• 대한한방내과학회지
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• 제23권2호
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• pp.268-273
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• 2002

Anticonvulsant hypersensitivity syndrome includes fever, skin eruptions, lymphadenopathy, hematologic abnormality and hepatitis, but its mechanism remains unknown. Anticonvulsants including phenytoin, carbamazepine can cause hypersensitivity reaction. We treated a patient who had severe itching sensation and insomnia: he had undergone an operation for cerebral hemorrhage and was administered anti-convulsant agents to prevent convulsions. We administered the anti-convulsant, Dangkwieumja(Dangguiyinzi). After the treatment, clinical symptoms caused by hypersensitivity were improved.

• 대한한방내과학회지
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• 제26권4호
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• pp.776-784
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• 2005

Object : This study aims to assess the efficacy of Sopungsoongiwon(疏風順氣元) in constipated stroke patients and to find out the hepatotoxicity and nephrotoxicity of Sopungsoongiwon. Methods : Subjects were 111 patients who were admitted to tile hospital. The informations about the constipation and other factors were taken through medical records as follows : time until defecation, amount of Sopungsoongiwon until defecation, amount of stool, AST, ALT, BUN, Creatinine. We get the means and standard deviation from the various factors obtained from medical records. Results : 1. The mean time until defecation after taking Sopungsoongiwon was $20.919{\pm}17.885$ hours. 2. The dose of Sopungsoongiwon until defecation was $3.126{\pm}1.624$ packs. 3. The mean amount of stool was $135.360{\pm}63.288g$. 4. AST, ALT, BUN, Creatinine was maintained in normal range after taking sopungsoongiwon(p<0.0001).

• 대한한방내과학회지
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• 제32권2호
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• pp.243-258
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• 2011

Objectives : This study investigated the hypolipidemic and antioxidant effects of Curcuma radix using a rat model induced by poloxamer 407 injection. Methods : Serum lipid parameters and oxidative stress-associated biomarkers were determined. Additionally, hepatic cholesterol and triglyceride as well as lipid metabolism-associated gene expressions were observed in hepatic tissue. Results : 1. Curcuma radix ameliorated elevation of serum cholesterol, triglyceride, LDL-cholesterol, MDA, hepatic cholesterol level, and reduction of serum TAC, SOD, GSH, GSH-reductase level. 2. Curcuma radix augmented up-regulated ACAT gene expression. 3. Curcuma radix almost completely ameliorated down-regulated CYP-7A1 but up-regulated HMG-CoA gene expression. Conclusions : The hypolipidemic and antioxidant properties of Curcuma radix were evidenced. This study provides a scientific basis for the clinical application of Curcuma radix and development of hypolipidemics using this herb in the future.

• 대한한방내과학회지
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• 제21권5호
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• pp.845-850
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• 2000

Objective : This study was to investigate Soyang-Kyong negative acupuncture treatment of spasticity or rigidity in 41 patients. Methods : Let Sadok, Yangnungch' on, Kuho in side of spasticity or rigidity have negative acupuncture in the skin. Result and Conclusion : 1. Spasticity or rigidity was improved 33 case of 41 case by Soyang-Kyung negative acupuncture. 2. The spasticity was improved more than the rigidity. 3. Spasticity or rigidity of Basal Ganglia, Periventricular Whete Matter, Thalamrs is improved more than Spasticity or rigidity of M.C.A territory, Pons. 4. Spasticity or rigidity of Cb-mfaction is improved more than Spasticity or rigidity of Cb-hemorrloge.

• 대한한방내과학회지
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• 제30권4호
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• pp.657-673
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• 2009

This experiment was performed to determine the antihypertensive effect of Yangganhwadam-tang(YHT) on hypertension in spontaneously hypertensive rat. The results obtained were as follows : 1. YHT showed scavenging activity on DPPH free radical and SOD-like activity. 2. YHT significantly decreased heart weight. 3. YHT significantly decreased blood pressure and pulse. 4. YHT significantly decreased the level of plasma aldosterone. 5. YHT significantly decreased the level of norepinephrine. 6. YHT significantly decreased the levels of potassium and calcium. 7. YHT significantly decreased the level of BUN. 8. YHT decreased eosinophilic changes in the heart cells, and dilated renal arterioles stenosis. These results suggest that YHT might be effective in treatment and prevention of hypertension.

• 대한한방내과학회지
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• 제37권6호
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• pp.1051-1058
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• 2016

Objectives: This case study reports on a case of rhabdomyolysis that occurred after spinning exercise. Methods: A patient diagnosed with rhabdomyolysis received Korean medical treatment and Western medical treatment for 6 days. We observed the patient for 13 days. Clinical symptoms were evaluated with the Numerical Rating Scale (NRS) and laboratory tests that included Liver Function Test, Renal Function Test, creatinine phosphokinase (CPK), myoglobin, and urine. Results: The clinical symptoms improved after treatment. In this case, acute renal failure has not occurred. The Laboratory results, including AST, ALT, CPK, and LDH, improved. Conclusions: Rhabdomyolysis can be treated with Korean medical and Western medical cooperative treatment.

• 대한한방내과학회지
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• 제29권3호
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• pp.641-656
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• 2008

This study was done to investigate the effect of Gamichungyeoldodam-tang (GCDT) in DOCA-salt induced hypertensive rats. The results were obtained as follows : GCDT showed safety against cytotoxicity and toxicity in the liver and the kidney. GCDT showed an inhibitory effect on ACE. GCDT significantly decreased the heart rate and the blood pressure in DOCA-salt induced hypertensive rats. GCDT significantly decreased the levels of aldosterone in DOCA-salt induced hypertensive rats. GCDT significantly decreased the levels of dopamine, norepinephrine, and epinephrine in DOCA-salt induced hypertensive rats. GCDT significantly decreased the levels of chloride in DOCA-salt induced hypertensive rats. These results suggest that GCDT might be effective in treatment of hypertension.

• 대한한방내과학회지
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• 제29권3호
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• pp.684-702
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• 2008

This experiment was performed to determine the effect of Jibeakjihwanghwangami(JJHG) on hypertension in monocrotaline-induced hypertensive rats. The results obtained were as follows : 1. JJHG showed a safety in cytotoxicity and toxicity of liver. 2. JJHG showed scavenging activity on DPPH free radicals and SOD-like activity. 3. JJHG showed an inhibitory effect on ACE. 4. JJHG significantly decreased blood pressure and pulse in monocrotaline-induced hypertensive rats. 5. JJHG significantly decreased the levels of plasma aldosterone in monocrotaline-induced hypertensive rats. 6. JJHG significantly decreased the levels of potassium in monocrotaline-induced hypertensive rats. 7. JJHG significantly decreased the levels of uric acid. BUN, and creatinine in monocrotaline-induced hypertensive rats. These results suggest that JJHG might be effective in treatment and prevention of hypertension.

• 대한한방내과학회지
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• 제23권1호
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• pp.141-145
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• 2002

Diabetic Ketoacidosis(DKA), one of acute complications of diabetes mellitus(DM) occurs mostly in insulin dependent diabetes mellitus (IDDM) patients. Its clinical symptoms are hyperglycemia, ketonemia or ketonuria, metabolic acidosis, etc. The interaction of lack of insulin, excessive secretion of insulin antagonic hormone and dehydration cause body fluid loss and electrolyte, typical symptom of DKA as polyuria, polydipsia, nausea, vomiting, abdominal pain occur. As a result, prompt supply of fluid and insulin by intravenous injection should be conducted for treatment. It is still an emergent disorder whose mortality is still 10 to 15%, though is has decreased compared to the past. We treated a female patient who has DKA, had withdrawn insulin pump therapy. We report a case of DKA with a brief review of related literatures.

• 대한한방내과학회지
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• 제25권4호
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• pp.450-456
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• 2004

Guillain-Barre syndrome, or acute inflammatory polyneuritis, is a disorder in which the body's immune system attacks parts of the peripheral nervous system. The causes and mechanisms of this syndrome are unknown. Typically, Guillain-Barre syndrome can be diagnosed from the patient's symptoms and physical examination such as the rapid onset of weakness, paralysis and loss of reflexes. The analysis of CSF and electrical tests on nerve and muscle function can be performed to confirm the diagnosis. Most cases occur shortly after a viral infection. This is a clinical report about one patient suspected as having Guillain-Barre syndrome. The patient, a 62-year-old man had weakness in both legs after gastroduodenal disease. His weakness and general condition improved after Korean medical treatments, so this is reported as a potential treatment.