• Title/Summary/Keyword: imaging physics

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MOLECULAR GAS AND RADIO JET INTERACTION: A CASE STUDY OF THE SEYFERT 2 AGN M51

  • MATSUSHITA, SATOKI;TRUNG, DINH-V;BOONE, FRDERIC;KRIPS, MELANIE;LIM, JEREMY;MULLER, SEBASTIEN
    • Publications of The Korean Astronomical Society
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    • v.30 no.2
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    • pp.439-442
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    • 2015
  • We observed multiple CO transition lines and the HCN(1-0) line at ~ 1" (~ 34 pc) or higher resolution toward the Seyfert 2 nucleus of M51 using the IRAM Plateau de Bure Interferometer (PdBI) and the Submillimeter Array (SMA). All the images show very similar overall molecular gas distribution; there are two discrete clouds at the eastern and western sides of the nucleus, and the western cloud exhibits an elongated distribution and velocity gradient along the radio jet. In addition, high HCN(1-0)/CO(1-0) brightness temperature ratios of about unity have been observed, especially along the radio jet, similar to those observed in shocked molecular gas in our Galaxy. This strongly indicates that the molecular gas along the jet is shocked, that the radio jet and the molecular gas are interacting, and the jet is entraining both diffuse (CO) and dense (HCN) molecular gas outwards from the circumnuclear region. This is the first clear imaging of the outflowing molecular gas entrained by the AGN jet, and showing the detailed physical status of outflowing molecular gas. Since a relatively high HCN(1-0)/CO(1-0) ratio has been observed in the high velocity wing of ultraluminous infrared galaxies, it can also be explained by a similar mechanism to those we describe here.

Guideline on Acceptance Test and Commissioning of High-Precision External Radiation Therapy Equipment

  • Kim, Juhye;Shin, Dong Oh;Choi, Sang Hyoun;Min, Soonki;Kwon, Nahye;Jung, Unjung;Kim, Dong Wook
    • Progress in Medical Physics
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    • v.29 no.4
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    • pp.123-136
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    • 2018
  • The complex dose distribution and dose transfer characteristics of intensity-modulated radiotherapy increase the importance of precise beam data measurement and review in the acceptance inspection and preparation stages. In this study, we propose a process map for the introduction and installation of high-precision radiotherapy devices and present items and guidelines for risk management at the acceptance test procedure (ATP) and commissioning stages. Based on the ATP of the Varian and Elekta linear accelerators, the ATP items were checked step by step and compared with the quality assurance (QA) test items of the AAPM TG-142 described for the medical accelerator QA. Based on the commissioning procedure, dose quality control protocol, and mechanical quality control protocol presented at international conferences, step-by-step check items and commissioning guidelines were derived. The risk management items at each stage were (1) 21 ionization chamber performance test items and 9 electrometer, cable, and connector inspection items related to the dosimetry system; (2) 34 mechanical and dose-checking items during ATP, 22 multileaf collimator (MLC) items, and 36 imaging system items; and (3) 28 items in the measurement preparation stage and 32 items in the measurement stage after commissioning. Because the items presented in these guidelines are limited in terms of special treatment, items and practitioners can be modified to reflect the clinical needs of the institution. During the system installation, it is recommended that at least two clinically qualified medical physicists (CQMP) perform a double check in compliance with the two-person rule. We expect that this result will be useful as a radiation safety management tool that can prevent radiation accidents at each stage during the introduction of radiotherapy and the system installation process.

b0 Dependent Neuronal Activation in the Diffusion-Based Functional MRI

  • Kim, Hyug-Gi;Jahng, Geon-Ho
    • Progress in Medical Physics
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    • v.30 no.1
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    • pp.22-31
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    • 2019
  • Purpose: To develop a new diffusion-based functional MRI (fMRI) sequence to generate apparent diffusion coefficient (ADC) maps in single excitation and evaluate the contribution of b0 signal on neuronal changes. Materials and Methods: A diffusion-based fMRI sequence was designed with single measurement that can acquire images of three directions at a time, obtaining $b=0s/mm^2$ during the first baseline condition (b0_b), followed by 107 diffusion-weighted imaging (DWI) with $b=600s/mm^2$ during the baseline and visual stimulation conditions, and another $b=0s/mm^2$ during the last activation condition (b0_a). ADC was mapped in three different ways: 1) using b0_b (ADC_b) for all time points, 2) using b0_a (ADC_a) for all time points, and 3) using b0_b and b0_a (ADC_ba) for baseline and stimulation scans, respectively. The fMRI studies were conducted on the brains of 16 young healthy volunteers using visual stimulations in a 3T MRI system. In addition, the blood oxygen level dependent (BOLD) fMRI was also acquired to compare it with diffusion-based fMRI. A sample t-test was used to investigate the voxel-wise average between the subjects. Results: The BOLD data consisted of only activated voxels. However, ADC_ba data was observed in both deactivated and activated voxels. There were no statistically significant activated or deactivated voxels for DWI, ADC_b, and ADC_a. Conclusions: With the new sequence, neuronal activations can be mapped with visual stimulation as compared to the baseline condition in several areas in the brain. We showed that ADC should be mapped using both DWI and b0 images acquired with the same conditions.

STAR FORMATION ACTIVITY OF GALAXIES UNDERGOING RAM PRESSURE STRIPPING IN THE VIRGO CLUSTER

  • Mun, Jae Yeon;Hwang, Ho Seong;Lee, Myung Gyoon;Chung, Aeree;Yoon, Hyein;Lee, Jong Chul
    • Journal of The Korean Astronomical Society
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    • v.54 no.1
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    • pp.17-35
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    • 2021
  • We study galaxies undergoing ram pressure stripping in the Virgo cluster to examine whether we can identify any discernible trend in their star formation activity. We first use 48 galaxies undergoing different stages of stripping based on H i morphology, H i deficiency, and relative extent to the stellar disk, from the VIVA survey. We then employ a new scheme for galaxy classification which combines H i mass fractions and locations in projected phase space, resulting in a new sample of 365 galaxies. We utilize a variety of star formation tracers, which include g - r, WISE [3.4]-[12] colors, and starburstiness that are defined by stellar mass and star formation rates to compare the star formation activity of galaxies at different stripping stages. We find no clear evidence for enhancement in the integrated star formation activity of galaxies undergoing early to active stripping. We are instead able to capture the overall quenching of star formation activity with increasing degree of ram pressure stripping, in agreement with previous studies. Our results suggest that if there is any ram pressure stripping induced enhancement, it is at best locally modest, and galaxies undergoing enhancement make up a small fraction of the total sample. Our results also indicate that it is possible to trace galaxies at different stages of stripping with the combination of H i gas content and location in projected phase space, which can be extended to other galaxy clusters that lack high-resolution H i imaging.

RELATION BETWEEN BLACK HOLE MASS AND BULGE LUMINOSITY IN HARD X-RAY SELECTED TYPE 1 AGNS

  • Son, Suyeon;Kim, Minjin;Barth, Aaron J.;Ho, Luis C.
    • Journal of The Korean Astronomical Society
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    • v.55 no.2
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    • pp.37-57
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    • 2022
  • Using I-band images of 35 nearby (z < 0.1) type 1 active galactic nuclei (AGNs) obtained with Hubble Space Telescope, selected from the 70-month Swift-BAT X-ray source catalog, we investigate the photometric properties of the host galaxies. With a careful treatment of the point-spread function (PSF) model and imaging decomposition, we robustly measure the I-band brightness and the effective radius of bulges in our sample. Along with black hole (BH) mass estimates from single-epoch spectroscopic data, we present the relation between BH mass and I-band bulge luminosity (MBH-MI,bul relation) of our sample AGNs. We find that our sample lies offset from the MBH-MI,bul relation of inactive galaxies by 0.4 dex, i.e., at a given bulge luminosity, the BH mass of our sample is systematically smaller than that of inactive galaxies. We also demonstrate that the zero point offset in the MBH-MI,bul relation with respect to inactive galaxies is correlated with the Eddington ratio. Based on the Kormendy relation, we find that the mean surface brightness of ellipticals and classical bulges in our sample is comparable to that of normal galaxies, revealing that bulge brightness is not enhanced in our sample. As a result, we conclude that the deviation in the MBH-MI,bul relation from inactive galaxies is possibly because the scaling factor in the virial BH mass estimator depends on the Eddington ratio.

Evaluation of Treatment Plan Quality between Magnetic Resonance-Guided Radiotherapy and Volumetric Modulated Arc Therapy for Prostate Cancer

  • Chang Heon Choi;Jin Ho Kim;Jaeman Son;Jong Min Park;Jung-in Kim
    • Progress in Medical Physics
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    • v.33 no.4
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    • pp.121-128
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    • 2022
  • Purpose: This study evaluated the quality of plans based on magnetic resonance-guided radiotherapy (MRgRT) tri-Co-60, linac, and conventional linac-based volumetric modulated arc therapy (linac-VMAT) for prostate cancer. Methods: Twenty patients suffering from prostate cancer with intermediate risk who were treated by MAT were selected. Additional treatment plans (primary and boost plans) were generated based on MRgRT-tri-Co-60 and MRgRT-linac. The planning target volume (PTV) of MRgRT-based plans was created by adding a 3 mm margin from the clinical target volume (CTV) due to high soft-tissue contrast and real-time motion imaging. On the other hand, the PTV of conventional linac was generated based on a 1 cm margin from CTV. The targets of primary and boost plans were prostate plus seminal vesicle and prostate only, respectively. All plans were normalized to cover 95% of the target volume by 100% of the prescribed dose. Dosimetric characteristics were evaluated for each of the primary, boost, and sum plans. Results: For target coverage and conformity, the three plans showed similar results. In the sum plans, the average value of V65Gy of the rectum of MRgRT-linac (2.62%±2.21%) was smaller than those of MRgRT tri-Co-60 (9.04%±3.01%) and linac-VMAT (9.73%±7.14%) (P<0.001). In the case of bladder, the average value of V65Gy of MRgRT-linac was also smaller. Conclusions: In terms of organs at risk sparing, MRgRT-linac shows the best value while maintaining comparable target coverage among the three plans.

Influence of Two-Dimensional and Three-Dimensional Acquisitions of Radiomic Features for Prediction Accuracy

  • Ryohei Fukui;Ryutarou Matsuura;Katsuhiro Kida;Sachiko Goto
    • Progress in Medical Physics
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    • v.34 no.3
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    • pp.23-32
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    • 2023
  • Purpose: In radiomics analysis, to evaluate features, and predict genetic characteristics and survival time, the pixel values of lesions depicted in computed tomography (CT) and magnetic resonance imaging (MRI) images are used. CT and MRI offer three-dimensional images, thus producing three-dimensional features (Features_3d) as output. However, in reports, the superiority between Features_3d and two-dimensional features (Features_2d) is distinct. In this study, we aimed to investigate whether a difference exists in the prediction accuracy of radiomics analysis of lung cancer using Features_2d and Features_3d. Methods: A total of 38 cases of large cell carcinoma (LCC) and 40 cases of squamous cell carcinoma (SCC) were selected for this study. Two- and three-dimensional lesion segmentations were performed. A total of 774 features were obtained. Using least absolute shrinkage and selection operator regression, seven Features_2d and six Features_3d were obtained. Results: Linear discriminant analysis revealed that the sensitivities of Features_2d and Features_3d to LCC were 86.8% and 89.5%, respectively. The coefficients of determination through multiple regression analysis and the areas under the receiver operating characteristic curve (AUC) were 0.68 and 0.70 and 0.93 and 0.94, respectively. The P-value of the estimated AUC was 0.87. Conclusions: No difference was found in the prediction accuracy for LCC and SCC between Features_2d and Features_3d.

Multi-focus 3D display of see-through Head-Mounted Display type (투시형 두부 장착형 디스플레이방식의 다초점 3차원 디스플레이)

  • Kim, Dong-Wook;Yoon, Seon-Kyu;Kim, Sung-Kyu
    • Journal of Broadcast Engineering
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    • v.11 no.4 s.33
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    • pp.441-447
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    • 2006
  • See-through HMD type 3D display can provide an advantage of us seeing virtual 3D data used stereoscopic display simultaneously with real object(MR-Mixed Reality). But, when user sees stereoscopic display for a long time, not only eye fatigue phenomenon happens but also de-focus phenomenon of data happens by fixed focal point of virtual data. Dissatisfaction of focus adjustment of eye can be considered as the important reason of this phenomenon. In this paper, We proposed an application of multi-focus in see-through HMD as a solution of this problem. As a result, we confirmed that the focus adjustment coincide between the object of real world and the virtual data by multi-focus in monocular condition.

SPATIAL AND ENERGY RESOLUTIONS OF A HEXAGONAL ANIMAL PET SCANNER BASED ON LGSO CRYSTAL AND FLAT-PANEL PMT

  • Lee, Chan-Mi;Hong, Seong-Jong;Yoon, Hyun-Suk;Ito, Mikiko;Kwon, Sun-Il;Park, Sang-Keun;Lee, Dong-Soo;Sim, Kwang-Souk;Lee, Jae-Sung
    • Nuclear Engineering and Technology
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    • v.44 no.1
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    • pp.53-60
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    • 2012
  • The aim of this study was to explore the spatial and energy resolutions of a PET scanner that we have recently developed. The scanner, which consists of six detector modules with 1-layer LGSO crystals, has a hexagonal configuration with a faceto- face distance of 86.4 mm between two opposite PET modules; such properties facilitate the imaging of small animals. A $^{22}Na$ point source was employed to estimate horizontal and vertical spatial resolutions. To assess the energy resolution, a uniform $^{18}F$ cylindrical phantom was scanned. A software-based spectrum analysis of list-mode data was used to assign a local energy window centered on the photopeak position for every single crystal. For the image reconstruction, an ML-EM algorithm was used. The spatial resolutions at the center of the scanner were 0.99 mm in the horizontal direction and 1.13 mm in the vertical direction. The energy resolution averaged over each PMT ranged from 13.3%-14.3%, which gave an average value of 13.8%. These results show that this simple system is promising for small animal imaging with excellent spatial and energy resolutions.

FABRICATION AND ALIGNMENT OF PARTS OF THE KASINICS OFFNER SYSTEM (KASINICS 오프닝 광학계의 부품 가공 및 정렬)

  • Mok, Seung-Won;Lee, Sung-Ho;Yuk, In-Soo;Park, Young-Sik;Jin, Ho;Han, Jeong-Yeo;Moon, Bong-Kon;Cha, Sang-Mok;Kim, Geon-Hee;Im, Myung-Shin
    • Publications of The Korean Astronomical Society
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    • v.21 no.2
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    • pp.43-49
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    • 2006
  • The KASINICS (KASI Near Infrared Camera System) is a ground-based Near-Infrared (NIR) imaging instrument developed by the Korea Astronomy and Space Science Institute (KASI). In this paper, we report the test results of the KASINICS camera optics system which is comprised of a 1-1 Offner relay. We measure that the surface RMS fluctuations of the Offner mirrors are at the level of $10^{-1}-10^{-2}$ of the target wavelengths, showing that the mirrors are sufficiently smooth for NIR observations. The alignment of the Offner optics system has been checked too. Our ray-tracing simulations find that the image quality should not degrade more than the pixel size of the KASINICS ($40{\mu}m$), if a de-centering or a tilt of the Offner mirrors are within 5mm, or $2.5^{\circ}$. Our measurement shows that the de-centering or the tilt of the Offner mirrors are less than 1 mm or $0.5^{\circ}$, assuring that the KASINICS image quality are not affected by the alignment errors. We have also measured that the optics resolution is $20{\mu}m$ and it does not degrade more than 10% over the detector surface area of 14.3 mm ${/times}$ 14.3mm. Overall, we conclude that the KASINICS optics system satisfies the design requirements for NIR imaging observations.