• KSBB Journal
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• 제16권6호
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• pp.538-546
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• 2001

효모의 세포주기 관련 유전자 발현 통합 데이터를 사용하여 본 연구실에서 개발한 유전자 발현 통합 분석프로그램을 사용하여, 클러스터링 알고리즘의 성능을 비교하고 데이터내에 존재하는 클러스터 개수를 추정하기 위해 FOM 분석을 적용하였으며, 이 분석방법을 통하여 K-means, SOM, Fuzzy c-means 클러스터링 방법의 성능을 서로 비교하였다. 클러스터 개수를 추정한 다음 3가지 클러스터링 방법에 대한 클러스터링 결과 비교, 클러스터의 기능할당 및 모티프 분석을 시도하였다. 본 논문에서 제시하는 분석 방법은 DNA chip 발현 데이터의 일반적인 분석방법을 유전자 발현 패턴의 유사성을 토대로 한 클러스터링 방법에 근간을 두고 있다. 본 논문에서는 클러스터링한 후 각 클러스터의 기능할당 및 모티프 분석에 대한 일반적인 분석방법을 제시하였으며, 본 연구실에서 개발한 유전자 발현분석 통합 프로그램이 효율적으로 사용될 수 있음을 보여주고 있다.

• KSBB Journal
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• 제16권4호
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• pp.381-388
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• 2001

DNA칩의 유전자 발현 데이터의 통합적 분석을 위하여 매트랩을 기반으로 한 통합분석 프로그램을 구축하였다. 이 프로그램은 유전자 발현 분석을 위해 일반적으로 많이 쓰는 방법인 Hierarchical clustering(HC), K-means, Self-organizing map(SOM), Principal component analysis(PCA)를 지원하며, 이외에 Fuzzy c-means방법과 최근에 발표된 Singular value decomposition(SVD) 분석 방법도 지원하고 있다. 통합분석프로그램의 성능을 알아보기 위하여 효모의 포자형성(sporulation)과 정의 유전자발현 데이터를 사용하였으며, 각 분석 방법에 따른 분석 결과를 제시하였으며, 이 프로그램이 유전자 발현데이타의 통합적인 분석을 위해 효과적으로 사용될 수 있음을 제시하였다.

• 한국태양에너지학회 논문집
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• 제28권1호
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• pp.1-8
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• 2008

The aim of this study is to develop the photovoltaic simulation program, called SimPV, which can Predict hourly based power generation of various PV modules and conduct an intensive economic analysis with Korean situation. To establish the reliability of the PV simulation results, we adopt the PV calculation algorithm of TRNSYS program of which verification has already well approved. Extensive database for hourly weather data of Korean 16 cities, engineering data for PV system and building load profiles are established. Case study on the 2.5kW roof integrated PV system and economic analysis are presented with the developed program.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 1999년도 가을 학술발표회 논문집
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• pp.378-386
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• 1999

The integrated system for the structural analysis of space frame is made up 4 modules ; pre-process module, structural analysis module, optimum member design module and post-process module. Re-process module of these 4 modules involves data input module and structure modeling module. This study is to develope an efficient modeling program as a basic for development of pre-process module. This modeling program generates geometric information of space frame and performs the input fie form for structure analysis only by input general data. User can mode1 space frame efficiently within shut time by using this program.

• 가정간호학회지
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• 제31권1호
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• pp.66-76
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• 2024

Purpose: This study aimed to develop and evaluate an integrated management program to enhance self-efficacy, compliance with sick-role behaviors, symptom management, and biomarker indication in hemodialysis patients. Methods: The integrated management program was developed through a systematic review of literature, analysis of relevant online data, and expert validation. It comprised 480 min of video-based education delivered eight times over four weeks, supplemented by weekly phone consultations and text message support from a nurse. To evaluate the program's effectiveness, it was administered to 44 patients with hemodialysis in a single group in a pre-post test experimental study. Changes in self-efficacy, sick-role behavior compliance, dialysis symptom index, and biomarkers were assessed. Results: The program yielded statistically significant improvements in self-efficacy (t=-7.13, p<.001), sick-role behavioral compliance (t=-7.35, p<.001), dialysis symptom index (t=4.32, p<.001), and blood urea nitrogen levels (t=2.55, p=.014) among the participants. Conclusion: The integrated management program is an effective intervention for improving hemodialysis patients' self-efficacy, compliance with sick-role behaviors, and experience of symptoms. Additionally, it is considered an intervention with high clinical applicability and efficiency through video reproducibility.

• Bulletin of the Korean Chemical Society
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• 제30권9호
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• pp.2061-2065
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• 2009

Two simple algorithm modifications are made to the THRASH data retrieval program with the aim of improving analysis speed for complex Fourier transform ion cyclotron resonance (FTICR) mass spectra. Instead of calculating the least-squares fit for every charge state in the backup charge state determination algorithm, only some charge states are pre-selected based on the plausibility values obtained from the FT/Patterson analysis. Second, a modification is made to skip figure-of-merit (FOM) calculations in the central m/z region between two neighboring peaks in isotopic cluster distributions, in which signal intensities are negligible. These combined modifications result in a significant improvement in the analysis speed, which reduces analysis time as much as 50% for ubiquitin (8.6 kDa, 76 amino acids) FTICR MS and MS/MS spectra at the reliability (RL) value = 0.90 and five pre-selected charge states with minimal decreases in data analysis quality (Table 3).

• KIEAE Journal
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• 제15권4호
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• pp.85-90
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• 2015

Purpose: In design and planning Building Integrated Photovoltaic(BIPV) system can reduce cost by replacing building facade as construction material such as roofs, outer walls and windows as well as generating electricity. BIPV system should be applied at the early stage of architectural design. However, it is hard to decide whether using BIPV system or not for architects and builders who are not professional at BIPV system because performance of system is considerably influenced by types of module, installation position, installation methods and so on. It is also hard for experts because commercialized analytical program of photovoltaic systems is too complicated to use and domestic meteorological data is limited to partial areas. Therefore, we need evaluation program of BIPV system which can easily but accurately interpret generating performance and evaluate validity of BIPV system at the early stage of architectural design even for inexpert. Method: In this study, we collected meteorological data of domestic major region and analyzed generation characteristic of BIPV system by using PVsyst(commercialized software) in accordance with regions, types of solar module, place and methods of installation and so on. Based on this data, we developed performance evaluation program of BIPV system named BIPV-Pro, through multiple regression analysis and evaluated its validity. Result: When comparing predictive value of annual average PR and annual electricity production of BIPV-Pro an that of PVsyst, each of root mean square error was 0.01897 and 123.9.

• Genomics & Informatics
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• 제4권1호
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• pp.40-44
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• 2006

Toxicogenomics combines transcriptome, proteome and metabolome profiling with conventional toxicology to investigate the interaction between biological molecules and toxicant or environmental stress in disease caution. Toxicogenomics faces the problems of comparison and integration across different sources of data. Cause of unusual characteristics of toxicogenomic data, researcher should be assisted by data analysis and annotation for getting meaningful information. There are already existing repositories which claim to stand for toxicogenomics database. However, those just contain limited abilities for toxicogenomic research. For supporting toxicologist who comes up against toxicogenomic data flood, now we propose novel toxicogenomics knowledgebase system, XPERANTO-TOX. XPERANTO-TOX is an integrated system for toxicogenomic data management and analysis. It is composed of three distinct but closely connected parts. Firstly, Data Storage System is for reposit many kinds of '-omics' data and conventional toxicology data. Secondly, Data Analysis System consists of analytical modules for integrated toxicogenomics data. At last, Data Annotation System is for giving extensive insight of data to researcher.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 1995년도 가을 학술발표회 논문집
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• pp.215-222
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• 1995

The objective of this paper is to develop a finite element structural analysis program using VB(Visual Basic) which has been recently getting popular as development tools of application program for Windows. VB provides several functions to develop an application program easily by supporting event-driven programming method and graphic object as control data type. This system is an integrated processor including preprocessor, solver and postprocessor. Automatic mesh generation is available at preprocess stage, and graphic presentation of deformation and stress is also represented at postprocess one.

• 한국안전학회지
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• 제27권5호
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• pp.219-223
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• 2012

For an off-site consequence analysis at nuclear power plant, MELCOR Accident Consequence Code System(MACCS) II code is widely used as a software tool. In this study, the algorithm of web-based off-site consequence analysis program(OSCAP) using the MACCS II code was developed for an Integrated Leak Rate Test (ILRT) interval extension and Level 3 probabilistic safety assessment(PSA), and verification and validation(V&V) of the program was performed. The main input data for the MACCS II code are meteorological, population distribution and source term information. However, it requires lots of time and efforts to generate the main input data for an off-site consequence analysis using the MACCS II code. For example, the meteorological data are collected from each nuclear power site in real time, but the formats of the raw data collected are different from each site. To reduce the efforts and time for risk assessments, the web-based OSCAP has an automatic processing module which converts the format of the raw data collected from each site to the input data format of the MACCS II code. The program also provides an automatic function of converting the latest population data from Statistics Korea, the National Statistical Office, to the population distribution input data format of the MACCS II code. For the source term data, the program includes the release fraction of each source term category resulting from modular accident analysis program(MAAP) code analysis and the core inventory data from ORIGEN. These analysis results of each plant in Korea are stored in a database module of the web-based OSCAP, so the user can select the defaulted source term data of each plant without handling source term input data.