• Title/Summary/Keyword: harmful drug

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Clean Analysis Not to Use Harmful Solvent for TLC Identification Test of the Herbal Medicine (생약의 확인시험법에 대한 유해용매 대체시험법 설정)

  • Kim, Ji-Yeon;Park, Ju-Young;Shim, Young-Hoon;Cho, Chang-Hee;Lee, Jong-Hwa;Lee, Dong-Jin;Kim, Bo-Joon;Kim, Dong-Sup;Seong, Rack-Seon;Kim, Jong-Hwan;Lim, Sook;Shin, Jin-Seon;Jang, Seung-Yeup
    • Korean Journal of Pharmacognosy
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    • v.41 no.2
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    • pp.136-140
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    • 2010
  • This study was carried out to utilize non-toxic solvents instead of harmful solvents for the TLC(Thin Layer Chromatography) identification test of herbal medicines. It is recommended not to use harmful solvent such as chloroform at a viewpoint of clean analysis. In this study, we revised the identification test of 10 items in the Korea Pharmacopoeia(KP) and the Korean Herbal Pharmacopoeia(KHP) such as Cornus officinalis S. containing the harmful solvents on the developing solvent and established identification test that is utilized non-toxic solvents by HPTLC(High Performance Thin Layer Chromatography).

Harmful Environments (유해환경)

  • Doh, Hyun-Sim;Lee, Sa-Rah;Song, Seung-Min
    • Korean Journal of Child Studies
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    • v.30 no.6
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    • pp.125-137
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    • 2009
  • This study reviews facts and trends of harmful environments in the last decade that negatively affected children's development. Younger children have been exposed to harmful media, drugs, facilities, and objects. A matter of chemical substances contaminating in-door air has become quite controversial, recently. In order to provide a better understanding of harmful environments against children, there are great needs for a survey covering all ages based on the clear definition of the term harmful environments, research identifying its causal effects on child development in the context of both parent-child and peer relationships, and a longitudinal study processing its effects in a life-span perspective. It is suggested that by providing parent education and a plenty of cultural facilities as social efforts to create sound family culture, psycho-social and physical environments of children are improved. Furthermore, legal regulations and supervision on harmful environments are needed to be strengthened.

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Illegal and Harmful Information Detection Technique Using Combination of Search Words (단어 조합 검색을 이용한 불법·유해정보 탐지 기법)

  • Han, Byeong Woo;Yoon, Ji Won
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.26 no.2
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    • pp.397-404
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    • 2016
  • Illegal and harmful contents on the Internet has been an issue and been increased in Korea. They are often posted on the billboard and website of small enterprise and government office. Those illegal and harmful contents can relate to crime and suspicious activity, so, we need a detection system. However, to date the detection itself has been conducted manually by a person. In this paper, we develop an automated URL detection scheme for detecting a drug trafficking by using Google. This system works by analyzing the frequently used keywords in a drug trafficking and generate a keyword dictionary to store words for future search. The suspected drug trafficking URL are automatically collected based on the keyword dictionary by using Google search engine. The suspicious URL can be detected by classifying and numbering each domain from the collection of the suspected URL. This proposed automated URL detection can be an effective solution for detecting a drug trafficking, also reducing time and effort consumed by human-based URL detection.

Development and Evaluation of Consumer Educational Contents on Hazard Chemicals in Food for Female College Students in Seoul (식품 중 유해물질에 대한 소비자 교육 콘텐츠 개발 및 교육효과 조사 -서울에 거주하는 여대생을 중심으로-)

  • Cho, Sun-Duk;Kang, Eun-Jin;Kim, Meehye;Park, Sung-Kug;Paek, Ock-Jin;Kim, Gun-Hee
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.42 no.10
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    • pp.1701-1706
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    • 2013
  • Domestic and overseas information with regard to harmful substances are analyzed. From the results, environmental-derived hazard chemicals, which show relatively low recognition, and hazard chemicals that occur unavoidably in food manufacturing process are selected as target harmful substances. Thus, educational leaflet contents were developed based on these substances. To find the effects of education with the above contents, this study surveyed 120 female college students living in Seoul. The purpose of the survey is to analyze the change in recognition, attitude and behavior on hazard chemicals in foods. The survey found that the recognition on harmful substance in foods increased; from 31.5~78.0% before education to 98.8% after education. It also indicates that vague anxiety in which the harmful substances may damage their health decreased by approx. 25.0%; from 77.8% before education to 52.8% after education. For the question of what they would do when government promotes to reduce harmful substances in foods, 12.3% of respondents said that they would actively follow the suggestions and 73.5% of them said that they would do their best before an education. However, 56.1% of them said that they would actively follow the suggestions after the education. It indicates that the ability to recognize harmful substances changed after the education. With regard to consumer behavior, when they knew about the harmful substances in foods, 49.6% of them said that they would select foods after investigating relevant information before the education, while 77.4% of them said that after the education; which is an increase of 27.8%. Further, 45.4% of them said that they would not purchase relevant foods before the education, while 20.9% of them said that after the education; which is a decrease of 24.5%. Therefore, it is considered that vague anxiety of consumers can be eliminated by providing persuasive information on harmful substances. To expand on the communication channel with consumers for food safety, contents development and educational promotion should be enhanced for providing food safety related information.

Establishment of analytical methods for HPHC list of mainstream cigarette smoke (담배 주류연 중 7개 그룹의 유해성분(HPHC) 분석법 확립 및 유효성 평가)

  • Park, Hyoung-Joon;Lee, Jin-Hee;Cho, So-Hyun;Heo, Seok;Yoon, Chang-yong;Baek, Sun-Young
    • Analytical Science and Technology
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    • v.28 no.6
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    • pp.385-397
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    • 2015
  • Harmful and potentially harmful constituents (HPHCs) are chemical compounds in tobacco smoke that cause harm to smokers and non-smokers. This study established and validated methods for the analysis of HPHCs from mainstream cigarette smoke. The analyzed HPHCs were categorized into seven groups: aromatic amines, volatile organic compounds (VOCs), heavy metals, tobacco specific nitrosamines (TSNAs), benzo[a]pyrene (B[a]P), ammonia, and carbonyl compounds. The methods were validated by specificity, linearity, limit of detection (LOD), accuracy, precision, and recovery. These validated methods were then applied to the reference cigarettes (1R5F, 3R4F). The correlation coefficients (r2) for the calibration curves of the seven groups were over 0.995. The LODs showed values of 0.01-0.04 ng/cig cig for aromatic amines, 0.01-0.16 μg/cig for VOCs, 0.01-1.27 ng/cig for heavy metals, 0.06-0.28 ng/cig for TSNAs, 0.04 ng/cig for benzo[a]pyrene, 0.08 μg/cig for ammonia, and 0.78-1.77 μg/cig for carbonyl compounds. The precisions obtained from the intra and inter-day batches were less than 15%. The accuracy and the recovery range were less than 15% and 79.2-117.5%, respectively. The proposed methods can therefore be applied for determining HPHCs in tobacco mainstream smoke.

Current Status and Perception of Abused Drugs by Gender Among Young People (청년층의 성별에 따른 남용약물에 대한 사용실태와 인식)

  • Hyun-Ju, Jeong;Jeong-Sook, Park
    • Journal of Industrial Convergence
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    • v.21 no.2
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    • pp.79-84
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    • 2023
  • This study was analyzed based on 1051 analyzes of questionnaires in order to examine the status and perception of abused drugs according to the gender of the young people entering the adult group from the adolescents. The gender of the young people who participated in the survey was 686 males and 365 females, and the types of abused drugs and their perceptions of harmful effects of narcotics and abused drugs were analyzed according to gender. As a result of the study, the experience of using alcohol, tobacco, appetite suppressants, sedatives, and opioid analgesics was statistically significant according to gender. Among the harmful effects of narcotic drugs and drugs of abuse, significant results were shown on the recognition of risks, induced problems, and sympathy for risks. As for the desirable way to improve the problem of narcotics and substance abuse, 257 women (68.2%) of women wanted publicity (enlightenment) activities, and about effective education for preventing narcotics and substance abuse, 379 men (54.2%) of men %) appeared as online online education. It is considered that proper education and publicity about drug use is necessary in the reality that drug addiction among young people due to drug abuse is increasing.

Prevention and the characteristics of drug abusers among Japanese junior high school students : A comparative study of drug users and non-drug users (예방적 측면에서 본 일본 청소년의 약물남용자의 특징 -약물남용자와 비남용자의 비교 연구-)

  • Oh, Hak
    • Korean Journal of Health Education and Promotion
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    • v.11 no.2
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    • pp.57-67
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    • 1994
  • The aim of this study was to research and compare the demographic characteristics of drug abusers with non-drug abusers among junior high school students in Japan through a closed format questionnaire. The same questionnaire and face-to-face interviews were used in order to find the circumstances of drug abuser among Kyogoin(a sort of child welfare institution) students in Japan. The goal of the study was to provide basic materials for preventive education of drug abuse through the two investigations mentioned above. Between July 1993 and November 1993, the information for this study was collected from 964 students from 4 junior high schools, and also 142 students from 3 Kyogoin in Japan. A total of 1106 questionnaires were completed resulting in a following response rate of 90.4%. Information was based on the scales : family relation scale, school life scale, recognition on danger of drug abuse scale, family environment scale (Moos, 1986), self esteem inventory (Coopersmith, 1967), etc. The conclusions can be summarized as follows : 1. Drug abusers are more likely to lake communication in their families and have poorer human relations than non-drug abusers. Also their school life scores tended to be lawer non-drug abusers. 2. It was between their 6th year of elementary school and their first of Junior high school when the drug was first used. The drug of choice which they made their first attempt at using was a volatile solvent which was inhaled. It is likely that this drug is "gateway-drug" for adolescents in Japan because they then also tried other drugs (e.g. cocaine, marijuana, etc.) step by step. 3. It is therefore clearly important that greatly increasing education on the harmful effects of drug abuse before the summer vacation of the first term of the sixth year of elementary school. At the same time, intervention in the family will have an effective prevention strategy in Japan, as well., as well.

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Monitoring of Quality Characteristics and Harmful Substances in Commercial Handmade Soap (유통 수제비누의 품질특성 및 유해물질 모니터링)

  • Yeon Ji Kim;In Sook Lee;Su Ae Kim;Koth Bong Woo Ri Kim;Ho Cheol Yun;Pyeung Tae Gu
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.49 no.3
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    • pp.213-223
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    • 2023
  • A total of 81 handmade soaps on sale on the market were collected from January to November 2022. To compare quality characteristics, all ingredients were referred to, and the pH, dry reduction, heavy metals (lead, arsenic, cadmium, antimony, and mercury), and contents of free alkali were measured. All soaps had a slightly alkaline pH of 7.9 to 11.2, average drying loss was 17.6%, and free alkali was hardly detected. The average values of all heavy metals were 0.104 ㎍/g for lead, 0.035 ㎍/g for arsenic, 0.002 ㎍/g for cadmium, 0.048 ㎍/g for antimony, and 0.0003 ㎍/g for mercury. The results of handmade soap were below the recommended in regulations on safety standards for cosmetics of Ministry of Food and Drug Safety.

Development of Drug Utilization Review Guidelines for Therapeutic Duplication of Antipyretics, Analgesics, and Anti-inflammatory Drugs Registered in Korea (국내 허가된 해열.진통.소염제의 치료중복 주의 가이드라인 개발)

  • Lee, Young-Sook;Kim, Nam-Hyo;Sohn, Hyun-Soon;Choi, Kyung-Eob;Shin, Hyun-Taek
    • Korean Journal of Clinical Pharmacy
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    • v.20 no.3
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    • pp.213-220
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    • 2010
  • Therapeutic duplication (TD) is a serious problem that frequently occurring primarily in the ambulatory setting in Korea. Implementation of concurrent drug utilization review (DUR) is a promising way to reduce inappropriate prescription and dispensing, and improve patient safety. This study was aimed to develop the process of DUR module of TD. Sixty-five drug ingredients classified into the drug category of the antipyretic, analgesic, and anti-inflammatory drug approved in Korea (The KFDA-dess nated classification codes of 114 or 264) were reviewed for this purpose. The drug ingredients (and products) were reclassified based on WHO's Anatomical, Therapeutic and Chemical (ATC) classification system. The clinical practice guidelines, textbooks and product labels on therapeutic uses of these drugs in Korea and several fores n countries were reviewed. If the drugs were categorized into the same therapeutically duplicable class, they were defined not to be used concurrently because the concurrent use was "therapeutically duplicated (unnecessary or even harmful)". Among the studied drug products, the following 5 drug classes were considto beas "therapeutic duplication": (1), on-t tooid DURnti-inflammatory drugs (NSAIDs, including s Dicylates), (2),Anilidts, (3),Opioids, (4) Ergot Dk Doids and (5) 5-$HT_1$ receptor agonot s. Therefore, concurrent prescribing or dispensing of more than 2 drug ingredients any in the above same classes should be considered as TD and needed to be warrant for careful review by pharmacists before dispensing.

A Study on the Relationship between Adolescent Misconducts and Harmful Environment Based on Health Belief Model (건강신념모델을 적용한 청소년 비행과 유해환경과의 관련성 연구)

  • 이명선
    • Korean Journal of Health Education and Promotion
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    • v.18 no.3
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    • pp.37-58
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    • 2001
  • This study placed its objectives in suggesting the basic data for setting up an approach to protect the educational environment, by analyzing the relevance between the misconducts of adolescence and the harmful environment around the school, as an object of study, middle school students and high school students all over the country. Thus, this study carried out the questionnaire survey, by the multi-stage of stratified sampling in 2,114 middle school and high school students from June 29, 2000 through July 29, 2000. And the results of analysis were as follows: 1. In case of the ratio of students using harmful environment, the electronic game room had the highest ratio (78.3%); next, the PC room (75.6%), the singing room (71.6%), and the cartoon room (34.3%). 2. In terms of the experiences of using the harmful environment according to the personal characteristics, high school students used it in a higher ratio, compared with middle school students (p〈0.001); the students, whose father graduated from a high school, comparatively used it much more(p〈0.05). Also, when a school is located near to amusement quarters or shopping centers, students used the harmful environment most highly (p〈0.001). And the differences were found to be statistically significant. 3. In case of the perceived susceptibility factors, the harmful environment was found to be used in lower ratio, by the students who answered “very so” to the question item, The more harmful environment facilities are positioned around school, the more student have the opportunities to use them. (p〈0.001). That is, the findings showed that the higher students' degree of perceived susceptibility factors was the less students used harmful environment facilities. The differences were statistically significant. In terms of the ratio of using harmful environment according to perceived seriousness factors, it was founded out that the students, who answered, “If I use any harmful environment facilities, it will be very harmful to myself.”. had the less opportunities of having used them, compared with the students who did not answer so (p〈0.001). This indicated that the higher the degrees perceived seriousness of students, the less they used harmful environment facilities. And the differences were statistically significant. In the side of the ratio of using harmful environment according to the perceived barriers, it was found out that there were any special large differences. That is, perceived barriers had nothing to do with students' using harmful environment. 4. As the result of having analyzed the factors influencing the behaviors of using harmful environment, the factor to explain the behaviors of using harmful environment was found to be the degree of perceived seriousness, among individual perceiving factors; next, the location of a school - one of personal characteristics, the degree of perceived susceptibility and ages, m sequence. 5. Among students' misconduct experiences, drinking was highest (21.6%), next, smoking (11.9%), drug abuse (4.3%), and sexual relations (1.6%), In sequence. Among other problematic behaviors, excessive waste was highest (14.6%); next, disobedience and lie (10.7%), night wandering (7.8%), and bad dressing and making-up (5.5%), in sequence. 6. In terms of the misconducts according to the behaviors of using harmful environment, compared with the students who did not commit any misconducts, harmful environment facilities were used more highly, by each group of students who experienced drinking (p〈0.00l), smoking (p〈0.001), sexual relations (p〈0.05), excessive waste (p〈0.001), disobedience & lie (p〈0.001), and bad dressing & making-up (p〈0.05). And the differences were statistically significant.

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