• International Journal of Reliability and Applications
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• v.1 no.1
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• pp.27-38
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• 2000

In a recent paper Iskandar ＆ Sandoh (1999) studied an opportunity-based age replacement policy for a system which has a warranty period (0,S]. When the system fails at age x $\leq$ S a minimal repair is performed. If an opportunity occurs to the system at age x, S $\leq$ x $\leq$ T, we take the opportunity with probability p to preventively replace the system, while we conduct a corrective .replacement when its fails in (S,T). Finally, if its age reaches T, we perform a preventive replacement, Under this policy the design variable is T. For the case when opportunities occur according to a homogeneous Poisson process, the long-run average cost of this policy was formulated and studied analytically by Iskandar & Sandoh (1999). The same problem is here analysed by using a graphical technique based on scaled TTT-transforms. This technique gives, among other things, excellent possibilities for different types of sensitivity analysis. We also extend the discussion to the situation when we have to estimate T based on times to failure.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.9
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• pp.4213-4216
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• 2016

The incidence and prevalence, the second most common lymphoid malignancy after leukemia, are both increasing. The distribution of lymphoma varies among sexes, age groups, and sites. In Indonesia, information about the incidence of lymphoma and its characteristics are insufficient. Therefore, this study was performed to evaluate the incidence of lymphoma and features based on age group, sex, site, clinical diagnosis, and histopathological type in Indonesia. This study is an observational analytical study with a cross-sectional design aimed to evaluate the histopathological profile of lymphoma in Yogyakarta from 2010-2014. It was based on secondary data from Anatomic Pathology Department's medical records from several hospitals and laboratories. The result showed an increased incidence of lymphoma in Yogyakarta in 2010-2014 (p=0.039). Lymphoma mostly occurred in age range 45-64 years (p=0.004), dominated by male with ratio 1.6:1. DLBCL was found to be the most common histopathological type (44.4%). Sex, age, and clinical diagnosis demonstrated statistically significant correlations with the histopathological type (p<0.001). In conclusion, the incidence of lymphoma has significantly increased from 2010-2014. There are statistically significant correlations between gender, age, and clinical diagnosis with the histopathological type of lymphoma.

• Journal of Preventive Medicine and Public Health
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• v.53 no.3
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• pp.198-204
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• 2020

Objectives: This study aimed to analyze the mortality of heart disease (HD), ischemic heart disease (IHD), and cerebrovascular disease (CeVD) through an age-period-cohort (APC) analysis. Methods: We used data on mortality due to cardiovascular disease from 1995 to 2018 in Japan, as determined by Vital Statistics. Age groups from 0 years to 99 years were defined by 5-year increments, and cohorts were defined for each age group of each year with a 1-year shift. We used Bayesian APC analysis to decompose the changes in the diseases' mortality rates into age, period, and cohort effects. Results: The period effects for all diseases decreased during the analyzed periods for both men and women. The cohort effects for men increased substantially in cohorts born from around 1940 to the 1970s for all types of cardiovascular diseases. The cohort effects of HD decreased in the cohorts born in the 1970s or later for both men and women. Regarding IHD and CeVD, either a non-increase or decrease of cohort effects was confirmed for cohorts born in the 1970s or later for men, but the effects for women showed a continuously increasing trend in the cohorts born in the 1960s or later. Conclusions: The cohort effects for IHD and CeVD showed increasing trends in younger generations of women. This suggests that preventive approaches against cardiovascular diseases are needed, particularly for women.

• Korean Journal of Veterinary Service
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• v.23 no.3
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• pp.271-279
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• 2000

This study was carried out to provide the fundamental information for development of proper vaccination program against infectious bursal disease(IBD) to the local chicken farms. The antigen detection was peformed from 8 samples of bursa of Fabricius with agar gel precipitation(AGP) and indirect immunofluorescent assay(IFA), And also, the antibodies in serum samples were detected by the various serological methods such as commercial ELISA assay, AGP and virus neutralization(VN) test. 1. The antigen detection rates were 25% for AGP which is 2 out of 8 farms and 10 out of 40 bursas, and 25% which Is 2 out of 8 farms and 20% 8 out of 40 bursas for IFA, respectively. 2. The mean titer of maternal antibody (>3,000) existed until 10 days of the age with ELISA-GMT. 3. The antibody positive rates which are over 80% showed until 5 days of the age with ELISA and at 10 days of the age with AGP except one, but none of them showed from 1 day of the age. This report came to conclusions that both the protective maternal antibody titers and the antigen positive rates were significant until at the 10 days of the age.

• Journal of the Korean Home Economics Association
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• v.41 no.12
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• pp.13-26
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• 2003

This study was designed (1) to examine adolescents' body cathexis, ideal body image, clothing behavior, and clothing purchasing behavior, and (2) to identify gender and age differences. Descriptive statistics, Chi-Square ($\chi^2$) analysis, Analysis of Variance (ANOVA), and Duncan-Test were employed to analyze the data collected from the convenience sample of 729 middle- and high-school students in Gyeongnam, Korea. Adolescents tended to be dissatisfied with their body, while female high school students' dissatisfactory degrees were higher The ideal body image was thinner than normal, and neither gender nor age differences were observed. Adolescents showed higher dependences compared to other clothing behaviors including conformity, fashion, popularity, brand, and exhibition, and gender and age differences were observed. Fit/comfort and clothing displayed in store were most important evaluative criterion and information search method. Adolescents tended to prefer shopping in department store with friends or parents in less than 3 hours. Gender and age differences were observed in those clothing purchasing behavior. Marketing strategies generated from the results of this study were suggested.

• Nuclear Engineering and Technology
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• v.50 no.6
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• pp.929-936
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• 2018

A basic characterization of uranium samples was performed using gamma- and X-ray spectroscopy. The studied uranium samples were eight types of certified reference materials with $^{235}U$ enrichments in the range of 1-97%, and the measurements were performed over 24 h using a high-resolution and high-purity planar germanium detector. A general peak analysis of the spectrum and the $XK_{\alpha}$ region of the uranium spectra was carried out by using HyperGam and HyperGam-U, respectively. The standard reference sources were used to calibrate the spectroscopy system. To obtain the absolute detection efficiency, an effective solid angle code, EXVol, was run for each sample. Hence, the peak activities and isotopic activities were determined, and then, the total U content and $^{234}U$, $^{235}U$, and $^{238}U$ isotopic contents were determined and compared with those of the certified reference values. A new method to determine the model age based on the ratio of the activities of $^{223}Ra$ and $^{235}U$ in the sample was studied, and the model age was compared with the known true age. In summary, the present study developed a method for basic characterization of uranium samples by nondestructive gamma-ray spectrometry in 24 h and to obtain information on the sample age.

• Journal of Information Technology Services
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• v.6 no.1
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• pp.83-99
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• 2007

The purpose of this research is to identify the determinants of loyalty in online games. This study developed a research model to analyze the factors explaining the loyalty level from gamers, employing social identification, flow, and positive anticipated emotion as major research variables, and collected 1308 survey responses from gamers. Within the context of arguing that the exploration of age range issues with respect to online games is important, this research also examines the age differences in path coefficients. To this end, the structural model was tested with the data from entire data sample (i.e., the age of 10s, 20s, and 30s pooled together) and each of the subsamples (i.e., teens taken separately, twenties taken separately, and thirties taken separately). Properties of the causal paths, including standardized path coefficients, the significance of difference, in the hypothesized model, are also presented, so that we can investigate the relative influences of different dominants, demonstrating how teens, twenties, and thirties differ in their decision-making processes regarding the flow, social identification and loyalty from online games.

• The Journal of Industrial Distribution & Business
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• v.5 no.4
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• pp.5-11
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• 2014

Purpose - This paper examines Kazakh women's spending patterns and buying behavior. Research design, data, and methodology - After thoroughly reviewing the related literature on consumer behavior in general, and female consumer behavior in particular, both questionnaires and in-depth personal interviews were used to collect data from 400 Kazakh women consumers equally chosen from the age groups 20-30, 30-40, 40-50, and above 50. Results - A stratified and convenient sample was employed, and the selected five hypotheses were proved using the Karl Pearson Coefficient of Correlation. Related to spending patterns, 40 and 35 percent of the 20-30 and 30-40 age groups, respectively, of Kazakh women spend their incomes on personal items, as against 30 percent from both the 40-50 and 50 and above age groups. Twenty-five and 35 percent of the 40-50 and 50 and above age group, respectively, take decisions based on product quality, whereas this percentage is at its mite in the below 40 age group. Conclusions - The buying behavior of Kazakh women consumers is revealed; the results proffer useful background information to formulate marketing strategies.

• The Journal of Industrial Distribution & Business
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• v.12 no.8
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• pp.33-39
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• 2021

Purpose: The influence of age on time preference is not identified in the usual cross-sectional analysis. This study aims to test whether age affects time preference after controlling for the effects of individual heterogeneity including cohort effects. Research design, data and methodology: Drawing on a nationally representative panel dataset of Indonesians, we estimate the effects of age on time preference after controlling for unobserved individual heterogeneity as well as potential cohort effects. We measure time preference exploiting information on two sets of multiple price lists: one for a one-year delay, and the other for a five-year delay. Results: When we controlled for time-invariant individual characteristics, including birth cohort effects in a fixed effects model, the older men and women were more patient in a linear fashion, particularly when the delay was longer. To highlight the importance of controlling for individual fixed effects, we repeated the specification without controlling for individual fixed effects in OLS or censored maximum likelihood regression; we found no relation between age and impatience in men or women and for a one or five-year delay. Conclusions: The older men and women are more patient, and time preferences are correlated with unobserved individual heterogeneity.

• BMB Reports
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• v.52 no.1
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• pp.47-55
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• 2019

Cellular senescence (CS) is one of hallmarks of aging and accumulation of senescent cells (SCs) with age contributes to tissue or organismal aging, as well as the pathophysiologies of diverse age-related diseases (ARDs). Genetic ablation of SCs in tissues lengthened health span and reduced the risk of age-related pathologies in a mouse model, suggesting a direct link between SCs, longevity, and ARDs. Therefore, senotherapeutics, medicines targeting SCs, might be an emerging strategy for the extension of health span, and prevention or treatment of ARDs. Senotherapeutics are classified as senolytics which kills SCs selectively; senomorphics which modulate functions and morphology of SCs to those of young cells, or delays the progression of young cells to SCs in tissues; and immune-system mediators of the clearance of SCs. Some senolytics and senomorphics have been proven to markedly prevent or treat ARDs in animal models. This review will present the current status of the development of senotherapeutics, in relation to aging itself and ARDs. Finally, future directions and opportunities for senotherapeutics use will discussed. This knowledge will provide information that can be used to develop novel senotherapeutics for health span and ARDs.