• Journal of the Korean Geotechnical Society
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• v.29 no.9
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• pp.5-15
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• 2013

In this paper, the unsaturated slope stability analysis considering suction stress (Lu and Godt, 2008) was introduced and the results applied for a certain sand slope were analyzed. The unsaturated slope stability analysis considering suction stress can analyze both conditions of steady infiltration and no infiltration, and it can estimate the safety factor of slope as a function of soil depth. Also, the influence of weathering phenomenon at a certain depth from the ground surface can be considered. The stability analysis considering suction stress was applied to the unsaturated infinite slope composed of sand with the relative density of 60%. The suction stress under no infiltration condition was affected by ground water table until a certain influencing depth. However, the suction stress under steady infiltration condition was affected by seepage throughout the soils. Especially, the maximum suction stress was displayed around ground surface. The factor of safety in the infinite slope under no infiltration condition rapidly increased and decreased within the influence zone of ground water table. As a result of slope stability analysis, the factor of safety is less than 1 at the depth of 2.4 m below the ground surface. It means that the probability of slope failure is too high within the range of depths. The factor of safety under steady infiltration condition is greater than that under no infiltration condition due to the change of suction stress induced by seepage. As the steady infiltration rate of precipitation was getting closer to the saturated hydraulic conductivity, the factor of safety decreased. In case of the steady infiltration rate of precipitation with $-1.8{\times}10^{-3}cm/s$, the factor of safety is less than 1 at the depths between 0.2 m and 3 m below the ground surface. It means that the probability of slope failure is too high within the range of depths, and type of slope failure is likely to be shallow landslides.

• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.6
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• pp.1014-1019
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• 2011

Curcumin is a natural phytochemical present in turmeric, the ground powder of the rhizomes of Curcuma longa. Curcumin has been described as having antioxidant, anti-inflammatory, and anti-carcinogenic properties. However, it is still largely unknown whether curcumin inhibits the UVB-induced inflammatory reaction in HaCaT keratinocyte cell lines. In this study, to confirm the photoprotection properties of curcumin, HaCaT keratinocyte cells were irradiated by UVB, and then treated with curcumin. UVB irradiation induced the increased expressions of IL-$1{\beta}$, TNF-${\alpha}$, IL-6, IL-8, and COX-2 in HaCaT cells. These increased expressions of cytokines (IL-$1{\beta}$, TNF-${\alpha}$, IL-6, IL-8, and COX-2) were down-regulated by curcumin treatment in UVB-irradiated HaCaT cells. In addition skin of hairless mice were damaged by UVB irradiation, which were evidenced by atrophy of epidermis and decrease of collagen in dermis. However, these damages were protected partially by co-treatment of curcumin. Taken together, this data indicate that curcumin may be a promising photoprotection agent, when used in massage pack or sunscreen product, to reduce cell death in UV-damaged skin.

• KIEAE Journal
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• v.15 no.6
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• pp.27-36
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• 2015

Purpose: The definition and factors of passive design being the sustainable method of building plan through the preceding research is deducted and the effect of passive design within the public library by applying the deducted factors in the case of built public libraries and further the realization plan of green library aimed to be reviewed in this research. Method: This study is to induce common elements of architecture plan for public library and passive design, and assess application level of re-classified elements of sustainable public library in order to analyze present condition of passive design applied on facilities of public library. First, related laws and planning standards of public library will be reviewed, then the definition of passive design will be considered using advanced research. Through advanced research related to planing elements and passive design for library induced from various plans for library standards, a common ground of induced passive design element will be transformed into assessment items and practices to be analyzed. Result: Libraries which are and are not preliminarily certified by G-SEED will be compared with each other in order to analyze the effects of passive design on G-SEED. Even though various passive elements such as load reduction of air conditioning and energy efficiency exist, there are no assessment tool within G-SEED. The fact that there are only standards for temporary methods such as utilization of construction material and installation of equipment highlights the challenges in quantitative evaluation.

• Journal of Environmental Health Sciences
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• v.32 no.3
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• pp.227-234
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• 2006

There has been increasing concern in recent years about the occurrence, fate and toxicity of pharmaceutical products in aquatic environment. Although these compounds have been detected in a wide variety of environmental samples including sewage effluent, surface waters, ground water and drinking water, their concentrations generally range from the low ppt to ppb levels. It is therefore often thought to be unlikely that pharmaceuticals will have a detrimental effect on the environment. This study was conducted to determine the endocrine disruption effects of the several pharmaceutical residues in water using adult Japanese medaka (Oryzias latipes). The common antibiotics were used sulfa durgs (sulfamethoxazole and sulfamethazine) and tetracycline drugs (oxytetracycline and tetracycline). Positive control that was induced Vtg (vitellogenin) in male fish was used $17\beta$-estradiol. Vtg was qualified and quantified through Western blotting and ELISA. After SDS gel electrophoresis, the dominant protein band was identified to molecular weight approximately 205 kDa in whole body samples of vitellogenic female. In female medaka exposed to $17\beta$estradiol, there was no significant difference in total protein induction. In contrast, three to five day exposure of male fish to $17\beta$-estradiol resulted in more than 60.0% increase of total protein compared to that of control males (p<0.01). In case of antibiotics, female fish didn't show significant difference, but male fish was showed significant difference. In addition, Vtg induction in male fish was observed with all the test chemicals. On concentrations greater than 0.1 ppm of sulfamethoxazole, 1 ppm of sulfamethazine, 1 ppm of oxytetracycline and 20 ppm of tetracycline, Vtg induction was increased in a dose response manner. This study is one of the early reports suggesting potential endocrine disruption mechanism of antibiotic pharmaceutical products in aquatic ecosystem. Although the effect concentrations obtained from this study were high as unrealistically as in environments, it is endocrine disruption that we should be considered as one of the important consequences of pharmaceutical contamination at water environment, and warrants due attention in future researches.

• Journal of Families and Better Life
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• v.26 no.4
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• pp.55-71
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• 2008

Many studies on the relationships between mothers-in-law and daughters-in-law tended to regard the relationship as a conflicting one. This study, unlike the previous ones, aimed to explore the relationship as it is and to describe the experience of the real relationship. Another aim of this study, on the basis of the results, was to provide the basic data for social services to develop and maintain the positive relationships between mothers and daughters-in-law. To achieve these aims, the central question of the study was, "What are the daughters-in-law's experiences with their mothers-in-law like?" The participants for the study consisted of 12 daughters-in-law who volunteered to be interviewed. Data were collected through in-depth interviews and analyzed according to the grounded theory presented by Strauss and Corbin. As a result, 154 concepts and 42 sub-categories were induced, and finally 18 categories were induced in the course of classifying and integrating these sub-categories. This study discovered that the relationship might be both positive and negative, and that it might even be possible to change from one to the other. The results of the study showed that many factors influenced the quality of the relationship, and that the husband's role was one of the most important factors. Using this study's results as guidance, general programs designed to cultivate more positive relationships between mothers and daughters-in-law can be created and implemented; additionally programs that help the husbands understand the complex relationship and roles can be devised.

• Tunnel and Underground Space
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• v.10 no.4
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• pp.533-543
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• 2000

Deformation behavior and stability of vertical pipeline subjected to underground excavation have been studied by means of numerical analysis. Vortical ground displacements cause the pipe to be compressed, while horizontal ones cause it to be bent. In that region the vertical pipeline meets with the induced compressive stress and bending stress. In addition horizontal rock stress subjected to underground excavation may press the tube in its radial direction and it finally produces the tangential stress of pipe. In this study active gas well system is considered as an example of vertical pipelines. Factor analysis has been conducted which has great influence on the pipeline behavior. Three case studies are investigated which have the different pillar widths and gas well locations in pillar. For example, where overburden depth is 237.5 m and thickness of coal seam is 2.5 m, chain pillar of 45.8 m width in the 3-entry longwall system is proved to maintain safely the outer casing of gas welt which is made of API-55 steel, 10$\frac{3}{4}$ in. diameter and 0.4 in. thickness. Finally an active gas well which was broken by longwall mining is analyzed, where the induced shear stress turn out to exceed the allowable stress of steel.

• Earthquakes and Structures
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• v.6 no.1
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• pp.71-87
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• 2014

Interaction between closely-spaced buildings subject to earthquake induced strong ground motions, termed in the literature as "seismic pounding", occurs commonly during major seismic events in contemporary congested urban environments. Seismic pounding is not taken into account by current codes of practice and is rarely considered in practice at the design stage of new buildings constructed "in contact" with existing ones. Thus far, limited research work has been devoted to quantify the influence of slab-to-slab pounding on the inelastic seismic demands at critical locations of structural members in adjacent structures that are not aligned in series. In this respect, this paper considers a typical case study of a "new" reinforced concrete (R/C) EC8-compliant, torsionally sensitive, 7-story corner building constructed within a block, in bi-lateral contact with two existing R/C 5-story structures with same height floors. A non-linear local plasticity numerical model is developed and a series of non-linear time-history analyses is undertaken considering the corner building "in isolation" from the existing ones (no-pounding case), and in combination with the existing ones (pounding case). Numerical results are reported in terms of averages of ratios of peak inelastic rotation demands at all structural elements (beams, columns, shear walls) at each storey. It is shown that seismic pounding reduces on average the inelastic demands of the structural members at the lower floors of the 7-story building. However, the discrepancy in structural response of the entire block due to torsion-induced, bi-directionally seismic pounding is substantial as a result of the complex nonlinear dynamics of the coupled building block system.

• Journal of the Korean Professional Engineers Association
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• v.23 no.2
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• pp.81-93
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• 1990

The blasting to construct subways in Seoul, Korea. have often increased complaints of ground vibration. In order to prevent the damage to structures, it was necessary to predict the level of blasting induced vibration and to determine the maximum charge weight per delay within a allowable vibration level. A total of 109 blasts were recorded at ten sites. Blast-to-structure distances ranged from 8 to 84.2 meter, where charge weight varied from 0,1125 to 7.85 kg per delay. The data from blast were studied to determine the effect of explosives type on the vibration constants(k). Vibration constants were also analyzed in terms of compressive strength of rock and blasting patterns.

• Journal of Advanced Navigation Technology
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• v.17 no.4
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• pp.429-434
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• 2013

In this paper, the TM (Transverse Magnetic) scattering problems by a perfectly conducting strip grating over a grounded two dielectric layers with edge boundary condition are analyzed by applying the FGMM (Fourier Galerkin Moment Method). For the TM scattering problem, the induced surface current density is expected to the very high value at both edges of the strip, then the induced surface current density on the conductive strip is expanded in a series of the multiplication of the Chebyshev polynomials of the first kind and the functions of appropriate edge boundary condition. Generally, when the value of the relative permittivity of dielectric layers over the ground plane increased, the strip width according to the sharp variation points of the reflected power is shifted to a higher value. The numerical results shown the fast convergent solution and good agreement compared to those of the existing papers.

• Molecular & Cellular Toxicology
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• v.1 no.2
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• pp.99-105
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• 2005

Perchloroethylene (tetrachloroethylene, PCE), a dry cleaning and degreasing solvent, can enter ground-water through accidental leak or spills. PCE can be degraded to trichloroethylene (TCE), 1, 1-dichloroethylene (DCE) and vinyl chloride (VC) as potential bio-product. These compounds have been reported that they can cause clinical diseases and cytotoxicity. However, only a little genotoxic information of these compounds has been known. In this study, we investigated DNA single strand breaks of PCE, TCE, DCE and VC by single cell gel electrophoresis assay, (comet assay) which is a sensitive, reliable and rapid method for DNA single strand breaks with mouse lymphoma L5178Y cells. From these results, $37.5\;{\mu}g/ml$ of PCE, $189\;{\mu}g/ml$ of TCE and $56.4\;{\mu}g/ml$ of DCE were revealed significant DNA damages in the absence of S-9 metabolic activation system meaning direct-acting mutagen. And in the presence of S-9 metabolic activation system, $41.5\;{\mu}g/ml$ of PCE, $328.7\;{\mu}g/ml$ of TCE and $949\;{\mu}g/ml$ of DCE were induced significant DNA damage. In the case of VC, it was revealed a significant DNA damage in the presence of S-9 metabolic activation system. Therefore, we suggest that chloroethylene compounds (PCE, TCE, DCE and VC) may be induced the DNA damage in a mammalian cell.