• Title/Summary/Keyword: ice-2

Search Result 1,281, Processing Time 0.031 seconds

Screening and Biotransformation of Interleukin-1$\beta$ Converting Enzyme Production Inhibitors from Arctii fructus

  • KIM HYUN A;YOON DO YOUNG;LEE SANG MYUNG;BAEK SEUNG HWA;HAN GYOON HEE;KHO YOUNG HEE;LEE CHOONG HWAN
    • Journal of Microbiology and Biotechnology
    • /
    • v.15 no.2
    • /
    • pp.269-273
    • /
    • 2005
  • Five dibenzylbutyrolactones were isolated from a methanol extract of Arctii fructus (Arctium lappa L.) by bioassay-guided isolation, using the interleukin-l $\beta$ converting enzyme (caspase-l, ICE) production inhibitory assay in vitro. These compounds were spectroscopically identified as lappaol E (1), lappaol A (2), matairesinol (3), arctigenin (4), and arctiin (5). Among the compounds tested, arctigenin (4) showed the strongest inhibitory activity for ICE production in IL-$\beta$-induced proliferation of D 1 OS cells. Western blot analysis demonstrated that the arctigenin suppressed the expression of ICE protein in a dose-dependent manner. To estimate the biotransformation of Arctii fructus in vivo by human intestinal bacteria, we carried out an anaerobic incubation of the Arctii fructus extract with a human fecal suspension. From the HPLC analysis of metabolites, Arctiin (IC$_{50}$=74.2$\mu$g/ml), a major component of Arctii fructus, was transformed to aglycone, arctigenin (IC$_{50}$=12.5$\mu$g/ml), by human intestinal bacteria. The ICE production inhibitory activity of Arctii fructus would be much stronger in vivo than in vitro due to the biotransformation by human intestinal bacteria.

Measurement of Aerosols and Ice Clouds Using Ellipsometry Lidar (타원편광 라이다 개발 및 이를 이용한 에어로졸과 구름의 특성 측정)

  • Kim, Dukhyeon;Cheong, Hai Du;Volkov, Sergei N.
    • Korean Journal of Optics and Photonics
    • /
    • v.26 no.1
    • /
    • pp.9-16
    • /
    • 2015
  • We have developed ellipsometry lidar and measured aerosol and ice-cloud characteristics. To measure a full normalized backscattering phase matrix (NBSPM) composed of nine elements, we have designed an optical system with three kinds of transmission and three kinds of reception, composed of ${\lambda}/2$ waveplate, ${\lambda}/4$ waveplate and empty optic. To find systematic optical errors, we used clean day middle-altitude (4-6km) lidar signals for which the aerosol's concentration was small and its orientation chaotic. After calibrating our lidar system, we have calculated NBSPM elements scattered from an aerosol and from an ice cloud. In the case of an aerosol, we found that the off-diagonal values $m_{12},{\ldots},m_{34}$ of the NBSPM are smaller than those for a cirrus cloud. Also, the off-diagonal values of the NBSPM from a cirrus cloud depend on atmospheric conditions.

Effect of molecular and crystalline structure on phase transition behaviors of rice starches (쌀전분의 분자 및 결정구조가 상전이에 미치는 영향)

  • Jeong, Duyun;Lee, Su-Jin;Chung, Hyun-Jung
    • Korean Journal of Food Science and Technology
    • /
    • v.51 no.5
    • /
    • pp.432-437
    • /
    • 2019
  • The objective of this study was to determine the molecular/crystalline structures and phase transition properties of starches isolated from six rice cultivars grown in Korea. Apparent amylose content was highest in starch obtained from the Saemimyeon cultivar (30.8%) and lowest in that obtained from the Sheonhyangheukmi cultivar (20.3%). Starch from the Saemimyeon cultivar had a lower proportion of short chains (DP 6-12) and a the higher proportion of long chains (DP${\geq}37$) than that seen in other rice starches. Saemimyeon had relatively higher pasting temperature ($86.5^{\circ}C$), gelatinization temperature ($72.1^{\circ}C$) and gelatinization enthalpy (14.2 J/g) than these values found for other rice starches. The onset temperature and enthalpy for ice crystallization of rice starch ranged from $-27.1{\sim}-20.2^{\circ}C$ and 241.1~264.8 J/g, respectively. The ice melting enthalpy measured in excess water (67% water content) of rice starches was 282.4~310.1 J/g. Among the rice starches examined, starch obtained from Sheonhyangheukmi, with the lowest amylose content, showed the lowest glass transition temperature (${T_g}^{\prime}$).

"Dust, Ice and Gas In Time" (DIGIT): Embedded Objects

  • Lee, Jeong-Eun;DIGIT team, DIGIT team
    • The Bulletin of The Korean Astronomical Society
    • /
    • v.37 no.1
    • /
    • pp.81.1-81.1
    • /
    • 2012
  • Herschel Key Program 중의 하나인 "Dust, Ice and Gas In Time (DIGIT)"의 관측 및 분석결과를 발표하고자 한다. 특히 DIGIT 천체들 중 Photodetector Array Camera and Spectrometer (PACS)로 관측된 별생성 초기 단계에 있는 embedded objects들의 FIR SED와 CO, $H_2O$, OH, [OI], [CII]의 FIR 천이선들의 공간분포와 생성기작을 분석한다. 뿐만 아니라, 원시성의 특성들($L_{bol}$$T_{bol}$)과 이들 각 분자/원자선에 의한 냉각률의 관계를 통계적으로 분석한 결과를 제시한다.

  • PDF

Changes Detection of Ice Dimension in Cheonji, Baekdu Mountain Using Sentinel-1 Image Classification (Sentinel-1 위성의 영상 분류 기법을 이용한 백두산 천지의 얼음 면적 변화 탐지)

  • Park, Sungjae;Eom, Jinah;Ko, Bokyun;Park, Jeong-Won;Lee, Chang-Wook
    • Journal of the Korean earth science society
    • /
    • v.41 no.1
    • /
    • pp.31-39
    • /
    • 2020
  • Cheonji, the largest caldera lake in Asia, is located at the summit of Baekdu Mountain. Cheonji is covered with snow and ice for about six months of the year due to its high altitude and its surrounding environment. Since most of the sources of water are from groundwater, the water temperature is closely related to the volcanic activity. However, in the 2000s, many volcanic activities have been monitored on the mountain. In this study, we analyzed the dimension of ice produced during winter in Baekdu Mountain using Sentinel-1 satellite image data provided by the European Space Agency (ESA). In order to calculate the dimension of ice from the backscatter image of the Sentinel-1 satellite, 20 Gray-Level Co-occurrence Matrix (GLCM) layers were generated from two polarization images using texture analysis. The method used in calculating the area was utilized with the Support Vector Machine (SVM) algorithm to classify the GLCM layer which is to calculate the dimension of ice in the image. Also, the calculated area was correlated with temperature data obtained from Samjiyeon weather station. This study could be used as a basis for suggesting an alternative to the new method of calculating the area of ice before using a long-term time series analysis on a full scale.

Differences in Body Temperatures according to Three Methods of cold Application (냉적용 방법에 따른 심부 및 피부온도변화)

  • 임난영;김진경
    • Journal of Korean Academy of Nursing
    • /
    • v.23 no.2
    • /
    • pp.157-169
    • /
    • 1993
  • The most effective modality for cold application and the length of the application have not been determined despite many studies about the use of cold. A quasi-experimental study was conducted to examine the most effective modality among three methods of cold application, the most effective length of time for the application and the continuing effect after each type of cold application. Thirty adult patients admitted to medical and neurosurgical unit and with high fever (above 38.2 ℃) were assigned randomly to each of three cold ap-plication methods : (a) ice bag: (b) cold compress; and (c) tepid water sponge bath. Each method was applied to the whole anterior surface except the face and neck with the patient in the supine pos-ition. Rectal temperatures and skin temperatures (mid chest, upper arm, thigh and leg) were measured be-fore each application and every 10 minutes during ,each application for a period of 60 minutes. They were also measured every 10 minutes for 30 minutes after each cold application was finished. The experiments were carried out from Dec. 22. 1992 through Feb. 26, 1993. The data were analysed using means, ANCOVA Sheffe test and Pearson's Correlation Coefficient. The results of this study are as follows : 1. There were no significant differences among the three cold application methods in the reduction of body temperature, 2. Among the ice bag, cold compress and tepid water sponge bath groups, the ice bag proved to be the most effective method for lowering skin temperature while the cold compress was least effective. 3. Both rectal and skin temperature continued to decrease during the 60 minutes of cold application, but the hunting phenomena was not observed at any of the cold application sites. 4. There were no significant correlations between mean rectal and skin temperatures. 5. Skin temperatures according to the cold application sites decreased to a range of 3.46℃ to 5.20℃ (mid chest), a range of 4.48℃ 4.96℃ (upper arm), a range of 3.86℃ to 5.05℃ (thigh), and a range of 5.42℃ -7.12℃ (leg ). 6. In continuing effect after the cold applications were finished, rectal temperatures according to ice bag, cold compress and tepid sponge bath decreased to 0.29℃, 0.23℃ and 0.09℃ respectively, while the mean skin temperatures increased to 2.39℃ , 2.04℃ and 2.22℃ respectively. In this experiment the ice bag was the most effective modality for lowering skin temperature. when-ever cold is applied for systemic effect, the continuing effect of cold should be considered. The determination of the most effective length of time for cold application needs further study.

  • PDF

Effects of local cold application on tissue & peripheral oxygen saturation, peripheral blood flow, skin temperature, and body temperature of healthy adult (국소적 냉 요법이 정상 성인의 조직과 말초의 산소포화도, 말초 혈류, 피부 온도, 체온에 미치는 효과)

  • Kim, Seung Ok;Shin, Yong Soon
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.21 no.10
    • /
    • pp.127-136
    • /
    • 2020
  • Purpose: This study aimed to establish a basis for application time and cold therapy interval by checking the physiological changes after applying a cold-gel and ice pack, commonly applied to cold therapy, and after passive rewarming. Method: A total of 22 healthy adults used cold-gel packs and ice packs in a Randomized control group repeated measurement study, and passive rewarming was performed for 40 minutes after 30 minutes of cold therapy. After applying to the right axilla, StO2, SpO2, peripheral blood flow, skin and body temperature were measured 15 times every 5 minutes. Result: In the cold-gel pack group, StO2 decreased from 69.43% to 61.06% after 30 minutes application, and in the ice pack group, StO2 decreased from 67.66% to 64.80% (p <001). In the cold-gel pack group, skin temperature decreased from 33.57℃ to 29.15℃ after 30 minutes application, and in the ice pack group, skin temperature decreased from 32.64℃ to 28.90℃ (p <.001). Only skin temperature recovered completely after 40 minutes of rewarming. There were insignificant differences between the cold-gel pack and ice pack. Conclusion: When applying cold therapy to the axillary, at least 40 minutes for passive rewarming is necessary after 30 minutes of application.

Effect of Freezing Conditions on the Formation of Ice Crystals in Food during Freezing Process (식품의 동결중에 생성되는 빙결정에 미치는 동결조건의 영향)

  • 공재열;김정한;김민용;배승권
    • Journal of the Korean Society of Food Science and Nutrition
    • /
    • v.21 no.2
    • /
    • pp.213-218
    • /
    • 1992
  • The reaching time to the freezing point was to be fast in the order of 2% agar gel, 5% agar gel, 20% gelatin gel, pork, respectively. The freezing time and the passing time through the zone of the maximum ice crystal formation had linear relationship with the coolant temperature. The average diameter d$_{p}$ of ice crystal in a soybean protein gel and the moving of freezing front were represented an inverse proportion, and the moving velocity of freezing front was shown as 3.4$\times$10$^{-6}$ $\textrm{cm}^2$/sec from predicted theoretical formula. This value was very close to experimental results. The storage temperature did not give any influences for the growth of ice crystal in inside soybean protein gels during freezing conservation. The relationship between freezing condition and structure of freezing front was as follows : (moving velocity of freezing front) : (mass transfer rate of water at freezing point)$\times$(surface area of freezing front).

  • PDF

Observation of Ice Gradient in Cheonji, Baekdu Mountain Using Modified U-Net from Landsat -5/-7/-8 Images (Landsat 위성 영상으로부터 Modified U-Net을 이용한 백두산 천지 얼음변화도 관측)

  • Lee, Eu-Ru;Lee, Ha-Seong;Park, Sun-Cheon;Jung, Hyung-Sup
    • Korean Journal of Remote Sensing
    • /
    • v.38 no.6_2
    • /
    • pp.1691-1707
    • /
    • 2022
  • Cheonji Lake, the caldera of Baekdu Mountain, located on the border of the Korean Peninsula and China, alternates between melting and freezing seasonally. There is a magma chamber beneath Cheonji, and variations in the magma chamber cause volcanic antecedents such as changes in the temperature and water pressure of hot spring water. Consequently, there is an abnormal region in Cheonji where ice melts quicker than in other areas, freezes late even during the freezing period, and has a high-temperature water surface. The abnormal area is a discharge region for hot spring water, and its ice gradient may be used to monitor volcanic activity. However, due to geographical, political and spatial issues, periodic observation of abnormal regions of Cheonji is limited. In this study, the degree of ice change in the optimal region was quantified using a Landsat -5/-7/-8 optical satellite image and a Modified U-Net regression model. From January 22, 1985 to December 8, 2020, the Visible and Near Infrared (VNIR) band of 83 Landsat images including anomalous regions was utilized. Using the relative spectral reflectance of water and ice in the VNIR band, unique data were generated for quantitative ice variability monitoring. To preserve as much information as possible from the visible and near-infrared bands, ice gradient was noticed by applying it to U-Net with two encoders, achieving good prediction accuracy with a Root Mean Square Error (RMSE) of 140 and a correlation value of 0.9968. Since the ice change value can be seen with high precision from Landsat images using Modified U-Net in the future may be utilized as one of the methods to monitor Baekdu Mountain's volcanic activity, and a more specific volcano monitoring system can be built.