• Title/Summary/Keyword: health science

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Comparison of Four Commercial ELISA Kits and In-House Immunoblotting for Diagnosis of Helicobacter pylori Infection

  • Jeong, Hoar Lim;Jung, Yang-Sook;Jun, Jin-Su;Yeom, Jung Sook;Park, Ji Sook;Seo, Ji-Hyun;Lim, Jae-Young;Park, Chan-Hoo;Woo, Hyang-Ok;Youn, Hee-Shang;Ko, Gyung-Hyuck;Baik, Seung-Chul;Lee, Woo-Kon;Cho, Myung-Je;Rhee, Kwang-Ho
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.15 no.2
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    • pp.85-90
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    • 2012
  • Purpose: Commercial enzyme-linked immunosorbent assay (ELISA) kits have been considered less reliable for children than for adults. The aim of this study was to compare four ELISA kits and in-house immunoblotting based on the analysis of anti-H. pylori-IgG antibody reactivity. Methods: A total of 399 serum samples were collected at the GNU Hospital during 1998-1999. All sera were tested using ELISA and immunoblotting. Statistically significant differences were determined by the $x^2$ test. Results: The overall seropositivity rates using GAP IgG, Genedia IgG, HM-CAP, Pyloriset EIA-G, and immunoblotting were 13.0%, 25.1%, 18.3%, 15.8%, and 62.9%, respectively. Immunoblotting showed a higher seropositivity rate than did all four ELISA kits in all age groups. Genedia IgG had the highest seropositivity among the ELISA kits. The seropositivity rate for children aged 13 to 18 months was lowest, and that of children aged 15 years was highest (90.0%). The seropositivity rate for children aged 7 months to 5 years was significantly lower than that for children aged 6 to 15 years among the four ELISA kits (p<0.0001) and immunoblotting (p=0.02). Conclusion: Immunoblotting is the most sensitive test for detection of anti-Helicobacter pylori IgG antibodies among the serological tests in this study. These results emphasize the need for standardization when commercial ELISA tests are used in different nations or in young age groups. Immunoblotting could be a suitable noninvasive assay for serodiagnosis and seroepidemiologic study of H. pylori infection in Korean children.

Analysis of Community-based Health Promotion Program Targeting School-aged Children and Program Using Forest: Based on National Community Health Plan (학령기아동 대상 지역사회 건강증진 프로그램 및 숲을 활용한 프로그램 분석: 전국 지역보건의료계획을 기반으로)

  • Lee, Insook;Bang, Kyung-Sook;Kim, Sung-Jae;Choi, Heeseung;Hwang, Inju;Kim, Jieun
    • Korean Parent-Child Health Journal
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    • v.17 no.1
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    • pp.8-17
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    • 2014
  • Purpose: The purpose of this study is to analyze community-based health promotion program for school-aged children and program using forest. Methods: Seventeen health promotion programs focused on school-aged children from Community Health Plan were selected to analyze after assembling 227 of the 5th National Community Health Plans. The analysis duration was from 2012 July to November. Results: Among 17 programs, the health promotion program targeting school-aged children were included in 16 programs except one program focusing on community- orientated rehabilitation program. Eight health promotion programs using forest in 7 different areas were found. The majority of the community-based health promotion programs were focused mainly on smoking cessation, obesity, physical activity, nutrition, mental health programs. Furthermore, there was a limitation of programs utilizing forest as a health promotion resource and most of the programs using forest were located in Jeollanamdo and focusing mainly on atopy prevention and treatment. Conclusion: The importance of this study is that it analyzed nation-wide community health plan systematically, and analyze community-based health promotion program targeting school-aged and the program using forest. The results of the analysis can be used as baseline data for developing physical and mental health promotion programs using forest targeting school-aged children.

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Development and Implementation of Health Systems Science Education in the Clinical Learning Environment (의료시스템과학 교육의 임상실습 적용 사례 개발과 적용)

  • Sang-Hoon Na
    • Korean Medical Education Review
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    • v.25 no.3
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    • pp.229-242
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    • 2023
  • Health systems science is a new medical educational field added to the traditional medical education curricula of basic and clinical sciences. Health systems science emphasizes a more comprehensive approach utilizing systems thinking to care for patients, including interactions between multiple healthcare systems. In this review, I explore how health systems science education can be applied when medical instructors teach students in clinical clerkships through representative case studies. This study first looks at examples of health systems science education in clinical clerkship in the United States and suggests how to develop the curriculum of health systems science for clinical learning environments in Korea by combining Kotter's 8-step change management model and Kern's 6-step curriculum development model. Finally, based on practical examples from actual clinical practice education situations, suggestions are made regarding how to develop the entire educational program of a medical school from the stage of applying health systems science at the individual level to clinical practice education.

An Analysis of Health Promotion Programs Utilizing Forests based on Korea's Regional Healthcare Program Plans (지역보건의료계획에 근거한 보건소 숲 건강증진 프로그램 현황)

  • Lee, Insook;Kim, Sungjae;Bang, Kyung-Sook;Choi, Heeseung;Ko, Chinkang;Kim, Jieun;Kim, Sunyoung
    • Perspectives in Nursing Science
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    • v.11 no.1
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    • pp.10-17
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    • 2014
  • Purpose: The aim of this study was to analyze health promotion programs utilizing forests by reviewing regional healthcare program plans in Korea. Methods: We analyzed 227 regional healthcare program plans from 2011 to 2014; seven health promotion programs of the 16 major healthcare programs were prescribed by public health law. Results: Our analysis revealed that only 35 health promotion programs from 29 sites were utilizing forests. Furthermore, of 21 known categories of health promotion programs, only nine incorporated the use of forests. Atopy-asthma healthcare programs were the most common forest health promotion programs, which also included specialized disease management programs (e.g., for atopy prevention and healing, patients with metabolic syndrome or cancer) and specialized mental health management programs (e.g., for addiction or dementia prevention). Others included programs on the development of forest roads or industrial development using forest products. Conclusion: Health programs using forests in Korea are still very limited and primarily comprise atopy-asthma prevention/management, health behavioral change, and mental health programs. This study provided useful information for developing health policies and forest health promotion programs further in Korea.

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Determinants of health-promoting behavior among eHealth consumers in South Korea: a longitudinal path analysis

  • Hanna Choi;Meiling Jin
    • Journal of Korean Biological Nursing Science
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    • v.26 no.3
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    • pp.206-217
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    • 2024
  • Purpose: The study aimed to determine the key factors influencing health-promoting behavior and the behavioral intentions of eHealth consumers based on the health promotion model and technology acceptance model. Methods: This research involved a longitudinal path analysis. The study was conducted with 360 eHealth consumers aged over 18 years, employed in the top five categories of the Korean standard classification of occupations, and living in the five largest cities in South Korea. The data were analyzed using SPSS 22.0 and AMOS 25.0. Results: Health-promoting behaviors were directly supported by prior health-related behavior and behavioral intention, and indirectly supported by perceived ease of use, perceived usefulness, perceived benefit, self-efficacy, and behavioral intention. These variables accounted for 36.3% of the variance in health-promoting behavior. Conclusion: The findings serve as a framework that can help health professionals and health information providers understand how to encourage consumers using eHealth to engage in health-promoting behaviors.

Characterization of airborne bioaerosol concentration at the apartment in chungnam area

  • Son, Bu-Soon;Park, Jong-An;Song, Mi-Ra;Yang, Won-Ho;Jung, Hong-Ryang
    • Proceedings of the Korean Environmental Health Society Conference
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    • 2005.12a
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    • pp.83-84
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    • 2005
  • This research was performed to measure the concentration distribution of Bioaero sol in apartment houses in the region of Chungnam (Chunan, Asan) for 1 month, December, 2004. The results are as follows.

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A Study on the Health Status and the Needs of Health-related Services of Female Elderly in an Urban-rural Combined City (여성노인의 건강상태와 건강관련서비스 요구)

  • Kang Young Sil;Kim Eun Sim;Gu Mee Ock;Eun Young
    • Journal of Korean Public Health Nursing
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    • v.17 no.1
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    • pp.47-57
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    • 2003
  • The purpose of this study was to investigate health status and health promoting behaviors of female elderly, and their needs for health-related services in an urban-rural combined city. The data were collected from the subjects registered in senior welfare center and senior citizens' clubs. A total of 119 women were participated in the survey. The results of the study are as follows; 1. The subjects perceived their health status relatively unhealthy. Their health promotion behavior score was 10.82 (range 0-17), and more than $60\%$ of them performed well in smoking and drinking control, regular meal. taking breakfast, and maintaining good relationship with others. 2. The most needed service was health screening followed by health risk assessment, disease diagnosis and treatment. 3. The most demanded education was on dementia prevention, followed by exercise, balanced diet, and maintenance of memorial and mental capability. 4. As the health interest and the health responsibility increased, the need for health service increased as well. Likewise, the health education needs increased as the health interest, health responsibility, and health promotion behavior increased. The results show that the health promotion programs for female elderly need to be focused, primarily, on health screening, health risk assessment, medical services for disease diagnosis and treatment, and health consulting and education. And health consulting and education programs should be designed to promote health interest and health responsibility of female elderly, change positively their attitude to aging, and include education on dementia prevention, exercise and nutrition management. Recommendations are discussed.

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Current Evidence on the Association between rs3757318 of C6orf97 and Breast Cancer Risk: a Meta-Analysis

  • Hong, Yuan;Chen, Xue-Qin;Li, Jiao-Yuan;Liu, Cheng;Shen, Na;Zhu, Bei-Bei;Gong, Jing;Chen, Wei
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.19
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    • pp.8051-8055
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    • 2014
  • Background: A common genetic variant rs3757318, located in intron of C6orf97, was firstly identified to be associated with breast cancer (BC) risk by a genome-wide association (GWA) study. However, subsequent validation studies with different ethnicities have yielded conflicting results. Materials and Methods: We performed a meta-analysis to synthesize all available data for evaluating the precise effect of this variant on BC susceptibility. Results: A total of 8 articles containing 11 studies with 62,891 cases and 65,635 controls were included in this meta-analysis. When compared to the G allele, the rs3757318-A allele was significantly associated with BC risk with the pooled OR of 1.21 (95% CI=1.15 - 1.29, P<0.001) but with obvious between-study heterogeneity (P=0.040). Stratified analysis suggested that diversity of ethnicity along with control source may explain part of the heterogeneity. Similarly, significant associations were also identified in heterozygote, homozygote, dominant and recessive genetic models. Sensitivity and publication bias analyses indicated robust stability of our results. Conclusions: Our present meta-analysis demonstrated that the variant rs3757318 is associated with increased BC risk. Nevertheless, further studies are needed to clarify the underlying biological mechanisms.