• Development and Reproduction
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• v.21 no.4
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• pp.441-448
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• 2017

Bisphenol-A(BPA) is a member of alkylphenol family, and shows adverse effects including reduced fertility, reproductive tract abnormalities, metabolic disorder, cancer induction, neurotoxicity and immunotoxicity. In the present study, we conducted Hershberger assay to evaluate whether the two candidates to replace BPA have androgenic or antiandrogenic activity. The assay was carried out using immature castrated Sprague-Dawley male rats. After 7 days of the surgery, testosterone propionate (TP, 0.4 mg/kg/day) and test materials (low dose, 40 mg/kg/day; high dose, 400 mg/kg/day) were administered for 10 consecutive days by subcutaneous (s.c.) injection and oral gavage, respectively. Test materials were BPA, isosorbide (ISO) and cyclohexanedimethanol (CHDM). The rats were necropsied, and then the weights of five androgen-dependent tissues [ventral prostate, seminal vesicle, levator ani-bulbocavernosus (LABC) muscle, paired Cowper's glands, and glans penis] and three androgen-insensitive tissues (kidney, spleen and liver) were measured. All test materials including BPA did not exhibit any androgenic activity in the assay. On the contrary, antiandrogen-like activities were found in all test groups, and the order of the intensity was CHDM > BPA > ISO in the five androgen-sensitive tissues. There was no statistical difference between low dose treatment and high dose treatment of BPA group as well as ISO group. In CHDM group, high dose treatment exhibited most severe weight reduction in all measured tissues. There was no statistical difference in androgen-insensitive tissue measurements, except BPA groups. Since the effects of ISO treatment on the accessory sex organs were much less or not present at all when compared to those of BPA, ISO could be a strong candidate to replace BPA. CHDM treatment brought most severe weight reduction in all of androgen-sensitive tissues, so this material should be excluded for further screening of BPA substitute selection.

• Journal of Digital Convergence
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• v.14 no.11
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• pp.181-191
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• 2016

The purpose of this study is to analyze the management performance of the companies in the auto parts production requirements of new management techniques ISO9001 quality management system requirements for management innovation perspective in convergence age. For this purpose, we conducted a survey visiting the auto parts manufacturers. The results were as follows. First, among the details of the four key requirements of the ISO 9001 quality management systems in small and medium component suppliers, managers and responsible resource management showed a positive impact on business performance. In addition, based on the results of the investigation of the differences by grade, the higher rank group executive responsibilities, sub-grade group showed a low awareness of the quality management according to ISO 9001. This will contribute to establishing the guidelines and Improvement Consulting Strategies to improve productivity in small and medium automotive rubber bellows automotive parts production.

• Journal of the Korea Society of Computer and Information
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• v.3 no.4
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• pp.174-192
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• 1998

These day in the Quality Assurance System, it required that computer system is able to utilize SQC and ISO 9000 series, just then. However. because SQC is necessary to special branch of statistical experience, it is very hard to use and have a bound in that apply to practical business. Therefor in this paper, we proposed the software system which is control, at the same time, SQC and ISO 9000 series, in addition to avail without statistical knowledge. For the shake of this point, the substance of this study is largely separated dual part that ISO 9000 system for which is limited to use design of basic system, test, experiment, tracking incongruent part, analysis condemned goofs, and SQC system for which is to limited to use control chart, estimate, statistical testing, design of experiment(DOE) which used to commonly in Quality Control System. Expected efficiency of this paper is to set Qualify Management System, transfer qualify consciousness, satisfy the customer, increase reliability, in particular, it is expected that it is very useful to minor enterprises of manufacturing-centered.

• Journal of the Korean Wood Science and Technology
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• v.44 no.1
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• pp.147-155
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• 2016

Pulp made from sugarcane bagasse (SCB) was bleached in element chlorine free (ECF) sequence. The peroxide bleaching process for the final bleaching process has been introduced in order to reduce the use of chlorine dioxide. Prior to peroxide bleaching, different chelating chemicals were applied. When 4.5% of the total chlorine dioxide was used, bleached SCB pulp using additional DTPA chelate stage (DEDQP) resulted in 87.0% of the ISO brightness. However, bleached pulp using simultaneous stage of DTPA chelate and chlorine dioxide (DE(DQ)P) was reached at 83.9% of the ISO brightness. The viscosity of DEDQP bleached pulp was 25.6 cPs, and the one of DE(DQ)P bleached pulp was 21.9 cPs. Decreasing of chelate effect by chlorine dioxide led to a decrease in the final brightness and a lower viscosity. But simultaneous stage of EDTA chelate and chlorine dioxide (DE(DQ)P) led to higher final brightness (87.0% ISO) and higher viscosity (25.8 cPs) than those of the $DEDQ_{EDTA}P$ bleached pulp (86.4% ISO, 25.2 cPs).

• Tuberculosis and Respiratory Diseases
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• v.40 no.5
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• pp.540-547
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• 1993

Backgrounds: The measurement of volume of isoflow has been considered as a sensitive test for detecting small airway diseases showing normal pulmonary function in a routine pulmonary function test. To evaluate the functions of small airway among dust exposed workers, the changes of volume of isoflow were measured and its applicability of managing early stage pneumoconiosis patients was studied. Method: The subjects were 67 male, pneumoconiosis with small opacity and FEV1>80%, FEV1/FVC>75% in spirometry and the controls were 20 male, no dust-exposed office workers. The maximal epiratory volume curves after inhalation of indoor air and $He-O_2$ gas mixtures were measured and ${\Delta}V_{max50},\;{\Delta}V_{max75},\;V_{iso}V/VC$ between the dust exposed and control workers were compaired. Results: 1) There were no significant differences between two group in ${\Delta}V_{max50}$ and ${\Delta}V_{max75}$. But the ratio of $V_{iso}V/VC$ of the subjects was siginificantly higher than that of the control (p<0.01). This study confirms that $V_{iso}V/VC$ is a very useful index in early detection of small airway dysfunction. 2) The ratio of $V_{iso}V/VC$ of the subjects was signigicantly different between only smoker group and mixed group(smoker and nonsmoker). It suggestes that smoking is an important cousative factor of small airway dysfunction. 3) As the profusion of the chest X-ray increased, the rartio of $V_{iso}V/VC$ increased, but no significant difference of $V_{iso}V/VC$ was found between categories of pneumoconiosis. The categories of pneumoconiosis and small airway dysfunction may not be related. 4) No significant relationship was established between the duration of work and the ratio of $V_{iso}V/VC$. Conclusions : It is concluded that the measurement of $V_{iso}V/VC$ is useful to detect small airway dysfuction of early stage pnuemoconiosis patents with small opacities but showing normal pulmonary function in a routine pulmonary function test.

• Journal of KIISE:Software and Applications
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• v.27 no.12
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• pp.1155-1162
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• 2000

ISO/IEC 14598-4(소프트웨어 제품의 구매자 평가 지침)는 소프트웨어 평가에서 무결성 수준의 중요성을 전제로 품질특성의 우선순위를 제시하고 있다. 그러나 이러한 제시는 현실에 적용한 것이 없는 이론적인 것이다. 본 연구에서는 ISO/IEC 14598-4에서 제시한 무결성 수준에 따른 품질특성의 중요도가 타당성이 있는지를 실증하였다. 중요도 산출을 위해 15명을 면담 조사하였으며, 이는 중요도 계산을 위한 AHP를 활용하기에 충분한 표본의 개수이다. 본 연구결과와 ISO/IEC 14598-4에서 제시한 품질특성의 중요도 순위는 일부가 상이하게 나타났다. 또한 척도를 이용한 소프트웨어 품질경영을 시작할 때 통상적으로 권고되는 척도의 수 범위(최소 4개~최대 8개) 내에서 무결성 수준에 관계없이 동일한 척도가 선정되었다.

• Journal of Korean Tunnelling and Underground Space Association
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• v.16 no.3
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• pp.311-320
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• 2014

High strength concrete is not only vulnerable to the occurrence of spalling which generates the loss of cross-section in concrete structures but produces faster degradation in its mechanical properties than normal strength concrete in the event of fire. This study aims to evaluate fire resistance of high strength segment concrete with PET fibers mixed to prevent spalling under ISO834 (2hr) and RABT fire curve. As results, the samples without PET fibers show the concrete loss up to the depth of about 8 cm and 9.5 cm from the surface exposed to fire under ISO834 and RABT fire curve respectively. The samples mixed with PET fiber of 0.1% show no spalling under ISO834 fire curve and the spalled thickness of 6.5 cm under RABT fire curve after the fire tests. Finally, the sample mixed with PET fiber of 0.2% shows no spalling under RABT fire curve. The results indicate that the suitable amounts of PET fiber for securing fire resistance performance of this high strength segment concrete are 0.1% under ISO834 fire curve and 0.2% under RABT fire curve. However, even though spalling does not occur, it is necessary to repair the deterioration of concrete up to 4 cm from the surface exposed to fire after fire.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.13 no.5
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• pp.17-26
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• 2013

ISO/IEC 29157 originally developed in the Republic of Korea and is based on commercially available PicoCast v1.0. ISO/IEC JTC1 SC6 was registered by the international standard on May 2010. A single platform for a variety of applications and media formats to support development objectives were. ISO/IEC 29157 based wireless networks, ie, Pico-net to master node periodically transmit sync signal is synchronized to the number of slave nodes have the communications structure. Pico-net also supports a variety of network topologies and direct communication between nodes(single-hop communication) and QoS is guaranteed. But Pico-net network structure has the following problems. Loss of communication problems due to mobile nodes, resulting in limitations of node mobility and wireless network operation range of conventional wireless networks operating range less than 1/4 was reduced to the problem. In this paper, a possible solution to the problems mentioned is proposed, using multi-hop communication technology and sync signal transmission technology between nodes.

• The Monthly Technology and Standards
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• s.114
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• pp.42-45
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• 2011

ISO TC 184/SC 2 로봇과 로봇장치 분과의 4개 작업그룹회의가 미국 LA에서 열렸다. 우리나라는 5개의 작업그룹 중에서 WG 1과 WG 8의 컨비너를 수임하고 있는 등 서비스로봇 분야 표준화활동을 주도하고 있다. 문승빈 세종대학교 컴퓨터공학과 교수의 참관기를 싣는다.

• Proceedings of the Korean Information Science Society Conference
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• 2003.04c
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• pp.4-6
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• 2003

디자인 패턴과 안티 패턴의 원리는 혼합되어 사용되어진다. 디자인 패턴은 소프트웨어 품질에 대하여 공격적인 예방치료에 목적을 두며, 안티 패턴은 품질 이슈에 대하여 체계적인 진단을 수행하는 것이다. 품질에 대한 국제 표준으로는 ISO/IEC 9126, ISO/IEC 12119등이 있다. 최근에는 이러한 품질에 관련된 문제점들을 해결하기 위하여 디자인 패턴과 안티 패턴에 대한 연구가 활발히 이루어지고 있다. 본 논문에서는 현재 대표적으로 사용되어지는 디자인 패턴과 안티 패턴을 ISO/IEC 9126의 품질 특성별로 분류하고 이들간의 상호 연관성에 대하여 연구하였다.