support of the population in backward regions in order to ensure inclusive development and improve the quality of life of the population.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 1995년도 춘계학술대회
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• pp.64-64
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• 1995

Cholesteryl Ester Transfer Protein (CETP) mediates the transfer of cholesterol ester and triglyceride between high-density lipoprotein (HDL) and other low-density lipoproteins, therefore, it might influence HDL levels. The levels of HDL is closely related to the atherogenic diseases in human and there were several reports that the trasgenic mice expressing CETP had much worse atherosclerosis than non-expressing control one. Therefore, selective inhibitors of CETP have the potential to be used as antiatherosclerotic agents. Continued screening for potent inhibitors of CETP led to the isolation of Suberitenone B from marine sponge. Suberitenone B, sesterterpenoids of a new skeletal class have been isolated from the sponge Suberites sp. collected from King George Island the Antartic. The structure of the metabolite has been determined by NMR experiments and chemical methods.