• Journal of Technologic Dentistry
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• v.35 no.3
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• pp.193-200
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• 2013

Purpose: In this study, in order to provide objective standard of the mixed concentration of the zirconia coloring-liquids, compare the shade differences after colored zirconia blocks from different concentrations. Methods: After immersion for 2 minutes zirconia specimen ($1.5{\times}1.5{\times}0.6{\pm}0.01mm$) in coloring-liquids that produced different concentrations, were sintered in furnace dedicated. Then, it was measured in spectrophotometer and Shadepilot. It has been determined mean and standard deviation of the color difference for each group, and verified by one-way ANOVA using the (version12.0) SPSS WIN Program the difference in shade according to the concentration at the significance level of 95% confidence, it conducted a Tukey's multiple range test to post-test. Results: The mean of $L^*$ was decreased toward LN35 group, however the mean of $a^*$ and $b^*$ was increased(p<.05). There is a statistically significant difference in the results of $L^*$ post hoc test of each group was LN15-LN30/LN35, LN20-LN30/LN35, LN25-LN30/LN35, and LN30-LN35 group. The $a^*$ group, it was found that there is a statistically significant difference in all groups for each(p<.05). The $b^*$ group, it was found that there is a statistically significant difference in all groups except the LN25-LN30(p<.05). Conclusion: In order to make effective use of the coloring-liquids of zirconia, the device objective, accurate concentration measurement is required, from the present study, we presented evidence basic to this.

• The Journal of Advanced Prosthodontics
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• v.9 no.4
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• pp.239-243
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• 2017

PURPOSE. The purpose of this study is to compare single and three-unit metal frameworks that are produced by micro-stereolithography. MATERIALS AND METHODS. Silicone impressions of a selected molar and a premolar were used to make master abutments that were scanned into a stereolithography file. The file was processed with computer aided design software to create single and three-unit designs from which resin frameworks were created using micro-stereolithography. These resin frameworks were subjected to investment, burnout, and casting to fabricate single and three-unit metal ones that were measured under a digital microscope by using the silicone replica technique. The measurements were verified by means of the Mann-Whitney U test (${\alpha}=.05$). RESULTS. The marginal gap was $101.9{\pm}53.4{\mu}m$ for SM group and $104.3{\pm}62.9{\mu}m$ for TUM group. The measurement of non-pontics in a single metal framework was $93.6{\pm}43.9{\mu}m$, and that of non-pontics in a three-unit metal framework was $64.9{\pm}46.5{\mu}m$. The dimension of pontics in a single metal framework was $110.2{\pm}61.4{\mu}m$, and that of pontics in a three-unit metal framework was $143.7{\pm}51.8{\mu}m$. CONCLUSION. The marginal gap was smaller for the single metal framework than for the three-unit one, which requires further improvement before it can be used for clinical purposes.

• Journal of Technologic Dentistry
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• v.42 no.1
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• pp.9-16
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• 2020

Purpose: The purpose of this study was to compare the marginal and internal fit of lithium disilicate ceramic inlay produced by heat pressing that inlay pattern made by subtractive manufacturing and additive manufacturing method. Methods: A mandibular lower first molar that mesial occlusal cavity (MO cavity) die was prepared. After fabricating an epoxy resin model using a silicone impression material, epoxy resin die was scanned with a dental model scanner to design an MO cavity inlay. The designed STL pile was used to fabricate wax patterns and resin patterns, and then lithium disilicate ceramic inlays were fabricated using hot-press method. For the measurement of the marginal and internal gap of the lithium disilicate, silicone replica method was applied, and gap was measured through an optical microscope (x 80). Data were tested for significant differences using the Mann-Whitney Utest. Results: The marginal fit was 103.56±9.92㎛ in the MIL-IN group and 81.57±9.33㎛ in the SLA-IN group, with a significant difference found between the two groups (p<0.05). The internal fit was 120.99±17.52㎛ in the MIL-IN group and 99.18±6.65㎛ in the SLA-IN group, with a significant difference found between the two groups (p<0.05). Conclusion: It is clinically more appropriate to apply the additive manufacturing than subtractive manufacturing method in producing lithium disilicate inlay using CAD/CAM system.

• Annals of Laboratory Medicine
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• v.38 no.6
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• pp.530-537
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• 2018

Background: Measurement of insulin and C-peptide concentrations is important for deciding whether insulin treatment is required in diabetic patients. We aimed to investigate the analytical performance of insulin and C-peptide assays using the Lumipulse G1200 system (Fujirebio Inc., Tokyo, Japan). Methods: We examined the precision, linearity, and cross-reactivity of insulin and C-peptide using five insulin analogues and purified proinsulin. A method comparison was conducted between the Lumipulse G1200 and Roche E170 (Roche Diagnostics, Mannheim, Germany) systems in 200 diabetic patients on insulin treatment. Reference intervals for insulin and C-peptide concentrations were determined in 279 healthy individuals. Results: For insulin and C-peptide assays, within-laboratory precision (% CV) was 3.78-4.14 and 2.89-3.35%, respectively. The linearity of the insulin assay in the range of 0-2,778 pmol/L was $R^2=0.9997$, and that of the C-peptide assay in the range of 0-10 nmol/L was $R^2=0.9996$. The correlation coefficient (r) between the Roche E170 and Lumipulse G1200 results was 0.943 (P <0.001) for insulin and 0.996 (P <0.001) for C-peptide. The mean differences in insulin and C-peptide between Lumipulse G1200 and the Roche E170 were 19.4 pmol/L and 0.2 nmol/L, respectively. None of the insulin analogues or proinsulin showed significant cross-reactivity with the Lumipulse G1200. Reference intervals of insulin and C-peptide were 7.64-70.14 pmol/L and 0.17-0.85 nmol/L, respectively. Conclusions: Insulin and C-peptide tests on the Lumipulse G1200 show adequate analytical performance and are expected to be acceptable for use in clinical areas.

• Safety and Health at Work
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• v.2 no.4
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• pp.348-354
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• 2011

Objectives: This cross-sectional study was performed in the Dental School of Prince of Songkla University to ascertain noise exposure of dentists, dental assistants, and laboratory technicians. A noise spectral analysis was taken to illustrate the spectra of dental devices. Methods: A noise evaluation was performed to measure the noise level at dental clinics and one dental laboratory from May to December 2010. Noise spectral data of dental devices were taken during dental practices at the dental services clinic and at the dental laboratory. A noise dosimeter was set following the Occupational Safety and Health Administration criteria and then attached to the subjects' collar to record personal noise dose exposure during working periods. Results: The peaks of the noise spectrum of dental instruments were at 1,000, 4,000, and 8,000 Hz which depended on the type of instrument. The differences in working areas and job positions had an influence on the level of noise exposure (p < 0.01). Noise measurement in the personal hearing zone found that the laboratory technicians were exposed to the highest impulsive noise levels (137.1 dBC). The dentists and dental assistants who worked at a pedodontic clinic had the highest percent noise dose (4.60 ${\pm}$ 3.59%). In the working areas, the 8-hour time-weighted average of noise levels ranged between 49.7-58.1 dBA while the noisiest working area was the dental laboratory. Conclusion: Dental personnel are exposed to noise intensities lower than occupational exposure limits. Therefore, these dental personnel may not experience a noise-induced hearing loss.

• The Korean Journal of Pain
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• v.35 no.2
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• pp.140-151
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• 2022

Background: Essential oils are of great interest for their analgesic and anti-inflammatory properties. We aimed to study the content of the essential oil of the Origanum vulgare of the Armenian highlands (OVA) in different periods of vegetation and to investigate its antinociceptive and anti-inflammatory effects in mice (in vivo) and cytotoxic action in cultured cells (in vitro). OVA essential oil was extracted from fresh plant material by hydro-distillation. Methods: For OVA essential oil contents determination the gas chromatography-mass spectrometry method was used. Formalin and hot plate tests and analysis of cell viability using the methyl-thiazolyl-tetrazolium (MTT) assay were used. Results: The maximal content of β-caryophyllene and β-caryophyllene oxide in OVA essential oil was revealed in the period of blossoming (8.18% and 13.36%, correspondently). In the formalin test, 4% OVA essential oil solution (3.5 mg/mouse) exerts significant antinociceptive and anti-inflammatory effects (P = 0.003). MTT assay shows approximately 60% cytotoxicity in HeLa and Vero cells for 2.0 µL/mL OVA essential oil in media. Conclusions: The wild oregano herb of Armenian highlands, harvested in the blossoming period, may be considered as a valuable source for developing pain-relieving preparations.

• Journal of the Korean Society of Physical Medicine
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• v.19 no.1
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• pp.31-41
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• 2024

PURPOSE: This study examined the distribution dynamics and proposed determinants, including morphological measurements, clinical laboratory tests, and lifestyle factors among young Korean men aged 20 to 29 years with the coexistence of age-related loss of skeletal muscle mass and obesity (CALSMO). METHODS: Six hundred and sixty-six participants were divided into two groups based on their skeletal muscle mass index, with 12 individuals categorized in the CALSMO group and the remaining 654 in the normal group. The proposed determinants variables consisted of three main components: morphological measurements, clinical laboratory tests, and lifestyle factors. The morphological measurement variables were height, weight, body mass index, waist circumference, and skeletal muscle mass index. The clinical laboratory tests were fasting glucose, triglyceride, total cholesterol levels, and systolic and diastolic blood pressure. The lifestyle factors considered were alcohol consumption and tobacco use. Complex sampling analysis was performed for the evaluation. RESULTS: The distribution dynamics were determined to be 1.81(1.02-3.18) %. Morphological factors, such as height, weight, body mass index, waist circumference, and skeletal muscle mass index, showed significant differences (p < .05). The clinical laboratory test variables, specifically the fasting glucose, triglyceride, and total cholesterol levels, also exhibited significant differences (p < .05). The lifestyle factor, alcohol consumption, also showed a significance (p < .05). CONCLUSION: This study provides insights into the distribution dynamics. The proposed determinants in young Korean individuals with CALSMO are height, weight, body mass index, waist circumference, skeletal muscle mass index, fasting glucose, triglyceride, total cholesterol levels, and alcohol consumption.

• Progress in Medical Physics
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• v.30 no.2
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• pp.59-63
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• 2019

Purpose: To manage radiation measurement equipment, a web-based management program has been developed in this study. Materials and Methods: This program is based on a web service and Java Server Pages (JSP) and employs compatibility and accessibility. Results: The first step in the workflow has been designed to create accounts for each user or organization and to log in. The program consists of two parts: fields for listed instruments, and measurement information. The instruments for measuring radiation listed in this program are as follows: ionization chambers, survey meters, thermometers, barometers, electrometers, and phantoms. Instrument properties can be put in the recording fields and browsing for associated instruments can be performed. The main part of the program is the cross-calibration for each ion chamber. For instance, the ionization chamber to be used as a relative dosimeter can be registered by cross-calibration data with a reference chamber calibrated by an accredited laboratory. This program supports methods using the central axis transfer theory for cross-calibration for the ionization chambers. The reference and field ionization chambers were placed in a solid water phantom along the beam central axis at two different depths, and then the positions were switched. Each measured value was used for calculating the cross-calibration factor. Conclusions: Because many instruments are used and managed in radiation oncology departments, systematic, traceable recording is very important. The web-based program developed in this study is expected to be used effectively in the maintenance of radiation measurement instruments.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.23 no.3
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• pp.250-260
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• 2013

Objectives: The aim of this study is to analyze the current status of the possession of measurement and analytical instruments among work environment monitoring organizations that have been designated by the Ministry of Employment and Labor (MoEL) in Korea. Methods: Data for measurement and analytical instruments were gathered by inspectors who had been assigned by the Korea Occupational Safety and Health Agency (KOSHA) and MoEL during the evaluation program for designated work environment monitoring service providers in 2012. Data for 11 monitoring instruments and nine analytical instruments were collected from 108 organizations. Basic data such as the type of service provides and the size of employment were also recorded by the inspector. Results: The total number of personal air samplers including high and low flow rates operated in Korea was 5,418, with average of 50.2. Average operation number of noise dosimeters was 35.0, while 3,780 dosimeters were used in 108 work environment monitoring organizations. There were 10,488 monitoring instruments in total. All service providers possessed at least one AAS and GC in their analytical laboratory. Total number of HPLC/MS was five, followed by ICP/MS of seven, with an average of 0.07. Conclusions: Based on the data, domestic work environment monitoring service providers possessed relatively reasonable measurement and analytical instruments. Nearly all instruments had been imported from advanced countries such as USA, UK and Japan. Periodic gathering of data on these instruments may help maintain good workplace monitoring results and the health of workers at the sites.

• Journal of the Korean Geotechnical Society
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• v.24 no.10
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• pp.25-32
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• 2008

Based on recent studies, the side resistance of rock socketed drilled shafts was affected by unconfined compressive strength of rock, socket roughness, rock types and joints, and initial normal stress. Especially, the socket roughness was affected by rock types and joints, drilling methods, and diameters of pile. In this study, a new roughness measurement system (BKS-LRPS, Backyoung-KyungSung Laser Roughness Profiling System) usable in water was developed. Based on the laboratory model tests, an EMD (Effective Measurement Distances) according to various turbidity was proposed as $EMD=1149.2{\times}T_{b}^{-0.64}$.