• Journal of the Korean Society of Tobacco Science
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• v.26 no.1
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• pp.64-72
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• 2004

On-going research has recently documented the certain tobacco specific nitrosamines (TSNAs) are formed during the curing process by an interaction of nitrogen oxides (NOx) contained in combustion gases and naturally occurring compounds in the tobacco leaves. Although the role of TSNAs in human health have been extensively investigated, little research has been conducted on the physical and chemical phenomena relating to their formation during curing. In this paper, we developed a mathematical model for describing NOx absorption into green (uncured) tobacco. We found considerable uptake of NOx by green tobacco with variations related to several factors. Specifically, tobacco from the lower stalk positions (bottom one third) absorbs more NOx gas per unit weight than tobacco from upper stalk positions. Additionally, the green tobacco packed with a density of 0.103 g/㎤ absorbs more NOx gas per unit weight than either 0.0443 g/㎤ or 0.0739 g/㎤. Further, the NOx absorption increases proportionally with temperature with the maximum absorption point around 4$0^{\circ}C$.

• Proceedings of the Korean Society of Medical Physics Conference
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• 2002.09a
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• pp.35-37
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• 2002

Conceptual design of the next generation PET with both high sensitivity and high spatial resolution has been performed. A detector unit using a depth encoding scheme was designed and constructed for trial. The unit consists of four Gd$_2$SiO$\sub$5/:Ce crystal blocks in a 2x2x4 array coupled to a position-sensitive photomultiplier tube having metal channel dynodes and 4x4 multi-anodes. Our proposed detector is a very reliable and simple solution suitable for volume PET devices since the proposed depth encoding scheme does not need additional photo-detectors.

• Journal of the Korea Society for Simulation
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• v.10 no.1
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• pp.35-50
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• 2001

Managing multi-echelon inventory systems has gained importance over the last decade mainly because integrated control of supply chains consisting of several processing and distribution stages has become feasible through modern information technology. Determination of optimal inventory policy for multi-echelon supply chain is made difficult by the complex interaction between the different levels. In this paper, we investigate performance of five inventory policies (fixed quantity order policy, fixed interval order policy, compromised order policy, lead time-fixed quantity order policy, and mixed order policy) in a multi-echelon supply chain by using a simulation model constructed with AweSim simulation language. The results of the simulation study show that the mixed order policy is the best among five inventory policies in the most test problems except the case when the stockout cost per unit is much higher than the inventory holding and transportation costs per unit.

• International Journal of Precision Engineering and Manufacturing
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• v.5 no.1
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• pp.5-12
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• 2004

A human-friendly interactive system that is based on the harmonious symbiotic coexistence of human and robots is explored. Based on this interactive technology paradigm, a robotic cane is proposed for blind or visually impaired travelers to navigate safely and quickly through obstacles and other hazards faced by blind pedestrians. The proposed robotic cane, "RoJi,” consists of a long handle with a button-operated interface and a sensor head unit that is attached at the distal end of the handle. A series of sensors, mounted on the sensor head unit, detect obstacles and steer the device around them. The user feels the steering command as a very noticeable physical force through the handle and is able to follow the path of the robotic cane easily and without any conscious effort. The issues discussed include methodologies for human-robot interactions, design issues of an interactive robotic cane, and hardware requirements for efficient human-robot interactions.ions.

• Archives of Plastic Surgery
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• v.39 no.3
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• pp.184-189
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• 2012

Keloid disease is a fibroproliferative dermal tumor with an unknown etiology that occurs after a skin injury in genetically susceptible individuals. Increased familial aggregation, a higher prevalence in certain races, parallelism in identical twins, and alteration in gene expression all favor a remarkable genetic contribution to keloid pathology. It seems that the environment triggers the disease in genetically susceptible individuals. Several genes have been implicated in the etiology of keloid disease, but no single gene mutation has thus far been found to be responsible. Therefore, a combination of methods such as association, gene-gene interaction, epigenetics, linkage, gene expression, and protein analysis should be applied to determine keloid etiology.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 2002.10a
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• pp.287-294
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• 2002

An automatic design method of steel frames using nonlinear analysis is developed. The geometric nonlinearity is considered by the use of stability functions. A direct search method is used as an automatic design technique. The unit value of each member is evaluated by using LRFD Interaction equation. The member with the largest unit value Is replaced one by one with an adjacent larger member selected in the database. The weight of the steel frame is taken as an objective function. Load-carrying capacities, deflections, interstory drifts, and ductility requirement are used as constraint functions. Case study of a three-dimensional two story frame are presented.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 2002.10a
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• pp.354-361
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• 2002

This paper propose section properties factor to generate stress history for fatigue analysis and safety inspection of steel bridge. A methodology is described for the computation of numerical stress histories in the steel truss bridge, caused by the vehicles using section properties factor. The global 3-D beam model of bridge is combined with the local shell model of selected details. Joint geometry is introduced by the local shell model. The global beam model takes the effects of joint rigidity and interaction of structural elements into account. Connection nodes in the global beam model correspond to the end cross-section centroids of the local shell model. Their displacements are interpreted as imposed deformations on the local shell model. The load cases fur the global model simulate the vertical unit force along the stringers. The load cases fer the local model are imposed unit deformations. Combining these, and applying vehicle loads, numerical stress histories are obtained. The method is illustrated by test load results of an existing bridge.

• International Journal of Naval Architecture and Ocean Engineering
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• v.6 no.3
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• pp.578-597
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• 2014

Understanding of 'spatial' pressure distribution is required to determine design loads on local structures, such as plating and framing. However, obtaining a practical 'spatial' pressure distribution is a hard task due to the sensitivity of the data acquisition frequency and resolution. High-resolution Pessure-Idicating Flm (PIF) was applied to obtain pressure distribution and pressure magnitude using stepped crushing method. Different types of PIF were stacked at each test to creating a pressure distribution plot at specific time steps. Two different concepts of plotting 'spatial' pressure-area curve was introduced and evaluated. Diverse unit pixel size was chosen to investigate the effect of the resolution in data analysis. Activated area was not significantly affected by unit pixel size; however, total force was highly sensitive.

• Journal of Sensor Science and Technology
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• v.20 no.2
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• pp.107-113
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• 2011

LSPR(Localized Surface Plasmon Resonance) sensor measures the refractive index change on the sensor surface. The detection of biological reaction with the unknown refractive index needs to be converted into the signal sensitivity for the refractive index change for comparison with other measurements. To find the signal sensitivity, the three steps of signal processing are proposed, which are signal modeling, signal calibration and signal normalization of LSPR sensor. The detected signal of biotin-streptavidin interaction has been converted into unit of [RU](Resonance Unit) using the proposed method. The converted signal directly can be compared with the other sensors including commercialized one.

• Interaction and multiscale mechanics
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• v.3 no.2
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• pp.111-121
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• 2010

Dynamic analysis of nano/micro bio-sensors based on a multiscale atomistic/continuum theory is introduced. We use a generalized atomistic finite element method (GAFEM) to analyze a bio-sensor which has $3{\times}N_a{\times}N_p$ degrees of freedom, where $N_p$ is the number of representative unit cells and $N_a$ is the number of atoms per unit cell. The stiffness matrix is derived from interatomic potential between pairs of atoms. This work contains two studies: (1) the resonance analysis of nano bio-sensors with different amount of target analyte and (2) the dependence of resonance frequency on finite element mesh. We also examine the Courant-Friedrichs-Lewy (CFL) condition based on the highest resonance frequency. The CFL condition is the criterion for the time step used in the dynamic analysis by GAFEM. Our studies can be utilized to predict the performance of micro/nano bio-sensors from atomistic perspective.