• 식품과학과 산업
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• 제45권4호
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• pp.16-20
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• 2012

Although the technology of breadmaking simply goes through the process of mixing, fermentation, and baking, it is very hard to make a same product every day. The reason is that baking science begins with the very first process of breadmaking which is mixing, and every steps and working environments are so closely connected. The baking science has developed in short time since the theory of fermentation has released. If you check the development of baking technology synthetically, it is consisted of the discovery of nutritional and functional ingredients, the optimization process of new machines, and the maintenance of the quality as fulfilling social demands. Because the baking business is making and selling the product, baking itself is a business, and it has the form that manufacturing and service business coexist. In today's current domestic bakery market, the supply exceeds the demand. Moreover, the concept of bakery itself has been changing from the fixed image of bakery which is selling the bread to the differentiated bakery with others. As we look at the general bakery's trends, it is focused on going back to the basic or traditions, going to the functional, and working with automations. To conclude, the baking has a long history, but it actually has the short history in the technological development. Baking business can be viewed as the simple business, but many factors are related to the business. It has a few basic kinds of products in baking, but it has diverse kinds of products with the base of infinite creativity. Even though it is physically a hard working business, it is also a business that can face with fun. For managing a bakery, finally, the differentiated strategy with other bakery that maximizes the customers' value is needed.

• Bulletin of the Korean Chemical Society
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• 제23권2호
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• pp.229-240
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• 2002

Quantum mechanical calculation is performed for the $O(^1D)$ + HCl ${\rightarrow}$OH + Cl reaction using Reactive Infinite Order Sudden Approximation. Shifting approximation is also employed for the l ${\neq}$ 0 partial wave contributions. Various dynamical quantities are calculated and compared with available experimental results and quasiclassical trajectory results. Vibrational distributions agree well with experimental results i.e. product states mostly populated at $v_f$ = 3, 4. Our results also show small peak at $v_f$ = 0, which indicates bimodal vibrational distribution. The results show two significant broad peaks in ${\gamma}_i$ dependence of the cross section, one is at ${\gamma}_i$ = $15^{\circ}-35^{\circ}$ and the another is at ${\gamma}_i$= $55^{\circ}-75^{\circ}$ which can be explained as steric effects. At smaller gi, the distribution is peaked only at higher state ($v_f$ = 3, 4) while at the larger gi, both lower state ($v_f$ = 0) and higher state ($v_f$ = 3, 4) are significantly populated. Such two competing contributions (smaller and larger ${\gamma}_i$) result in the bimodal distribution. From these points we suggest two mechanisms underlying in current reaction system: one is that reaction occurs in a direct way, while the another is that reaction occurs in a indirect way.

• Journal of Information Technology Applications and Management
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• 제23권4호
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• pp.117-125
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• 2016

Software reliability in the software development process is an important issue. In infinite failure non-homogeneous Poisson process software reliability models, the failure occurrence rates per fault. can be presented constant, monotonic increasing or monotonic decreasing pattern. In this paper, the reliability software cost model considering decreasing intensity function was studied in the software product testing process. The decreasing intensity function that can be widely used in the field of reliability using power law process, log-linear processes and Musal-Okumoto process were studied and the parameter estimation method was used for maximum likelihood estimation. In this paper, from the software model analysis, we was compared by applying a software failure interval failure data considering the decreasing intensity function The decreasing intensity function model is also efficient in terms of reliability in the arena of the conservative model can be used as an alternating model can be established. From this paper, the software developers have to consider life distribution by preceding information of the software to classify failure modes which can be gifted to support.

• 한국의류산업학회지
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• 제9권3호
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• pp.262-269
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• 2007

Traces of ancestors in the era without letters can be found in their legacies and remains such as stone implement, earthenware, dwelling sites, etc. Petroglyph among them reflects their life and spirits as like an epic so that we can be with them through petroglyph. petroglyph is a common culture of mankind, which has been found in various places over the world. The infinite value of traditional culture has a great impact as much as it is unnecessary to more discuss about it. When a culture of a country is reproduced as a world-class product, the country can have visible profits as well as positive effects on diverse fields. The Pangudae petroglyph in Ulsan, consistion of fishery and huntihg religiong, is one of the greatest cultural legacies of the local own uniqueness, and a source and thesaurus of design development. Despite limited tools and unskilled tact, the Pangudae petroglyph Carving shows a strong vital power, which does not change by time, of a whale or a man with various methods such as line and face carving, embossed carving, etc. under a desperate and unconditional purpose, the survival. Thus, the study tries to suggest scarf designs that applies such beauty in fashion design by using the formative beauty caused by natural abrasion through the time, and the feel of lines and stony material.

• 디자인학연구
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• 제19권2호
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• pp.183-194
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• 2006

본 논문은 인식론적인 측면에서 디지털 인터페이스의 새로운 가능성을 확인하는데 그 목적이 있다. 우선 디지털 인터페이스의 역사를 개관함으로써 현재의 인터페이스가 우연적 계기들의 산물임을 밝히고 있다. 그것이 필연적인 결과가 아니라는 사실은 새로운 디지털 인터페이스가 무한히 존재할 수 있음을 암묵적으로 증언한다. 현실의 제한된 인터페이스는 디지털 기술과 디지털 미디어에 대한 제한적 이해로부터 파생하였다. '블랙박스'라는 은유를 통한 이해가 바로 그것이다. 본 논문은 디지털을 일종의 빛으로 보는 사유를 통해 이러한 이해를 극복하고 있다. 빛으로서의 디지털과 디지털 미디어라는 새로운 인식론은 인터페이스 디자인 활동이 차이를 긍정하고 생성하는 창조적 활동으로 나아가야 한다는 윤리학으로 발전한다.

• Food Science and Biotechnology
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• 제15권4호
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• pp.572-577
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• 2006

The physiochemical interactions of 1-methylcyclopropene (1-MCP) and adsorbing agents can be described using a very powerful tool, inverse gas chromatography (IGC). Sorption behavior of 1-MCP on various adsorbing agents was assessed using the profile peaks of 1-MCP at an infinite dilution concentration using the IGC technique. Chromatogram peaks of 1-MCP adsorption were not observed for the adsorbing agent activated carbon. The forms of sorption isotherms followed Henry's law, and behaved according to the binding site theory. Specific retention volume and distribution coefficients for 1-MCP on the adsorbing agents were determined at 50, 60, 70, and $80^{\circ}C$, respectively. Silica gel had a much higher number of binding sites for 1-MCP compared to Tenax-TA and activated clay agents. Meanwhile, activated carbon proved to be a very strong binding agent for 1-MCP based on 1-MCP efficiency experiments on the selected adsorbing agents. However, as a proper means of delivering 1-MCP molecules to fresh food products, activated carbon is not fit for the binding and release of 1-MCP gas under dry or high humidity conditions because activated carbon has a strong affinity for 1-MCP, even when treated with distilled water.

• 디지털산업정보학회논문지
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• 제10권4호
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• pp.19-27
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• 2014

Software reliability in the software development process is an important issue. Software process improvement helps in finishing with reliable software product. Infinite failure NHPP software reliability models presented in the literature exhibit either constant, monotonic increasing or monotonic decreasing failure occurrence rates per fault. In this paper, proposes the reliability model with log type mean value function (Musa-Okumoto and log power model), which made out efficiency application for software reliability. Algorithm to estimate the parameters used to maximum likelihood estimator and bisection method, model selection based on mean square error (MSE) and coefficient of determination($R^2$), for the sake of efficient model, was employed. Analysis of failure using real data set for the sake of proposing log type mean value function was employed. This analysis of failure data compared with log type mean value function. In order to insurance for the reliability of data, Laplace trend test was employed. In this study, the log type model is also efficient in terms of reliability because it (the coefficient of determination is 70% or more) in the field of the conventional model can be used as an alternative could be confirmed. From this paper, software developers have to consider the growth model by prior knowledge of the software to identify failure modes which can be able to help.

• Journal of Pharmaceutical Investigation
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• 제23권1호
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• pp.41-49
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• 1993

The bioequivalence of two omeprazole enteric-coated products was evaluated in 16 normal male volunteers (age 26-32 yr, body weight 57-75 kg) following single oral administration. Test product was enteric-coated KD-182 tablet (Chong Kun Dang Corp., Korea) and reference product was $Rosec^{\circledR}$ capsule containing enteric-coated pellets of omeprazole (Yuhan Corp., Korea). Both products contain 20 mg of omeprazole. One tablet or capsule of the test or the reference product was administered to the volunteers, respectively, by randomized two period cross-over study ($2\;{\times}\;2$ Latin square method). Average drug concetrations at each sampling time and pharmacokinetic parameters calculated were not significantly different between two products(p>0.05); the area under the concentrationtime curve to last sampling time (8 hr) $(AUC_{0-8hr})$ $(1946.5{\pm}675.3\;vs\;2018.3{\pm}761.6\;ng{\cdot}hr/ml)$, AUC from time zero to infinite $(AUC_{o-\infty})$ $(2288.6{\pm}1212.8\;vs\;2264.9{\pm}1001.3\;ng{\cdot}hr/ml)$, maximum plasma concentration $(C_{max})$ $(772.5{\pm}283.3\;vs\;925.8{\pm}187.7\;ng/ml)$, time to maximum plasma concentration $(T_{max})$ $(2.38{\pm}1.06\;vs\;2.34{\pm}1.09\;hr)$, apparent elimination rate constant $(k_{\ell})$ $(0.5339{\pm}0.2687\;vs\;0.5769 {\pm}0.2184\;hr^{-I})$, apparent absorption rate constant $(k_a)$ $(1.1536{\pm}0.5278\;vs\;0.9739{\pm}0.9507 hr^{-1})$ and mean residence time (MRT) $(3.13{\pm}0.73\;vs \;3.41{\pm}1.04\;hr)$. The differences of mean $(AUC_{0-8hr})$, $C_{max}$, $T_{max}$ and MRT between the two products (3.69, 19.83, 1.32 and 8.99%, respectively) were less than 20%. The power $(1-{\beta})$ and treatment difference $(\triangle)$ for $AUC_{o-8hr}$ $C_{max}$ and MRT were more than 0.8 and less than 0.2, respectively. Although the power for $T_{max}$ was under 0.8, $T_{max}$ of the two products was not significantly different each other(p>0.05). These results suggest that the bioavailability of KD-182 tablet is not significantly different from that of $Rosec^{\circledR}$ capsule. Therefore, two products are bioequivalent based on the current results.

• Biomolecules & Therapeutics
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• 제6권2호
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• pp.219-224
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• 1998

The bioequivalence of two clarithromvcin products was evaluated with 16 normal male volunteers (age 23-28 yr, body weight 57.5-75.517g) following single oral dose. Test product was ReYon Clarithromycin tablets (ReYon Pharm. Corp., Korea) and reference product was Klarici $d_{R}$ tablets (Abbott Korea). Both products contain 250 mg of clarithromucin. One tablet of the test or the reference product was administered to the volunteers, respectively, by randomized two period cross-over study (2$\times$2 Latin square method). The determination of clarithromycin was accomplished using a modified agar well diffusion bioassay. As a result of the assay validation, the quantification of clarithromycin in human serum by this technique was possible down to 0.03$\mu$g/ml using 100$\mu$l of serum. The coefficient of variation (C.V.) was less than 10%. Average drug concentrations at each sampling time and pharmacokinetic parameters calculated were not significantly different between two products P>0.05); the area under the curve to last sampling time (24 hr) (AU $Co_{24hr}$ (8.10$\pm$ 1.26 vs 8.22$\pm$ 1.627g . hr/ml), AUC from time zero to infinite (AU $Co_{\infty}$) (8.61 $\pm$ 1.28 vs 8.84$\pm$ 1.71 $\mu$g . hr/ml), maximum plasma concentration ( $C_{msx}$) (0.87$\pm$0.22 vs 0.88$\pm$0.19 $\mu$g/ml) and time to maximum plasma concentration ( $T_{max}$) (2.69 $\pm$0.48 vs 2.56$\pm$ 0.51 hr). The differences of mean AU $Co_{24h}$, $C_{msx}$ and $T_{msx}$ between the two products (1.44, 1.39, and 4.65%, respectively) were less than 20%. The power (1-$\beta$) and treatment difference ($\Delta$) for AU $Co_{24hr}$, and $C_{max}$ were more than 0.8 and less than 0.2, respectivly. Although the power for $T_{max}$ was under 0.8, $T_{max}$. of the two products was not significantly different each other (p>0.05). These results suggest that the bioavailability of ReYon Clarithromycin tablets is not significantly different from that of Klarici $d_{R}$ tablets. Therefore, two products are bioequivalent based on the current results. results.sults.sults.s.s.s.s.s.s.s.

• 응용통계연구
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• 제33권4호
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• pp.365-377
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• 2020

선형모형에서 두개 이상의 설명변수들 사이에 존재하는 다중공선성 문제를 변수들 간에 내재되어 있는 공통의 구조인 인자를 구성하고, 인자들을 회귀변수로 사용하여 해결하는 인자회귀모형에 대하여 논의한다. 무한개로 가정 가능한 내재된 인자 중 유의미한 인자적재행렬을 구성하기 위하여 벌점모수의 값이 큰 LASSO 사전분포를 적용하는 베이지안 추정법을 사용한다. 결정된 인자적재행렬과 다른 모수들의 추정값을 각 설명변수의 선형모수로 역변환 하여, 새로운 관측값에 대한 예측 모형으로도 사용한다. 제안한 방법을 제품 서비스 관리 자료에 적용하여 정해진 인자의 개수에 대한 인자가 일반적인 공통인자회귀모형과 동일한 결과를 나타냄을 확인하였고, 일반적인 공통인자회귀모형과 비교를 위해 계산한 평균 제곱 오차값이 더 작다는 것을 알 수 있었다.