• Title/Summary/Keyword: internal responses

검색결과 765건 처리시간 0.03초

분심기음의 항암작용 및 면역기능에 관한 연구 (Experimental Studies on Antitumor Effect and Immune Responses of Bunsimgieum)

  • 김진성;윤상협;류봉하;류기원;여대원
    • 대한한방내과학회지
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    • 제24권2호
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    • pp.315-328
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    • 2003
  • This study was performed to investigate the effect of Bunsimgieum on antitumor effect after sarcoma-180 cells transplantation into peritoneal cavity or left groin and immune responses on the depressed immunity induced by methotrexate in mice. The Bunsimgieum extract of 10mg/kg was orally administered 14 days for antitumor effects and 21 days for immune responses. 50% inhibitory concentration($IC_{50}$) of SUN-1, SUN-C4, and SUN-396 cancer cell, mean sunvival days and body weight of tumor bearing mice, and growth of tumor mass for antitumor effect; delayed type hypersentivity, hemagglutinin titer, hemolysis titer, rosette forming cells, natured killer cell activity, lymphocyte transformation, productivity of interleukin-2, and phagocytic activity for their immune responses were measured in ICR mice. Significance in antitumor effect is noted in the enlongation of mean life days and inhibition of tumor growth(p<0.01, respectively). Significance of immune responses is also noted in hemolysis titer, lymphocyte transfumotion, IL-2 productivity, phagocytic activity, and natural killer cell activity at E/T ratio 100:1(p<0.01, respectively). Significant in rosette cell formation was seen at dosage of 20mg/kg(p<0.01). However, Difference of body weight as antitumor effect, delayed type hypersensitivity, and hemagglutinin titer were not shown significantly. According to the above results, it could be suggested that Bunsimgieum has prominent antitumor and immunity enhancing effect.

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치과 의료기관의 서비스스케이프와 인적서비스품질이 환자의 내적반응 및 행동의도에 미치는 영향 (The Effect of Servicescape and Human Service Quality on Patients' Internal Responses and Their Behavioral Intention in Dental Care Organizations)

  • 천미옥;김지원;배성윤
    • 한국병원경영학회지
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    • 제22권4호
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    • pp.1-15
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    • 2017
  • This study was designed to analyze the effect of servicescape and human service quality on patients' internal response and their behavioral intention in dental care organizations. Self-administered survey questionnaires with structured instruments were developed, and a total of 226 responses were used for statistical analyses using SPSS Windows version 18.0 program and AMOS 18.0 program. Major findings of the study are as follows. First, among other servicescape components, air condition environment was found to have a positive effect on patients' cognitive and physiological responses, while signals and symbols had a positive effect on cognitive and emotional responses. Second, the competence, among other factors of the human service quality, had positive influence on cognitive and emotional responses, while customer understanding affected positively on emotional response. Third, none of the servicescape components showed a direct effect on patients' behavioral intention, but their influence was mediated by internal responses. However, customer understanding, among other human service quality factors, had a direct effect on patients' behavioral intention. Fourth, emotional response, among other internal response factors, proved to have positive influence on behavioral intention. Results from this study suggest that dental care service providers can increase their competitiveness and customer satisfaction by understanding and improving the most important areas of servicescape and human service quality.

외식업체 근로자의 내부마케팅과 식품 안전분위기의 관계 및 고용형태의 조절효과 (The relationship between internal marketing and food safety, and the moderating effect of employment type in food service industry)

  • 안관영;배중남
    • 대한안전경영과학회지
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    • 제15권2호
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    • pp.151-159
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    • 2013
  • This paper reviewed the relationship between internal marketing(management support, education, pay system, internal communication, employment security) and food safety climate(prevention, superior attitude, work condition), and the moderating effect of employment type(permanent or temporary employees) in food service company. Based on the responses from 304 responses, the results of hierarchical multiple regression analysis showed that 4 factors(management support, education, internal communication, employment security) effect positively on food safety climate(prevention, superior attitude, work condition). The positive effect of internal communication on superior attitude and work condition appeared to be more positive in permanent employees than in temporary employees. And the results of t-test analysis showed that permanent employees perceived more positively all internal marketing factors(management support, education, pay system, internal communication, employment security) and food safety climate(precaution, superior attitude, work condition) than temporary employees.

의복구매 의사결정과정의 가격탐색에 따른 가격반응 유형 (Types of Consumer Responses to Price Based on Price Search)

  • 윤남희;이은영
    • 한국의류학회지
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    • 제34권8호
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    • pp.1403-1414
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    • 2010
  • Consumer decisions and responses about the price to pay vary. Some consumers might decide the appropriate price range prior to shopping, while others compare and evaluate prices. Especially, consumers can have different reference points for price evaluation based on various price searching behavior that represent heterogeneous responses for prices in the clothing purchase decision-making process. This research identifies how consumers evaluate the price and helps explain their decision-making based on price searches. By analyzing qualitative research, we found that consumers recalled price information as a representative indicator and product level price information through the internal search. Their level of internal references can be an important factor affecting price evaluations. In addition, each consumer groups were subdivided into high and low external searching. The four types of responses to price were classified in the price search process and the identified differences in the price evaluation. Therefore, pricing strategy needs to be differentiated for these various consumer types.

Characteristics of wind loading on internal surface and its effect on wind-induced responses of a super-large natural-draught cooling tower

  • Zou, Yun-feng;Fu, Zheng-yi;He, Xu-hui;Jing, Hai-quan;Li, Ling-yao;Niu, Hua-wei;Chen, Zheng-qing
    • Wind and Structures
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    • 제29권4호
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    • pp.235-246
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    • 2019
  • Wind loading is one of important loadings that should be considered in the design of large hyperbolic natural-draught cooling towers. Both external and internal surfaces of cooling tower are under the action of wind loading for cooling circulating water. In the previous studies, the wind loads on the external surface attracted concernedly attention, while the study on the internal surface was relatively ware. In the present study, the wind pressure on the internal surface of a 220 m high cooling tower is measured through wind tunnel testing, and the effect of ventilation rate of the packing layer on internal pressure is a major concern. The characteristics of internal wind pressure distribution and its effect on wind-induced responses calculated by finite element method are investigated. The results indicate that the wind loading on internal surface of the cooling tower behaves remarkable three-dimensional effect, and the pressure coefficient varies along both of height and circumferential directions. The non-uniformity is particularly strong during the construction stage. Analysis results of the effect of internal pressure on wind-induced responses show that the size and distribution characteristics of internal pressure will have some influence on wind-induced response, however, the outer pressure plays a dominant role in the wind-induced response of cooling tower, and the contribution of internal pressure to the response is small.

Seismic responses of hyperbolic cooling towers under horizontal and vertical earthquake

  • Zhang, Jun-Feng;Wang, Yuan-Hao;Li, Jie;Zhao, Lin
    • Earthquakes and Structures
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    • 제20권4호
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    • pp.405-415
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    • 2021
  • Following the dynamic property analysis and elaboration, linear response spectrum analysis (RSA) and response history analysis (RHA) were conducted on a representative hyperbolic cooling towers (HCT) in present study. The seismic responses in tower shell were illustrated in detail, including the internal force amplitude, modal contribution, influence from damping ratio, comparison of results got from RSA and RHA and especially the latitude distributions of internal forces. The results show that the eigenmodes could be classified in a new method into four types according to their mode shapes and only the lateral bending modes and vertical stretching modes are meaningful for horizontal and vertical earthquake correspondingly. The bending modes and seismic deformation display the same feature which is global lateral bending accompanied by minute circular flow displacement of section. This feature also decides the latitude distributions of internal forces as sine or cosine. Moreover, the following method is also proposed for approximate estimation of internal force amplitudes without time-consuming response history analysis: getting the response spectrums of the selected ground accelerations and then comparing values of response spectrums at the natural period of first lateral bending mode because it is always prime dominant for horizontal seismic responses.

호텔 주방의 지각된 물리적 환경이 조리 종사자의 내적 반응에 미치는 영향 (The Effect of the Perceived Physical Environments of Hotel Kitchens on Cooking Employees' Internal Responses)

  • 허준;유택용
    • 한국조리학회지
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    • 제14권4호
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    • pp.217-231
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    • 2008
  • The purpose of this study is to examine how the perceived physical environments of hotel kitchens influence cooking employees' internal responses. According to the analysis results of this study, except Hypothesis 2 which was rejected in this study, all the hypotheses were partially accepted. These results support the research hypotheses of this study that comfort, spatiality, and convenience as physical environments will have significant effects on emotional response and cognitive response. Also, equipment use as convenience had statistically significant effects on both emotional response and cognitive response whereas working environment as comfort and kitchen circulation and working space as spatiality had no effect. Therefore, kitchen environment should be set up in the direction of guaranteeing kitchen convenience to the maximum, and the further researches on the constituent factors which have no effect on emotional response and cognitive response should be proceeded continuously.

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광대역 불규칙 가진력을 받는 탄성진자계의 내부공진효과 (Influence of Internal Resonance on Responses of a Spring-Pendulum System under Broad Band Random Excitation)

  • 이원경;조덕상
    • 소음진동
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    • 제8권3호
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    • pp.399-407
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    • 1998
  • An investigation into the modal interaction of an autoparameteric systemunder broad-band random excitation is made. The specific system examined is a spring-pendulum system with internal resonance, which is known to be a good model for a variety of engineering systems, including ship motions with nonlinear coupling between pitching and rolling motions. By means of the Gaussian closure method the dynamic moment equations explaining the random responses of the system are reduced to a system of autonomous ordinanary differential equations of the first and second moments. In view of equilibrium solutions of this system and their stability we examine the system responses. The stabilizing effect of system damping is also examined.

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Dynamic responses of a riser under combined excitation of internal waves and background currents

  • Lou, Min;Yu, Chenglong
    • International Journal of Naval Architecture and Ocean Engineering
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    • 제6권3호
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    • pp.685-699
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    • 2014
  • In this study, the dynamic responses of a riser under the combined excitation of internal waves and background currents are studied. A modified Taylor-Goldstein equation is used to calculate the internal waves vertical structures when background currents exist. By imposing rigid-lid boundary condition, the equation is solved by Thompson-Haskell method. Based on the principle of virtual work, a nonlinear differential equation for riser motions is established combined with the modified Morison formula. Using Newmark-${\beta}$ method, the motion equation is solved in time domain. It is observed that the internal waves without currents exhibit dominated effect on dynamic response of a riser in the first two modes. With the effects of the background currents, the motion displacements of the riser will increase significantly in both cases that wave goes along and against the currents. This phenomenon is most obviously observed at the motions in the first mode.

중국 백화점의 물리적 환경에 따른 소비자의 내적반응이 점포충성도에 미치는 영향 (The Physical Environment Influence of Chinese Department Stores and Consumer's Internal Responses on Store Loyalty)

  • 장정정;전지현;이영선
    • 한국의류학회지
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    • 제37권2호
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    • pp.202-212
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    • 2013
  • Outstanding service quality is a crucial factor to increase customer revisits, to increase customer revisits, to create new customers through positive word-of-mouth marketing and increase profits; in conjunction, the physical environment of department stores have a firsthand impact on customer purchasing behavior. This study examines the physical environment dimensions of department stores in China and the causal relationship with the physical environment, service environment, internal responses and store loyalty. The subjects in this study were male and female adults who finished the shopping the Lotte and Wangfujing Department Store located in Beijing. All participants were over the age of 20 and a one-on-one survey was conducted to gather data from October to November 2011. Data from 424 respondents were analyzed: in addition, AMOS factor analysis and path analysis were used. The results were as follows. First, physical environment factors consist of exterior aesthetic attraction, convenience, cleanliness and an interior aesthetic attraction. Second, exterior aesthetic attraction, convenience and cleanliness affect the overall service environment perception. Third, the service environment exercised an influence on internal responses, and internal responses impacted store loyalty. Fourth, a comparative analysis was made over Korean and Chinese department stores in China to check the research model. In Wangfujing Department Store, exterior aesthetic attraction, cleanliness and convenience had a statistically significant impact on service environment perceptions. In Lotte Department Store, the perception of service environment was under the statistically significant influence of all physical factors (exterior aesthetic attraction, interior aesthetic attraction, convenience and cleanliness). The findings of this study are helpful for Korean Department stores that plan to make inroads into China to formulate efficient service environment strategies tailored to local consumer characteristics.