• Journal of Photoscience
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• v.8 no.1
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• pp.1-7
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• 2001

The deteriorative effect of ultraviolet-B(UV-B) radiation on photosynthesis was assessed by the simultaneous measurement of O$_2$ evolution and chlorophyll(Chl) fluorescence in green pepper. UV-B was given at the intensity of 1 W$.$m$\^$-2/, a dosage often encountered in urban area of Seoul in Korea, to detached leaves. Both Pmax and quantum yield of O$_2$ evolution was rapidly decreased, in a parallel phase, with increasing time of UV-B treatment. Chl fluorescence parameters were also significantly affected. Fo was increased while both Fm and Fv were decreased. Photochemical efficiency of PSII(Fv/Fm) was also declined, although to a lesser extent than Pmax. Both qP and NPQ were decreased similarly with increasing time of UV-B treatment. However, PS I remained stable. The addition of lincomycin prior to UV-B treatment accelerated the decline in Fv/Fm to some extent, suggesting that D1 protein turnover may play a role in overcoming the harmful effect of UV-B. The amount of photosynthetic pigments was less affected than photosynthetic response in showing decline in Chl a and carotenoids after 24 h-treatment. Presumptive flavonoid contents, measured by changes in absorbance at 270 nm , 300 nm and 330nm, were all increased by roughly 50% after 8 h-treatment. Among antioxidant enzymes, activities of catalase and peroxidase were steadily increased until 12h of UV-B treatment whereas ascorbate perxidase, dehydroascorvate reductase and glutathione reductase did not show any significant change. The results indicate that deteriorative effect of UV-B on photosynthesis precedes the protection exerted by pigment synthesis and antioxidant enzymes.

• The Korean Journal of Food And Nutrition
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• v.19 no.2
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• pp.201-206
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• 2006

Numerous investigators have studied various activities of natural products and have found that they have not only nutritional effects, but also beneficial properties to cure various diseases and to maintain good health. Job's Tear(Yul-Moo) is a grass crop that has long been used in traditional medicine and as a nourishing food. Although its mechanism of action remains unclear, Job's Tear has been reported to exhibit anti-inflammatory, stomachic, anti-allergic, and anti-spastic effects and has been used in China for the treatment of warts, rheumatism, and neuralgia. Previous results in our laboratory demonstrated that the ethanol extract and the water extract of Job's Tear exerted an immune regulatory function on mice cells in vitro. The present study was performed to investigate the ex vivo effect of Job's Tear on immune function. Seven to eight weeks old mice(Balb/c) were fed chow diet ad libitum and water extract of Job's Tear was administered orally every other day for four weeks at two different concentrations(50 and 500mg/kg B.W.). Splenocytes proliferation with mitogen stimulation with Con A and LPS was enhanced at 50 mg/kg B.W. of Job's Tear compared to those of the control group. The results of this ex vivo study showed that proliferation of splenocytes and macrophage activation were seen in the mice orally administrated 50 mg/kg B.W. of Job's Tear water extracts. In conclusion, this study suggests that Job's Tear extracts may enhance immune function by regulating splenocyte proliferation and the cytokine prodution capacity of activated macrophages in mice.

• The Journal of the Korean dental association
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• v.48 no.12
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• pp.893-918
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• 2010

This article is purposed of reviewing the development history of Japanese dental devices and instrument, and their related advertisement activities during the Japanese colonized period in Korea in early 20th century. Japanese dental devices and instrument were redesigned to accommodate their ergonomic shape above the simple imitation, and it implies the excessive desires brought them frustrations. The tragic earthquake on Sep. l, 1923, medical insurance law enforcement on Jan. 1, 1927, celebration of "Cavity prevention Day" started on Jun. 4, 1928, and the attack of Manchuria and China by Japan after 1931, all of these historical incidents become the preliminary requirement for the development of dental devices. On Nov. 1, 1937, Japanese government started to control dental materials, driving the campaigns for excluding foreign products and encourging the use of local products. In 1939, Nakajima dental manufacturers used this political and social atmosphere on their advertisement as saying "Our Nakajima's products have no compromise with the short raw materials, but only commitment to our quality". Since after 1940, the price and supply have been strongly under control, and the control group was appeared to manage all of supply and distribution of raw materials, regular price system, and specifications. At last, the Japanese national power were devastated in its production and distribution capacities, and get to the frustrated period. The main advertised dental devices and instruments in Korea during the Japanese colonized period were 1) dental chair, unit and cabinet, 2) dental x-ray, 3) compressors, 4) dental needles, 5) small instrument and carryon medical(emergency) kit, 6) oral hygiene and pyorrhea alveolaris, infrared rays, sunlight lamp, ultrashort wave treatment devices, 7)crown former, electric furnace, casting machine, articulator, electric lathe, and laboratory equipments, etc.

• Journal of Technologic Dentistry
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• v.22 no.1
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• pp.113-128
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• 2000

The purpose of this study was to serve as a basis for the development of dental technology and for creating a condition that dental technicians could work with pride and right values, by examining what problems there were in their health care, what they thought about them, and how the problems could be solved, The findings of this study were as below: 1. The most serious and harmful element in dental technology workshop was a dust(57.5%) and a noise(33.3%). 2. Approximately 99.0% of the dental technicians investigated made a complain of air pollution caused by noise. Their opinion on a possible measure to remove noise air pollution was that the noise-generating machine should be replaced(64.1%) or that it should be isolated(28.8%). 3. 76.0% complained air pollution cause by dust deteriorates their working efficiency. As a way to eliminate it, they suggested a dust chamber(35.3%) or an air cleaner(27.5%) should be installde. 4. About 80% made a complain of gas air pollution. The most common related symptom was a headache(56.9%). They thought that gas-generating machine should be isolated(39.9%) or that an air purifier should be prepared(33.3%). 5. The largest impact of heat and light on their body was weakening their eyesight(56.9%). 47.1% got burn once though four times, and 34.3% did five times or more. The way to prevent them was to install an automatic casting machine(66.0%) or use protective glasses(28.1%). 6. Approximately 47.7% were considering a change of occupation, and the most common reason was heavy work(23.5%), followed by poor prospect(21.6%) and working environment(19.0%) in the order named. 7. 88.9% responded they were likely to have an occupational disease. Their idea about the proper frequency of regular health examination was once a year(53.6%), or once per every six months(41.8%). 8. The field they were most interested in was health care(39.2%), followed by academic research activities(31.4%). This fact indicated it's most urgently required to improve their working environment.

• Advances in materials Research
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• v.9 no.3
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• pp.233-250
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• 2020

In this study, a chitosan based coating method was developed and applied on the shoe lining leather surface for evaluating its inhibition to bacterial and fungal attacks. At first, chitosan was prepared from raw prawn shells and then the prepared chitosan solution was applied onto the leather surface. Secondly, the characterization of the prepared chitosan and chitosan treated leather was performed by solubility test, ATR-FTIR, XRD pattern, SEM and TGA. Evaluation of antimicrobial efficacy of chitosan was assessed against two gram positive, two gram negative bacteria and a reputed fungi by agar diffusion test. The results of this study demonstrated that chitosan took place in both the surface of collagen fibres and inside the collagen matrix of crust leather. The chitosan showed strong antimicrobial activities against all the tested microorganisms and the inhibition increased with increasing percentage of chitosan. Therefore, the prepared chitosan in this study can be an environment friendly biocide, which functions simultaneously against different spoilage bacteria and fungi on the finished leather surface. Thus by using the prepared chitosan in shoe lining leather, the possibility of microbial attack during shoe wearing can be minimized which is one of the important hygienic requirements of footwear.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.1
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• pp.51-55
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• 2016

Phytochemical investigation of Pistacia integerrima has highlighted isolation of two known compounds naringenin (1) and dihydrokaempferol (2). A crude extract and these isolated compounds were here evaluated for their effects on reversion of multidrug resistance (MDR) mediated by P-glycoprotein (P-gp). The multidrug resistance P-glycoprotein is a target for chemotherapeutic drugs from cancer cells. In the present study rhodamine-123 exclusion screening test on human mdr1 gene transfected mouse gene transfected L5178 and L5178Y mouse T-cell lymphoma cells showed excellent MDR reversing effects in a dose dependent manner. In-silico molecular docking investigations demonstrated a common binding site for Rhodamine123, and compounds naringenin and dihydrokaempferol. Our results showed that the relative docking energies estimated by docking softwares were in satisfactory correlation with the experimental activities. Preliminary interaction profile of P-gp docked complexes were also analysed in order to understand the nature of binding modes of these compounds. Our computational investigation suggested that the compounds interactions with the hydrophobic pocket of P-gp are mainly related to the inhibitory activity. Moreover this study s a platform for the discovery of novel natural compounds from herbal origin, as inhibitor molecules against the P-glycoprotein for the treatment of cancer.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.10
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• pp.5233-5236
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• 2012

CK2 is a serine threonine kinase that participates in a variety of cellular processes with more than 300 defined substrates. This critical enzyme is known to be upregulated in cancers, but the role of this upregulation in carcinogenesis is not yet fully understood but c-myc, one of the defined CK2 substrates, is a well-known proto-oncogene that is normally essential in developmental process but is also involved in tumor development. We evaluated the optimal enzyme and substrate concentrations for CK2 activity in both neoplastic and non-neoplastic human lung tissues using the c-$myc^{424-434}$ peptide (EQKLISEEDL) as a substrate. The activities measured for the neoplastic tissue were 600-750 U/mg protein while those for the control tissue was in the range of 650-800 U/mg. $K_m$ value for c-myc peptide was determined as $0.33{\mu}M$ in non-neoplastic tissue and $0.18{\mu}M$ in neoplastic tissue. In this study, we did not observe an increased activity in the neoplastic tissue when compared with the non-neoplastic lung tissue, but we recorded two times higher affinity for c-$myc^{424-434}$ in cancer tissue. Considering the metabolic position of c-$myc^{424-434}$, our results suggest that phosphorylation by CK2 may be important in dimerization and thus it might affect the regulation of c-myc in cancer tissues.

• The Journal of the Korea Contents Association
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• v.5 no.5
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• pp.287-295
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• 2005

This paper describes user context awareness system, which is one of the most essential technologies in various application services of ubiquitous computing. The proposed system used two-akial accelerometer, embedded in SenseWear(R)PRO2 Armband (BodyMedia). When it was worn on the right upper arm of the experiment subjects, MAD (mean of absolute difference) value of the sensor data was calculated to quantify the amount of the wear's activity. Using this data, PC-based fuzzy inference system was realized to distinguish human motion states, such as, lying, sitting, walking and running and to recognize the restricted emergency situations. In laboratory experiment, the amount of activities for tying, sitting, walking and running were 0.204 g/s, 0.373 g/s, 2.808 g/s and 16.243 g/s respectively. The recognition rates of human motion states were 96.7 %, 93.0 %, 95.2 % and 98.4 % respectively for lying, sitting, walking and running. The recognition rate of restricted emergency situation was 100%.

• Nutritional Sciences
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• v.7 no.4
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• pp.241-246
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• 2004

This study investigated the influence of weight perception on weight management strategies including diet and exercise in Korean female adolescents. Junior (J) and senior (S) high school girls were divided in two groups; those who had $\leq$100% (BI) and > 100% (AI) of ideal weight (J-BI, n=376, 14.8 yr, 46.1 kg; J-AI, 11=128, 15.0 yr, 57.4 kg; S-BI, n=325, 17.4 yr, 50.1 kg; and S-AI, n=133, 17.5 yr, 58.2 kg, mean values). Questionnaires to assess weight perception, desire to lose weight, body image, eating behavior, weight control strategies and physical activity (PPA) were administered J-AI(9.4 kg) and S-AI(9.8 kg) desired to lose weight more than J-BI(2.5 kg) and S-BI(3.6 kg), respectively (p < 0.001). 85% of J-AI and 93% of S-AI perceived their weight being above average and 23% of J-BI and 34% of S-BI responded similarly (p < 0.001). Body dissatisfaction index (BDI) and eating attitude (EAT26) scores were lower in J-BI(9.7, 12.0) vs. J-AI(16.4, 14.7) and S-BI(12.4, 12.4) vs. S-AI(19.5, 15.4) (p < 0.001). However, PPA was not different for J-BI vs. J-AI, and S-BI vs. S-AL Only 17, 18, 9, and 15% of J.BI, J.AI, S-BI, and S-AI, respectively, exercised regularly. PPA and BDI were only slightly correlated in J-BI(r=0.194, p < 0.005) and S-BI(r=0.220, p < 0.005). Even that the majority of Korean female adolescents perceived they were heavy and desired to lose weight, appropriate exercise and physical activities were not practiced.

• The Korea Journal of Herbology
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• v.26 no.1
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• pp.119-124
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• 2011

Objective : This study was carried out to investigate effect of korean medicinal herbs-included hair tonic (MHT) and food (MF) on hair growth in an alopecia model of C57BL/6 mice. Methods : Six-weeks old mice were given laboratory rodent chow diet for 1 week. Then, we used a depilatory for hair removal on mice. The next day, mice were randomized and separated in 3 groups of 6 mice; normal group (N, vehicle epidermal application+normal diet-treated group), positive control group (C, 3% minoxidil sulfate epidermal application+normal diet-treated group), and the treatment group (T, HT epidermal application+ MF diet-treated group). The hair regrowth was determined by photograph, which was taken at 7, 14 and 21 days. And scoring indices, hair density and hair thickness, were evaluated by Folliscope at same day. In addition, the hair regrowth was analyzed insulin-like growth factor (IGF-1) in the dorsal skin of mice. Results : As a result, not only external appearance but also hair density and hair thickness on dorsal skin were increased more in C, T groups than in N group at 21 days with mixed treatment. Therefore, distinct regrowth pattern is appeared by treatment of herbal tonic and natural food for 21 days. Also, the expressions of IGF-1 on dorsal skin were higher in C, T groups than in N group. Conclusion : These results suggested that this herbal hair tonic and natural food has hair growth promoting activities and may be useful for treatment of bald or alopecia.