• Child Health Nursing Research
• /
• v.17 no.2
• /
• pp.74-83
• /
• 2011

Purpose: The purpose of this study was to develop a child health care protocol for teachers in child day care centers. Methods: The ADDIE model with 10 Kid Keys was applied to develop this child health care protocol. All contents were developed through content validity test by 7 professionals and need assessment and evaluation by child day care center teachers. Results: This protocol consisted of 10 keys, as follows: "Health Examination/Growth & Development", "Practice of Health Life", "Management of Communicable Disease", "Negligent Accident", "Coping with Emergency and Transference", "Child Abuse", "Nutrition/Obesity", "Quality Assurance of Staff", "Parent Education", "Guidance & Supervision of Child Day Care Centers". The contents contained goals, objectives, teaching content, suggested activities for children, writing forms related to each subject, and self-evaluation sheet. Conclusion: This protocol can be practical and effective for child health care in child day care centers and it is hoped that it will be utilized in more child day care centers.

• Molecules and Cells
• /
• v.37 no.5
• /
• pp.357-364
• /
• 2014

Medulloblastoma, the most common malignant brain tumor in children, is a disease whose mechanisms are now beginning to be uncovered by high-throughput studies of somatic mutations, mRNA expression patterns, and epigenetic profiles of patient tumors. One emerging theme from studies that sequenced the tumor genomes of large cohorts of medulloblastoma patients is frequent mutation of RNA binding proteins. Proteins which bind multiple RNA targets can act as master regulators of gene expression at the post-transcriptional level to co-ordinate cellular processes and alter the phenotype of the cell. Identification of the target genes of RNA binding proteins may highlight essential pathways of medulloblastomagenesis that cannot be detected by study of transcriptomics alone. Furthermore, a subset of RNA binding proteins are attractive drug targets. For example, compounds that are under development as anti-viral targets due to their ability to inhibit RNA helicases could also be tested in novel approaches to medulloblastoma therapy by targeting key RNA binding proteins. In this review, we discuss a number of RNA binding proteins, including Musashi1 (MSI1), DEAD (Asp-Glu-Ala-Asp) box helicase 3 X-linked (DDX3X), DDX31, and cell division cycle and apoptosis regulator 1 (CCAR1), which play potentially critical roles in the growth and/or maintenance of medulloblastoma.

• Proceedings of the Korea Information Processing Society Conference
• /
• 2023.05a
• /
• pp.687-688
• /
• 2023

Bone age assessment is a crucial task in pediatric radiology for assessing growth and development in children. In this paper, we explore the potential of Vision Transformer, a state-of-the-art deep learning model, for bone age assessment using X-ray images. We generate heatmap outputs using a pre-trained Vision Transformer model on a publicly available dataset of hand X-ray images and show that the model tends to focus on the overall hand and only the bone part of the image, indicating its potential for accurately identifying the regions of interest for bone age assessment without the need for pre-processing to remove background noise. We also suggest two methods for extracting the region of interest from the heatmap output. Our study suggests that Vision Transformer holds great potential for bone age assessment using X-ray images, as it can provide accurate and interpretable output that may assist radiologists in identifying potential abnormalities or areas of interest in the X-ray image.

• Korean Institute of Interior Design Journal
• /
• v.25 no.5
• /
• pp.63-70
• /
• 2016

Modern society is suffering from the phenomena of low-fertile, ultra-aging, and low-growth. On this social flow, most social classes undergo vulnerable situation and their overall housing and living condition have difficulties. So far many housing guidelines for diverse population were developed, recently, inclusive 'Customized Housing Design Guideline for Childcare Families' in terms of maintaining family and society has been completed. The purpose of this study is to analyze User Benefit Characteristics of 'Customized Housing Design Guideline for Childcare Families'. The research subjects are essential 140 guidelines appropriate to children's development and parents' care. The research method is contents analysis and the analysis criterion are 4 concepts of the User Benefit Criteria- 'Behavioral Facilitation (BF)', 'Physiological Maintenance (PhM)', 'Perceptual Maintenance (PM)', 'Social Facilitation (SF)'. 3 people inter-raters reliability was established. Altogether, the guidelines were rated in the order of PhM>PM>BF>SF, and these characteristics are similar as common universal design guidelines. This showed the supportability of spatial characteristics in the guidelines related to user's special behaviors. Also, the results show the importance of outdoor space planning for safe social interactions. The supportable characteristics of 'Customized Housing Design Guideline for Childcare Families' could be expected to efficiently apply for new housing development in the future.

• Journal of Yeungnam Medical Science
• /
• v.20 no.2
• /
• pp.223-228
• /
• 2003

Calcifying aponeurotic fibroma is a rare benign soft tissue tumor that usually involves distal extremities in children and adolescents, especially the hands and feet. We report a case of calcifying aponeurotic fibroma arising in a 14-year-old boy who complained of right thumb mass. Surgical excision was performed. The resected specimen showed a $2.0{\times}1.5cm$ grayish white, fibrotic tissue. Histologic examination showed proliferation of fibroblastic cells with infiltrative growth pattern. Foci of calcification and chondroid differentiation were present.

• Korean Journal of Childcare and Education
• /
• v.18 no.5
• /
• pp.57-77
• /
• 2022

Objective: The purpose of this study was to analyze the causal relationship between parenting knowledge, parenting stress, and parenting behavior of mothers with infants and to confirm the longitudinal mediating effect of parenting stress in the relationship between parenting knowledge and parenting behavior. Methods: This study used data collected through the Panel Study on Korean Children from 2008 to 2010 and the participants were 1,444 mothers with infants. The data were analyzed through technical statistics, correlations and multivariate potential growth models using SPSS 28.0 and AMOS 26.0. Results: Parenting knowledge and parenting stress of mothers gradually increased, and positive parenting behavior gradually decreased. Having a lot of parenting knowledge reduced mother's parenting stress. Mother's parenting stress reduced positive parenting behavior, and as parenting stress increased, positive parenting behavior decreased significantly. However, the relationship between parenting knowledge and parenting behavior was not significant. In addition, the mediating effect of parenting stress was confirmed in the relationship between parenting knowledge and parenting behavior of mothers. Conclusion/Implications: The results of this study suggest the need to reduce parenting stress and promote positive parenting behavior along with the systematization of parent education programs in order for mothers with infants to acquire parenting knowledge.

• Clinical and Experimental Pediatrics
• /
• v.50 no.6
• /
• pp.519-523
• /
• 2007

Aplastic anemia is a rare disease, which is characterized by pancytopenia and hypocellular bone marrow without infiltration of abnormal cells or fibrosis. The incidence in Asia is higher than in the West and new cases are diagnosed at a rate of 5.1 per million pediatric populations per year in Korea. The pathophysiology is understood roughly by defective hematopoiesis, impaired bone marrow micro-environment and immune mechanism. Treatments are performed on basis of pathogenesis and selected depending on the severity. Immunosuppressive therapy with antilymphocyte or antithymocyte globulin and cyclosporine is effective in the majority of patients but has some problems including relapse or clonal evolution. Recently, there have been clinical trials of immunosuppression with hematopoietic growth factors or other drugs. Allogeneic hematopoietic stem cell transplantation (HSCT) is curative in children with severe aplastic anemia. The overall survival in HSCT from HLA-identical sibling is higher than alternative donor, including HLA matched unrelated donor or cord blood. We have to consider quality of life after HSCT because of high survival rate. However, chronic graft versus host disease and graft failure are important factors that affect the quality of life and overall survival. We need further investigation to make new regimens aimed at overcoming these risk factors and perform clinical trials.

• Journal of the Korean housing association
• /
• v.25 no.5
• /
• pp.1-10
• /
• 2014

In the upcoming 21st century, we predict change and development in various aspects. Some fundamental causes of change in housing lifestyles such as the change in family make-up are gradually becoming more and more realistic problems as the society is shifting to the younger generation family make up refer to the rapid increase of the agedpopulation, growth of single households, the drop in the number of family members, the change in the economic situation and technology level, and change in values. The purpose of this research is to, more away from the standardized supply of housing and to approach apartment housing plans in multilateral aspects, compare and analyze the difference between the housing demands of different generations and the influence that the current housing type has on demand forecasting by case studies of Unit Living Space planning that we will utilize the participating design method in which parents and children took part in.

• The Mathematical Education
• /
• v.44 no.2 s.109
• /
• pp.265-280
• /
• 2005

According to the characteristics of elementary school students in favor of playing games, and to their high energy levels and physical growth states, it is fair to say that students can learn mathematics through 'game playing activities.' These activities are considered to intrigue their interest in class and make them feel less stress from the burden of studying mathematics. Mr. Skemp, who had conducted research on 'game activity' with experimental studies relating to elementary mathematics, recommends that math teachers try to give as many activity-oriented classes as possible to students. The method of 'game activity' by Skemp's operation deals with the whole range of mathematical themes. It is believed by other math teachers that this is not a way to substitute free time or just to have fun in class, but an intentionally well-organized way of learning an entire mathematical course during elementary school. In this research, 5th and 6th grade students needing extra classes after school had been exposed to 'ame activity' by Skemp's operation. As a result, we can figure out its influence on their understanding of arithmetic ability, and on the cognitive definition territory in their minds.

• Journal of the Korean Society of Clothing and Textiles
• /
• v.27 no.1
• /
• pp.143-153
• /
• 2003

This study was conducted in order to provide basic study material for children's garment design. The subjects of this study are fifth and sixth grade elementary school girls, who demonstrate rapid growth and the differences among individual somatic types are apparent. Their bodies are studied, categorized into patterns and the characteristics are examined. 1 The increase of height and length measurements according to age increase are much larger than that of breadth, depth and girth menasurments. 2. Eight factors are drawn upon factor analysis and the rate of factors comprisedare 78.68%. 3. The shapes of lower body of higher grades girls in elementary school are classified into three categories. The first type is slender in lower body and the second type is more contoured around waist area with longer length and higher height than the average elementary school girls. The third type is heavy in the lower body. 4. Eighteen items important for somatic categorization are selected through stepwise discriminant analysis and the exactitude rate of these items is 93.3%.