• 제목/요약/키워드: high-dose

검색결과 4,293건 처리시간 0.032초

칼라 CCD 영상을 이용한 고휘도 LED 전구의 빔 열화 분석 (Analysis of High Luminance LED Beam Degradation using Color CCD Image)

  • 조재완;최영수;이재철;구인수;홍석붕
    • 제어로봇시스템학회논문지
    • /
    • 제16권6호
    • /
    • pp.586-591
    • /
    • 2010
  • VLC (Visible Light Communication) is a wireless communication method using light that is visible to the human eye. It has a major advantage that it causes no interference to RF-based devices. This makes wireless communication possible in RF hazardous areas such as nuclear facilities. In order to apply VLC communication in harsh environment of nuclear power plant, the high luminance LEDs, which are key components of the VLC communication, have been gamma-ray irradiated at the dose rate of 4kGy/h during 72 hours up to a total dose of 288 kGy. The radiation induced color-center was formed in the LED housing cap made of transparent plastic or acryl material. The beam degradations of high luminance LEDs by high dose-rate gammaray irradiation are analyzed using color CCD image processing technology.

Effect of Platycodon Grandiflorum Aqueous Extract on Lipid Levels in Rats

  • Kim Jeong-Seon
    • Nutritional Sciences
    • /
    • 제9권3호
    • /
    • pp.167-172
    • /
    • 2006
  • This study investigated the effects of Platycodon grandiflorum aqueous extract on lipid concentration of serum and liver in rats fed high cholesterol diet Male Sprague-Dawley rats were assigned to three groups (control, low dose of extract, high dose of extract) for four weeks. The serum total cholesterol concentration was significantly lower in the low and high doses of extract groups than in the control group. There was a significant decrease in the free cholesterol, cholesterol ester, LDL-cholesterol, and triglycerides concentrations in serum, and the total cholesterol and the triglycerides contentin liver in the low and high doses of extract groups compared to the control group. When the serum phospholipid concentration was compared among the groups, it was significantly lower in high dose of extract group than in control and low dose of extract group. It can be postulated that Platycodon grandiflorum aqueous extract may possess substantial hypolipidemic properties in rats.

Real-time monitoring of ultra-high dose rate electron beams using bremsstrahlung photons

  • Hyun Kim;Dong Hyeok Jeong;Sang Koo Kang;Manwoo Lee;Heuijin Lim;Sang Jin Lee;Kyoung Won Jang
    • Nuclear Engineering and Technology
    • /
    • 제55권9호
    • /
    • pp.3417-3422
    • /
    • 2023
  • Recently, as the clinically positive biological effects of ultra-high dose rate (UHDR) radiation beams have been revealed, interest in flash radiation therapy has increased. Generally, FLASH preclinical experiments are performed using UHDR electron beams generated by linear accelerators. Real-time monitoring of UHDR beams is required to deliver the correct dose to a sample. However, it is difficult to use typical transmission-type ionization chambers for primary beam monitoring because there is no suitable electrometer capable of reading high pulsed currents, and collection efficiency is drastically reduced in pulsed radiation beams with ultra-high doses. In this study, a monitoring method using bremsstrahlung photons generated by irradiation devices and a water phantom was proposed. Charges collected in an ionization chamber located at the back of a water phantom were analyzed using the bremsstrahlung tail on electron depth dose curves obtained using radiochromic films. The dose conversion factor for converting a monitored charge into a delivered dose was determined analytically for the Advanced Markus® chamber and compared with experimentally determined values. It is anticipated that the method proposed in this study can be useful for monitoring sample doses in UHDR electron beam irradiation.

Effects of Exposure to Estradiol Benzoate or Flutamide at the Weaning Age on Expression of Connexins in the Caudal Epididymis of Adult Rat

  • Lee, Ki-Ho
    • 한국발생생물학회지:발생과생식
    • /
    • 제20권4호
    • /
    • pp.349-357
    • /
    • 2016
  • The present research was chiefly designed to determine the effect of the treatment of estrogenic agonist, estradiol benzoate (EB), or antiandrogenic compound, flutamide (Flu), at the weaning age on the expression of connexin (Cx) isoforms in the caudal epididymis of adult male rat. Animals were subcutaneously administrated with a single shot of either EB at a low-dose ($0.015{\mu}g$ of EB/kg body weight (BW)) or a high-dose ($1.5{\mu}g$ of EB/kg BW) or Flu at a low-dose ($500{\mu}g$ of EB/kg BW) or a high-dose (5 mg of EB/kg BW). Expressional changes of Cx isoforms in the adult caudal epididymis were examined by quantitative real-time PCR analysis. The treatment of a low-dose EB caused significant increases of Cx30.3, Cx31, Cx32, and Cx43 transcript levels but reduction of Cx31.1, Cx37, and Cx45 expression. Exposure to a high-dose EB resulted in very close responses observed in a low-dose EB treatment, except no significant expressional change of Cx37 and a significant induction of Cx40. Expression of all Cx isoforms, except Cx45, was significantly increased by a low-dose Flu treatment. Expressional increases of all Cx isoforms were detected by a high-dose Flu treatment. The current study demonstrates that a single exposure to estrogenic or antiandrogenic compound during the early postnatal developmental period is sufficient to disrupt normal expression of Cx isoforms in the adult caudal epididymis.

X-선 장치의 기술적 인자의 변화에 따른 선량 비교 평가 (A Comparison of Dose in Changed Technique Factor Using X-ray Imaging System)

  • 한동균;고신관;선종률;윤석환;정재은
    • 대한디지털의료영상학회논문지
    • /
    • 제11권2호
    • /
    • pp.101-107
    • /
    • 2009
  • With the recent development of diagnosis using radiation and increasing demand of the medical treatment, we need to minimize radiation exposure dose. So, This is the method which reduce patient dose by measuring surface dose of radiographic change factor and by comparing theoretical and actual dose, when we take an X-ray which is generally used. By changing the factor of kV, mAs, FSD, whose range is 60 to 120 kV, 20 to 100 mAs, 80 to 180 cm, we compared theoretical surface dose with actual surface dose calculated by the simple calculation program, Bit system, and NDD-M method As a result, when kV and mAs were higher, theoretical surface dose and actual surface dose were more increased. but the higher FSD was, the more decreased surface dose was. According to this, the error were measured about 0.1 to 0.2 mGy in low dose part and about 0.7 to 1.5 mGy in high dose part. Therefore, this shows that theoretical surface dose calculation method is more correct in low dose part than in high dose part. In conclusion, we will have to make constant efforts which can reduce patient and radiographer's exposure dose, studying methods which can predict patient's radiation exposure dose more exactly.

  • PDF

전자빔 가속기에 의한 페놀의 분해 I - 페놀의 분해와 생물학적 처리의 가능성 연구 - (Decomposition of Phenol by Electron Beam Accelerator I - Degree of Decomposition of Phenol and Possiblity of Biological Treatment -)

  • 양해영
    • 한국산업융합학회 논문집
    • /
    • 제15권3호
    • /
    • pp.71-77
    • /
    • 2012
  • This study gives the optimal reaction conditions, reaction mechanisms, reaction rates leaded from the oxidation of phenol by electron beam accelerator and ozone used for recent water treatment. It gives the new possibility of water treatment process to effectively manage industrial sewage containing toxic organic compounds and biological refractory materials. The high decomposition of phenol was observed at the low dose rate, but at this low dose rate, the reaction time was lengthened. So we must find out the optimal dose rate to promote high oxidation of reactants. The reason why the TOC value of aqueous solution wasn't decreased at the low dose was that there were a lot of low molecular organic acids as an intermediates such as formic acid or glyoxalic acid. In order to use both electron beam accelerator and biological treatment for high concentration refractory organic compounds, biological treatment is needed when low molecular organic compounds exist abundantly in sewage. In this experiment, the condition of making a lot of organic acids is from 5 kGy into 20 kGy dose. Decomposition rate of phenol by electron beam accelerator was first order reaction up to 300ppm phenol solution on the basic of TOC value and also showed first order reaction by using both air and ozone as an oxidants.

고(高) 에너지 전자선(電子線) 치료시(治療時) 체내(體內) 공동(空洞)으로 인(因)한 선량분포(線量分布)의 변동(變動) (Perturbation of Dose Distributions for Air Cavities in Tissue by High Energy Electron)

  • 추성실;이도행;최병숙
    • Journal of Radiation Protection and Research
    • /
    • 제1권1호
    • /
    • pp.22-30
    • /
    • 1976
  • The perturbation of dose distribution adjacent to cavities in high energy electron has shown that the percentage of dose increase varies markedly as a function of the build-up layer, the length and thickness of the cavities, and the electron energy. The dose distribution showed that cavities similar in size to those encountered in the head and neck measured by industrial film dosimetry and corrected by ionization chambers. The most increased doses by measuring are resulted in a localized dose of up to 130% of that measured at the depth of maximum dose within a homogeneous tissue equivalent phantom. The measured values and correction factors of dose perturbation due to air cavities showed in diagrams and would be summarized as follows. 1. In $8{\sim}12MeV$ electron beams, the most marked dose is observed when the build-up layer thickness is 0.5cm and cavity volume is $2{\times}2{\times}2cm^3$. 2. The highest dose point is located under cavity when the energy is increased and cavity length is longer. 3. The cavity length at which the maximum percentage dose occurs decreases with increasing energy. 4. The highest percentage cavity doses are obtained when the energy is high, the build-up layer is thin, the thickness of the cavity is large, and the length of the cavity is approximately 1 to 3cm. 5. The doses of upper portion of cavity are less than the standard dose distribution as 5 to 10%. 6. The maximum range of electron beam are extended as much as thickness of cavity. 7. A cavity having a length of 5cm closely approximates a cavity of infinite length.

  • PDF

Average Glandular Dose In Mammography

  • Kim, K.H.;Ryu, Y.C.;Oh, C.H.
    • 대한전기학회:학술대회논문집
    • /
    • 대한전기학회 2004년도 학술대회 논문집 정보 및 제어부문
    • /
    • pp.319-321
    • /
    • 2004
  • The average glandular dose (AGD) is determined by the breast entrance skin exposure, x-ray tube target material, beam quality (half-value layer), breast thickness, and breast composition. Almost breast cancer always arises in glandular breast tissue. As a result, the average radiation absorbed dose to glandular tissue is the preferred measure of the radiation risk associated with mammography. If the normalized average glandular dose is known, the average glandular dose can be computed from the product of the normalized average glandular dose and breast entrance skin exposure. In this study, AGD was calculated by the breast thickness and various x-ray energy (HVL) in 50% glandular 50% adipose breast by Mo.-Rh. assembly. AGD is 84 mrad in compressed 5 cm breast. These results show that as increasing the breast thickness, dose also increases. But as increasing the x-ray tube voltage, dose decreases because of high penetrating ratio through the object. But high tube voltage is reducing the subject contrast. From this result, we have to consider the trade-off between subject contrast of image and dose to the patient and choose proper x-ray energy range.

  • PDF

저선량 방사선 노출과 건강 영향에 대한 역학적 고찰 (Epidemiology of Low-Dose Ionizing Radiation Exposure and Health Effects)

  • 이원진
    • 한국환경보건학회지
    • /
    • 제49권1호
    • /
    • pp.1-10
    • /
    • 2023
  • Low-dose radiation exposure has received considerable attention because it reflects the general public's type and level of exposure. Still, controversy remains due to the relatively unclear results and uncertainty in risk estimation compared to high-dose radiation. However, recent epidemiological studies report direct evidence of health effects for various types of low-dose radiation exposure. In particular, international nuclear workers' studies, CT exposure studies, and children's cancer studies on natural radiation showed significantly increased cancer risk among the study populations despite their low-dose radiation exposure. These studies showed similar results even when the cumulative radiation dose was limited to an exposure group of less than 100 mGy, demonstrating that the observed excess risk was not affected by high exposure. A linear dose-response relationship between radiation exposure and cancer incidence has been observed, even at the low-dose interval. These recent epidemiological studies include relatively large populations, and findings are broadly consistent with previous studies on Japanese atomic bomb survivors. However, the health effects of low-dose radiation are assumed to be small compared to the risks that may arise from other lifestyle factors; therefore, the benefits of radiation use should be considered at the individual level through a balanced interpretation. Further low-dose radiation studies are essential to accurately determining the benefits and risks of radiation.

Dose Reduction Factors for High-Exposure Tasks at Korean Pressurized Water Reactors

  • Changju Song;Tae Young Kong;Seongjun Kim;Jinho Son;Jiung Kim;Jaeok Park;Hee Geun Kim;Yongkwon Kim;Hyungkwon Jung
    • 방사선산업학회지
    • /
    • 제18권1호
    • /
    • pp.23-33
    • /
    • 2024
  • This study was conducted to analyze the characteristics of three high-exposure tasks performed by radiation workers in Korean pressurized water reactors (PWRs) and to identify factors that reduce their exposure during work. Three high-exposure tasks were selected based on a previous study. In this previous study, nozzle dam installation and removal, eddy current testing, and manway opening and closing were determined as high-exposure tasks through normalization (radiation dose per unit time). Based on the analysis of the characteristics of the high-exposure tasks in this study, the high-exposure tasks were steam generator-related tasks performed inside and outside the water chamber. This study analyzed the reduction factors for high-exposure tasks and suggested improvements in terms of time, distance, and shielding. The use of the characteristics of high-exposure tasks and their dose reduction factors enables Korean PWRs to optimize radiation protection for workers who receive relatively high doses.