• Journal of Korean Port Research
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• v.8 no.1
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• pp.17-22
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• 1994

The wave interaction with flexible membrane such as PVC and fabrics is studied to prove its applicability to portable breakwaters. To obtain the wave exciting force acting on flexible membrane, eigen-function expansion method is employed. The effect of flexible is involved in body boundary condition in which x-directional displacement of membrane is obtained by solving the linear membrane equation. Displacement of membrane is assumed to be small compared to wavelength, therefore the tensile force of membrane remains constant. As the numerical examples, transmission and reflection coefficients according to the change of tensile forces are investigated. The hydrodynamic force on membrane, the dynamic tension in the mooring lines and the vertical displacement profile of membrane are also calculated. It is suggested that the flexible membrane can be used to engineering material for the future coastal/ocean applications.

• Journal of applied mathematics & informatics
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• v.40 no.3_4
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• pp.709-717
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• 2022

The objective of this research is to prove that an additive mapping T : R → R is a left as well as right centralizer on R if it satisfies any one of the following identities: (i) T(xⁿyⁿ + yⁿxⁿ) = T(xⁿ)yⁿ + yⁿT(xⁿ) (ii) 2T(xⁿyⁿ) = T(xⁿ)yⁿ + yⁿT(xⁿ) for each x, y ∈ R, where n ≥ 1 is a fixed integer and R is any n!-torsion free semiprime ring. In addition, we talk over above identities in the setting of *-ring(ring with involution).

• Bulletin of the Korean Mathematical Society
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• v.61 no.3
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• pp.813-823
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• 2024

In this paper, we prove that every 2-local derivation on several classes of C^*-algebras, such as unital properly infinite, type I or residually finite-dimensional C^*-algebras, is a derivation. We show that the following statements are equivalent: (1) every 2-local derivation on a C^*-algebra is a derivation, (2) every 2-local derivation on a unital primitive antiliminal and no properly infinite C^*-algebra is a derivation. We also show that every 2-local derivation on a group C^*-algebra C^*(𝔽) or a unital simple infinite-dimensional quasidiagonal C^*-algebra, which is stable finite antiliminal C^*-algebra, is a derivation.

• Journal of Korea Game Society
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• v.9 no.2
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• pp.3-12
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• 2009

In this study, by both qualitative and quantitative measurement on the purpose of deriving the sensitive amusement factor. I consider the fear of horror games as "the amused fear" and analyze it, which is based on the play theory by Roger Caillois. On the basis of this, I classified the amusement fear in horror games into the 4 factors. I conducted some positive tests through the player's response in order to verify them. The test is conducted measuring the heart rate of each experimenter by cardiometer while they are playing horror games. By analyzing the video data, I gave a name to the point that the amusement fear factors are expected to influence psychologically and physiologically as the fear point. At this point, I examined if the measured heart rate makes the outstanding difference or not, when compared average heart rate with experimenter's heart rate. In addition, I also examined if there is a statistical correlation of heart rate by attaching player's subjective data through the questionnaire. Consequently, it was statistically turned out that the experimenter's heart rate which is measured rose dramatically than usual, and that there are close correlations among subjective data. I also found out that the amusement fear factor at the relevant point plays a major role in experimenter's psychological and physiological response. In this study, I could prove the horror factor as a meaning of amusement factor using both theoretical method and positive method establishing a standard set that is helpful for further production and planning of the game.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.4
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• pp.1999-2006
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• 2016

Background: Acute promyelocytic leukemia (APML) is characterized by the reciprocal translocation t(15;17) (p22;p12) resulting in the PML-$RAR{\alpha}$ fusion gene. A dual diagnostic and follow up approach was applied including cytogenetic demonstration of the t(15;17) translocation and detection dg PML-$RAR{\alpha}$ chimeric transcripts by molecular means. Purpose: Conventional cytogenetics involving bone marrow is beset with high probability of poor metaphase index and was substituted with phytohemagglutinin (PHA)-induced peripheral blood culture based cytogenetic analysis as a diagnostic & follow up modality in APML patients of Kashmir (North India). Both qualitative (RT-PCR) and quantitative (Q-PCR) tests were simultaneously carried out to authenticte the modified cytogenetics. Materials and Method: Patient samples were subjected to the said techniques to establish their baseline as well as follow-up status. Results: Initial cytogenetics revealed 30 patients (81%) Positive for t(15;17) whereas 7 (19%) had either cryptic translocation or were negative for t(15;17). Two cases had chromosome 16q deletion and no hallmark translocation t(15;17). Q-PCR status for PML-$RAR{\alpha}$ was found to be positive for all patients. All the APML patients were reassessed at the end of consolidation phase and during maintenance phase of chemotherapy where 6 patients had molecular relapse, wherein 4 also demonstrated cytogenetic relapse. Conclusions: It was found that PHA-induced peripheral blood cytogenetics along with molecular analysis could prove a reliable modality in the diagnosis and assessment of follow up response of APML patients.

• Proceedings of the KIEE Conference
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• 2007.07a
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• pp.731-732
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• 2007

This paper presents the final configuration of test field and test items for the application of IEC 60364-4-44 in Korea. IEC 60364-4-44 provides rules for the protection against the effects of conducted and radiated disturbances on electrical installations. Especially this standard deals with the protection of low voltage facility against the ground fault in the high voltage side of power distribution system. Many countries define the regulations on the use of electrical facilities based on their own power system and technical references which are considered to be suitable for them. The background of circuit of IEC 60364-4-44 is based on the ungrounded system as most of European countries. However, domestic electric power distribution system is based on multi-grounding system different from European system. Therefore, it is necessary to evaluate or prove the effect of the IEC 60364-4-44 for introducing and applying it to the domestic grounding system as a national standard. The authors with KEA(Korea Electric Association) carried out a project on the application of IEC 60364-4-44 to Korean electrical installations of buildings sponsored by Korean ministry of commerce, industry and energy for three years(2004.4.1$\sim$2007.3.31). The test field is established in K.E.R.I.(Korea Electrotechnology Research Institute), which is the purpose of evaluating the formula to calculate touch voltage and stress voltage in the IEC standards. This paper presents some considerations and final configuration of test field to evaluate and introduce the IEC 60364-4-44 applicable to domestic rule for the protection against ground fault.

• Biomolecules & Therapeutics
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• v.18 no.2
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• pp.226-232
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• 2010

The aim of this study was to investigate the effect of atrovasatatin on the pharmacokinetics of nicardipine after oral and intravenous administration of nicardipine to rats. Nicardipine was administered orally (12 mg/kg) or intravenously (i.v., 4 mg/kg) without or with oral administration of atrovasatatin (0.3 or 1.0 mg/kg) to rats. The effect of atorvastatin on the P-glycoprotein (P-gp) as well as CYP3A4 activity was also evaluated. Atorvastatin inhibited CYP3A4 enzyme activity in a concentration-dependent manner with 50% inhibition concentration ($IC_{50}$) of 48 ${\mu}M$. Compared to the controls (nicardipine alone), the area under the plasma concentration-time curve (AUC) of nicardipine was significantly (1.0 mg/kg, p<0.05) greater by 16.8-45.4%, and the peak plasma concentration ($C_{max}$) was significantly (1.0 mg/kg, p<0.05) higher by 28.0% after oral administration of nicardipine with atorvastatin, respectively. Consequently, the relative bioavailability (R.B.) of nicardipine was increased by 1.17- to 1.45-fold and the absolute bioavailability (A.B.) of nicardipine with atrovasatatin was significantly greater by 16.7-20.9% compared to that of the controls (14.3%). Compared to the i.v. control, atrovasatatin did not significantly change pharmacokinetic parameters of i.v. administration nicardipine. The enhanced oral bioavailability of nicardipine by atorvastatin suggests that CYP3A subfamily-mediated metabolism were inhibited in the intestine and/or in the liver rather than P-gp-mediated efflux of nicardipine. Based on these results, modification of nicardipine of dosage regimen is required in the patients. Human studies are required to prove the above hypothesis.

• Kyungpook Mathematical Journal
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• v.13 no.2
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• pp.235-240
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• 1973

A k-dimensional vector bundle is a bundle ${\xi}=(E,P,B,F^k)$ with fibre $F^k$ satisfying the local triviality, where F is the field of real numbers R or complex numbers C ([1], [2] and [3]). Let $Vect_k(X)$ be the set consisting of all isomorphism classes of k-dimensional vector bundles over the topological space X. Then $Vect_F(X)=\{Vect_k(X)\}_{k=0,1,{\cdots}}$ is a semigroup with Whitney sum (${\S}1$). For a pair (X, A) of topological spaces, a difference isomorphism over (X, A) is a vector bundle morphism ([2], [3]) ${\alpha}:{\xi}_0{\rightarrow}{\xi}_1$ such that the restriction ${\alpha}:{\xi}_0{\mid}A{\longrightarrow}{\xi}_1{\mid}A$ is an isomorphism. Let $S_k(X,A)$ be the set of all difference isomorphism classes over (X, A) of k-dimensional vector bundles over X with fibre $F^k$. Then $S_F(X,A)=\{S_k(X,A)\}_{k=0,1,{\cdots}}$, is a semigroup with Whitney Sum (${\S}2$). In this paper, we shall prove a relation between $Vect_F(X)$ and $S_F(X,A)$ under some conditions (Theorem 2, which is the main theorem of this paper). We shall use the following theorem in the paper. THEOREM 1. Let ${\xi}=(E,P,B)$ be a locally trivial bundle with fibre F, where (B, A) is a relative CW-complex. Then all cross sections S of ${\xi}{\mid}A$ prolong to a cross section $S^*$ of ${\xi}$ under either of the following hypothesis: (H1) The space F is (m-1)-connected for each $m{\leq}dim$ B. (H2) There is a relative CW-complex (Y, X) such that $B=Y{\times}I$ and $A=(X{\times}I)$ ${\cap}(Y{\times}O)$, where I=[0, 1]. (For proof see p.21 [2]).

• Journal of Microbiology and Biotechnology
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• v.28 no.1
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• pp.122-135
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• 2018

Listeriolysin O (LLO), one of the most immunogenic proteins of Listeria monocytogenes and its main virulence factor, mediates bacterial escape from the phagosome of the infected cell. Thus, its expression in a nonpathogenic bacterial host may enable effective delivery of heterologous antigens to the host cell cytosol and lead to their processing predominantly through the cytosolic MHC class I presentation pathway. The aim of this project was to characterize the delivery of a model antigen, chicken egg ovalbumin (OVA), to the cytosol of dendritic cells by recombinant Bacillus subtilis vegetative cells expressing LLO. Our work indicated that LLO produced by non-sporulating vegetative bacteria was able to support OVA epitope presentation by MHC I molecules on the surface of antigen presenting cells and consequently influence OVA-specific cytotoxic T cell activation. Additionally, it was proven that the genetic context of the epitope sequence is of great importance, as only the native full-sequence OVA fused to the N-terminal fragment of LLO was sufficient for effective epitope delivery and activation of $CD8^+$ lymphocytes. These results demonstrate the necessity for further verification of the fusion antigen potency of enhancing the MHC I presentation, and they prove that LLO-producing B. subtilis may represent a novel and attractive candidate for a vaccine vector.

• Journal of the Korean Society for Library and Information Science
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• v.15
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• pp.141-173
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• 1988

The focuses and methods in Library science have been changed abreast with the development af library facilities and with the expansion and diversification of its functions. One of current trends in Library science is focussed on the social functions of library: its relations to the public, effective service for the users. and efficieniencies of the management policies, and so. on. To. deal with these issues, we need to borrow methodology from other disciplines such as management, marketing, statistics, etc. This paper is mainly concerned with how we approach to the measurement af services and thus provide tentative standard for evaluating library services. To do. this work properly, we'd better consider the users' needs and expectations. But it is not an easy work since too many factors are involved in the study of the users' needs. Users' needs and expectations are so. varying that it is difficult to find out some general and objective data. That is the reason why although many scholars have urged time after time the necessity of library's effectiveness measurement, few studies demonstrated substantial method for measuring the effectiveness of service. In this paper I propose a device for measuring service: i. e, Conjoint Analysis. Conjoint Analysis, which has originally been developed and applied in marketing research, is used to measure the priorities and preferences of purchasers on the new item. So far as Conjoint Analysis, concerning users' physical and psychological necessities, can numeralize people's needs, it may also be applied to measure service provided by nonprofit organization like library. If this approach prove to be sucessful, I hope this study to make any contribution to the appropriate direction on improving library facilities based on the result from a concret reference evaluation.