• Child Health Nursing Research
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• v.26 no.4
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• pp.463-469
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• 2020

Reduction of the under-5 mortality rate is a target of the Sustainable Development Goals. Therefore, this study aimed to estimate under-5 child mortality rates in 52 low-migration countries using population data. The study utilized population data from the US Census Bureau from 1990 to 2015. The method involved first estimating mortality rates for countries with negligible net migration and then applying these rates to countries with matching mortality profiles, where it is reasonable to assume that migration is negligible for children under the age of 5 years. The highest child mortality was concentrated in the African region, followed by Asia and the Western region. However, steady progress in child mortality trends was concentrated in low-income countries. This simple method demonstrated that child mortality has significantly improved in high-income countries, followed by middle- and low-income countries. To reduce the under-5 mortality rates even further in these 52 countries, there is a need to accelerate equitable plans and policies related to child health to promote children's longevity and survival.

• Journal of Environmental Health Sciences
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• v.41 no.3
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• pp.216-221
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• 2015

Since Patient Zero of MERS was diagnosed in May 20, 2015, cases of MERS continued to grow. The current situation, which people have been confirmed to be infected, suggested that contaminated indoor air could be the potential cause of hospital-acquired infections. It is important to address the indoor air quality in hospitals because pathogens can spread through air. While the heating, ventilating and air conditioning(HVAC) system is useful managing indoor air quality in hospitals, it can transmit the pathogens if operated improperly. Therefore, it is necessary to remove contaminants in hospitals and operate the HVAC system according to the guidelines, in order to maintain clean indoor air.

• Journal of the Ergonomics Society of Korea
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• v.32 no.6
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• pp.495-501
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• 2013

Objective: The purpose of this study was to survey of the subjective health status of the elderly farmer. Background: With increase of aged population, the health of the elderly farmer has become main concerns of the elderly in the rural community. For the effects of the factors related to quality of life, subjective health condition showed the largest influence. Method: The survey was conducted by 326 elderly farmers aged 50 and older in rural areas through structured questionnaires. Survey questionnaire consisted items of general characteristics, health-related life habits, levels of stress(SF-PWI), symptom of musculoskeletal diseases and general level of health(SF-36). For the data analysis, SPSS 19.0K was used, and analysis was conducted by using frequency, percentage, mean, and standard deviation. For the symptom prevalence of musculoskeletal disorders and comparison of average level of health, chi-square test and t-test were used. Results: The results of the study are as follows. It was shown that the symptom prevalence of musculoskeletal disorders had a significant difference in gender (p<0.01). Frequency analysis on presence of musculoskeletal symptoms in each part of body showed that leg/knee region was 28.1%, back region was 26.6%, shoulder region was 18.0%, arm/elbow region was 11.9%, hand/wrist region was 8.2% and neck region was 7.2%. According to comparison of average level of health, a social functioning were the highest as score 87.3, followed by mental health(65.6) and role limitation-emotional(65.5). Conclusion: Health promotion program for the elderly and female in the rural are needed. Application: The survey of the subjective health status of the elderly should be used for planning factors to make a health improvement plan in elderly farmer.

• Korean Journal of Adult Nursing
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• v.17 no.4
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• pp.668-678
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• 2005

Purpose: The purpose of this study was to provide the basic data of a comprehensive counter-plan to promote health for people by comparing various factors related to cancer outbreak factors including general characteristics, health-related lifestyles, health promoting behaviors, perceived healthy status, life event stress and health care seeking behaviors with cancer patients and health people. Method: The study was designed to be a retrospective-comparison-survey-study and its data was collected through 5 types of questionnaires from September 2003 to December 2003. Results: Cancer patients had lower education and household income, and many of them had no occupation. Cancer patients had a higher rate of smoking and drinking periods. Exercise level was higher in healthy people. However, Cancer patients were better in sleep and rest. In comparison with health promoting behaviors, it was higher in healthy people than in cancer patients but the two groups had no significant differences statistically. The perceived health status was higher in healthy people than in cancer patients. The health care seeking behaviors were higher in healthy people than in cancer patients. Cancer patients and healthy people's life event stress had no significant differences statistically. Conclusion: As a result of comparative analysis of cancer patients and healthy people's health risk factors, smoking, drinking period, regular exercise and health care seeking behaviors were suggested as direct or indirect risk factors for cancer patients. These finding can be applied to health promoting behavior programs to keep and promote optimal health status as well as to prevent cancer disease.

• Journal of Korean society of Dental Hygiene
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• v.17 no.2
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• pp.225-234
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• 2017

Objectives: The purpose of this study was to investigate the effect subjective symptoms of malocclusion has on the patient's quality of life related to oral health. Methods: A self-administered survey was conducted on adults aged 20 years, with a total of 308 copies of the response sheets analyzed. Results: The degree of subjective symptoms of malocclusion was highest in the group of those in their 20s when looked at across different age groups, and those who had a final education of middle school. In addition, the quality of life related to oral health was the highest in middle school graduates and among those in Gyeonggi province. The degree of malocclusion symptom according to oral health behavior was highest in 1-2 weeks of drinking when smoking in a smoking state, and quality of life related to oral health was higher in smokers than in non-smokers. The greater the subjective symptoms of malocclusion, the lower the quality of life related to oral health. Conclusions: It was found that the subjective symptoms of malocclusion decreased quality of life related to oral health. As such, quality of life related to oral health can be improved through aesthetic and functional improvement efforts to decrease the subjective symptoms of malocclusion.

• 한국약용작물학회:학술대회논문집
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• 2010.10a
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• pp.343-344
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• 2010

• Development and Reproduction
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• v.23 no.2
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• pp.129-138
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• 2019

In many cases, obesity is associated with metabolic disorders. Recently, natural compounds that may be beneficial for improving obesity have received increasing attention. Bitter melon has received attention as a diabetes treatment. $NAD^+$-dependent deacetylase (Sirtuin 1, SIRT1) has emerged as a novel therapeutic target for metabolic diseases. In this study, ethanol extract of bitter melon (BME) suppressed adipocyte differentiation and significantly increased the expression of SIRT1 in fully differentiated 3T3-L1 cells. Moreover, it enhanced the activation of AMP-activated protein kinase (AMPK). In high-fat diet (HFD)-fed induced-obesity mice, BME suppressed HFD-induced increases in body weight and white adipose tissue (WAT) weight. BME also increased the expression of SIRT1 and suppressed peroxisome proliferator-activated receptor and sterol regulatory element binding protein 1 expressions of WAT from HFD-fed mice. These findings suggest that BME prevents obesity by activating the SIRT1 and AMPK pathway and that it may be a useful dietary supplement for preventing obesity.

• Korean Journal of Veterinary Service
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• v.41 no.4
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• pp.221-228
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• 2018

Rumen cannulation is used for nutritional and microbiological research, clinical diagnosis, and rumen component transfaunation. However, the cannulation procedure can affect parameters such as complete blood count findings, serum chemistry, and rumen fluid pH. The objective of this study was to evaluate the health risks related to the rumen cannulation procedure over a 1-month period. We did not identify significant differences in red blood cell numbers or morphologies between pre- and postoperative timepoints. Moreover, no inflammation or infection was detected. Despite the absence of apparent clinical signs after surgery, serum chemistry results revealed changes in blood urea nitrogen levels and the activities of liver enzymes, including aspartate transaminase, lactate dehydrogenase, and creatinine kinase, from postoperative days 1 to 14. Rumen fluid pH, as measured from samples collected via an orogastric tube, was slightly increased after a preoperative fasting period and on postoperative day 1 but decreased thereafter from postoperative day 4, indicating a minor influence of cannulation surgery on ruminal fluid pH. This is the first study to evaluate hematological parameters and rumen pH before and after rumen cannulation surgery in Hanwoo cattle. Further research is required to better elucidate the potential effects of rumen cannulation surgery on animal health.

• The Journal of Korean Physical Therapy
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• v.35 no.3
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• pp.57-63
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• 2023

Purpose: The aim of this study was to conduct a systematic review of randomized controlled studies from 2012 to present that explore the diagnostic accuracy of clinical tests used for diagnosing anterior cruciate ligament (ACL) injury. Methods: Study design: Systematic review. Literature search of the PubMed and Scholar databases was conducted using keywords related to diagnostic accuracy of clinical tests for ACL injury. The PRISMA Guidelines were followed to conduct this study. The Cochrane Risk of Bias Tool was utilized to assess the quality of each included study. Results: As a result, 8 studies were included, and 6 clinical tests used in ACL tears were evaluated for diagnostic accuracy. The pivot shift test was reported as having the highest +LR (29.5) value with a sensitivity of 59% and a specificity of 98%. However, the test with the lowest -LR value was the lever test, and the values were as follows: -LR (0.08), +LR (4.7), specificity (80%), sensitivity (94%). Conclusion: In this study, it was concluded that a single clinical test is not sufficient to determine the presence of ACL injury. Test combinations have a higher diagnostic accuracy than a single test. In this study, the accuracy of the clinical tests was examined without considering the amount of ACL rupture and acute-chronic condition. Further research is required to examine the impact of these two factors on diagnostic accuracy of clinical test.

• Molecules and Cells
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• v.43 no.8
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• pp.749-762
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• 2020

The migration, dedifferentiation, and proliferation of vascular smooth muscle cells (VSMCs) are responsible for intimal hyperplasia, but the mechanism of this process has not been elucidated. WD repeat domain 1 (WDR1) promotes actin-depolymerizing factor (ADF)/cofilin-mediated depolymerization of actin filaments (F-actin). The role of WDR1 in neointima formation and progression is still unknown. A model of intimal thickening was constructed by ligating the left common carotid artery in Wdr1 deletion mice, and H&E staining showed that Wdr1 deficiency significantly inhibits neointima formation. We also report that STAT3 promotes the proliferation and migration of VSMCs by directly promoting WDR1 transcription. Mechanistically, we clarified that WDR1 promotes the proliferation and migration of VSMCs and neointima formation is regulated by the activation of the JAK2/STAT3/WDR1 axis.