• Journal of muscle and joint health
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• v.11 no.2
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• pp.119-126
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• 2004

Purpose: The purpose of this study was to identify health problem and joint bleeding, disability according to severity in patients with hemophilia. Method: The research design was survey study for conformed severity in patients with hemophilia, health problem and bleeding of joint and degree of limitation. The subjects were 186 men in patients with hemophilia by convenience sampling. These results were analyzed statistically by frequency, percentage, t-test, chi-square. Result: 1. Health problem of severe hemophilia patients were significantly higher than moderate group(t=3.17, p=.002). A severe hemophilia patients were significantly higher than moderate group in health problem of socio-psychological, emotional, physical, interpersonal. 2. There was relation between severity and the frequency of bleeding($X^{2}=7.642$, p=.054). 3. A severe hemophilia patients were more than moderate group in disability of ankle joint(t=2.52, p=.013). Conclusion: A severe hemophilia patients has more severe problems than moderate patient in case of health problem, joint bleeding and degree of disability.

• Journal of Korean society of Dental Hygiene
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• v.17 no.4
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• pp.601-611
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• 2017

Objectives: The purpose of this study is to identify the perceived symptoms of oral and temporomandibular joint disorders in adults and to analyze the factors affecting subjective symptoms of temporomandibular joint disorders. Methods: 249 adults over 20 years old who had subjective symptoms of temporomandibular joint disorders were surveyed and analyzed. Independent t-test and ANOVA test were used to examine the relationship between oral habits and temporomandibular joint disorder according to general characteristics. $Scheff{\acute{e}}$ test was used for post-hoc analysis. Multiple regression analysis was conducted to examine the factors affecting oral habits and temporomandibular joint disorder. Results: First, the factors affecting oral and habitual behaviors were married (p<0.05) and monthly income between 1 million~1.9 million won (p<0.001), higher temporomandibular joint disorder (p<0.01) And the degree of habit was increased. Second, the factors affecting temporomandibular joint disorder were increased in occupation (p<0.05) and the degree of oral habit (p<0.01). Conclusions: In conclusion, it was confirmed that oral habit influences temporomandibular joint disorder. Especially, it is suggested that prevention and promotion of temporomandibular joint disorder are needed to recognize the removal of oral habits.

• Research in Community and Public Health Nursing
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• v.28 no.1
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• pp.55-68
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• 2017

Purpose: The purpose of this study is to develop and evaluate a joint health self-management program for knee osteoarthritis elders in communities. Methods: This program was developed based on the IMB (information-motivationbehavioral skills) model. The program methods include education, setting and achieving goals, sharing experiences, telephone counseling, and self-monitoring. The topics of the program include joint assessment, exercise, massage, joint protection, medication, depression management, diet, and healthcare approach. The research was conducted following the principles of the nonequivalent control group pretest-posttest design. Participants were 26 subjects in the experimental group, and 27 subjects in the control group. The experimental group participated in the self-management program, and the control group received general education. Results: Both post-test scores of personal motivation, social motivation, behavior skill, self-management behavior, joint pain, joint stiffness, physical function disability, right knee extension, left knee extension, and depression were significantly different between the experimental group and the control group. Conclusion: The results of the study can be used to develop and standardize a systematic joint health self-management program. Further research is highly recommended to develop a strategy to continuously facilitate self-management of osteoarthritis patients' procedures.

• Journal of Ginseng Research
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• v.47 no.4
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• pp.543-551
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• 2023

Background: Panax ginseng Meyer is a representative Chinese herbal medicine with antioxidant and anti-inflammatory activity. 20(S)-Protopanaxadiol (PPD) has been isolated from ginseng and shown to have promising pharmacological activities. However, effects of PDD on pulmonary fibrosis (PF) have not been reported. We hypothesize that PDD may reverse inflammation-induced PF and be a novel therapeutic strategy. Methods: Adult male C57BL/6 mice were used to establish a model of PF induced by bleomycin (BLM). The pulmonary index was measured, and histological and immunohistochemical examinations were made. Cell cultures of mouse alveolar epithelial cells were analyzed with Western blotting, coimmunoprecipitation, immunofluorescence, immunohistochemistry, siRNA transfection, cellular thermal shift assay and qRT-PCR. Results: The survival rate of PPD-treated mice was higher than that of untreated BLM-challenged mice. Expression of fibrotic hallmarks, including α-SMA, TGF-β1 and collagen I, was reduced by PPD treatment, indicating attenuation of PF. Mice exposed to BLM had higher STING levels in lung tissue, and this was reduced by phosphorylated AMPK after activation by PPD. The role of phosphorylated AMPK in suppressing STING was confirmed in TGF-b1-incubated cells. Both in vivo and in vitro analyses indicated that PPD treatment attenuated BLM-induced PF by modulating the AMPK/STING signaling pathway. Conclusion: PPD ameliorated BLM-induced PF by multi-target regulation. The current study may help develop new therapeutic strategies for preventing PF.

• Korean Journal of Occupational Health Nursing
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• v.7 no.1
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• pp.97-114
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• 1998

The occupational health services for the minor enterprises are poor comparing with that of large enterprises in Korea. In 1997, Korean government announced officially the law on joint employment system of occupational health practitioners to solve the problems. This study is to develop the model on the joint employment system of occupational nurse practitioners for minor enterprises in Korea based on the opinions of occupational health nurses (OH Ns). The data were collected by questionnares from October to November in 1997. The number of subjects was 210 occupational health nurses who had participated the mandatory nursing education program provided by the Korean Occupational Health Nurses Association(KOHNA). The response rate was 47.1%. The contents of questionnaires were general characteristics, occupational & job characteristics of OHNs, and the views on the joint employment system. The SAS-PC program was used for the statistical analysis. The results were as followed, (1) The proper number of industies was 3 and the appropriate number of workers was 448 for one joint employed occupational nurse practitioner (J EONP). (2) 44.7% of the OHNs wanted that the Ministry of Labor monitored the way and content of contraction b/w JEONP and minor emterprises, 82.6% of the OHNs wanted that KOHNA managed the employment informations. (3) The OHNs of occupational health agencies showed more positive attitude than the OHNs of private industries on the joint employment system. (4) 88.3% of the OHNs wanted the education training for JEONP. Especially in occupational hygiene and safety control. (5) The OHNs expected the role expansion of Occupational Health Nursing by JEONP system. At the same time they worried the adverse effects. For the successful execution of this system, it is necessary the cooperation among the Ministry of Labor, KOHNA, the minor enterprises, and the OHNs.

• Biomedical Science Letters
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• v.28 no.1
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• pp.1-8
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• 2022

Total joint arthroplasty is a successful joint replacement treatment that improves joint function and overall quality of life and provides pain relief. However, the prevalence of periprosthetic joint infection (PJI) has become prevalent with the rise in the incidence of arthroplasty surgery. PJI occurs rarely following arthroplasty however presents with serious complications, including high morbidity. The identification of causative microorganisms is essential for the treatment of PJI. Managing PJI requires complex treatment strategies, including long-term antibacterial treatment, and significant medical costs can be incurred. The American Academy of Orthopedic Surgeons, the Centers for Disease Control and Prevention, and Surgical Care Improvement Project guidelines recommend that prophylactic antibiotics such as first-generation cephalosporins be infused completely 1 hour before surgical incision. However, these preventative antibiotics are very limited, therefore risk factors must be identified to diagnosis and treat patients effectively. Moreover, determining antimicrobial susceptibility during artificial joint surgery and choosing the most appropriate treatment strategy following an accurate diagnosis of microbial infections are essential. In the present review, we describe the management, including the etiology, diagnosis, and classification of PJI, and approaches to its diagnosis using the available novel molecular diagnostic methods.

• Journal of muscle and joint health
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• v.15 no.1
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• pp.24-32
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• 2008

Purpose: This study was conducted to develop an advanced aquatic exercise program for the patients with arthritis. Method: This study subjects were six aquatic exercise program instructors of Korean Society Muscle and Joint Health. They withheld several meeting to develop advanced aquatic exercise program. Results: The basic aquatic exercise program which were used since 1996 in Korea consisted of 9 units of ROM exercise in water. The advanced aquatic exercise program for the patients with arthritis consist of 12 units with complex and resistive exercise. Conclusion: This preliminary advanced aquatic exercise program for the patients with arthritis should be investigate for the effectiveness to build a more concrete evidence and utilization.

• Research in Community and Public Health Nursing
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• v.12 no.2
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• pp.344-360
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• 2001

A quasi-experimental study was conducted to investigate the effects of health promotion program on health of the clients with arthritis. In this study. the health promotion program consisted of self appointment and confirmation. discussion, health education. group counsel, and exercise. And the program focused on self - help group meeting. A total of 68 subjects was randomly assigned into either the control group(n = 24) or the intervention group(n =44). The results of the study analyzed using a SPSS win, were as follows: 1) In physical function of physical health. there was a significant improvement in flexibility of the shoulder joint(hold the hand upward and downward behind the back). sit and reach, extension of the knee joint in the intervention group, compared to the control group, while no difference in flexibility of the shoulder joint(raising the arm), flexion of the knee joint, and grip strength. There was a significant improvement in physical functional disability in the intervention group, compared to the control group, but no difference in fatigue and pain. 2) The health promotion program resulted in improvement in psychosocial health(e.g. increase of self-efficacy and decreases of social functional disability) in the intervention group, compared to the control group. It was concluded that the health promotion program(weekly session for 6 weeks) employed in this study was appropriate for the clients with arthritis in primary health care center and had a positive effect on health in general.

• Journal of muscle and joint health
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• v.23 no.3
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• pp.152-158
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• 2016

Purpose:The purpose of this study was to examine the degree of joint pain, limitation of daily activities, and frequency of outpatient visits. Methods: This secondary analysis study used the data from the fifth Korean National Health and Nutrition Examination Survey (KNHNES). The data about general characteristics, prevalence and treatment of osteoarthritis, limitation of activities of daily living (ADL) and frequency of outpatient visits and hospitalization in 424 osteoarthritis patients over 50 years old were derived from the database. Data were analyzed with complex samples in SPSS ver. 20.0. Results: Among people with knee joint pain, 79.3% reported they had more than 4 out of 10 points of the degree of pain. Meanwhile, 97.3% of people with hip joint pain reported that they had more than 4 out of 10 points of the degree of pain. People reporting 10 out of 10 point of pain were 21.4% of those with knee joint pain and 25% of those with hip joint pain. The mean of the degree of knee joint pain was 6.35, and the mean of the degree of hip joint pain was 6.89 out of 10 points. About 50% of people with osteoarthritis visited an outpatient clinic within the last 2 weeks, and 27% had limitation of ADL. Conclusion: It is necessary to develop an integrated intervention program to improve quality of life in patients with osteoarthritis.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.2
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• pp.381-387
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• 2020

This study investigates the effects of mental health and daily oral habits on temporomandibular joint symptoms. The study was conducted from September 1 to 30, 2019, enrolling a total of 402 young adults. We determined that mental health levels of anxiety, depression, and social maladjustment are significantly different, depending on life satisfaction (p<0.001), subjective health status (p<0.001), and trauma (p<0.01). Treating jaw joints exerted a significant difference in social maladjustment (p<0.05). Temporomandibular joint symptoms are significantly higher among women (p<0.05), drinkers (p<0.01), trauma (p<0.01) and jaw joint treatment patients (p<0.001). Mental health levels (p<0.001), oral habits (p<0.001), and temporomandibular joint symptoms (p<0.001) are all positively correlated. In addition, oral hygiene has the greatest influence on temporomandibular joint symptoms of trauma. Furthermore, factors experienced during treatment of the jaw joints also affect the temporomandibular joint symptoms. We conclude that it is imperative to improve oral health and malpractice in treating jaw joint disorders, and also develop a program that effectively improves jaw joint health, by combining mental health counseling and daily lifestyle improvements.