• Journal of the Korean Wood Science and Technology
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• v.46 no.5
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• pp.497-510
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• 2018

In this study, the decay resistance of larch wood, which was heat treated by superheated steam, was evaluated by the field decay test. During the field decay test of 12 months, non-treated wood has been severely damaged by termite, however, no visible damage has occurred in the preservative-treated wood and superheated steam heat-treated wood. Results of field decay test showed approximately 5% mass loss of the non-treated wood and the preservative-treated wood, and approximately 1% mass loss of the superheated steam heat-treated wood. After the field decay test for 12 months, the residual amount of preservatives remaining in the preservative-treated wood was lower than that before the field decay test. It was considered that the preservative was partially eluted during the field decay test, and the mass loss of the preservative-treated wood was thought to be similar to that of the non-treated wood. Through this study and additional long-term monitoring test, superheated steam heat treatment can be considered to be an environmental-friendly method to enhance the decay resistance of wood against rot fungi and/or insect without chemical treatment such as preservative injection.

• Journal of The Korean Society of Grassland and Forage Science
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• v.24 no.1
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• pp.25-28
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• 2004

To determine lethal temperature of orchardgrass (Dactylis glomerata L. cv. Janbeol 102) developed in Korea at heat-stressed conditions, seedlings grown in a amall pots for 4 weeks were treated at $45^{\circ}C$, $50^{\circ}C$ or $55^{\circ}C$ for 1 h. Heat treatments at $60^{\circ}C$ and $65^{\circ}C$ for 1 h, several plants were withered and showed damage symptom on their leaves. When the plants were exposed to $70^{\circ}C$ for 1 h, most of leaves were severely withered, but it was not lethal conditions for the whole plants. By contrast, most of plants were died within one day after heat treatment at $80^{\circ}C$ for 1h. Furthermore, plants exposed to $80^{\circ}C$ for 55 min were also died within 7 days. It was found that new shoots were regenerated from the plants that had been treated at $80^{\circ}C$ within 50 min. These results indicate that heat treatment at $80^{\circ}C$ for 55 min is an optimum condition to distinguish the lethality of orchardgrass plants. Simple viability assay system established in this study will be useful for selection and characterization of heat-tolerant transgenic orchardgrass plants.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.48 no.2
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• pp.157-167
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• 2022

In this study, we investigated the effects of heptapeptide on cellular activation and inhibition of cellular damage induced by photoaging condition in NIH3T3 fibroblasts. Cell proliferation and extracellular matrix (ECM) expression were induced by heptapeptide. The reduced cell viability under photoaging condition through ultraviolet A (UVA) irradiation was increased by heptapeptide. And UVA-induced apoptosis, matrix metalloproteinases-1 (MMP-1) expression, and reactive oxygen species (ROS) level were decreased by heptapeptide. In addition, the inhibition of transforming growth factor-β (TGF-β)/smad signaling under UVA irradiation which resulting in reduction of ECM expression was also recovered by heptapeptide. We also tested the effect of heptapeptide under another photoaging condition through heat shock, and pre-treatment of heptapeptide prevented the phosphorylation of mitogen-activated protein kinase (MAPK) and MMP-1 expression induced by heat shock. From these results, it has been shown that the heptapeptide has protective effects on fibroblasts through the up-regulation of cellular activity and through the decreasing of intracellular ROS level induced by UVA irradiation or heat shock. It is expected that the dermal protection effect of heptapeptide can be applied as a new cosmetic material in the future.

• Fire Science and Engineering
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• v.25 no.6
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• pp.32-38
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• 2011

As the using rate of an explosive gas has been increased in the industrial site, the regional residents adjacent to the site as well as the site workers have frequently fallen into a dangerous situation. Damage caused by accident in the process using hydrogen gas is not confined only to the relevant process, but also is linked to a large scale of fire or explosion and it bring about heavy casualties. Therefore, personnel in charge should investigate the kinds and causes of the accident, forecast the scale of damage and also, shall establish and manage safety countermeasures. We, in Anti-Calamity Research Center, forecasted the scope of danger if break out a fire or/and explosion in hydrogen gas facilities of MLCC firing process. We selected piping leak accident, which is the most frequent accident case based on an actual analysis of accident data occurred. We select and apply piping leak accident which is the most frequent case based on an actual accident data as a model of damage forecasting scenario caused by accident. A jet fire breaks out if hydrogen gas leaks through pipe size of 10 mm ${\Phi}$ under pressure of 120 bar, and in case of $4kw/m^2$ of radiation level, the radiation heat can produce an effect on up to distance of maximum 12.45 meter. Herein, we are going to recommend safety security and countermeasures for improvement through forecasting of accident damages.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.7
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• pp.4626-4633
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• 2014

The research is being conducted on a SFT (Submerged Floating Tunnel), because of increased exchange among nations and abnormal weather-disasters and new transportation infrastructure has attracted interest. However, studies in this are almost in the early stages around the world and various researches will be needed to promote the safety form the disaster. In this paper, heat transfer analysis was applied among the structural performance evaluation of a SFT if afire occurs in the tunnel. The analysis model of the SFT was performed as steel composite RC hollow. The impact of heat by fire under a range of fire scenarios was analyzed and prevention techniques were examined.

• Journal of Hydrogen and New Energy
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• v.31 no.1
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• pp.82-88
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• 2020

Recently, a fuel reforming plant for supplying high purity hydrogen has been studied to increase the operation time of underwater weapon systems. Since steam reforming is an endothermic reaction, it is necessary to continuously supply heat to the reactor. A fuel reforming plant needs a methanol-O₂ catalytic burner to obtain heat and supply heat to the reformer. In this study, two types of designs of a catalytic burner are presented and the results are analyzed through the experiments. The design of the catalytic burner is divided into that the O₂ supply direction is perpendicular to the methanol flow direction (Design 1) and the same as the methanol flow direction (Design 2). In case of Design 1, backfire and flame combustion occurred in the mixing space in front of the catalyst, and in the absence of the mixing space, combustion reaction occurred only in a part of the catalyst. For above reasons, Design 1 could not increase the exhaust gas temperature to 750℃. In Design 2, no flashback and flame combustion were observed, the exhaust gas could be maintained up to 750℃. However, the O₂ distributor was exposed to high temperatures, resulting in thermal damage.

• Biomolecules & Therapeutics
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• v.26 no.6
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• pp.576-583
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• 2018

Human rhinoviruses (HRV) are one of the major causes of common cold in humans and are also associated with acute asthma and bronchial illness. Heat-shock protein 90 (Hsp90), a molecular chaperone, is an important host factor for the replication of single-strand RNA viruses. In the current study, we examined the effect of the Hsp90 inhibitor pochonin D, in vitro and in vivo, using a murine model of human rhinovirus type 1B (HRV1B) infection. Our data suggested that Hsp90 inhibition significantly reduced the inflammatory cytokine production and lung damage caused by HRV1B infection. The viral titer was significantly lowered in HRV1B-infected lungs and in Hela cells upon treatment with pochonin D. Infiltration of innate immune cells including granulocytes and monocytes was also reduced in the bronchoalveolar lavage (BAL) by pochonin D treatment after HRV1B infection. Histological analysis of the lung and respiratory tract showed that pochonin D protected the mice from HRV1B infection. Collectively, our results suggest that the Hsp90 inhibitor, pochonin D, could be an attractive antiviral therapeutic for treating HRV infection.

• Herbal Formula Science
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• v.12 no.2
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• pp.1-17
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• 2004

This study was investigated to make sure the range of the Morus Cortex's treatment, the nature of disease, the chief virtue of medicine, the pathology and the usage quantity of it in Donguibogam The results were as follows; 1. The frequency of being used the Morus Cortex in the consumption or cough-relative chapter is as high as a ratio of 40.6%. 2. The Morus Cortex is used in a realm of the consumption or cough-relative disease, an otorhinolalyngology, an edema, a skin-relative disease, a bleeding trouble, a thirsty and diabetes melitus, etc. 3. The Morus Cortex is used in a realm of the pathology of the pulmonary heat, the pulmonary noxious vigor, the damage from external winds and colds, fatigue, etc. 4. The Morus Cortex is used in a range of $1g{\sim}12g$ in herbal-prescription. The main using dosage is 4g(about 42%). 5. The Morus Cortex is used with various crude herbs in accordance with the pathogeny. The Morus Cortex has been used to reduce heat from the lungs and soothe asthma, to promote urination and reduce edema from shinnongboncho era. According to the results, I suggest that we use the Morus Cortex in a various pathogenic fields. The Morus Cortex is able to remove not only pathogenic heat from the consumption or cough-relative disease, but also pathogenic otorhinolalyngology, an edema, a skin-relative disease, a bleeding trouble, a thirsty and diabetes melitus, etc.

• The Korean Journal of Physiology and Pharmacology
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• v.12 no.4
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• pp.171-176
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• 2008

Heat shock proteins (HSPs) serve as molecular chaperones and play a role in cell protection from damage in response to stress stimuli. The aim of this article is to investigate whether HSP22 affects IL-8 expression in vascular smooth muscle cells (VSMCs), and which cellular factors are involved in the HSP-mediated IL-8 induction in that cell type in terms of mitogen activated protein kinase (MAPK) and transcription element. Exposure of aortic smooth muscle cells (AoSMCs) to HSP22 not only enhanced IL-8 release but also induced IL-8 transcript via promoter activation. HSP22 activated ERK and p38 MAPK in AoSMCs. HSP22-induced IL-8 release was inhibited by U0126, but not by SB202190. A mutation in the IL-8 promoter region at the binding site of NF-${\kappa}$ B, but not AP-1 or C/EBP, impaired promoter activation in response to HSP22. Delivery of I ${\kappa}$ B, but not dominant negative c-Jun, lowered HSP22-induced IL-8 release from AoSMCs. These results suggest that HS P22 induces IL-8 in VSMCs via ERK1/2, and that transcription factor NF-kB may be required for the HSP22-induced IL-8 up-regulation.

• KIEAE Journal
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• v.16 no.6
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• pp.69-75
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• 2016

Climate change has resulted in the urban heat island (UHI) effect throughout the globe, contributing to heat-related illness and fatalities. In order to reduce such damage, it is necessary to improve the climate observation network for precise observation of the urban thermal environment and quick UHI forecasting system. Purpose: This study analyzed the effective range of the climate observation network and the distribution of the existing Automatic Weather Stations (AWS) in Seoul to propose optimal locations for additional installment of AWS. Method: First, we performed quality analysis to pinpoint missing values and outliers within the high-density temperature data measured. With the result from the analysis, a spatial autocorrelation structure in the temperature data was tested to draw the effective range and correlation distance for each major time period. Result: As a result, it turned out that the optimal effective range for the climate observation network in Seoul in July was a radius of 2.8 kilometers. Based on this result, population density, and temperature data, we selected the locations for additional installment of AWS. This study is expected to be used to generate urban temperature maps, select and move measurement locations since it is able to suggest valid, specific spatial ranges when the data measured in point is converted into surface data.