• Title/Summary/Keyword: hER

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Control of Automatic Cargo Handling System Using ER Valves (II) -Modeling and Control of Cargo Handling System- (ER밸브를 이용한 자동 하역 시스템의 제어 (II) -하역시스템의 모델링 및 제어-)

  • Sung, Kum-Kil;Chung, Dar-Do;Choi, Seung-Bok
    • Journal of the Korean Society for Precision Engineering
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    • v.18 no.9
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    • pp.53-60
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    • 2001
  • This paper presents a position control of a platform at the seaport cargo handling system. After brief description of the operating principles of the cargo handling system, the governing equation of the moving platform is derived. The equation is described in the state space model, and a robust H$_{\infty}$ controller to achieve position tracking of the moving platform. which can carry 200ton of containers, is formulated. In the synthesis of the controller, the weight of the container is treated as uncertain parameter. Both regulating and tracking control responses are analyzed for the loading and unloading procedures of the proposed automatic cargo handling system.

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Core region and optical properties of Er3+ doped Y3Al5O12 single crystals (Er3+ doped Y3Al5O12 단결정의 core 영역 및 광학적 특성)

  • Shim, Jang Bo;Lee, Young Jin;Kang, Jin Ki;Lee, Young Kuk
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.25 no.3
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    • pp.111-115
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    • 2015
  • $Er^{3+}$ doped $Y_3Al_5O_{12}$ (Er:YAG) single crystals, in which the concentrations of $Er^{3+}$ ion were 5, 7.3, 8, and 10 at.%, were grown by the Czochralski method under nitrogen atmosphere. The <111> oriented Er:YAG single crystals with diameters of up to 50 mm were grown at a pulling rate of 1.0 mm/h and rotation rate of 10 rpm. The thick part of the core region was generated mainly when there was a diameter change during the crystal growth. The concentrations of $Er^{3+}$ ion in the crystals were the same as it was in the melt. $Er^{3+}$ concentration of core region was slightly higher than the other regions in the compositional analysis. The fluorescence lifetime was saturated according to the increase of $Er^{3+}$ doping concentrations.

Characterization of the cellular localization of C4orf34 as a novel endoplasmic reticulum resident protein

  • Jun, Mi-Hee;Jun, Young-Wu;Kim, Kun-Hyung;Lee, Jin-A;Jang, Deok-Jin
    • BMB Reports
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    • v.47 no.10
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    • pp.563-568
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    • 2014
  • Human genome projects have enabled whole genome mapping and improved our understanding of the genes in humans. However, many unknown genes remain to be functionally characterized. In this study, we characterized human chromosome 4 open reading frame 34 gene (hC4orf34). hC4orf34 was highly conserved from invertebrate to mammalian cells and ubiquitously expressed in the organs of mice, including the heart and brain. Interestingly, hC4orf34 is a novel ER-resident, type I transmembrane protein. Mutant analysis showed that the transmembrane domain (TMD) of hC4orf34 was involved in ER retention. Overall, our results indicate that hC4orf34 is an ER-resident type I transmembrane protein, and might play a role in ER functions including $Ca^{2+}$ homeostasis and ER stress.

Er(III)-chelated Prototype Complexes Based on Benzoate and Pentafluorobenzoate Ligands : Synthesis and Key Parameters for Near IR Emission Enhancement

  • Roh, Soo-Gyun;Oh, Jae-Buem;Nah, Min-Kook;Baek, Nam-Seob;Lee, Young-Il;Kim, Hwan-Kyu
    • Bulletin of the Korean Chemical Society
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    • v.25 no.10
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    • pp.1503-1507
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    • 2004
  • New synthetic methodology of the saturated and unsaturated Er(III)-chelated prototype complexes based on benzoate and pentafluorobenzoate ligands was developed through ligand-exchange reaction. The saturated 8-coordinated Er(III) complexes exhibit stronger near-IR emission than those of the unsaturated 6-coordinated Er(III) complexes, obtained from the direct photoexcitation of Er ions with 488 nm. Three $H_2O$ molecules coordinated in the unsaturated 6-coordinated complexes seriously quenched the near IR emission by the harmonic vibration relaxation decay of O-H bonds. Also, the stronger emission of the Er(III) complexes was obtained by the indirect photoexcitation of ligands than by the direct photoexcitation of the Er(III) ions, due to the energy transfer between the excited ligand and the erbium ion. Furthermore, the saturated Er(III)-chelated complex with C-F bonds shows much stronger near IR emission than that of the saturated Er(III)-chelated complex with C-H bonds. It is attributed to the influence of C-F bonds on near IR emission.

Effects of HIF-1α/VP16 Hybrid Transcription Factor on Estrogen Receptor in MCF-7 Human Breast Cancer Cells

  • Cho, Jung-Yoon;Park, Mi-Kyung;Lee, Young-Joo
    • Biomolecules & Therapeutics
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    • v.13 no.4
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    • pp.227-231
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    • 2005
  • The estrogen receptor (ER) is activated and degraded by estrogen. We have examined ER downregulation and activation under hypoxia mimetic conditions. Cobalt chloride induced ER downregulation at 24 h of treatment. This degradation involved hypoxia-inducible factor-1$\alpha$ (HIF-1$\alpha$) as examined by using a constitutively active form of HIF-1$\alpha$, HIF-1$\alpha$/VP16, constructed by replacing the transactivation domain of HIF-1$\alpha$ with that of VP16. Western blot analysis revealed that E2-induced ER downregulation was observed within ${\~}6h$, whereas HIF-1$\alpha$/VP16-induced ER degradation was observed within 12${\~}$20h. HIF-1$\alpha$/VP16 activated the transcription of estrogen-responsive reporter gene in the absence of estrogen. These results suggest that ER downregulation and activation under hypoxia maybe mediated in part by a HIP-1$\alpha$ expression.

Position Tracking Control of a Moving Table Using ER Brake/Clutch (ER 브레이크 및 클러치를 이용한 이송 테이블의 위치추적제어)

  • Choi, S.B.;Lee, H.G.;Kim, S.L.;Cheong, C.C.;Han, M.S.
    • Journal of the Korean Society for Precision Engineering
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    • v.15 no.11
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    • pp.208-217
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    • 1998
  • 본 연구에서는 ER 브레이크와 ER클러치를 피드백작동기로 사용하여 이송테이블의 위치 추적제어를 수행하였다. 이를 위해 먼저 아라빅 검(arabic gum)계통의 ER유체를 자체조성한 후 전기장에 대한 빙햄(Bingham)모델을 실험적으로 도출하였다. 빙햄모델에 근거하여 평판형의 ER브레이크와 실린더형의 ER클러치를 설계 제작하였으며, 계단입력(step input)전기장에 따른 출력토오크특성을 통하여 이들 작동기의 동적모델을 얻었다. 이들 작동기와 연계된 이송테이블시스템의 운동지배방정식을 유도한 후 위치추적제어를 위한 슬라이딩모드제어기를 설계하였다. 제어기 설계시 이송해이블의 부하질량 변화에 대한 시스템 불확실성과 마찰력을 고려하여 제어성능의 강건성을 보장하도록 하였다. 제안된 제어시스템의 제어영역(control bandwidth)을 주파수 영역에서 고찰한 후 여러 레적에 대한 위치추적제어 실험을 수행하였다.

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The Photoluminescence Properties of Er doped Alumina Sol-Gel Films Coated on Si Substrates (Er이 도핑된 알루미나 졸-겔 코팅막의 광발광 특성)

  • 권정오;황영영;김재홍;석상일
    • Proceedings of the Materials Research Society of Korea Conference
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    • 2003.03a
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    • pp.223-223
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    • 2003
  • 광통신에는 광신호의 전송과 광신호 처리에 처리 과정에서 광 손실을 수반하므로 각 요소별로 광신호 증폭이 반드시 필요하다. 또한 광통신망의 완전 광화를 위해서는 제조 공정이 간단하여 가격이 저렴하고, 높은 신뢰성과 높은 증폭 효율을 가지면서 다른 부품과의 집적화가 가능한 광도파로형 광증폭기가 요구되고 있다 그러나 실리카는 광통신 파장대인 1.55$\mu\textrm{m}$대역의 증폭이 가능한 Er 이온에 대한 용해도가 50ppm 이하로 낮아 lmol% 이상 고농도로 Er 이온을 첨가하여 높은 증폭 효율을 얻는데 한계를 가지고 있다. 따라서 본 연구에서는 Er 이온에 대하여 높은 용해 특성을 가지고 있어 고농도 Er 이온 도핑이 가능한 알루미나에 Er을 1-2 mol% 첨가하여 광발광 특성을 조사하였다. Er이 첨가된 알루미나 나노 졸은 Al(NO$_3$)$_3$ㆍ9$H_2O$와 Er(NO$_3$)$_3$.5$H_2O$가 일정 양 용해된 수용액에 NH$_4$OH를 가하여 침전물을 얻고 여과 및 수세하여 졸 입자의 함량이 약 5wt%가 되게 이온교환수와 해교제인 초산을 소량 가하여 10$0^{\circ}C$에서 약 50시간 열처리하는 방법으로 제조하였다. Er이 첨가된 알루미나 코팅막은 Er 이 첨가된 알루미나 나노 졸에 GPS(3-glycidoxypropyltriethoxysilane)를 Al에 대하여 7 mol% 가하여 스핀 코팅법으로 제조하였다. Si 기판에 코팅하고, 상온에서 90$0^{\circ}C$까지 각 1시간 열처리한 코팅막의 광 발광 특성은 Er 이온의 첨가량과 열처리로 변화된 알루미나 코팅막의 결정상과 연계하여 논의 될 것이다. X-선 회절법으로 분석한 알루미나 코팅막의 온도에 따른 결정상은 boehmite 상에서 약 50$0^{\circ}C$이후에 ${\gamma}$-Al$_2$O$_3$로 전이하고 있다.

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ZnO-$Pr_{6}O_{11}-CoO-Er_{2}O_{3}$ Based Ceramics Varistors with High Stability under d.c. stress (d.c. 스트레스에 높은 안정성을 갖는 ZnO-$Pr_{6}O_{11}-CoO-Er_{2}O_{3}$계 세라믹 바리스터)

  • Park, Choon-Hyun;Yoon, Han-Soo;Nahm, Choon-Woo
    • Proceedings of the KIEE Conference
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    • 1999.11d
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    • pp.1003-1007
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    • 1999
  • This paper is reported for the stability of ZnO-$Pr_{6}O_{11}-CoO-Er_{2}O_{3}$ based ceramic varistors with $Er_{2}O_{3}$ added in the addition range 0.0 to 2.0 mol%. The varistors sintered at $130^{\circ}C$ exhibited abrupt positive current creep phenomena, which accompany thermal run away within short times, even under weak d.c. stress. As a result, these varistors were completely degraded. On the contrary, the stability of varistors sintered at $1350^{\circ}C$ was far better than that of $1300^{\circ}C$. In particular, the varistor containing 0.5 mol% $Er_{2}O_{3}$ showed a excellent stability, which the variation rate of the varistor voltage, the nonlinear coefficient, and leakage current is below 1%, 2%, and 3.5%, respectively, even under more severe d.c. stress, such as ($0.8V_{1mA}/90^{\circ}C/12h$) + ($0.85V_{1mA}/115^{\circ}C/12h$) + ($0.9V_{1mA}/120^{\circ}C/12h$) + ($0.9V_{1mA}/150^{\circ}C/12h$). Consequently, it is estimated that the basic composition of ZnO-$Pr_{6}O_{11}-CoO-Er_{2}O_{3}$ based varistor contain 0.5 mol% $Er_{2}O_{3}$ will be used to the fabrication of the varistors for high performance and stability in a forthcoming.

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Role of Osmotic and Salt Stress in the Expression of Erythrose Reductase in Candida magnoliae

  • Park, Eun-Hee;Lee, Ha-Yeon;Ryu, Yeon-Woo;Seo, Jin-Ho;Kim, Myoung-Dong
    • Journal of Microbiology and Biotechnology
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    • v.21 no.10
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    • pp.1064-1068
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    • 2011
  • The osmotolerant yeast, Candida magnoliae, which was isolated from honeycomb, produces erythritol from sugars such as fructose, glucose, and sucrose. Erythrose reductase in C. magnoliae (CmER) reduces erythrose to erythritol with concomitant oxidation of NAD(P)H. Sequence analysis of the 5'-flanking region of the CmER gene indicated that one putative stress response element (STRE, 5'-AGGGG-3'), found in Saccharomyces cerevisiae, exists 72 nucleotides upstream of the translation initiation codon. An enzyme activity assay and semiquantitative reverse transcription polymerase chain reaction revealed that the expression of CmER is upregulated under osmotic and salt stress conditions caused by a high concentration of sugar, KCl, and NaCl. However, CmER was not affected by osmotic and oxidative stress induced by sorbitol and $H_2O_2$, respectively. The basal transcript level of CmER in the presence of sucrose was higher than that in cells treated with fructose and glucose, indicating that the response of CmER to sugar stress is different from that of GRE3 in S. cerevisiae, which expresses aldose reductase in a sugarindependent manner. It was concluded that regulation of CmER differs from that of other aldose reductases in S. cerevisiae.

Position control fo a flexible gantry robot arm using smart actuators (스마트 작동기를 이용한 갠트리형 유연로봇팔의 위치제어)

  • 한상수;최승복
    • 제어로봇시스템학회:학술대회논문집
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    • 1997.10a
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    • pp.1800-1803
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    • 1997
  • This paper presents new feedback actuators to achieve an accurate position control of a flexible gnatry robot arm. the translational motion in the plane is generated by two d.c.motors and controlled by emplying elecor-rheological(ER) clutch acutators. The generated motion can be continuously controlled by controlling the intensity of lectric field imposed to the ER fluid domain which tunes the transmitted torque of the ER clutch. n the other hand, during control action of the translational motion a flexible arm attached to the moving mass produces undesirable oscillatins due to its inherent flexibility. The oscillations are actively suppressed by applying feedback voltages to piezoceramic acutators bonded on the surface of the flexible arm. The control electric fields to be applied to the ER clutch and the control voltage for the piezoceramic actuator are determined via the loop shaping esign procedures(LSDP) in the H.inf. control technique. Comsequently, an accuate positiion control at the end-point of the flexible am is achieved during planar motion.

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