• BMB Reports
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• 제40권2호
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• pp.247-260
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• 2007

Cinnamate 4-hydroxylase (C4H) is a key enzyme of phenylpropanoid pathway, which synthesizes numerous secondary metabolites to participate in development and adaption. Two C4H isoforms, the 2192-bp BnC4H-1 and 2108-bp BnC4H-2, were cloned from oilseed rape (Brassica napus). They both have two introns and a 1518-bp open reading frame encoding a 505-amino-acid polypeptide. BnC4H-1 is 57.73 kDa with an isoelectric point of 9.11, while 57.75 kDa and 9.13 for BnC4H-2. They share only 80.6% identities on nucleotide level but 96.6% identities and 98.4% positives on protein level. Showing highest homologies to Arabidopsis thaliana C4H, they possess a conserved p450 domain and all P450-featured motifs, and are identical to typical C4Hs at substrate-recognition sites and active site residues. They are most probably associated with endoplasmic reticulum by one or both of the N- and C-terminal transmembrane helices. Phosphorylation may be a necessary post-translational modification. Their secondary structures are dominated by alpha helices and random coils. Most helices locate in the central region, while extended strands mainly distribute before and after this region. Southern blot indicated about 9 or more C4H paralogs in B. napus. In hypocotyl, cotyledon, stem, flower, bud, young- and middle-stage seed, they are co-dominantly expressed. In root and old seed, BnC4H-2 is dominant over BnC4H-1, with a reverse trend in leaf and pericarp. Paralogous C4H numbers in Brassicaceae genomes and possible roles of conserved motifs in 5' UTR and the 2nd intron are discussed.

• Journal of Acupuncture Research
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• 제28권6호
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• pp.43-51
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• 2011

Objectives : The purpose of this research was to investigate the effect of oriental medicine public-health program on frozen shoulder patients. Methods : Oriental medicine public-health program was done to 50 frozen shoulder patients who visited Eumseong-gun public health center. Oriental medicine treatment(twice a week for 12 weeks) and prevention-educaiton program was included in public-health program. The schedule was proceeded from 16th March 2010 to 3rd June 2010. The efficacy of program was measured by visual analog scale (VAS), ROM(range of motion), Apley scratch test and Life function score, sleep quality score of their first and last visit. Then we analyzed the improvement in the same group. Results : 1. In VAS change, program showed statistically significant improvement. 2. In ROM(flexion, extension, abduction, adduction) and apley scratch test, program showed statistically significant improvement. 3. In Life function score, program showed statistically significant improvement. 4. In sleep quality score, program also showed improvement, but didn't do statistical significans. Conclusions : The above results suggest that oriental medicine public-health program can be used as effective method for frozen shoulder's treatment and care.

• 한국학교ㆍ지역보건교육학회지
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• 제19권2호
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• pp.43-52
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• 2018

Objects: In this study, we analyzed the correlation between stress and depression related to the quality of life of one elderly household, and analyzed the influence of stress and depression on the quality of life. In this study, I tried to make a plan for improving the quality of life for one elderly. Methods: In this study, the frequency and percentage according to the general characteristics of one elderly household were frequency analyzed. And the mean and standard deviation of stress, depression, quality of life were analyzed on average. And continuous analysis of stress, depression, quality of life, etc., conducted a technical analysis. Relationship to stress, depression, quality of life, correlation analysis was done. The effect of stress and depression on the quality of life was linear regression analysis. SPSS Version 23.0 was used for analysis. Result: Increased stress and increased depression in elderly single households was a static (+) correlation. And the results of the regression analysis showed that the higher the stress and depression of one elderly household, the lower the quality of life. Conclusion: For the improvement of the quality of life of one elderly household, the government should support stress and depression prevention programs according to sex, age, number of chronic diseases.

• 대한치과보철학회지
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• 제44권4호
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• pp.405-413
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• 2006

Purpose : This study was conducted to evaluate the effect of denture placement on nutrition status and quality of life in the urban elderly Material and method : The first survey was conducted from 45 targeted elderly people(25 experimental group, 20 control). In the first survey, information on general characteristics, chewing ability, food intake and nutrient intake, anthropometric measurement, and degree of satisfaction in life were obtained. The second survey was conducted to evaluate the effect of denture placement with same method as the first survey. Results : Before denture placement, there are no statistical significant differences (in general characteristics, chewing ability, nutrient intake, anthropometric measurement, and degree of satisfaction in life) between experimental group and control. But after denture placement, survey shows that there is statistically significant difference in chewing ability between two groups. The experimental group have higher intake of energy, protein, carbohydrate, iron, and vitamin C. in nutrient intake. And after denture replacement, there is significant improvement in degree of satisfaction in life. After denture placement there are significant changes in agitation and attitude toward own aging according to Lawton's factor classification. Conclusion: In short, this study shows that chewing ability improvement of the elderly has strong positive effects to their food intake, nutrient status and quality of life.

• 품질경영학회지
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• 제32권1호
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• pp.40-62
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• 2004

Recently, salaried company employees have a low desire to work and their quality of work life is deteriorating due to the reorganization of companies, high unemployment rates and insecure factors in politics, economy and society As individuals and companies are pursuing high performance and productivity In severe competition, the quality of personal life is despised. We need to reconsider this phenomenon and prepare for the countermeasures. With these backgrounds, this study performed a literature review and survey together to identify the current status of work desire, demographical differences in the sub factors of work desire and correlation between the sub factors of work desire, and between the work desire lowering factors and Improvement methods in order to improve the quality of work life of salaried company employees in the country.

• 품질경영학회지
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• 제41권3호
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• pp.327-335
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• 2013

Purpose: The purpose of this study is to suggest the modified 'Korean Standard-Quality Excellence Index' model and analyze the improvement effect with survey data by comparing the properness between current and suggested model result. Methods: The collected data through the survey were analyzed using paired t-test and unbalanced ANOVA method for testing the consistency of two customer satisfaction evaluating categories and comparing the current model to suggested model for confirming the improvement of performance. Results: The statistical analysis result shows that adjusted model using prior information improves the consistency between two customer satisfaction in case of short life-cycle product. Also long life-cycle product case, the result shows difference gap decreasing with same direction. Conclusion: Considering statistical model for QEI reflecting the characteristic of product group such as life cycle seems to be meaningful. Since index may be compared yearly base for checking the trend, careful approaching without big change should be considered for application.

• 대한물리의학회지
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• 제15권1호
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• pp.25-32
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• 2020

PURPOSE: This study examined the efficacy of an interferential current (IFC) treatment on the improvement of pain, disability, and quality of life in stroke patients with lumbago. METHODS: A double-blind, randomized clinical trial was conducted on 40 stroke patients with lumbago. The patients were allocated randomly into two groups: the IFC treatment group (n= 20) and the placebo treatment group (n= 20). The IFC group received 30 minutes of IFC treatment on the lumbar region, while the placebo group received IFC treatment but without real electrical stimulation. The intervention was administered five days a week for four weeks. The primary outcomes of pain intensity were measured using a visual analogue scale. The secondary measurements included the Barthel Index, Oswestry Disability Index (ODI), and health-related quality of life (HRQoL). RESULTS: The measurements were conducted before and after the two-week intervention period. Compared to the placebo treatment group, the IFC treatment group showed significantly greater improvement in the pain intensity (p<.05), ODI (p<.05), and SF-36 (p<.05) at the end of the intervention. No significant differences in the Barthel Index were found between the two groups. CONCLUSION: These findings show that an IFC treatment can improve pain, functional ability, and quality of life, highlighting the benefits of somatosensory stimulation from IFC in stroke patients with lumbago.

• Child Health Nursing Research
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• 제12권3호
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• pp.295-303
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• 2006

Purpose: The purpose of this study was to describe the relationship between resilience and health-related quality of life and to identify the effect of resilience on health-related quality of life in children with chronic illness. Method: The participants in this study were 71 children who were seen at one of 3 hospitals, either in outpatient clinics or as admitted patients. The data were collected from March to October, 2005 and descriptive statistics, t-test or ANOVA, Pearson correlation coefficient and stepwise multiple regression were used to analyze the data. Result: Health-related quality of life was slightly low with a mean score of 2.85 (range 1-5). Health-related quality of life was significantly different according to age. There was a significant correlation between resilience and health-related quality of life. Resilience was a predictor of health-related quality of life and accounted for 45% of the variance. Conclusions: Resilience was shown to influence health-related quality of life of children with chronic illness. These findings suggest that the interventions to enhance resilience would be effective for the improvement of health-related quality of life.

• 한국실내디자인학회논문집
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• 제21권1호
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• pp.3-10
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• 2012

There is a growing awareness that physical barriers affect the level of independence of people with disabilities. Many researchers insist that barrier free design could influence independence living and quality of life of the disabled. The purpose of this study is to find out the effects of accessible design features of house and public facilities on quality of life of disabled people. A total of 189 questionnaires from the disabled who visited public welfare facilities was analyzed. In order to find out what variables among accessible features in housing and public spaces impact quality of life, multiple regression analysis was carried using SPSS 14. The results showed that accessible designs significantly influence quality of life of the disable. The main reason in which the disabled have difficulties when they move outside is a lack of accessible amenities and facilities. Particularly in house design, accessible main entrance route and accessible main entrance door, and removal of floor level significantly affects quality of life of the disabled. For public spaces, accessible main entrance and installation of ramp or removal of floor levels of main entrance and corridor increase quality of life people with disabilities. This paper suggested that the improvement in housing and public space, in which regulation or bylaws do not specify, should be made to increase accessibility for life quality of the disabled.

• 대한간호학회지
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• 제48권1호
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• pp.96-108
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• 2018

Purpose: This study aimed to construct and test a hypothetical model of the quality of life of school-age children with asthma based on the health-related quality of life model by Wilson and Cleary. Methods: Data were collected from 205 pairs of pediatric outpatients diagnosed with asthma and their parents in Seoul and Gyeonggi-do from July 2016 to April 2017. The exogenous variables were asthma knowledge, number of accompanying allergic diseases, and social support. The endogenous variables were asthma self-efficacy, asthma symptom control, perceived health status, parental quality of life, and children's quality of life. For data analysis, descriptive statistics, factor analysis, and structural equation modeling were performed. Results: Eighteen of the twenty-four hypotheses selected for the hypothetical model were attentive and supported statistically. Quality of life was explained by asthma self-efficacy, asthma symptom control, perceived health, parental quality of life, and asthma knowledge with 83.5%. Conclusion: Strategies for promoting self-efficacy and enforcing asthma knowledge will be helpful for the improvement of health-related quality of life with school-aged asthmatic children.