• Childhood Kidney Diseases
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• v.19 no.1
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• pp.8-13
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• 2015

Antenatal hydronephrosis (ANH) is one of the most common abnormal findings detected on prenatal ultrasound (US), and it has been reported in 1-5% of all pregnancies. The likelihood of significant postnatal pathologic abnormality in the urinary tract correlates with the degree of anterior-posterior diameter (APD) according to the gestational age. Detection of urologic anomalies prenatally permits fetal interventions that avoid complications in rare cases of bladder outlet obstruction with oligohydramnios even though their final benefits still remain controversial. There is no clear consensus on the extent and mode of postnatal imaging after a diagnosis of ANH. US is the mainstay of the postnatal evaluation and helps guide further testing with voiding cystourethrography (VCUG) and diuretic renography. Although most algorithms continue to recommend generous VCUG for identification of lower urinary tract anomalies, VCUG may be safely reserved for high grade ANH cases or any grade of ANH with dilated distal ureter without increasing the risk of urinary tract infection (UTI). There are conflicting studies about efficacy of postnatal prophylactic antibiotics. It still seems reasonable to consider use of a prophylactic antibiotic to prevent infant UTIs in high-risk populations, such as females and uncircumcised males with high grades of hydronephrosis, hydroureteronephrosis, or vesicouretral reflux.

• Clinical and Experimental Pediatrics
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• v.56 no.3
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• pp.101-106
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• 2013

Despite developments in surgical techniques and other interventions, right ventricular (RV) failure remains an important clinical problem in several congenital heart diseases (CHD). RV function is one of the most important predictors of mortality and morbidity in patients with CHD. RV failure is a progressive disorder that begins with myocardial injury or stress, neurohormonal activation, cytokine activation, altered gene expression, and ventricular remodeling. Pressure-overload RV failure caused by RV outflow tract obstruction after total correction of tetralogy of Fallot, pulmonary stenosis, atrial switch operation for transposition of the great arteries, congenitally corrected transposition of the great arteries, and systemic RV failure after the Fontan operation. Volume-overload RV failure may be caused by atrial septal defect, pulmonary regurgitation, or tricuspid regurgitation. Although the measurement of RV function is difficult because of many reasons, the right ventricle can be evaluated using both imaging and functional modalities. In clinical practice, echocardiography is the primary mode for the evaluation of RV structure and function. Cardiac magnetic resonance imaging is increasingly used for evaluating RV structure and function. A comprehensive evaluation of RV function may lead to early and optimal management of RV failure in patients with CHD.

• The Journal of the Acoustical Society of Korea
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• v.31 no.8
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• pp.580-589
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• 2012

In this paper, we studied on Doppler gap-filling algorithms suitable for a portable or low-cost medical ultrasound imaging system, and as a result, found out algorithms based on mirroring or autoregressive model. Moreover, controlling the computational demand in the proper range, we improved the performances of these algorithms by solving their problems. Effectiveness of these modified algorithms is verified by computer simulations and experiments which used artificially generated Doppler signals and Doppler data acquired from human body through an actual ultrasound system.

• Journal of The Korean Astronomical Society
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• v.29 no.spc1
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• pp.389-390
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• 1996

The CCDs are widely used in astronomical observations either in direct imaging use or spectroscopic mode. However, the areas of available sensors are too small for large imaging format. One possibility to obtain large detection area is to assemble mosaics of CCD, and drive them simultaneously. Parallel driving of many CCDs together rules out the possibility of individual tuning; however, such optimisation is very important, when the ultimate low light level performance is required, particularly for new, or mixed devices. In this work, a new concept is explored for an entirely novel approach, where the drive waveforms are multiplexed and interleaved. This simultaneously reduces the number of leadout connections and permits individual optimisation efficiently. The digital controller can be designed within a single EPLD (Erasable Programmable Logic Device) chip produced by a CAD software package, where most of the digital controller circuits are integrated. This method can minimise the component. count., and improve the system efficiency greatly, based on earlier works by Han et a1. (1996, 1994). The system software has an open architecture to permit convenient modification by the user, to fit their specific purposes. Some variable system control parameters can be selected by a user with a wider range of choice. The digital controller design concept allows great flexibility of system parameters by the software, specifically for the compatibility to deal with any number of mixed CCDs, and in any format, within the practical limit.

• The Bulletin of The Korean Astronomical Society
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• v.43 no.1
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• pp.40.1-40.1
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• 2018

외계행성 탐색시스템 18k 모자이크 CCD 카메라는 4개의 9k CCD로 구성되며 총 32개 채널의 영상영역과 리드아웃 회로를 가진다. 관측 영상에는 각 영상영역에 대한 오버스캔(overscan) 영역이 포함되는데, 영상 신호에 의한 오버스캔 영역의 바이어스(bias) 교란을 최소화하기 위해 리드아웃 회로의 인버팅 앰프에 대한 Common Mode Rejection Ratio(CMRR)를 미세 조정하였다. 그 결과 세 사이트의 평균 CMRR이 55 dB에서 73 dB로 향상되었고, 기존에는 영상 신호에 따른 오버스캔 바이어스 레벨의 선형적 관계가 약 2/1,000의 기울기를 가졌으나 조정 후에는 약 2/10,000로 바이어스 오차가 줄어들었다. CCD 리드아웃 회로의 미세조정과 클락(clock) 개선을 통해 물결무늬 잡음 제거 및 읽기 잡음 감소가 이루어졌으며, 향후의 추가적인 바이어스 안정화와 크로스톡 개선 방안이 검토되고 있다. 카메라 전자부 조정 과정 및 결과와 더불어, 카메라 듀어와 부대장비 유지보수, Polycold CryoTiger 냉각기 운영 및 개선 관련 노하우도 함께 발표한다.

• Publications of The Korean Astronomical Society
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• v.27 no.3
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• pp.87-93
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• 2012

A low-dispersion fiber feed Littrow-mounted grating spectrometer for education was designed and fabricated. The dispersion element is a reflective type blazed grating Edmundoptics NT 46-075 (spatial frequency 600 lines/mm, dimension $30mm{\times}30mm$, blazed angle 8.6 degree). The optical fiber coupler module for optical guiding from telescope to spectrometer is composed of a multi-mode FC connector - FC connector optical fiber patch cord (core/cladding diameter $50{\mu}m/125{\mu}m$) and two 1.25" throw-tube couplers. The lens for collimating and imaging is a general purpose focal length 50 mm camera lens (f/1.8). The device for optical path control is a rectangular prism (size $25mm{\times}25mm$). The imaging camera sensor is a Meade DSI Pro 2 CCD sensor (black and white, $752{\times}582$ pixels and pixel size $8.3{\mu}m{\times}8.6{\mu}m$). Softwares for data logging and analysis consist of Meade Autostar Suite, NIH imagej and Vernier Logger Pro 3. The wavelength coverage range of the spectrometer is 205 nm at central wavelength 550 nm. The wavelength resolution is 1.7 nm.

• Proceedings of the KAIS Fall Conference
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• 2010.05a
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• pp.108-112
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• 2010

Confocal Imaging System is an essential machine for a wide range of inspection wafer. For concurrent and fast acquiring the image data of four channels, the new image acquisition system used the protocol of camera-link standard with the full mode of configuration in interconnection with a frame grabber integrated in a computer, which is popularly used for many cameras, so the programming environment of image processing is optional such as Visual C++, Matlab. In addition, many conventional methods were coordinately used for contribution to build the high quality of images for precise processing analog signals of PhotoMutiplier Tubes(PMTs), accurate control of scanning device, sensitivity of PMTs, and laser source. The prototype of new image acquisition system, could meet the goal of development, it is used in LSCM for high content screening to investigation the processes of elements of living specimens at the same time by simultaneous grab image data on 4 PMTs channels.

• Parasites, Hosts and Diseases
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• v.46 no.3
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• pp.139-143
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• 2008

Ingestion of raw animal liver has been suggested as a possible mode of infection of human toxocariasis, We evaluated the relationship between toxocariasis and the ingestion of raw meat in patients with eosinophilia of unknown etiology. The study population consisted of 120 patients presenting with peripheral blood eosinophilia (> $500\;cells/{\mu}l$ or > 10% of the white blood cell count). They were divided into 2 groups: 104 seropositive patients based on a Toxocara excretory-secretory IgG ELISA and 16 seronegative patients. While 25.0% of seronegative patients had a recent history of eating raw cow liver, 87.5% of seropositive patients had this history. Multivariate statistical analysis showed that a recent history of eating raw cow liver was related to an increased risk of toxocariasis. Collectively, it is proposed that raw cow liver is a significant infection source of toxocariasis in the patients with eosinophilia of unknown etiology.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2005.11a
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• pp.879-882
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• 2005

This paper shows a method for design of the nano-positioning planar scanner used in the scanning probe microscope. The planar scanner is composed of flexure guides, piezoelectric actuators and feedback sensors. In the design of flexure guides, the Castigliano's theorem was used to find the stiffness of the guide. The motion amplifying mechanism was used in the piezoelectric actuator to achieve a large travel range. We found theoretically the travel range of the total system and verified using the commercial FEM(Finite element method) program. The maximum travel range of the planar scanner is above than 140 $\mu$m. The 3 axis positioning capability was verified by the mode analysis using the FEM program. Moreover, we presented the actual AFM(Atomic Force Microscope) imaging results with up to 2Hz imaging scan rate. Experimental results show that the properties of the proposed planar scanner is well enough to be used in SPM applications like AFM.

• Journal of Biomedical Engineering Research
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• v.26 no.1
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• pp.55-63
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• 2005

A novel imaging system for High-resolution Ultrasonic Transmission Tomography (HUTT) and soft tissue differentiation methodology for the HUTT system are presented. The critical innovation of the HUTT system includes the use of sub-millimeter transducer elements for both transmitter and receiver arrays and multi-band analysis of the first-arrival pulse. The first-arrival pulse is detected and extracted from the received signal (i.e., snippet) at each azimuthal and angular location of a mechanical tomographic scanner in transmission mode. Each extracted snippet is processed to yield a multi-spectral vector of attenuation values at multiple frequency bands. These vectors form a 3-D sinogram representing a multi-spectral augmentation of the conventional 2-D sinogram. A filtered backprojection algorithm is used to reconstruct a stack of multi-spectral images for each 2-D tomographic slice that allow tissue characterization. A novel methodology for soft tissue differentiation using spectral target detection is presented. The representative 2-D and 3-D HUTT images formed at various frequency bands demonstrate the high-resolution capability of the system. It is shown that spherical objects with diameter down to 0.3㎜ can be detected. In addition, the results of soft tissue differentiation and characterization demonstrate the feasibility of quantitative soft tissue analysis for possible detection of lesions or cancerous tissue.