• Journal of Microbiology and Biotechnology
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• v.21 no.3
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• pp.243-251
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• 2011

The gene bolA was discovered in the 80's, but unraveling its function in the cell has proven to be a complex task. The BolA protein has pleiotropic effects over cell physiology, altering growth and morphology, inducing biofilm formation, and regulating the balance of several membrane proteins. Recently, BolA was shown to be a transcription factor by repressing the expression of the mreB gene. The present report shows that BolA is a transcriptional regulator of the dacA and dacC genes, thus regulating both DD-carboxypeptidases PBP5 and PBP6 and thereby demonstrating the versatility of BolA as a cellular regulator. In this work, we also demonstrate that reduction of cell growth and survival can be connected to the overexpression of the bolA gene in different E. coli backgrounds, particularly in the exponential growth phase. The most interesting finding is that overproduction of BolA affects bacterial growth differently depending on whether the cells were inoculated directly from a plate culture or from an overnight batch culture. This strengthens the idea that BolA can be engaged in the coordination of genes that adapt the cell physiology in order to enhance cell adaptation and survival under stress conditions.

• Journal of Korea Game Society
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• v.11 no.6
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• pp.13-22
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• 2011

In the digital media environment, the convergence is in the progress creating the new service and contents by users and developing the new needs of users by the service and contents as well. Social games are actualizing the new meaning of convergence. shows not only a new situation blurring the boundary of work and leisure, labor and playing and private and public sector, but how meaningful it is to make connection of social interactions and social assets a solid network. As the most popular social game text, reveals how the personal connections and personal networks constructs the social capital by making the ritual communication more interesting and flexible to the social gamers.

• Advances in aircraft and spacecraft science
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• v.3 no.2
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• pp.149-170
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• 2016

Multi-Disciplinary Optimization (MDO) is widely used to handle the advanced design in several engineering applications. Such applications are commonly simulation-based, in order to capture the physics of the phenomena under study. This framework demands fast optimization algorithms as well as trustworthy numerical analyses, and a synergic integration between the two is required to obtain an efficient design process. In order to meet these needs, an adaptive Computational Fluid Dynamics (CFD) solver and a fast optimization algorithm have been developed and combined by the authors. The CFD solver is based on a high-order discontinuous Galerkin discretization while the optimization algorithm is a high-performance version of the Artificial Bee Colony method. In this work, they are used to address a typical aero-mechanical problem encountered in turbomachinery design. Interesting achievements in the considered test case are illustrated, highlighting the potential applicability of the proposed approach to other engineering problems.

• Advances in Energy Research
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• v.5 no.3
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• pp.255-275
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• 2017

The advantages of using natural circulation (NC) as a cooling system, has prompted the worldwide development to investigate this phenomenon more than before. The interesting application of the NC in low power experimental facilities and research reactors, highlights the obligation of study in these laminar flows. The inherent oscillations of NC between hot source and cold sink in low Grashof numbers necessitates stability analysis of cooling flow with experimental or numerical schemes. For this type of analysis, numerical methods could be implemented to desired mass, momentum and energy equations as an efficient instrument for predicting the behavior of the flow field. In this work, using the explicit, implicit and Crank-Nicolson methods, the fluid flow parameters in a natural circulation experimental test loop are obtained and the sensitivity of solving approaches are discussed. In this way, at first, the steady state and transient results from explicit are obtained and compared with experimental data. The implicit and crank-Nicolson scheme is investigated in next steps and in subsequent this research is focused on the numerical aspects of instability prediction for these schemes. In the following, the assessment of the flow behavior with coarse and fine mesh sizes and time-steps has been reported and the numerical schemes convergence are compared. For more detail research, the natural circulation of fluid was modeled by ANSYS-CFX software and results for the experimental loop are shown. Finally, the stability map for rectangular closed loop was obtained with employing the Nyquist criterion.

• Journal of the Korean Institute of Gas
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• v.19 no.5
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• pp.104-111
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• 2015

The technology development of pipeline transportation of natural gas at artic and northern ice environments should be considered with unique characteristics of permafrost territory as a very interesting and challenging area. This work is to investigate bottleneck techniques and major impact factors through a literature search to figure out the core technology of the transport pipeline. Especially, theoretical approach themes could be determined to develop the technology flow assurance for permafrost regions through documentary survey on the considerations of thermo-fluid. Also, basic results through theoretical approaches could be achieved.

• Bulletin of the Korean Chemical Society
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• v.20 no.1
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• pp.35-41
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• 1999

Stability characteristics of hyperbolic reaction-diffusion equations with a reversible Brusselator model are investigated as an extension of the previous work. Intensive stability analysis is performed for three important parameters, Nrd, β and Dx, where Nrd is the reaction-diffusion number which is a measure of hyperbolicity, β is a measure of reversibility of autocatalytic reaction and Dx is a diffusion coefficient of intermediate X. Especially, the dependence on Nrd of stability exhibits some interesting features, such as hyperbolicity in the small Nrd region and parabolicity in the large Nrd region. The hyperbolic reaction-diffusion equations are solved numerically by a spectral method which is modified and adjusted to hyperbolic partial differential equations. The numerical method gives good accuracy and efficiency even in a stiff region in the case of small Nrd, and it can be extended to a two-dimensional system. Four types of solution, spatially homogeneous, spatially oscillatory, spatio-temporally oscillatory and chaotic can be obtained. Entropy productions for reaction are also calculated to get some crucial information related to the bifurcation of the system. At the bifurcation point, entropy production changes discontinuously and it shows that different structures of the system have different modes in the dissipative process required to maintain the structure of the system. But it appears that magnitude of entropy production in each structure give no important information related for states of system itself.

• Journal of English Language & Literature
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• v.60 no.2
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• pp.211-232
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• 2014

In late Victorian England, a "pervert" meant two things. One meaning designated a person who "turned" or converted from one sect of Christianity to another. In Wilde's time this referred specifically to converts from the established state Church of England to the transnational Roman Catholic Church. The other, newer meaning designated someone who turned from conventional heterosexual relations to a (as yet unnamed) homosexual orientation. In the context of the late Victorian empire, both were considered dangerous. The rising social and political influence of Roman Catholicism appeared threatening as a transnational Church invading a national one. For the Anglican Church of England, this crisis was played out what came to be known as the Oxford Movement, still influential during Wilde's time as a student there from 1874 to 1878. What is interesting in Wilde's life, as in his work, is the way he himself played with the dangerous transgressions inherent in being a "pervert." Sexually, he was converted to same-sex love while still a married man. In terms of religion, he remained fascinated with Catholicism, allegedly converting on his death-bed. But what is provocative is way that Wilde used one "perversion" to play into another: so that in such works as The Picture of Dorian Gray and Salome, his version of a kind of anti-Catholic Catholicism becomes a site of sexual desire, and sexual desire expression for that kind of spirituality, which, as unrequited longing, can ultimately n find no object adequate to its imagination.

• Korean Journal of Remote Sensing
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• v.21 no.1
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• pp.31-49
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• 2005

We first review some history of the Global Geodynamics Project (GGP), particularly in the progress of ground-satellite gravity comparisons. The GGP Satellite Project has involved the measurement of ground-based superconducting gravimeters (SGs) in Europe for several years and we make quantitative comparisons with the latest satellite GRACE data and hydrological models. The primary goal is to recover information about seasonal hydrology cycles, and we find a good correlation at the microgal level between the data and modeling. One interesting feature of the data is low soil moisture resulting from the European heat wave in 2003. An issue with the ground-based stations is the possibility of mass variations in the soil above a station, and particularly for underground stations these have to be modeled precisely. Based on this work with a regional array, we estimate the effectiveness of future SG arrays to measure co-seismic deformation and silent-slip events. Finally we consider gravity surveys in volcanic areas, and predict the accuracy in modeling subsurface density variations over time periods from months to years.

• Journal of Korean Classical Literature and Education
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• no.15
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• pp.31-66
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• 2008

In this study, I investigate the literary features and educational values of spoken travelogues by analyzing a travelogue about the Diamond Mountains by a farmer named Im, Chul-ho, a very interesting travelogue told for 70 minutes. It seems to have educational significance as a wonderful piece of literary work. The literary features of this tale can be summarized as follows. (1) It is truly 'literature of reality' which fully brings out literary appreciation; It evokes interest and emotional tension on the part of audience through vivid verbal embodiment of personal experiences; (2) It is a well constructed big story embedding small stories within it. The stories from many different travel points emerge into a whole unified story making it much richer and more attractive; and (3) It truly reflects the experiences and emotions of ordinary people. As such, it can be regarded as their spiritual property. In addition, spoken travelogues could be valuable as an object in literature education. It needs to be included in the literature curriculum and treated in the same way as written travelogues. With strengths as instructional materials, it could be effectively used to improve students' ability to express their daily experiences with literary sensibility and to make them better understand the lives of ordinary people in the past.

• Multiscale and Multiphysics Mechanics
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• v.1 no.1
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• pp.53-64
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• 2016

Amyloid fibrils have recently been considered as an interesting material, since they exhibit the excellent mechanical properties such as elastic modulus in the order of 10 GPa, which is larger than that of other protein materials. Despite recent findings of these excellent mechanical properties for amyloid fibrils, it has not been fully understood how these excellent mechanical properties are achieved. In this work, we have studied the nanomechanical deformation behaviors and properties of amyloid fibrils such as their elastic modulus as well as fracture strength, by using atomistic simulations, particularly steered molecular dynamics simulations. Our simulation results suggest the important role of the length of amyloid fibrils in their mechanical properties such that the fracture force of amyloid fibril is increased when the fibril length decreases. This length scale effect is attributed to the rupture mechanisms of hydrogen bonds that sustain the fibril structure. Moreover, we have investigated the effect of boundary condition on the nanomechanical deformation mechanisms of amyloid fibrils. It is found that the fracture force is critically affected by boundary condition. Our study highlights the crucial role of both fibril length and boundary condition in the nanomechanical properties of amyloid fibrils.