• Title/Summary/Keyword: initiation point

Search Result 208, Processing Time 0.026 seconds

Neuronal Mechanisms that Regulate Vitellogenesis in the Fruit Fly (노랑초파리 난황형성과정 제어 신경 메커니즘)

  • Kim, Young-Joon;Zhang, Chen
    • Korean journal of applied entomology
    • /
    • v.61 no.1
    • /
    • pp.109-115
    • /
    • 2022
  • Vitellogenesis is the process by which yolk accumulates in developing oocytes. The initiation of vitellogenesis represents an important control point in oogenesis. When females of the model insect Drosophila melanogaster molt to become adults, their ovaries lack mature vitellogenic oocytes, only producing them after reproductive maturation. After maturation, vitellogenesis stops until a mating signal re-activates it. Juvenile hormone (JH) from the endocrine organ known as the corpora allata (CA) is the major insect gonadotropin that stimulates vitellogenesis, and the seminal protein sex peptide (SP) has long been implicated as a mating signal that stimulates JH biosynthesis. In this review, we discuss our new findings that explain how the nervous system gates JH biosynthesis and vitellogenesis associated with reproductive maturation and the SP-induced post-mating response. Mated females exhibit diurnal rhythmicity in oogenesis. A subset of brain circadian pacemaker neurons produce Allatostatin C (AstC) to generate a circadian oogenesis rhythm by indirectly regulating JH and vitellogenesis through the brain insulin-producing cells. We also discuss genetic evidence that supports this model and future research directions.

Prevalence of Postprandial Hypotension in the Elderly People with Hypertension according to Mealtimes (고혈압노인의 식사시간 별 식후저혈압 발생실태)

  • Son, Jung Tae;Lee, Eunjoo;Kim, Hyeonmi
    • 한국노년학
    • /
    • v.31 no.4
    • /
    • pp.969-983
    • /
    • 2011
  • The purposes of this study were to identify the degree of postprandial blood pressure reduction and the prevalence of postprandial hypotension by 3 different mealtimes of elderly people diagnosed with hypertension in nursing homes. After the informed and written consent, a total of 187 elderly people were recruited in the study. Systolic BP, diastolic BP were measured with ambulatory BP monitor every 15 minutes interval from 30 minutes before a meal until 120 minutes after each meal. The maximum SBP reduction was significantly bigger at breakfast than lunchtime or dinnertime. Among 187 elders, 137(73.4%) showed PPH at breakfast, 103(54.2%) at lunchtime, and 96(50.2%) at dinnertime. The most prevalent time point of PPH was 90 minutes after the initiation of a meal in all of 3 mealtimes. Among 8 measurement times, the prevalence of PPH was significantly higher in breakfast (3.0±2.7 times) than both lunchtime (2.1±2.5 times) and dinnertime (1.9±2.4 times). Although the occurrence of PPH by every mealtime should be taken into account in caring for the elderly, postprandial BP measurements need more attention after breakfast. Nurses should develop appropriate nursing interventions that can prevent postprandial blood pressure reduction in elderly people with hypertension.

Analysis of the Results of the 2022 Gyeonggi-do Korean Medicine Infertility Support Project (2022년도 경기도 한의약 난임지원사업 결과 분석 연구)

  • Hye-Sung Lee;Hyo-Jung Jung;Su-Ji Choi;Dong-Il Kim
    • The Journal of Korean Obstetrics and Gynecology
    • /
    • v.36 no.4
    • /
    • pp.78-95
    • /
    • 2023
  • Objectives: This study aims to analyze the results of the 2022 Gyeonggi-do Oriental Medicine Fertility Treatment Support Project, review the outcomes and satisfaction of Oriental Medicine fertility support initiatives, and propose progressive fertility treatment support strategies by comparing them with the results of the past three years. Methods: Total of 242 women and 205 spouses participated in the Korean Medicine fertility treatment support project, which encompassed herbal medicine, acupuncture, and counseling treatments over a 3-month period, followed by a 3-month post-treatment follow-up. Data pertaining to patients' general, demographic, and fertility-related characteristics were collected before treatment initiation. During treatment, information regarding the treatments administered by Korean medical doctors was recorded, along with post-treatment outcomes and satisfaction levels. Safety assessments included pre- and post-treatment blood tests and monitoring for adverse events. Results: Among the 242 female subjects, 209 successfully completed the treatment program. Of these, 35 (16.7%) achieved pregnancy, with 30 (15%) attaining pregnancy through herbal monotherapy. Out of the 35 pregnancies, 17 were maintained, while 10 resulted in miscarriage. Notably, 83.8% of patients expressed satisfaction with the treatment outcomes. An analysis spanning three years revealed a continuous increase in the average age of patients, surpassing 38 years in 2022, a critical point in fertility decline age. Additionally, there was a notable rise in the prevalence of patients with a history of gynecological issues, advanced spouse age, and semen abnormalities, which is assumed to have contributed to the decrease in the pregnancy success rate. Conclusions: This study compares the clinical results of the 2022 Gyeonggi-do Korean Medicine Fertility Treatment Support Project with those of the past three years. Based on these findings, recommendations are made to enhance the project, including stricter age criteria for patient selection, enhanced specialized treatment tools for medical doctors, and combining Korean Medicine treatment and medical assisted reproductive technologies, all aimed at increasing pregnancy success rates. These results provide a foundation for the development of fertility support projects and related policies.

Effects of a supportive workplace environment on the success rate for smoking cessation camp

  • Woojin Kim;A Ram Kim;Minsu Ock;Young-Jee Jeon;Heun Lee;Daehwan Kim;Minjun Kim;Cheolin Yoo
    • Annals of Occupational and Environmental Medicine
    • /
    • v.35
    • /
    • pp.48.1-48.13
    • /
    • 2023
  • Background: This study was conducted to identify the success rate for smoking cessation over time after participation in a therapeutic smoking cessation camp, and to identify how participant characteristics, including a supportive workplace environment for smoking cessation (SWESC), affect the success rate for smoking cessation. Methods: In all, 296 participants at smoking cessation camps in Ulsan between 2015 and 2020 were investigated. The success rates of smoking cessation after weeks 4, 6, 12, and 24 at camp were investigated. The participants were grouped as workers with an SWESC, and workers without an SWESC, and variables (age, education, household income, marital status, drinking, exercise, body mass index, morbidity, job, number of counseling sessions, cigarettes smoked per day and smoking initiation age) were investigated. Multiple logistic regression analysis was conducted at each time point. In addition, Cox regression analysis was performed to evaluate the variables affecting the success rate for smoking cessation over time. Results: The smoking cessation success rate of workers with an SWESC at week 24 (90.7%) was higher than that for workers without an SWESC (60.5%). Multiple logistic regression was performed to determine the relationship between each variable and the success rates for smoking cessation at week 6, 12, and 24. SWESC was confirmed as significant (p < 0.05) variables for increased success rate for smoking cessation at all 3 time points. After adjusting for all variables, the Cox proportional hazards survival analysis showed a hazard ratio of 6.17 for SWESC (p < 0.001,; 95% confidence interval: 3.08-12.38). Conclusions: At a professional treatment smoking cessation camp, participants with an SWESC showed a significantly higher success rate for smoking cessation. Supportive workplace environment for workers' health is expected to be an important factor for smoking cessation projects as well as other health promotion projects at workplace.

Identification and Measurement of Hospital-Related Fears in Hospitalized School-Aged Children (학령기 입원아동의 병원관련 공포에 관한 탐색연구)

  • 문영임
    • Journal of Korean Academy of Nursing
    • /
    • v.25 no.1
    • /
    • pp.61-79
    • /
    • 1995
  • When children are admitted to hospital, they have to adapt to new and unfamiliar stimuli. Children may respond with fear to stimuli such as pain or unfamiliar experiences. One goal of nursing is to help hospitalized children to adapt effectively to their hospital experience. Accordingly, nurses need to assess childrens' fears of their hospital experience to contribute to the planning of care to alleviate these fears. The problem addressed by this study was to identify and measure hospital-related fears(hereafter called HRF) in hospitalized school-aged children. The study was conceptualized with Roy's model. A descriptive qualitative approach was used first, followed by a quantitative approach. This study was conducted from November 30, 1989 to January 12, 1991. The sample consisted of 395 hospitalized school-aged children selected through an allocated sampling technique in nine general hospitals. The HRF questionnaire (three point likert scale ) was developed by a delphi technique. The data were analyzed by an SAS program. Factor analysis was used for the examination of component factors. Differences in the HRF related to demographic variables were examined by t-test, analysis of variance and the Scheffe test. The crude scores of the HRF scale were transformed into T- scores to calculate the standard scores. The results included the following : 1. Forty-four items were derived from 188 statements identifying the childrens' hospital-re-lated fears. These items clustered into 14 factors, fear of injections, operations, bodily harm others' pain, medical rounds, physical examinations, medical staff, disease process, blood and X-rays, drugs and cockroaches, tests, harsh discipline from parents or staff, being absent from school, and separation from family. The 14 factors was classified into four categories,'pain','the unfamiliar','the un-known' and 'separation'. 2. The reliability of the HRF instruments was .92(Cronbach's alpha). In the factor analysis, Cronbach's alpha coefficients for the 14 factors ranged from .84 to .86 and Cronbach's alpha coefficients for the four categories ranged from .70 to .84. Pearson correlation coefficient scores for relationships among the 14 factors ranged from ,11 to .50, and among the four categories, from ,44 to ,63, indicating their relative independence. 3. The total group HRF score ranged from 45 to 130 in a possible range of H to 132, with a mean of 74.51. The fears identified by the children were, in order, injections, harsh discipline by parents or staff, bodily harm, operations, medical staff, disease process, and medical rounds ; the least feared was others' pain. The fear item with the highest mean score was surgery and the lowest was examination by a doctor. HRF scores were higher for girls than for boys, and for grade 1 students than for grade 6 students. HRF scores were lower for children whose fathers were over 40 than for those whose fathers were in the 30 to 39 age group, and whose mothers were over 35 than for those whose mothers were in the 20 to 34 age group. HRF scores were lower when the mother rather than any other person stayed with the child. The expressed fear of pain, the unfamiliar, the un-known and of separation directs nurses' concern to the threat felt by hospitalized children to their concept of self. This study contributes to the assessment of fears of hospitalized children and of stimuli impinging on those fears. Accordingly, nursing practice will be directed to the alleviation of pain, pre-admission orientation to the hospital setting and routines, initiation of information about procedures and experiences and arrangments for mothers to stay with their children. Recommendations were made for further research in different settings and for development and testing of the instrument.

  • PDF

A Low Tillering Ideotype of Rice Plant for Increasing Grain Yield Potential (벼 수량성 증가를 위한 이상적인 소얼성 초형)

  • Kim, Je-kyu;Vergara, B.S.
    • KOREAN JOURNAL OF CROP SCIENCE
    • /
    • v.36 no.2
    • /
    • pp.134-142
    • /
    • 1991
  • Since IR8, the first high-yielding rice cultivar characterised by semidwarf and high-tillering, was released in 1966, rice yields during the last two decades have apparently reached a plateau and subsequent efforts to further improve yielding ability have not resulted in visible gains. At this point of time, a new ideotype of rice plant would be necessary to increase grain yield potential. This experiment was conducted to investigate the yield contribution of different tillers within a plant in relation to an ideo type of rice plant. A low-tillering, large panicled IR25588 was compared with a high-tillering, small panicled IR58. Based on spikelet number and grain weight per panicle, the top six panicles in both low- and high-tillering cultivarswere significantly bigger than those in the other panicles. The top six panicles were M, PI, P2, P3, P4 and S1P2 in both cultivars. Their tillers had 100% probability of occurring. The top six tillers were characterised by earlier initiation and heading, longer growth duration, greater leaf area. and heavier culm and total dry weight per tiller. The top six panicles, based on grain weight was mainly due to higher spikelet number per panicle with little differences in 1,000 grain weight and percent fertility. They had also a greater number of high -density grains. The top six panicles were significantly bigger than the rest of the panicles in both low- and high-tilliering types suggesting that a new rice ideotype having six or fewer potential tillers or panicles per paint with 200 to 250 spikelets per panicle (a low-tillering, paicle weight type) may help increase grain yield potential since they have been shown to be superior physio-morphologically to the rest of the tillers.

  • PDF

Simultaneous Removal of Cd & Cr(VI) by Fe-loaded Zeolite in Column System (Fe-loaded zeolite를 이용한 칼럼 실험에서의 Cd & Cr(VI) 동시제거 반응성 평가)

  • Lee Ah-Ra;Lee Seung-Hak;Park Jun-Boum
    • Journal of Soil and Groundwater Environment
    • /
    • v.11 no.1
    • /
    • pp.14-22
    • /
    • 2006
  • Laboratory column experiment for simultaneous removal of Cd and Cr(VI) were conducted using newly developed material of Fe-loaded zeolite having both reduction ability and sorption capacity. The solution containing Cd and Cr(VI) was injected into the column and the breakthrough curves (BTCs) for the contaminants were observed at the effluent port. Cd breakthrough was not initialized until Cr(VI) breakthrough was completed. Therefore it could be concluded that overall efficiency of Fe-loaded zeolite should be determined by the reactivity for Cr(VI). The relative concentration of Cr(VI) BTC increased to the unit value while initial breakthrough was delayed and the propagation of breakthrough was slowed. In order to quantitatively describe the shape of Cr(VI) BTC, new parameters of ${\alpha}\;and\;{\beta}$ designated to be shape parameters, were defined and applied in contaminant transport concentration. These parameters were employed to represent the degree of initial breakthrough delay and the degree of breakthrough propagation, respectively. As initial contaminant concentration increased, ${\alpha}$ decreased, which indicated the delay of BTC's initiation. And as initial contaminant flow rate increased, ${\beta}$ decreased, which represented the faster propagation of the BTC. From these results, Fe-loaded zeolite was found to be an effective reactive material for PRBs against heavy metals having different ionic forms in groundwater. And it could be expected that as groundwater flows faster, the propagation of breakthrough would be faster and as contaminant concentration is higher, the initial point of breakthrough would appear earlier.

The Space Use in the Initial Period of Namsan Park - Focus on the Newspaper Articles from 1883 to 1917 - (남산공원 태동기의 공간별 활용 유형 - 1883~1917년까지 신문기사를 중심으로 -)

  • Seo, Young-Ai;Son, Yong-Hoon
    • Journal of the Korean Institute of Traditional Landscape Architecture
    • /
    • v.31 no.1
    • /
    • pp.28-37
    • /
    • 2013
  • As a symbolic landscape of Seoul, Namsan has undergone not only physical changes but also changes in its human use and characteristics. At this point, research on Namsan, which holds diverse stories that have accumulated over a long period, as a cultural landscape is necessary. In particular, a concrete understanding of the characteristics of the mountain's use in the period of its initiation as a modern park is an important task in research on the history of urban parks. Consequently, the purpose of the present study lies in grasping the use of Namsan at the time of the establishment of Kyongsungbu Namsan Park Design Proposal in 1917 and examining the characteristics per space. The research process was based on the status of the park design plan. The primary source of information came from the analysis of historical newspaper articles. Additional materials including documents, old maps, photographs, postcard materials were also used. The period of the study was 1883 to 1917. This time was the initial period of Namsan Park soon after the opening up of Korea's ports to the world. The major spaces in which Namsan was used as a park encompassed Hanyang Park, Waeseongdae Park, Noin-jeong, Jangchung-dan, and remaining parts of Namsan in a natural state. When the main ways in which each space is used are examined based on the data analyzed, Namsan has been used for purposes including public events, accidents, religious worship, track and field days, field trips, and strolls. When the nature of each of the spaces is determined in terms of the characteristics of their use, these spaces were characterized as community parks, outdoor community spaces, indoor community spaces, sports arenas, and natural parks, among other things. The present study is significant in terms of research on the history of parks for confirming that Namsan in the initial period already served as a modern park for urban activities and grasping the specific urban activities that were engaged in on Namsan.

Factors Related to the Development of Myocardial Ischemia During Mechanical Ventilation (인공 호흡기 적용에 따른 심근 허혈의 발생에 관한 연구)

  • Kim, Tae-Hyung;Kim, You-Ho;Lim, Chae-Man;Kim, Won;Shim, Tae-Sun;Lee, Sang-Do;Kim, Woo-Sung;Kim, Dong-Soon;Kim, Won-Dong;Koh, Youn-Suck
    • Tuberculosis and Respiratory Diseases
    • /
    • v.46 no.5
    • /
    • pp.645-653
    • /
    • 1999
  • Introduction : Although myocardial ischemia tends to occur more frequently than can he documented in ventilated patients, it has not been well studied on the factors related to the occurrence of the ischemia. Methods : To investigate the related factors to ischemia development, a prospective study was done in 95 cases with consecutive 73 patients who had received mechanical ventilation(MV) in MICU. In addition to 24 h holter monitoring, echocardiogram, electrolytes, cardiac enzymes, hemodynamic, and gas exchange measurements were done within 24 h after initiation of MV in 69 cases. The measurements were repeated at weaning period in 26 cases. The ischemia was defined by the ST segment changes; up-sloping depression more than 1.5 mm or down-sloping or horizontal depression more than 1.0 mm from isoelectric baseline for 80 ms following J point. Results : Twelve patients(12.6% in 95 cases) developed ischemia in total. The incidence of ischemia development showed an increased tendency in the initial 24 hr after MV (15.9%) and in patients with left-sided heart failure found by echocardiogram (18.2%) compared with that of the weaning period (3.8%) and patients without heart failure (10.9%) (P=0.12, P=0.09, in each). There were no differences in APACHE III score, baseline ECG findings, electrolytes abnormalities, use of inotropics or bronchodilators, presence of sepsis or shock, mode of ventilation, and survival rate according to the development of ischemia. Maximal heart rates and mean arterial pressure also were not different between patients with ($137.2{\pm}30.9/min$, $82.5{\pm}15.9$ mm Hg) and without ischemia ($l29.5{\pm}29.7/min$, $83.8{\pm}17.6$ mm Hg). Conclusion : Although the incidence of myocardial ischemia was 12.6% in total, there were no clinically predictable factors to the development of ischemia during mechanical ventilation.

  • PDF

Storage condition that induce black heart of potato (Solanum tuberosom L.)

  • Jin, Yong-Ik;Chang, Dong-Chil;Cho, Ji-Hong;Yu, Dong-Lim;Nam, Jeong-Hwan;Yu, Hong-Seob;Koo, Bon-Choel;Choi, Jong-Kun;Lee, Soon-Ae
    • Proceedings of the Korean Society of Crop Science Conference
    • /
    • 2017.06a
    • /
    • pp.193-193
    • /
    • 2017
  • The black heart in potato is a physiological disorder that occurs when potatoes suffer from breathing problems. When storing potatoes at a low temperature around $0^{\circ}C$, there is a high possibility that the respiration rate of potato will rise and black heart will occur. Also, respiration can occur easily and briefly in a state where high temperature and ventilation is insufficient. Recently, as black heart has been occurred continuously and severely in South Korea, here we tried to identify the causes of black heart in potato and to develop the control strategy of this disorder. Firstly, we analyzed the influence on the black heart on the basis of preservation containers (breathable plastic box, burlap bag, paper box, sealed plastic box). After harvesting the potato which is cv. Superior, it preserved for 6 months under conditions of temperature $3.5^{\circ}C{\pm}0.2$ and humidity 85%, after then we surveyed the incidence of emergence rate, rate of weight loss and occurrence rate of black heart. Secondly, in order to investigate the time point of black heart initiation under the oxygen concentration condition of 1% or less, The potatoes were used for this experiment stored for 6 months in a aerated plastic box under conditions of temperature $3.5^{\circ}C{\pm}0.2$ and humidity 85% under sufficient oxygen condition. After stored for 6 month, those were stored at $15^{\circ}C$ and below 1% of oxygen for 25 days, and then the incidence of black heart was surveyed. Thirdly, to investigate the effects of the number of days after harvest on the occurrence of black heart, it was examined the occurrence of black heart stored on 40 days and 100 days after harvesting under sealed condition and vacuum condition. The temperature condition of potato storage was stored was at $4^{\circ}C$ and $25^{\circ}C$ in humidity 85%. As a result of investigating the occurrence of black heart depending on the storage containers, all of the potatoes stored in the sealed plastic box had been occurred black heart. However, black heart of the potatoes in the other treatments did not. Potato preserved under the condition of below 1% of oxygen was found to occur 32% black heart after 25 days of storage. The potatoes corresponding to the required number of days after harvesting were stored for 31 days and the black heart was examined on the occurred. As a result, the potatoes which were 40 days after the harvest did not have black heart under sealed condition and vacuum condition. But potatoes harvested 100 days after harvesting had a black heart incidence of 95.7% under sealed condition at $4^{\circ}C$. The potato placed in the vacuum condition and a sealed state at $25^{\circ}C$ was transformed into anaerobic respiration, the inner tissue of tuber collapsed. Therefore, it is considered that black heart is caused by the breathing trouble in the central part when the oxygen is almost consumed after the aerobic respiration which gradually consumes the oxygen. We conclude that the black heart occurred in the central part where exchange of oxygen and carbon dioxide is the slowest is sensitive to respiration disorder. It is thought that research to investigate black heart generation time according to storage conditions and post-harvest state of potatoes is further necessary.

  • PDF