• Title/Summary/Keyword: knowledge generation

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The Trend of Cigarette Design and Tobacco Flavor System Development

  • Wu, Jimmy Z.
    • Journal of the Korean Society of Tobacco Science
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    • v.24 no.1
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    • pp.67-73
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    • 2002
  • In light of addressing consumer health concern, coping with anti-tobacco movement, and promoting new product, tobacco industry is actively pursuing to make a new generation of cigarettes with low tar and nicotine deliveries, and less harmful substances. Low tar and low nicotine cigarettes increases their market shares dramatically world wide, especially in KT&G, multinational tobacco companies, EU countries, even in China regulated by CNTC to set up yearly target to lower tar and nicotine deliveries. On the other hand, to design a new cigarette with reduced harmful substances begins to gain speed. The "modified Hoffmann list" publishes thirty plus substances in tobacco leaf and main smoke stream, which is the prime suspect causing health problems. Various ways and means are developed to reduce such components including new tobacco breeds, new curing method, tobacco leaf treatment before processing, selected filtration system, innovated casing system to reduce free radicals, as well as some non conventional cigarette products. In TSRC held this year, the main topic is related to reduce tobacco specific nitrosamines in tobacco leaf. The new generation of cigarette is in the horizon. It still needs a lot help to produce commercial products with satisfied taste and aroma characters. The flavor industry is not regulated by many governments demanding which ingredients might or might not be for tobacco use. However, most of the cigarette companies self impose a list of ingredients to guide flavor suppliers to design flavors. Unfortunately, the number of ingredients in those lists is getting shorter every year. It is understandable that the health is not the only reason. Some cigarette companies are playing safe to protect the company from potential lawsuit, while others are just copying from their competitors. Moreover, it is obvious that it needs more assistance from casings and flavors to design new generation of cigarettes with missing certain flavor components in tobacco leaf and main smoke stream. These flavor components are either non-existed or at lower level at new form of cured tobacco leaf or filtered in the main smoke stream along with reduced harmful substances. The use of carbon filters and other selected filtration system poses another tough task for flavor system design. Specific flavor components are missing from the smoke analysis data, which brings a notion of "carbon taste" and "dryness" of mouth feel. It is ever more demanded by cigarette industry to flavor suppliers to produce flavors as body enhancer, tobacco notes, salivating agents, harshness reducer, and various of aromatic notes provided they are safe to use. Another trend is that water based flavor or flavor with reduced ethanol as solvent is gaining popularity. It is preferred by some cigarette companies that the flavor is compounded with all natural ingredients or all ingredients should he GMO free. The new generation of cigarettes demands many ways of new thinking process. It is also vital for tobacco industry. It reflects the real needs for the consumers that the cigarette product should be safe to use as well as bearing the taste and aroma characters smokers always enjoyed. An effective tobacco flavor system is definitely a part of the equation. The global trend of tobacco industry is like trends of any other industries lead by consumer needs, benefited with new technology availability, affected by the global economy, and subjected for various rules and regulations. Anti-tobacco organizations and media exceptionally scrutinize cigarette, as a legal commercial product. Cigarette is probably the most studied commercial product for its composition, structure, deliveries, effects, as well as its new developmental trend. Therefore, any new trend of cigarette development would be within these boundaries. This paper is trying to point out what it would be like for tobacco industry in the next few yews and what concerns the tobacco industry. It focuses mostly on the efforts to produce safer cigarettes. It is such a vital task for the tobacco industry and its affiliate industries such as cigarette papers, filters, flavors, and other materials. The facts and knowledge presented in this paper might be well known for the public. Some of the comments and predictions are very much personal opinion for a further discussion.

Metagenomic Analysis of Jang Using Next-generation Sequencing: A ComparativeMicrobial Study of Korean Traditional Fermented Soybean Foods (차세대 염기서열 분석을 활용한 장류의 메타지놈 분석 : 한국 전통 콩 발효식품에 대한 미생물 비교 연구)

  • Ranhee Lee;Gwangsu Ha;Ho Jin Jeong;Do-Youn Jeong;Hee-Jong Yang
    • Journal of Life Science
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    • v.34 no.4
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    • pp.254-263
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    • 2024
  • Korean jang is a food made using fermented soybeans, and the typical products include gochujang (GO), doenjang (DO), cheonggukjang (CH), and ganjang (GA). In this study, 16S rRNA metagenome analysis was performed on a total of 200 types of GO, DO, CH, and GA using next-generation sequencing to analyze the microbial community of fermented soybean foods and compare taxonomic (biomarker) differences. Alpha diversity analysis showed that in the CHAO index, the species richness index tended to be significantly higher compared to the DO and GA groups (p<0.001). The results of the microbial distribution analysis of the GO, DO, CH, and GA products showed that at the order level, Bacillales was the most abundant in the GO, DO, and CH groups, but Lactobacillales was most abundant in the GA group. Linear discriminant analysis effect (LEfSe) analysis was used to identify biomarkers at the family and species levels. Leuconostocaceae, Thermoactinomycetaceae, Bacillaceae, and Enterococcaceae appeared as biomarkers at the family level, and Bacillus subtilis, Kroppenstedtia sanguinis, Bacillus licheniformis, and Tetragenococcus halophilus appeared at the species level. Permutational multivariate analysis of variance (PERMANOVA) analysis showed that there was a significant difference in the microbial community structure of the GO, DO, CH, and GA groups (p=0.001), and the microbial community structure of the GA group showed the greatest difference. This study clarified the correlation between the characteristics of Korean fermented foods and microbial community distribution, enhancing knowledge of microorganisms participating in the fermentation process. These results could be leveraged to improve the quality of fermented soybean foods.

A Study on the Effect of Technological Innovation Capability and Technology Commercialization Capability on Business Performance in SMEs of Korea (우리나라 중소기업의 기술혁신능력과 기술사업화능력이 경영성과에 미치는 영향연구)

  • Lee, Dongsuk;Chung, Lakchae
    • Korean small business review
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    • v.32 no.1
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    • pp.65-87
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    • 2010
  • With the advent of knowledge-based society, the revitalization of technological innovation type SMEs, termed "inno-biz" hereafter, has been globally recognized as a government policymakers' primary concern in strengthening national competitiveness, and much effort is being put into establishing polices of boosting the start-ups and innovation capability of SMEs. Especially, in that the inno-biz enables national economy to get vitalized by widening world markets with its superior technology, and thus, taking the initiative of extremely competitive world markets, its growth and development has greater significance. In the case of Korea, the government has been maintaining the policies since the late 1990s of stimulating the growth of SMEs as well as building various infrastructures to foster the start-ups of the SMEs such as venture businesses with high technology. In addition, since the enactment of "Innovation Promotion Law for SMEs" in 2001, the government has been accelerating the policies of prioritizing the growth and development of inno-biz. So, for the sound growth and development of Korean inno-biz, this paper intends to offer effective management strategies for SMEs and suggest proper policies for the government, by researching into the effect of technological innovation capability and technology commercialization capability as the primary business resources on business performance in Korean SMEs in the light of market information orientation. The research is carried out on Korean companies characterized as inno-biz. On the basis of OSLO manual and prior studies, the research categorizes their status. R&D capability, technology accumulation capability and technological innovation system are categorized into technological innovation capability; product development capability, manufacturing capability and marketing capability into technology commercialization capability; and increase in product competitiveness and merits for new technology and/or product development into business performance. Then the effect of each component on business performance is substantially analyzed. In addition, the mediation effect of technological innovation and technology commercialization capability on business performance is observed by the use of the market information orientation as a parameter. The following hypotheses are proposed. H1 : Technology innovation capability will positively influence business performance. H1-1 : R&D capability will positively influence product competitiveness. H1-2 : R&D capability will positively influence merits for new technology and/or product development into business performance. H1-3 : Technology accumulation capability will positively influence product competitiveness. H1-4 : Technology accumulation capability will positively influence merits for new technology and/or product development into business performance. H1-5 : Technological innovation system will positively influence product competitiveness. H1-6 : Technological innovation system will positively influence merits for new technology and/or product development into business performance. H2 : Technology commercializing capability will positively influence business performance. H2-1 : Product development capability will positively influence product competitiveness. H2-2 : Product development capability will positively influence merits for new technology and/or product development into business performance. H2-3 : Manufacturing capability will positively influence product competitiveness. H2-4 : Manufacturing capability will positively influence merits for new technology and/or product development into business performance. H2-5 : Marketing capability will positively influence product competitiveness. H2-6 : Marketing capability will positively influence merits for new technology and/or product development into business performance. H3 : Technology innovation capability will positively influence market information orientation. H3-1 : R&D capability will positively influence information generation. H3-2 : R&D capability will positively influence information diffusion. H3-3 : R&D capability will positively influence information response. H3-4 : Technology accumulation capability will positively influence information generation. H3-5 : Technology accumulation capability will positively influence information diffusion. H3-6 : Technology accumulation capability will positively influence information response. H3-7 : Technological innovation system will positively influence information generation. H3-8 : Technological innovation system will positively influence information diffusion. H3-9 : Technological innovation system will positively influence information response. H4 : Technology commercialization capability will positively influence market information orientation. H4-1 : Product development capability will positively influence information generation. H4-2 : Product development capability will positively influence information diffusion. H4-3 : Product development capability will positively influence information response. H4-4 : Manufacturing capability will positively influence information generation. H4-5 : Manufacturing capability will positively influence information diffusion. H4-6 : Manufacturing capability will positively influence information response. H4-7 : Marketing capability will positively influence information generation. H4-8 : Marketing capability will positively influence information diffusion. H4-9 : Marketing capability will positively influence information response. H5 : Market information orientation will positively influence business performance. H5-1 : Information generation will positively influence product competitiveness. H5-2 : Information generation will positively influence merits for new technology and/or product development into business performance. H5-3 : Information diffusion will positively influence product competitiveness. H5-4 : Information diffusion will positively influence merits for new technology and/or product development into business performance. H5-5 : Information response will positively influence product competitiveness. H5-6 : Information response will positively influence merits for new technology and/or product development into business performance. H6 : Market information orientation will mediate the relationship between technology innovation capability and business performance. H7 : Market information orientation will mediate the relationship between technology commercializing capability and business performance. The followings are the research results : First, as for the effect of technological innovation on business performance, the technology accumulation capability and technological innovating system have a positive effect on increase in product competitiveness and merits for new technology and/or product development, while R&D capability has little effect on business performance. Second, as for the effect of technology commercialization capability on business performance, the effect of manufacturing capability is relatively greater than that of merits for new technology and/or product development. Third, the mediation effect of market information orientation is identified to exist partially in information generation, information diffusion and information response. Judging from these results, the following analysis can be made : On Increase in product competitiveness, directly related to successful technology commercialization of technology, management capability including technological innovation system, manufacturing capability and marketing capability has a relatively strong effect. On merits for new technology and/or product development, on the other hand, capability in technological aspect including R&D capability, technology accumulation capability and product development capability has relatively strong effect. Besides, in the cast of market information orientation, the level of information diffusion within an organization plays and important role in new technology and/or product development. Also, for commercial success like increase in product competitiveness, the level of information response is primarily required. Accordingly, the following policies are suggested : First, as the effect of technological innovation capability and technology commercialization capability on business performance differs among SMEs; in order for SMEs to secure competitiveness, the government has to establish microscopic policies for SMEs which meet their needs and characteristics. Especially, the SMEs lacking in capital and labor are required to map out management strategies of focusing their resources primarily on their strengths. And the government needs to set up policies for SMEs, not from its macro-scaled standpoint, but from the selective and concentrative one that meets the needs and characteristics of respective SMEs. Second, systematic infrastructures are urgently required which lead technological success to commercial success. Namely, as technological merits at respective SME levels do not always guarantee commercial success, the government should make and effort to build systematic infrastructures including encouragement of M&A or technology trade, systematic support for protecting intellectual property, furtherance of business incubating and industrial clusters for strengthening academic-industrial network, and revitalization of technology financing, in order to make successful commercialization from technological success. Finally, the effort to innovate technology, R&D, for example, is essential to future national competitiveness, but its result is often prolonged. So the government needs continuous concern and funding for basic science, in order to maximize technological innovation capability. Indeed the government needs to examine continuously whether technological innovation capability or technological success leads satisfactorily to commercial success in market economic system. It is because, when the transition fails, it should be left to the government.

Data Modeling for Cell-Signaling Pathway Database (세포 신호전달 경로 데이타베이스를 위한 데이타 모델링)

  • 박지숙;백은옥;이공주;이상혁;이승록;양갑석
    • Journal of KIISE:Databases
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    • v.30 no.6
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    • pp.573-584
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    • 2003
  • Recent massive data generation by genomics and proteomics requires bioinformatic tools to extract the biological meaning from the massive results. Here we introduce ROSPath, a database system to deal with information on reactive oxygen species (ROS)-mediated cell signaling pathways. It provides a structured repository for handling pathway related data and tools for querying, displaying, and analyzing pathways. ROSPath data model provides the extensibility for representing incomplete knowledge and the accessibility for linking the existing biochemical databases via the Internet. For flexibility and efficient retrieval, hierarchically structured data model is defined by using the object-oriented model. There are two major data types in ROSPath data model: ‘bio entity’ and ‘interaction’. Bio entity represents a single biochemical entity: a protein or protein state involved in ROS cell-signaling pathways. Interaction, characterized by a list of inputs and outputs, describes various types of relationship among bio entities. Typical interactions are protein state transitions, chemical reactions, and protein-protein interactions. A complex network can be constructed from ROSPath data model and thus provides a foundation for describing and analyzing various biochemical processes.

A Study on Implementation of Writing Supporting System(ICWS) for Interactive Storytelling Contents (인터렉티브 스토리텔링 콘텐츠 저작지원도구 설계 및 구현에 관한 연구)

  • Lee, Eun Ryoung;Kim, Kio Chung
    • Journal of Digital Convergence
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    • v.11 no.2
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    • pp.263-269
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    • 2013
  • This research paper is applying Writing Supporting System on the previous research study about writing tool data model on interactive storytelling about family Story. Family story writing supporting system enables users to create text, images, videos and digital contents based on experimental knowledge collected from the first and second generations. The paper about studies on writing tool system on family story, aims to create documentary based high quality contents about each family members and family history. At the same time, overcome generation gaps and the lack of creation infrastructures. Throughout this process, the author will contribute to the expansion of creation devices which can be applied in other researches and writing tools.

Building More Secure Femtocell with Improved Proxy Signature (개선된 위임 서명 방식을 이용해서 더 안전한 펨토셀 환경 구축)

  • Choi, Hyoung-Kee;Han, Chan-Kyu;Kim, Seung-Ryong
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.24 no.1
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    • pp.75-86
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    • 2014
  • Demand for the femtocell is largely credited to the surge in a more always best connected communication conscious public. 3GPP defines new architecture and security requirement for Release 9 to deal with femtocell, Home eNode B referred as HeNB. In this paper, we analyze the HeNB security with respect to mutual authentication, access control, and secure key agreement. Our analysis pointed out that a number of security vulnerabilities have still not been addressed and solved by 3GPP technical specification. These include eavesdropping, man-in-the-middle attack, compromising subscriber access list, and masquerading as valid HeNB. To the best of our knowledge, any related research studying HeNB security was not published before. Towards this end, this paper proposes an improved authentication and key agreement mechanism for HeNB which adopts proxy-signature and proxy-signed proxy-signature. Through our elaborate analysis, we conclude that the proposed not only prevents the various security threats but also accomplishes minimum distance from use-tolerable authentication delay.

Comparative Comprehension of Men Learning by the Principles of Complex System and the Book of Changes (복잡계의 원리와 주역의 사유방식이 주는 교육에의 시사점)

  • Park, Hye jeong;Do, Yeong ae
    • Korean Educational Research Journal
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    • v.41 no.1
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    • pp.59-79
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    • 2020
  • Men learning has no fixed route. In other words, any route can be taken, which can also be seen in the structure of other "complex systems" discussed in modern society. It can also be examined through Yang's long-standing classic, The Book of Changes Men learning itself started from informal learning to become today's formal learning. As we look at the stages of human civilization's progress, we can quickly discover these stages of development. The issue of human beings has always been a topic of discussion, and these discussions are ongoing. Men learn through language and tools, technology and culture, and through philosophy, art, and religion to deal with their complex and diverse mental world. Through these various activities, learning is accomplished. This is not limited to the physical processes of one generation learning through inheriting knowledge; men's learning, a kind of mental process, has extended our life. This is why there is no other reason that men's minds and learning are always developing. This study is about how to learn in a complex and diversified modern society and to find out how to coexist with the principles of the "complex system" and The Book of Changes.

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Development of Subsurface Spatial Information Model with Cluster Analysis and Ontology Model (온톨로지와 군집분석을 이용한 지하공간 정보모델 개발)

  • Lee, Sang-Hoon
    • Journal of the Korean Association of Geographic Information Studies
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    • v.13 no.4
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    • pp.170-180
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    • 2010
  • With development of the earth's subsurface space, the need for a reliable subsurface spatial model such as a cross-section, boring log is increasing. However, the ground mass was essentially uncertain. To generate model was uncertain because of the shortage of data and the absence of geotechnical interpretation standard(non-statistical uncertainty) as well as field environment variables(statistical uncertainty). Therefore, the current interpretation of the data and the generation of the model were accomplished by a highly trained experts. In this study, a geotechnical ontology model was developed using the current expert experience and knowledge, and the information content was calculated in the ontology hierarchy. After the relative distance between the information contents in the ontology model was combined with the distance between cluster centers, a cluster analysis that considered the geotechnical semantics was performed. In a comparative test of the proposed method, k-means method, and expert's interpretation, the proposed method is most similar to expert's interpretation, and can be 3D-GIS visualization through easily handling massive data. We expect that the proposed method is able to generate the more reasonable subsurface spatial information model without geotechnical experts' help.

A Study on the Structural Analysis & Design Optimization Using Automation System Integrated with CAD/CAE (통합된 CAD/CAE 자동화 System을 이용한 구조 강도 해석 및 설계 최적화에 관한 연구)

  • Won June-Ho;Kim Jong-Soo;choi Joo-Ho;Yoon Jong-Min
    • Proceedings of the Computational Structural Engineering Institute Conference
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    • 2005.04a
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    • pp.55-62
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    • 2005
  • In this paper, a CAB/CAE integrated optimal design system is developed, in which design and analysis process is automated using CAD/CAE softwares, for a complicated model for which parametric modeling provided by CAD software is not possible. CAD modeling process is automated by using UG/OPEN API function and UG/Knowledge Fusion provided by Unigraphics. The generated model is transferred to the analysis code ANSYS in parasolid format. Visual DOC software is used for optimization. The system is developed for PLS(Plasma Lighting System), which is a next generation illumination system that is used to illuminate stadium or outdoor advertizing panel. The PLS system consists of more then 20 components, which requires a lot of human efforts in modeling and analysis. The analysis for PLS includes static load, wind load and impact load analysis. As a result of analysis, it is found that the most critical component is a tilt assembly, which links lower & upper body assembly. For more reliable analysis, experiment is conducted using MTS and compared with the Finite element analysis result. The objective in the optimization is to minimize the material volume under allowable stresses. The design variables are three parameters in the tilt assembly that are chosen to be the most sensitive in stress values of twelve parameters. Gradient based method and RSM(Response Surface Method) are used for the algorithm and the results are compared. As a result of optimization, the maximum stress is reduced by 57%.

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The Optimal Partition of Initial Input Space for Fuzzy Neural System : Measure of Fuzziness (퍼지뉴럴 시스템을 위한 초기 입력공간분할의 최적화 : Measure of Fuzziness)

  • Baek, Deok-Soo;Park, In-Kue
    • Journal of the Institute of Electronics Engineers of Korea TE
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    • v.39 no.3
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    • pp.97-104
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    • 2002
  • In this paper we describe the method which optimizes the partition of the input space by means of measure of fuzziness for fuzzy neural network. It covers its generation of fuzzy rules for input sub space. It verifies the performance of the system depended on the various time interval of the input. This method divides the input space into several fuzzy regions and assigns a degree of each of the generated rules for the partitioned subspaces from the given data using the Shannon function and fuzzy entropy function generating the optimal knowledge base without the irrelevant rules. In this scheme the basic idea of the fuzzy neural network is to realize the fuzzy rule base and the process of reasoning by neural network and to make the corresponding parameters of the fuzzy control rules be adapted by the steepest descent algorithm. According to the input interval the proposed inference procedure proves that the fast convergence of root mean square error (RMSE) owes to the optimal partition of the input space