• Korean Journal of Acupuncture
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• v.29 no.3
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• pp.431-440
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• 2012

Objectives : Recently, network science is very popular topic in various scientific fields and many studies have reported that it gives meaningful results on studying characteristics of a complex system. In this study, based on network theory, we made acupoints network using data of combined acupoints which appeared at "Beijiqianjinyaofang". We focused to find out the distinctive roles of remote and local combinations on the network. Furthermore, we aimed to identify the possibility of numerical and quantitative application to acupuncture researches. Methods : Based on examples of combined acupoints in "Beijiqianjinyaofang", the network consisted of 291 nodes and 2,431 links. The spatial distances between combined acupoints were calculated by the human dummy model. We removed the links step by step for the three cases - remote, local, and random cases, and observed the characteristic changes by calculating path lengths, similarity indices, and clustering coefficients. Also cluster analysis was carried out. Results : The network had a small number of remote links, and a large number of local links. These two links had the distinct characteristics. Whereas the local links formed a cluster of nearby nodes, remote links played a role to increase the correlation between the clusters. Conclusions : These results suggest that acupoints network increases the connectivity between the distal part and the trunk of human body, and enables various combinations of the acupoints. This finding conclusively showed that mechanism of combined acupoints could be interpreted meaningfully by applying network theory in acupuncture researches.

• Korean Journal of Human Ecology
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• v.15 no.6
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• pp.919-935
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• 2006

The purpose of this study was to analyze the relationship between outdoor play environments and child's play behaviors. The data were collected by field measurement survey, and non-participatory observation from 9 child care centers in Daejeon. The field measurement survey were conducted from June 20 to July 20, 2004, whereas non-participatory behavior observation were conducted from September 2 to October 10, 2004. The major results showed the following. 1) The characteristics of outdoor play environment in child care centers showed that most of them were too small and did not use the adequate surfacing to play various activities. In many cases, outdoor play settings was made of play equipment setting, play props and manipulative settings, and tree/vegetation. 2) Child's play behavior has been focused on functional play activity and construction play activity. 3) The relationship between outdoor play environments and child's play behaviors showed that small outside play environment with monotonous construction and multi-complex play equipments produced functional play behaviors on children. On the other hand, where various play areas were put together, we could observe relatively diverse play behaviors. However, in some cases, despite the small and monotonous play area, diverse play behaviors were observed. These playgrounds at least differed from others in that they provided the place where multi purpose play was possible. This finding shows that multi purpose play areas can be an alternative in small playground environment.

• Fashion & Textile Research Journal
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• v.19 no.3
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• pp.296-301
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• 2017

This study researched the status and prospect of a natural dye program in Gyeongsang region that focused on private centers with sufficient infrastructure and abundant human resources were available for natural dyes. The entire site for metropolitan cities that have difficulty in securing the land are limited (as well as smaller) because they are closer to the city; in addition, they do not own the drying house and the agricultural land for natural dyes. It is understood that the one-time program of all centers researched help to promote and maintain the centers rather than generating profit; in addition, it is shown that Jun - Aug (summer) is preferred over Dec - Feb (winter). This program uses natural indigo; consequently, natural dye program for hobby and education is operated when it is required because the number of participants are low in most cases, Persimmon Juice is used for the dyeing raw materials. Programs in operation are often outsourced with other institutes registered under private certification system; therefore, many cases of starting business are found in the institutes operating programs directly after obtaining the certification. Their plans do not allow for investment in facility such as enlargement of experience center and prospect of program; in addition, business value is generally bright for business strategies that include an exhibition shop for natural dye products and program development.

• Korean Journal of Human Ecology
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• v.22 no.1
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• pp.167-179
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• 2013

In recent years, Corporate Social Responsibility (CSR) has received particular attentions from both practitioners and scholars. This study focused on Korean national fashion businesses and identified various types of CSR practices in addition to social contributions. Besides, comparison in corporation by size of the number of full-time employees and sales volume were examined. A total of 1054 cases of 147 brands, 86 corporations between 2000 and 2012 were collected from internet articles and brand home pages. Findings were as follows. First, the types of CSR activities were categorized into the following six: economic responsibility, legal responsibility, consumer protection, protection of worker's right, protection of environment, and social contribution. Social contribution took largest portion of CSR activities (67.7%), followed by environmental protection (14%), and protection of worker's right (6.2%). The other three types presented limited cases but included negative aspects of CSR. Social contribution consisted of six sub categories (culture & art, sports, education, donation, voluntary service, and campaign), and donation took the largest part of social contribution area. Second, comparing 86 corporations by the size of the number of full-time employees, companies more than 300 employees (38.1%) were more likely to practice CSR activities. Similarly, companies with more than 500 billion won sales (13.1%) were more active in their CSR activities than their counterparts. Suggestions are given for improving CSR practices to fashion business.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.11
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• pp.6961-6964
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• 2013

Human papillomavirus (HPV) is a major cause of cervical cancer. More than 100 HPV genotypes have been identified; however the distribution varies geographically and according to ethnicity. The purpose of this study was to investigate the prevalence and distribution of HPV subtypes among Northeast Thai women. Subjects included 198 cases of SCCA and 198 age-matched, healthy controls. HPV-DNA was amplified by PCR using the consensus primers GP5+/6+ system followed by reverse line blot hybridization genotyping. The prevalence of high-risk HPV infection was 21 (10.1%) and 152 (76.8%) in the controls and in the cases, respectively. High-risk HPV significantly increased the risk for cervical cancer with an OR of 42.4 (95%CI: 22.4-81.4, p<0.001) and an adjusted OR of 40.7-fold (95%CI: 21.5-76.8, p <0.001). HPV-16 was the most prevalent HPV type in the SCCA (56.2%) followed by HPV-58 (17.8%) and HPV-18 (13.6%); whereas HPV-58 (46.4%) was a prominent genotype in the controls followed by HPV-16 (39.3%) and unidentified HPV types (25.0%). These findings indicate that HPV infection remains a critical risk factor for SCCA; particularly, HPV-16, HPV-58 and HPV-18. In order to eradicate cervical cancer, sustained health education, promoted use of prophylactics and a HPV-58 vaccine should be introduced in this region.

• Journal of the Korean Society of Costume
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• v.62 no.6
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• pp.19-37
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• 2012

This study was done to define the color range, images and color characteristics of beige in fashion by analyzing the characteristics of beige that appears in contemporary fashion. In reference research, the general characteristics, the color name and range of beige was examined. In investigation research, color characteristics and images of beige that appear in contemporary fashion was defined, and it was discovered that the cases that the use of beige took more than 50% of the entire in the major collection from S/S season in 2007 to F/W season in 2010 as the subject of color analysis. The result of the study could be summarized as follows: First, the color range of beige consisted of the standard color from 2.5YR to 5YR, and color tone was pale and light gray. Second, the analysis of color beige that appear in contemporary fashion didn't show big differences according to year, season, and region. The color tones consisted of light grayish, pale, light, soft focusing colors from 5YR to 10YR. As for the arrangement of colors, it was arranged with black and it was used with the affiliation of YR, R, Y in many cases. Third, beige monochromatic image appeared soft, plain and classic. The arrangement of the image, modern, feminine, luxurious, gentle, intelligent five types were derived. Arrangements with achromatic colors were expressed in contemporary and sophisticated styles and arrangements with chromatic colors appeared to be soft, feminine and luxurious. This study draws the result to apply the fashion image of beige that was insufficient in other various color researches to design various color aspects by defining the image of beige that appears in contemporary fashion. Based on practical analysis for the color beige, it is evident that beige is an important factor and a powerful influence on fashion images.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.4
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• pp.1443-1448
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• 2015

To investigate the significance of FOXO3a and Ki67 in human lung adenocarcinomas. Envision immunohistochemical staining and Western blotting were used to examine the protein expression of FOXO3a in 127 cases of human lung adenocarcinoma specimens. The positive rate in lung adenocarcinoma (55.9%) was lower than that in normal tissues (80%). We found that the expression of FOXO3a was closely related with the degree of differentiation, TNM staging, lymph node metastasis and survival. In addition, significant differences in the different pathological types of lung adenocarcinoma cases (P<0.01). The FOXO3a positive rate of the acini as the main type (APA) (86.7%) and the lepidic as the main type (LPA) (82.4%) was higher than the solid as the main type (SPA) (50.0%), the papilla as the main type (PPA) (42.9%) and the micropapilla as the main type (MPA) (9.4%). Moreover, the expression of FOXO3a was negatively related with Ki67 expression. Our results suggested that the expression of FOXO3a is closely correlated with the aggressiveness of lung adenocarcinoma. It was indicated that disregulation of FOXO3a might play key roles in the occurrence and development of lung a denocarcinoma and joint detection of the two markers might play an important role in diagnosing tumors.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.14
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• pp.5819-5823
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• 2014

Purpose: To investigate the expression of hypoxia-inducible factor prolyl hydroxylase 3 (HIFPH3) in non-small cell lung cancer (NSCLC) and explore the correlation of HIFPH3 expression with lymph node metastasis and microvessel density (MVD). Materials and Methods: A total of 73 cases of NSCLC specimens, 24 cases of para-cancerous tissues, and 20 normal pulmonary tissues were collected for HIFPH3 and CD31 immunohistochmical (IHC) study. Microvessel density (MVD) of the NSCLC tissues was also determined based on the expression of CD31. Results: The expression of HIFPH3 in carcinoma tissue was statistically higher than para-cancerous and normal pulmonary tissues (${\chi}^2=48.806$, p<0.05). Compared withthe negative lymph node metastasis group, the lymph node metastasis group showed significantly higher HIFPH3 expression (${\chi}^2=6.300$, p<0.05). The strong HIFPH3+group displayed a significantly higher MVD than weak HIFPH3+ and HIFPH3- groups (p<0.05). No differences in positive HIFPH3 expression were noted regarding the tumor diameter, age, smoking status, gender of NSCLC patients, tumor size, histopathology, or differentiation. Conclusions: HIFPH3 expression in human NSCLC lesions is significantly higher than that in para-cancerous and normal lung tissues and is positively associated with lymph node metastasis and MVD.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.36 no.1
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• pp.25-29
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• 2014

The purpose of this study is to report on five cases treated with bone graft using recombinant human bone morphogenetic protein-2 (rhBMP-2) on jaw defects after cyst enucleation. We performed bone graft with BMP (rhBMP-2+${\beta}$-tricalcium phosphate/hydroxyapatite) wrapped with a collagen sponge on jaw defects after cyst enucleation. Postoperative panoramic radiographs were taken periodically. After 1 to 12 months, bone remodeling was observed in the jaw defect area. In our cases, there were few signs or symptoms of recurrence of the cyst during the follow-up period.

• Clinical and Experimental Pediatrics
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• v.61 no.6
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• pp.180-186
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• 2018

Purpose: Despite the availability of molecular methods, identification of the causative virus in children with acute respiratory infections (ARIs) has proven difficult as the same viruses are often detected in asymptomatic children. Methods: Multiplex reverse transcription polymerase chain reaction assays were performed to detect 15 common respiratory viruses in children under 15 years of age who were hospitalized with ARI between January 2013 and December 2015. Viral epidemiology and clinical profiles of single virus infections were evaluated. Results: Of 3,505 patients, viruses were identified in 2,424 (69.1%), with the assay revealing a single virus in 1,747 cases (49.8%). While major pathogens in single virus-positive cases differed according to age, human rhinovirus (hRV) was common in patients of all ages. Respiratory syncytial virus (RSV), influenza virus (IF), and human metapneumovirus (hMPV) were found to be seasonal pathogens, appearing from fall through winter and spring, whereas hRV and adenovirus (AdV) were detected in every season. Patients with ARIs caused by RSV and hRV were frequently afebrile and more commonly had wheezing compared with patients with other viral ARIs. Neutrophil-dominant inflammation was observed in ARIs caused by IF, AdV, and hRV, whereas lymphocyte-dominant inflammation was observed with RSV A, parainfluenza virus, and hMPV. Monocytosis was common with RSV and AdV, whereas eosinophilia was observed with hRV. Conclusion: In combination with viral identification, recognition of virus-specific clinical and laboratory patterns will expand our understanding of the epidemiology of viral ARIs and help us to establish more efficient therapeutic and preventive strategies.