• 제목/요약/키워드: interdisciplinary studies

검색결과 851건 처리시간 0.027초

Mass Spectrometry in the Determination of Glycosylation Site and N-Glycan Structures of Human Placental Alkaline Phosphatase

  • Solakyildirim, Kemal;Li, Lingyun;Linhardt, Robert J.
    • Mass Spectrometry Letters
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    • 제9권3호
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    • pp.67-72
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    • 2018
  • Alkaline phosphatase (AP) is a membrane-bound glycoprotein that is widely distributed in the plasma membrane of cells of various organs and also found in many organisms from bacteria to humans. The complete amino acid sequence and three-dimensional structure of human placental alkaline phosphatase have been reported. Based on the literature data, AP consists of two presumptive glycosylation sites, at Asn-144 and Asn-271. However, it only contains a single occupied N-linked glycosylation site and no occupied O-linked glycosylation sites. Hydrophilic interaction chromatography (HILIC) has been primarily employed for the characterization of the glycan structures derived from glycoproteins. N-glycan structures from human placental alkaline phosphatase (PLAP) were investigated using HILIC-Orbitrap MS, and subsequent data processing and glycan assignment software. 16 structures including 10 sialylated N-glycans were identified from PLAP.

Enhanced and applicable algorithm for Big-Data by Combining Sparse Auto-Encoder and Load-Balancing, ProGReGA-KF

  • Kim, Hyunah;Kim, Chayoung
    • International Journal of Advanced Culture Technology
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    • 제9권1호
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    • pp.218-223
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    • 2021
  • Pervasive enhancement and required enforcement of the Internet of Things (IoTs) in a distributed massively multiplayer online architecture have effected in massive growth of Big-Data in terms of server over-load. There have been some previous works to overcome the overloading of server works. However, there are lack of considered methods, which is commonly applicable. Therefore, we propose a combing Sparse Auto-Encoder and Load-Balancing, which is ProGReGA for Big-Data of server loads. In the process of Sparse Auto-Encoder, when it comes to selection of the feature-pattern, the less relevant feature-pattern could be eliminated from Big-Data. In relation to Load-Balancing, the alleviated degradation of ProGReGA can take advantage of the less redundant feature-pattern. That means the most relevant of Big-Data representation can work. In the performance evaluation, we can find that the proposed method have become more approachable and stable.

여성학분야 인터넷 자원의 분류체계에 관한 연구 (A Study on the Classification Scheme of Internet Resource for Women's Studies)

  • 이란주;성기주;양정하
    • 한국도서관정보학회지
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    • 제32권3호
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    • pp.397-417
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    • 2001
  • 인터넷에서 제공되고 있는 검색엔진들은 모든 분야의 정보를 수집하여 분류하기 때문에 전문적인 검색을 원하는 이용자에게 유용한 정보원의 역할을 수행하지 못하고 있다. 따라서 특정분야의 효율적인 정보검색을 위한 체계적인 디렉토리의 구성과 배열로 이용자 편이를 도모해야 할 필요성이 있다. 따라서 본 연구에서는 인터넷 검색엔진에서 사용하고 있는 여성학 분야 및 전문데이터베이스 분류체계의 특징 및 문제점을 분석하여 여성학분야의 효율적인 분류체계에 관한 지침을 제안하고자 한다. 이를 위하여 인터넷 검색엔진 5개와 여성학 전문데이터베이스 3개를 선정하여 항목상세비교방법과 포괄성과 논리성 측면으로 비교하였으며 여성학분야의 성격인 간학문적(interdisciplinary), 다학문적(multidisciplinary) 성격을 반영한 분류체계의 지침을 제시하였다.

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텐저블 게임 콘솔: 입출력 일체화 개체를 이용한 물리적 엔터테인먼트 미디어에 대한 연구 (Tangible Game Console: Physical Entertainment Media Using I/O Coupling Units)

  • 한경훈;이우훈;윤완철
    • 한국HCI학회:학술대회논문집
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    • 한국HCI학회 2006년도 학술대회 1부
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    • pp.818-823
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    • 2006
  • 본 연구에서는 디지털 콘텐츠와 물리적 미디어가 유기적으로 결합할 수 있는 가능성을 모색하고자, 입출력 일체화 개체인 'I/O 셀(Cell)'과 그 집합체인 '텐저블 게임 콘솔(Tangible Game Console)'을 개발하였다. I/O 셀은 여러 종류의 센서와 액츄에이터가 하나의 물리적 노드 내에 통합되어 있는 개체로, 이 I/O 셀 다수를 집적하면 다양한 크기와 용도의 엔터테인먼트 미디어를 구성하는 것이 가능하다. 그 중 하나로 개발된 텐저블 게임 콘솔은 일종의 센서-액츄에이터 집합체로 셀들 사이의 연계를 통해 다양한 물리적 정보를 인식하고 표현할 수 있다. 텐저블 게임 콘솔은 기존 게임 콘텐츠의 주요한 표현 수단이었던 이미지와 텍스트 정보 대신에 물리적 정보를 통해 게임 콘텐츠를 구성하며, 조작대상과 조작수단이 일체화되어 있고, 또한 음악, 퍼즐, 액션 등 다양한 장르의 게임 콘텐츠가 적용 가능하다는 특징을 가지고 있다. 텐저블 게임 콘솔에서는 불, 바람, 물, 생명체 등의 물리적 현상을 형상/움직임/소리/빛 등을 통해 재현하며, 사용자는 이를 때리기/바람불기/흔들기/기울이기 등의 직접적인 조작을 통해 체험할 수 있다. 또한 물리적인 상호작용 과정이 일정한 게임 규칙을 가지고 구성되어 있어 지속성 있는 놀이 경험을 제공한다. 본 연구에서는 텐저블 게임 콘솔의 콘텐츠로 음악, 액션, 대전게임 등을 개발하였으며, 이 콘텐츠들의 놀이경험을 평가함으로써, 텐저블 게임 콘솔의 발전 가능성을 확인하였다.

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양방향 압전-유압 하이브리드 구동장치의 성능 시험 (Performance Evaluation of a Bidirectional Piezoelectric Hybrid Actuator)

  • 김소룡;하넉산;구남서;배병운;김태흔;고한서;이창섭
    • 한국군사과학기술학회지
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    • 제18권3호
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    • pp.213-219
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    • 2015
  • Piezoelectric-based hydraulic actuator is a hybrid device consisting of a hydraulic pump driven by piezoelectric stacks that is coupled to a conventional hydraulic cylinder via a set of fast-acting valves. Nowadays, such hybrid actuators are being researched and developed actively in many developed countries by requirement of high performance and compact flight system. In this research, a piezoelectric hybrid actuator has been designed and tested. To achieve bi-directional capabilities in the actuator, solenoid valves were used to control the direction of output fluid. The experimental testing of the actuator in uni-directional and bi-directional modes was performed to examine performance issues related to the solenoid valves. The results showed that the bi-directional performance was slightly lower than uni-directional performance due to air bubble developed in the valve system. A new design to solve the vacuum problem has been proposed to improve the performance of the hybrid actuator.

동태손상(動態損傷) 증후군(症候群)에 관한 연구 현황 고찰 (A Review Study on Movement System Impairment Syndromes)

  • 김정균;김현호;서재호;김동원;박영재;박영배
    • 대한한의학회지
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    • 제33권1호
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    • pp.79-89
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    • 2012
  • Objectives: Sahrmann, an American physical therapist, has developed a set of movement-related diagnoses on musculoskeletal pain syndromes (MPS). We reviewed articles for studies of objectification and quantification of Oriental medicine diagnosis system about MPS. Methods: The authors reviewed a total of 12 studies found on PubMed to obtain movement system impairment (MSI)-based classification categories. Results: The MSI system has been developed for objectification and quantification of physical therapists' MPS diagnoses. The MSI system of classification is based on the basic premise that loss of precise movement is the result of specific repetitive movements and positions in everyday life. The MSI system defines 8 categories in the shoulder region, 5 in the lumbar region, and 7 in the knee region. Treatment involves (1) educating the person about the specific directions of alignment and movement that appear to be contributing to the musculoskeletal problem, (2) modifying the direction - specific alignment and movement patterns during daily activities, and (3) exercises to address the impairments. Conclusions: The authors propose that MSI studies could help to advance an Oriental medical diagnosis system on musculoskeletal pain syndromes, because MSI shares similarity with Oriental medicine in terms of holism, views of constant motion, and mi-byung (subhealth) treatment.

Thermal Strain Measurement of Austin Stainless Steel (SS304) during a Heating-cooling Process

  • Ha, Ngoc San;Le, Vinh Tung;Goo, Nam Seo;Kim, Jae Young
    • International Journal of Aeronautical and Space Sciences
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    • 제18권2호
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    • pp.206-214
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    • 2017
  • In this study, measurement of thermophysical properties of materials at high temperatures was performed. This experiment employed a heater device to heat the material to a high temperature. The images of the specimen surface due to thermal load at various temperatures were recorded using charge-coupled device (CCD) cameras. Afterwards, the full-field thermal deformation of the specimen was determined using the digital image correlation (DIC) method. The capability and accuracy of the proposed technique are verified by two experiments: (1) thermal deformation and strain measurement of a stainless steel specimen that was heated to $590^{\circ}C$ and (2) thermal expansion and thermal contraction measurements of specimen in the process of heating and cooling. This research focused on two goals: first, obtaining the temperature dependence of the coefficient of thermal expansion, which can be used as data input for finite element simulation; and second, investigating the capability of the DIC method in measuring full-field thermal deformation and strain. The results of the measured coefficient of thermal expansion were close to the values available in the handbook. The measurement results were in good agreement with finite element method simulation results. The results reveal that DIC is an effective and accurate technique for measuring full-field high-temperature thermal strain in engineering fields such as aerospace engineering.

인문·지역연구에서의 정보시각화 활용 방안 연구 (A Study on Utilization Method of Information Visualization in the Humanities and Area Studies)

  • 강지훈;이동열;문상호
    • 예술인문사회 융합 멀티미디어 논문지
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    • 제5권5호
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    • pp.59-68
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    • 2015
  • 학제 간 융합은 학문의 발전을 위해 서로의 경계를 넘어 상이한 학문 간의 협업 연구를 통해 새롭고 의미 있는 지식을 창출할 수 있다. 최근에는 특히 인문학과 ICT가 융합된 형태인 디지털인문학이 주목받고 있다. 연구방법론 관점에서의 디지털인문학은 인문지식, 인문정보 등을 정보시스템을 활용하여 저장, 검색, 공유, 확산하고 연구를 위한 도구로 사용가능하며, 정보시스템 측면에서의 디지털인 문학은 다양한 시스템 형태로 구축 및 활용되고 있다. 그 중에서 다양한 정보나 지식을 일반적인 텍스트가 아닌 이미지나 멀티미디어, 기타 인터페이스를 활용해 시각화하여 나타내는 정보시각화와 연계된 디지털인문학 시스템에 관한 연구가 활발하다. 본 논문에서는 디지털인문학 기반의 정보시각화 유형 및 사례를 분석한 후에, 인문·지역연구에서의 정보시각화 활용 방안에 대하여 제안한다.

학제간 의사소통을 포함한 시뮬레이션 교육이 간호대학생의 의사소통 자신감, 의사소통 행위, 기술적 술기 수행에 미치는 효과 (Effects of Simulated Interdisciplinary Communication Training for Nursing Students on Self-confidence in Communication, Communication Behavior and Technical Skill Performance)

  • 남경아;김은정;고은정
    • 한국간호교육학회지
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    • 제23권4호
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    • pp.409-418
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    • 2017
  • Purpose: Ineffective communication between healthcare professionals leads to medical errors and puts patients at risk of harm. The aim of this study was to examine the effects of interdisciplinary communication training in simulated settings on self-confidence in communication, observed communication behavior, and technical skill performances of nursing students. Methods: A repeated measures design with one group was conducted. Data was collected from 92 nursing students through a self-administered questionnaire and an observed behavior checklist. Data analysis was performed using descriptive statistics, a paired t-test, the Wilcoxon signed rank test, the Friedmann test, a Repeated Measures ANOVA, and the Spearman correlation coefficient. Results: Self-confidence in communication, observed Identification-Situation-Background-Assessment-Recommendation-Read Back communication behavior, and technical skill performances of nursing students were significantly improved. In observed communication behavior, the performance of Assessment and Read Back communication significantly improved. However, communication of Background, Assessment, and Recommendation did not improve to a satisfactory level. Observed communication behavior was not correlated with the overall technical skill performance. Conclusion: These results indicate that interdisciplinary communication training in simulated settings was effective in improving nursing students' confidence and communication skills with physicians. Longitudinal studies with larger samples are recommended in order to verify the effects of interdisciplinary communication training on clinical outcomes as well as communication competence.