• Development and Reproduction
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• v.1 no.1
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• pp.25-28
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• 1997

The present study was conducted to determine the effect of recombinant human follicle stimulating hormone (rhFSH) on the estrogen synthesis by human fetal ovarian tissues. Fetal ovaries were 18-19 weeks old (18 wks:n=1, 19 wks:n=2). One case of 19-week-old fetal ovaries were obtained from anencephalic fetus. Obtained ovarieswere cleaned and diced around $600\mu\textrm{m}$ pieces, and cultured in the sandwich agar bed system for 21-23 days. Estrone ($E_{1}$) and estradiol-17 $\beta$($E_{2}$) in the medium was measured by radioimmunoassay. Amount of $E_{2}$ synthesis was greater than $E_{1}$ in both normal cases. In contrast, fetal ovaries from anencephalic fetus did not produce neither $E_{1}$ nor $E_{2}$ in the presence or absence of rhFSH. Results suggest that the fetal ovaries have a capacity of estrogen production at 18-19 weeks of gestation Existence of FSH receptor is also supposed. Different results by anecephalic fetal ovaries suggest the difference in the development between normal and anencephalic fetal ovaries.

• Journal of the Korean Society of Safety
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• v.25 no.3
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• pp.123-130
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• 2010

Electroencephalogram(EEG) would be the most objective psychophysiological research technique on human errors though few research has been taken yet. This study aimed to get characteristics of human error while committing simple Odd-Ball tasks by utilizing the power spectrum technique of EEG data. Each experiment was composed of 3 tasks with different rules, and 8 young undergraduate students participated in this study as paid subjects. The result showed in the affirmative that subject and the interaction of subject and task factors were statistically significant on variation of $\alpha$ band power $P_{\alpha/(\alpha+\beta+\theta)}$ and $\beta$ band power $P_{\beta/(\alpha+\beta+\theta)}$, and that the former increasing in backward direction to Pz reflects compatibility whereas the latter increasing in forward direction to Fz reflects familiarity. Therefore it was coucluded that, since task 2 carried out in the present research requiring decoding process would be more difficult to human beings than the task merely requiring psychological recall process, task 1 and task 3 were classified into a homogenious group excluding task 2, and the ratio $\alpha$ band power to $\beta$ band power indicated enormous increase of $\alpha$ band power relative to $\beta$ band power in the cases of contra-lateral errors, especially in task 2.

• Safety and Health at Work
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• v.7 no.3
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• pp.194-200
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• 2016

Background: The influence of sociocultural factors on human reliability within an open sociotechnical systems is highlighted. The design of such systems is enhanced by experience feedback. Methods: The study was focused on a survey related to the observation of working cases, and by processing of incident/accident statistics and semistructured interviews in the qualitative part. In order to consolidate the study approach, we considered a schedule for the purpose of standard statistical measurements. We tried to be unbiased by supporting an exhaustive list of all worker categories including age, sex, educational level, prescribed task, accountability level, etc. The survey was reinforced by a schedule distributed to 300 workers belonging to two oil companies. This schedule comprises 30 items related to six main factors that influence human reliability. Results: Qualitative observations and schedule data processing had shown that the sociocultural factors can negatively and positively influence operator behaviors. Conclusion: The explored sociocultural factors influence the human reliability both in qualitative and quantitative manners. The proposed model shows how reliability can be enhanced by some measures such as experience feedback based on, for example, safety improvements, training, and information. With that is added the continuous systems improvements to improve sociocultural reality and to reduce negative behaviors.

• Journal of Korean Biological Nursing Science
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• v.10 no.2
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• pp.131-140
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• 2008

Purpose: This study is about safety of the expressed human milk by investigating its bacterial contamination and antibiotic resistance of the microbes in the expressed milk. Methods: The data are collected from the 156 mothers and their newborn infants in NICU of U University Hospital from January 2004 to September 2005. Results: 1) The expressed human milk was contaminated by Staphylococcus epidermidis for 66.7%, Two mixed bacterial strain for 11.5%, Acinetobacter species for 8.0%, Klebsiella species for 4.6%, Staphylococcus aureus for 4.6%. 2) The microbes in the human milk had high resistance to the Antimicrobial agents: 77.5% for Penicillin-G, 66.6% for Oxacillin, and 63.7% for Cephalothin. 3) The distribution of microbes showed a significant depending on the place of the milk expression (p=.020). In particular, mixed bacterial strain was found more in the milks expressed at home than the milk expressed at the hospital. Conclusion: This study shows the importance of systematic education of feeding process in expressed milk: poor management of a breast pump, inadequate hand washing and imperfect breast cleaning explain the reasons of contamination 156 cases.

• Clinical and Experimental Pediatrics
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• v.52 no.3
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• pp.269-276
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• 2009

Viruses are the most common cause of lower respiratory tract infections (LRTIs) in infants and young children and are a major public health problem in this age group. Viruses were identified in 54.9-70.4% of hospitalized infants and children with LRTIs in Korea. The viral pathogens identified included respiratory syncytial virus (RSV) A and RSV B, influenza (Inf) A, Inf B, parainfluenza (PIV)1, PIV2, human bocavirus (hBoV), human rhinovirus (hRV), adenovirus (ADV), human metapneumovirus (hMPV), human coronavirus (hCoV)-OC 43, hCoV-229E, hCoV-NL63, hCoV-HKU1, and human enterovirus (hEV). Coinfections with ${\geq}$2 viruses were observed in 11.5-22.8% of children. The occurrence of LRTIs was the highest in the first year of life. The specific viruses are frequently associated with specific clinical syndromes of LRTIs. LRTIs caused by RSV were predominant among younger infants. hRV accounted for a larger proportion of LRTIs in young infants than ADV and hBoV. hMPV was frequently detected in children >24 months old. The number of hMPV infections peaked between February and May, whereas hRV was detected throughout the year. Thus far, hCoV is a less common respiratory pathogen in cases of ALRI and URI in Korean children.

• Clinics in Shoulder and Elbow
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• v.19 no.2
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• pp.84-89
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• 2016

Background: The purpose of this study was to assess the results of arthroscopic bridging repair using a human dermis allograft in the treatment of massive irreparable rotator cuff tears. Methods: From November 2009 to April 2011, 12 patients underwent arthroscopic bridging repair using a human dermis allograft in the treatment of massive irreparable rotator cuff tears. Patients were followed for an average of 33.9 months. Clinical outcome was evaluated preoperatively and postoperatively using the mean University of California, Los Angeles (UCLA) score and the Korean Shoulder Scoring System (KSS). Magnetic resonance imaging (MRI) was performed postoperatively at an average of 6.5 months. Results: At a mean follow-up of 33.9 months (range, 25 to 42 months), 11 out of 12 patients were satisfied with their procedure. Patients showed significant improvement in their mean modified UCLA score from 15.9 preoperatively to 29.4 postoperatively (p=0.001). The mean KSS score improved from 45.6 preoperatively to 80.5 postoperatively (p=0.002). In MRI studies, 9 out of 12 patients had full incorporation of the graft into the native rotator cuff remnant. To date, there has been no intraoperative or postoperative complication from the graft procedure, such as infection or allograft rejection, in any patient. Conclusions: Arthroscopic bridging repair using a human dermis allograft can be considered as an option in treatment of select cases of massive irreparable rotator cuff tears, resulting in high patient satisfaction.

• Journal of The Korean Digital Architecture Interior Association
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• v.10 no.1
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• pp.15-22
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• 2010

As for structural system, which constitutes his construction, there are column inside dimension and span which constitutes plane, and as for constructions for section, there are C.H and slab, and as for constructive factors for envelope, there are window and closing panel of outer wall, and as for opening, there are punching window and wave window. With these constructive parts and opening of envelope, his construction composes volume and mass. The relation of structure and modulor which are shown in his later construction can be divided in two cases that modulor is directly and indirectly adapted for rate and measure calculation of the constructive body. As for indirectly adapted case, we can find it form most of his later construction, it is living place in which human beings life is, and it is adapted mainly for small space. In his construction, he tried to tell human scale and sense of musical rhythm through modulor. In other words, he played sense of space and musical scale by adapting regular and repetitive modulor of opening, and in small space for daily life, he made the size of space into the space which human can perceive. And, if we interpret mudulor in modern meaning, it is an establishment of radius of human act. And, we can make organic and harmonic design of space if we use modulor as origin of human centered measurement calculation, and if we adapt space after dividing by use.

• The Journal of Korean Obstetrics and Gynecology
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• v.32 no.1
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• pp.94-107
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• 2019

Purpose: To report the effect of Traditional Korean medical treatments on 5 patients with cervical intraepithelial neoplasia with high-risk human papilloma virus (HPV). Methods: The patients were diagnosed with cervical intraepithelial neoplasia with High-Risk human papilloma virus. The patients were treated by Traditional Korean Medicine such as herb medication and fumigation therapy. Results: After 3~6 months treatments, cervical intraepithelial neoplasia grades 1-2 lesions regressed and high-risk HPV infections were not detected. Conclusions: The case report shows that Korean medical treatment can be an effective option for treating lower grade of cervical intraepithelial neoplasia with high-risk human papilloma virus.

• Journal of Microbiology and Biotechnology
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• v.33 no.8
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• pp.981-991
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• 2023

Monkeypox (Mpox) virus, a member of the Poxviridae family, causes a severe illness similar to smallpox, which is characterized by symptoms such as high fever, rash, and pustules. Human-to-human transmission cases have been reported but remained low since the first recorded case of human infection occurred in the Congo in 1970. Recently, Mpox has re-emerged, leading to an alarming surge in infections worldwide since 2022, originating in the United Kingdom. Consequently, the World Health Organization (WHO) officially declared the '2022-23 Mpox outbreak'. Currently, no specific therapy or vaccine is available for Mpox. Therefore, patients infected with Mpox are treated using conventional therapies developed for smallpox. However, the vaccines developed for smallpox have demonstrated only partial efficacy against Mpox, allowing viral transmission among humans. In this review, we discuss the current epidemiology of the ongoing Mpox outbreak and provide an update on the progress made in diagnosis, treatment, and development of vaccines for Mpox.

• Journal of applied mathematics & informatics
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• v.32 no.5_6
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• pp.649-663
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• 2014

Presence of eyelid on anterior ocular surface and its thermal effects play significant role in maintaining eye temperature. In most of the literatures of thermal modeling in human eye, the eyelid is not considered as an eye component. In this paper, finite element model is developed to investigate the thermal effects of eyelid closure and opening in human eye. Based on different properties and parameter values reported in literatures, the bio-heat transfer process is simulated and compared with experimental results in steady and transient state cases. The sensitivity analysis using various ambient temperatures, evaporation rates, blood temperatures and lens thermal conductivities is carried out. The temperature values so obtained in open eye show a good agreement with past results. The closure of eyelid is found to increase/decrease the eye temperature significantly than its opening, when the parameter values are considered to be at extreme.